Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Urinary Bladder Diseases D001745 4 associated lipids
Ataxia D001259 20 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Anorexia D000855 8 associated lipids
Alzheimer Disease D000544 76 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Edgemond WS et al. The binding of novel phenolic derivatives of anandamide to brain cannabinoid receptors. 1995 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:7784462
Mechoulam R Discovery of endocannabinoids and some random thoughts on their possible roles in neuroprotection and aggression. 2002 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:12052029
Sugiura T et al. Biosynthesis and degradation of anandamide and 2-arachidonoylglycerol and their possible physiological significance. 2002 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:12052034
Fowler CJ and Jacobsson SO Cellular transport of anandamide, 2-arachidonoylglycerol and palmitoylethanolamide--targets for drug development? 2002 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:12052035
Deutsch DG et al. The fatty acid amide hydrolase (FAAH). 2002 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:12052036
Fride E Endocannabinoids in the central nervous system--an overview. 2002 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:12052038
Pinto L et al. Endocannabinoids and the gut. 2002 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:12052047
Högestätt ED and Zygmunt PM Cardiovascular pharmacology of anandamide. 2002 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:12052048
Di Marzo V et al. Anandamide receptors. 2002 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:12052051
Kim HY and Spector AA Synaptamide, endocannabinoid-like derivative of docosahexaenoic acid with cannabinoid-independent function. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:22959887
Iannotti FA et al. Analysis of the "endocannabinoidome" in peripheral tissues of obese Zucker rats. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:23830028
Fontana A et al. Analysis of anandamide, an endogenous cannabinoid substance, and of other natural N-acylethanolamines. 1995 Prostaglandins Leukot. Essent. Fatty Acids pmid:8577784
Jarrahian A and Hillard CJ Arachidonylethanolamide (anandamide) binds with low affinity to dihydropyridine binding sites in brain membranes. 1997 Prostaglandins Leukot. Essent. Fatty Acids pmid:9431821
Johannesson M et al. Cloning, purification and characterization of non-human primate 12/15-lipoxygenases. 2010 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:20106647
Boring DL et al. Cerebrodiene, arachidonyl-ethanolamide, and hybrid structures: potential for interaction with brain cannabinoid receptors. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8931121
Chen P et al. Metabolism of anandamide in cerebral microvascular endothelial cells. 2004 Prostaglandins Other Lipid Mediat. pmid:15165032
Wang J and Ueda N Biology of endocannabinoid synthesis system. 2009 Prostaglandins Other Lipid Mediat. pmid:19126434
Kim HY et al. A synaptogenic amide N-docosahexaenoylethanolamide promotes hippocampal development. 2011 Prostaglandins Other Lipid Mediat. pmid:21810478
Wang H et al. Differential regulation of endocannabinoid synthesis and degradation in the uterus during embryo implantation. 2007 Prostaglandins Other Lipid Mediat. pmid:17259073
Fonseca BM et al. Endogenous cannabinoids revisited: a biochemistry perspective. 2013 Apr-May Prostaglandins Other Lipid Mediat. pmid:23474290
Hillard CJ Biochemistry and pharmacology of the endocannabinoids arachidonylethanolamide and 2-arachidonylglycerol. 2000 Prostaglandins Other Lipid Mediat. pmid:10785538
Burstein SH et al. Oxidative metabolism of anandamide. 2000 Prostaglandins Other Lipid Mediat. pmid:10785540
Di Marzo V et al. Cannabimimetic fatty acid derivatives in cancer and inflammation. 2000 Prostaglandins Other Lipid Mediat. pmid:10785541
Kunos G et al. Cardiovascular effects of endocannabinoids--the plot thickens. 2000 Prostaglandins Other Lipid Mediat. pmid:10785543
McCue JM et al. In vitro synthesis of arachidonoyl amino acids by cytochrome c. 2009 Prostaglandins Other Lipid Mediat. pmid:19683594
Nicotra LL et al. Prostaglandin ethanolamides attenuate damage in a human explant colitis model. 2013 Prostaglandins Other Lipid Mediat. pmid:23380599
Besana A et al. Lipids and two-pore domain K+ channels in excitable cells. 2005 Prostaglandins Other Lipid Mediat. pmid:16099395
van der Stelt M and Di Marzo V Anandamide as an intracellular messenger regulating ion channel activity. 2005 Prostaglandins Other Lipid Mediat. pmid:16099396
Mimeault M et al. Anti-proliferative and apoptotic effects of anandamide in human prostatic cancer cell lines: implication of epidermal growth factor receptor down-regulation and ceramide production. 2003 Prostate pmid:12746841
Basavarajappa BS Critical enzymes involved in endocannabinoid metabolism. 2007 Protein Pept. Lett. pmid:17346227
Heyman E et al. Intense exercise increases circulating endocannabinoid and BDNF levels in humans--possible implications for reward and depression. 2012 Psychoneuroendocrinology pmid:22029953
Hill MN et al. Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress. 2009 Psychoneuroendocrinology pmid:19394765
Gray JM et al. Sustained glucocorticoid exposure recruits cortico-limbic CRH signaling to modulate endocannabinoid function. 2016 Psychoneuroendocrinology pmid:26821211
Marco EM et al. Emotional, endocrine and brain anandamide response to social challenge in infant male rats. 2013 Psychoneuroendocrinology pmid:23660109
Fride E and Mechoulam R Developmental aspects of anandamide: ontogeny of response and prenatal exposure. 1996 Psychoneuroendocrinology pmid:8774060
Kaufmann I et al. Anandamide and neutrophil function in patients with fibromyalgia. 2008 Psychoneuroendocrinology pmid:18395993
Hill MN et al. Reductions in circulating endocannabinoid levels in individuals with post-traumatic stress disorder following exposure to the World Trade Center attacks. 2013 Psychoneuroendocrinology pmid:24035186
Schindler CW et al. Self-administration of the anandamide transport inhibitor AM404 by squirrel monkeys. 2016 Psychopharmacology (Berl.) pmid:26803499
Naidu PS et al. Evaluation of fatty acid amide hydrolase inhibition in murine models of emotionality. 2007 Psychopharmacology (Berl.) pmid:17279376
Panlilio LV et al. Effects of fatty acid amide hydrolase (FAAH) inhibitors on working memory in rats. 2016 Psychopharmacology (Berl.) pmid:26558620
Fernandez-Espejo E and Galan-Rodriguez B Sensorimotor gating in mice is disrupted after AM404, an anandamide reuptake and degradation inhibitor. 2004 Psychopharmacology (Berl.) pmid:15088080
Mallet PE and Beninger RJ The cannabinoid CB1 receptor antagonist SR141716A attenuates the memory impairment produced by delta9-tetrahydrocannabinol or anandamide. 1998 Psychopharmacology (Berl.) pmid:9862397
Cassano T et al. Evaluation of the emotional phenotype and serotonergic neurotransmission of fatty acid amide hydrolase-deficient mice. 2011 Psychopharmacology (Berl.) pmid:21042794
Higgs S et al. Cannabinoid influences on palatability: microstructural analysis of sucrose drinking after delta(9)-tetrahydrocannabinol, anandamide, 2-arachidonoyl glycerol and SR141716. 2003 Psychopharmacology (Berl.) pmid:12447606
Cross-Mellor SK et al. Effects of the FAAH inhibitor, URB597, and anandamide on lithium-induced taste reactivity responses: a measure of nausea in the rat. 2007 Psychopharmacology (Berl.) pmid:17111174
Morera-Herreras T et al. Nigrostriatal denervation changes the effect of cannabinoids on subthalamic neuronal activity in rats. 2011 Psychopharmacology (Berl.) pmid:20959968
Aliczki M et al. Involvement of 2-arachidonoylglycerol signaling in social challenge responding of male CD1 mice. 2015 Psychopharmacology (Berl.) pmid:25547462
Mangieri RA et al. An endocannabinoid signal associated with desire for alcohol is suppressed in recently abstinent alcoholics. 2009 Psychopharmacology (Berl.) pmid:19343330
Panlilio LV et al. Anandamide-induced behavioral disruption through a vanilloid-dependent mechanism in rats. 2009 Psychopharmacology (Berl.) pmid:19015836
Schacht JP et al. Intermediate cannabis dependence phenotypes and the FAAH C385A variant: an exploratory analysis. 2009 Psychopharmacology (Berl.) pmid:19002671