Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Overweight D050177 11 associated lipids
Headache Disorders, Secondary D051271 1 associated lipids
Orthostatic Intolerance D054971 1 associated lipids
Vascular System Injuries D057772 2 associated lipids
Acute Pain D059787 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Authors Title Published Journal PubMed Link
Weidenfeld J et al. Effect of the brain constituent anandamide, a cannabinoid receptor agonist, on the hypothalamo-pituitary-adrenal axis in the rat. 1994 Neuroendocrinology pmid:8127398
Childers SR et al. Effects of anandamide on cannabinoid receptors in rat brain membranes. 1994 Biochem. Pharmacol. pmid:8129747
Devane WA New dawn of cannabinoid pharmacology. 1994 Trends Pharmacol. Sci. pmid:8165721
Iversen L Pharmacology. Endogenous cannabinoids. 1994 Nature pmid:7990950
Van der Kloot W Anandamide, a naturally-occurring agonist of the cannabinoid receptor, blocks adenylate cyclase at the frog neuromuscular junction. 1994 Brain Res. pmid:7953630
Schwarz H et al. Anadamide, an endogenous cannabinoid receptor agonist inhibits lymphocyte proliferation and induces apoptosis. 1994 J. Neuroimmunol. pmid:7962480
Di Marzo V et al. Formation and inactivation of endogenous cannabinoid anandamide in central neurons. 1994 Nature pmid:7990962
Schuel H et al. Anandamide (arachidonylethanolamide), a brain cannabinoid receptor agonist, reduces sperm fertilizing capacity in sea urchins by inhibiting the acrosome reaction. 1994 Proc. Natl. Acad. Sci. U.S.A. pmid:8052642
Smith PB et al. The pharmacological activity of anandamide, a putative endogenous cannabinoid, in mice. 1994 J. Pharmacol. Exp. Ther. pmid:8035318
Koutek B et al. Inhibitors of arachidonoyl ethanolamide hydrolysis. 1994 J. Biol. Chem. pmid:8083191
Kruszka KK and Gross RW The ATP- and CoA-independent synthesis of arachidonoylethanolamide. A novel mechanism underlying the synthesis of the endogenous ligand of the cannabinoid receptor. 1994 J. Biol. Chem. pmid:8182035
Devane WA and Axelrod J Enzymatic synthesis of anandamide, an endogenous ligand for the cannabinoid receptor, by brain membranes. 1994 Proc. Natl. Acad. Sci. U.S.A. pmid:8022836
Hillard CJ et al. Characterization of the kinetics and distribution of N-arachidonylethanolamine (anandamide) hydrolysis by rat brain. 1995 Biochim. Biophys. Acta pmid:7647100
Hampson AJ et al. Anandamide hydroxylation by brain lipoxygenase:metabolite structures and potencies at the cannabinoid receptor. 1995 Biochim. Biophys. Acta pmid:7488638
Burstein SH and Hunter SA Stimulation of anandamide biosynthesis in N-18TG2 neuroblastoma cells by delta 9-tetrahydrocannabinol (THC). 1995 Biochem. Pharmacol. pmid:7702643
Priller J et al. Mead ethanolamide, a novel eicosanoid, is an agonist for the central (CB1) and peripheral (CB2) cannabinoid receptors. 1995 Mol. Pharmacol. pmid:7651362
Collin C et al. Long-term synaptic transformation of hippocampal CA1 gamma-aminobutyric acid synapses and the effect of anandamide. 1995 Proc. Natl. Acad. Sci. U.S.A. pmid:7479747
Hansen HS et al. Glutamate stimulates the formation of N-acylphosphatidylethanolamine and N-acylethanolamine in cortical neurons in culture. 1995 Biochim. Biophys. Acta pmid:7548201
Romero J et al. Time-course of the effects of anandamide, the putative endogenous cannabinoid receptor ligand, on extrapyramidal function. 1995 Brain Res. pmid:8974649
Ueda N et al. Lipoxygenase-catalyzed oxygenation of arachidonylethanolamide, a cannabinoid receptor agonist. 1995 Biochim. Biophys. Acta pmid:7827116