Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Orthostatic Intolerance D054971 1 associated lipids
Schistosomiasis japonica D012554 3 associated lipids
Sleep Disorders, Intrinsic D020919 1 associated lipids
Headache Disorders, Secondary D051271 1 associated lipids
Acute Pain D059787 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Authors Title Published Journal PubMed Link
Pate DW et al. Effect of the CB1 receptor antagonist, SR141716A, on cannabinoid-induced ocular hypotension in normotensive rabbits. 1998 Life Sci. pmid:9851310
Wiley JL et al. Evaluation of the role of the arachidonic acid cascade in anandamide's in vivo effects in mice. 2006 Life Sci. pmid:16978656
Mallet PE and Beninger RJ Delta9-tetrahydrocannabinol, but not the endogenous cannabinoid receptor ligand anandamide, produces conditioned place avoidance. 1998 Life Sci. pmid:9651110
Holt S et al. Lipopolysaccharide-induced pulmonary inflammation is not accompanied by a release of anandamide into the lavage fluid or a down-regulation of the activity of fatty acid amide hydrolase. 2004 Life Sci. pmid:15530507
Forsell PK et al. Metabolism of anandamide into eoxamides by 15-lipoxygenase-1 and glutathione transferases. 2012 Lipids pmid:22684912
Di Marzo V et al. Metabolism of anandamide and 2-arachidonoylglycerol: an historical overview and some recent developments. 1999 Lipids pmid:10419192
Hansen HS et al. Formation of N-acyl-phosphatidylethanolamine and N-acylethanolamine (including anandamide) during glutamate-induced neurotoxicity. 1999 Lipids pmid:10419193
Schmid PC et al. Anandamide and other N-acylethanolamines in human tumors. 2002 Lipids pmid:12458627
Alvheim AR et al. Dietary linoleic acid elevates the endocannabinoids 2-AG and anandamide and promotes weight gain in mice fed a low fat diet. 2014 Lipids pmid:24081493
Naccarato M et al. Possible Anandamide and Palmitoylethanolamide involvement in human stroke. 2010 Lipids Health Dis pmid:20470384
Berge K et al. Chronic treatment with krill powder reduces plasma triglyceride and anandamide levels in mildly obese men. 2013 Lipids Health Dis pmid:23706001
Annuzzi G et al. Differential alterations of the concentrations of endocannabinoids and related lipids in the subcutaneous adipose tissue of obese diabetic patients. 2010 Lipids Health Dis pmid:20426869
Quartu M et al. Involvement of the endocannabinoid system in the physiological response to transient common carotid artery occlusion and reperfusion. 2017 Lipids Health Dis pmid:28103941
Yang YY et al. Inhibition of hepatic tumour necrosis factor-alpha attenuates the anandamide-induced vasoconstrictive response in cirrhotic rat livers. 2009 Liver Int. pmid:19413671
Caraceni P et al. Circulating and hepatic endocannabinoids and endocannabinoid-related molecules in patients with cirrhosis. 2010 Liver Int. pmid:19840245
Yang YY et al. Role of Ca2+-dependent potassium channels in in vitro anandamide-mediated mesenteric vasorelaxation in rats with biliary cirrhosis. 2007 Liver Int. pmid:17845532
Ying-Ying Y and Lin HC Endocannabinoids and non-endocannabinoid fatty acid amides in cirrhosis. 2010 Liver Int. pmid:20408944
Fernández-Rodriguez CM et al. Circulating endogenous cannabinoid anandamide and portal, systemic and renal hemodynamics in cirrhosis. 2004 Liver Int. pmid:15482346
Piyanova A et al. Age-related changes in the endocannabinoid system in the mouse hippocampus. 2015 Mech. Ageing Dev. pmid:26278494
Zohrabi-Kalantari V et al. 4-Aminocyclopentane-1,3-diols as platforms for diversity: synthesis of anandamide analogs. 2013 Med Chem pmid:23157226
Schlabritz-Loutsevitch N et al. Fetal Syndrome of Endocannabinoid Deficiency (FSECD) In Maternal Obesity. 2016 Med. Hypotheses pmid:27959272
Coppola M and Mondola R Palmitoylethanolamide: from endogenous cannabimimetic substance to innovative medicine for the treatment of cannabis dependence. 2013 Med. Hypotheses pmid:23896215
Kudalkar SN et al. Assay of Endocannabinoid Oxidation by Cyclooxygenase-2. 2016 Methods Mol. Biol. pmid:27245906
van Zadelhoff G and van der Stelt M Oxygenation of Anandamide by Lipoxygenases. 2016 Methods Mol. Biol. pmid:27245907
Fezza F et al. Methods to assay anandamide hydrolysis and transport in synaptosomes. 2006 Methods Mol. Med. pmid:16506407
Chen P et al. Induction of cyclooxygenase-2 by anandamide in cerebral microvascular endothelium. 2005 Microvasc. Res. pmid:15797258
Bari M et al. New insights into endocannabinoid degradation and its therapeutic potential. 2006 Mini Rev Med Chem pmid:16515464
Marco EM and Viveros MP The critical role of the endocannabinoid system in emotional homeostasis: avoiding excess and deficiencies. 2009 Mini Rev Med Chem pmid:19929814
Lu W et al. Voltage-independent sodium channels emerge for an expression of activity-induced spontaneous spikes in GABAergic neurons. 2014 Mol Brain pmid:24886791
Ma C et al. Anti-carcinogenic activity of anandamide on human glioma in vitro and in vivo. 2016 Mol Med Rep pmid:26707955
Gurwitz D and Kloog Y Do endogenous cannabinoids contribute to HIV-mediated immune failure? 1998 Mol Med Today pmid:9612798
Banni S and Di Marzo V Effect of dietary fat on endocannabinoids and related mediators: consequences on energy homeostasis, inflammation and mood. 2010 Mol Nutr Food Res pmid:20013888
Rajaraman G et al. G protein coupled receptor 18: A potential role for endocannabinoid signaling in metabolic dysfunction. 2016 Mol Nutr Food Res pmid:26337420
Guasti L et al. Minocycline treatment inhibits microglial activation and alters spinal levels of endocannabinoids in a rat model of neuropathic pain. 2009 Mol Pain pmid:19570201
Woo DH et al. Direct activation of transient receptor potential vanilloid 1(TRPV1) by diacylglycerol (DAG). 2008 Mol Pain pmid:18826653
Kuc C et al. Arachidonoyl ethanolamide (AEA)-induced apoptosis is mediated by J-series prostaglandins and is enhanced by fatty acid amide hydrolase (FAAH) blockade. 2012 Mol. Carcinog. pmid:21432910
Van Dross RT Metabolism of anandamide by COX-2 is necessary for endocannabinoid-induced cell death in tumorigenic keratinocytes. 2009 Mol. Carcinog. pmid:19148897
Triggle CR et al. The endothelium in health and disease: a discussion of the contribution of non-nitric oxide endothelium-derived vasoactive mediators to vascular homeostasis in normal vessels and in type II diabetes. 2004 Mol. Cell. Biochem. pmid:15524164
Qureshi J et al. Identification and characterization of a novel synthetic cannabinoid CP 55,940 binder in rat brain cytosol. 1998 Mol. Cell. Biochem. pmid:9562238
González-Mariscal I et al. Blockade of cannabinoid 1 receptor improves GLP-1R mediated insulin secretion in mice. 2016 Mol. Cell. Endocrinol. pmid:26724516
Battista N et al. The role of endocannabinoids in gonadal function and fertility along the evolutionary axis. 2012 Mol. Cell. Endocrinol. pmid:22305972
Cavuoto P et al. Effects of cannabinoid receptors on skeletal muscle oxidative pathways. 2007 Mol. Cell. Endocrinol. pmid:17270342
Oláh M et al. The role of endocannabinoids in the regulation of luteinizing hormone and prolactin release. Differences between the effects of AEA and 2AG. 2008 Mol. Cell. Endocrinol. pmid:18308464
Migliarini B and Carnevali O Anandamide modulates growth and lipid metabolism in the zebrafish Danio rerio. 2008 Mol. Cell. Endocrinol. pmid:18342434
Catanzaro G et al. Effect of capacitation on the endocannabinoid system of mouse sperm. 2011 Mol. Cell. Endocrinol. pmid:21723369
Musella A et al. TRPV1 channels facilitate glutamate transmission in the striatum. 2009 Mol. Cell. Neurosci. pmid:18930149
Fezza F et al. Distinct modulation of the endocannabinoid system upon kainic acid-induced in vivo seizures and in vitro epileptiform bursting. 2014 Mol. Cell. Neurosci. pmid:25064144
Krishnan G and Chatterjee N Endocannabinoids affect innate immunity of Muller glia during HIV-1 Tat cytotoxicity. 2014 Mol. Cell. Neurosci. pmid:24418364
Brighton PJ et al. Characterization of anandamide-stimulated cannabinoid receptor signaling in human ULTR myometrial smooth muscle cells. 2009 Mol. Endocrinol. pmid:19477951
Maccarrone M et al. Low fatty acid amide hydrolase and high anandamide levels are associated with failure to achieve an ongoing pregnancy after IVF and embryo transfer. 2002 Mol. Hum. Reprod. pmid:11818522