| MeSH term | MeSH ID | Detail |
|---|---|---|
| Ventricular Fibrillation | D014693 | 16 associated lipids |
| Fever | D005334 | 35 associated lipids |
| Bronchial Spasm | D001986 | 18 associated lipids |
| Morphine Dependence | D009021 | 9 associated lipids |
| Shock, Septic | D012772 | 11 associated lipids |
| Cough | D003371 | 19 associated lipids |
| Encephalomyelitis, Autoimmune, Experimental | D004681 | 26 associated lipids |
| Catalepsy | D002375 | 30 associated lipids |
| Migraine Disorders | D008881 | 11 associated lipids |
| Cardiomyopathy, Dilated | D002311 | 15 associated lipids |
Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Oka S et al. | Depolarization-induced rapid generation of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, in rat brain synaptosomes. | 2007 | J. Biochem. | pmid:17339228 |
| D'Argenio G et al. | Overactivity of the intestinal endocannabinoid system in celiac disease and in methotrexate-treated rats. | 2007 | J. Mol. Med. | pmid:17396241 |
| Holt S et al. | Inhibition of fatty acid amide hydrolase, a key endocannabinoid metabolizing enzyme, by analogues of ibuprofen and indomethacin. | 2007 | Eur. J. Pharmacol. | pmid:17397826 |
| Mahler SV et al. | Endocannabinoid hedonic hotspot for sensory pleasure: anandamide in nucleus accumbens shell enhances 'liking' of a sweet reward. | 2007 | Neuropsychopharmacology | pmid:17406653 |
| Kopczyńska B | The contribution of VR1 and CB1 receptors and the role of the afferent vagal pathway in modelling of cardio-respiratory effects of anandamide in rats. | 2007 | Life Sci. | pmid:17379256 |
| Ferrer B et al. | Regulation of brain anandamide by acute administration of ethanol. | 2007 | Biochem. J. | pmid:17302558 |
| Naidu PS et al. | Evaluation of fatty acid amide hydrolase inhibition in murine models of emotionality. | 2007 | Psychopharmacology (Berl.) | pmid:17279376 |
| Sun Y et al. | Cannabinoid activation of PPAR alpha; a novel neuroprotective mechanism. | 2007 | Br. J. Pharmacol. | pmid:17906680 |
| Rubio M et al. | Short-term exposure to alcohol in rats affects brain levels of anandamide, other N-acylethanolamines and 2-arachidonoyl-glycerol. | 2007 | Neurosci. Lett. | pmid:17574742 |
| Ryberg E et al. | The orphan receptor GPR55 is a novel cannabinoid receptor. | 2007 | Br. J. Pharmacol. | pmid:17876302 |
| Mulè F et al. | Evidence for a modulatory role of cannabinoids on the excitatory NANC neurotransmission in mouse colon. | 2007 | Pharmacol. Res. | pmid:17574859 |
| Karsak M et al. | Attenuation of allergic contact dermatitis through the endocannabinoid system. | 2007 | Science | pmid:17556587 |
| Bátkai S et al. | Endocannabinoids acting at CB1 receptors mediate the cardiac contractile dysfunction in vivo in cirrhotic rats. | 2007 | Am. J. Physiol. Heart Circ. Physiol. | pmid:17557913 |
| Williams J et al. | Quantitative method for the profiling of the endocannabinoid metabolome by LC-atmospheric pressure chemical ionization-MS. | 2007 | Anal. Chem. | pmid:17600384 |
| Esposito G et al. | Opposing control of cannabinoid receptor stimulation on amyloid-beta-induced reactive gliosis: in vitro and in vivo evidence. | 2007 | J. Pharmacol. Exp. Ther. | pmid:17545311 |
| Karanian DA et al. | Endocannabinoid enhancement protects against kainic acid-induced seizures and associated brain damage. | 2007 | J. Pharmacol. Exp. Ther. | pmid:17545313 |
| Velenovská M and Fisar Z | Effect of cannabinoids on platelet serotonin uptake. | 2007 | Addict Biol | pmid:17508987 |
| Michalski CW et al. | Cannabinoids ameliorate pain and reduce disease pathology in cerulein-induced acute pancreatitis. | 2007 | Gastroenterology | pmid:17484889 |
| Ghasemi M et al. | Role of the nitric oxide pathway and the endocannabinoid system in neurogenic relaxation of corpus cavernosum from biliary cirrhotic rats. | 2007 | Br. J. Pharmacol. | pmid:17486141 |
| Borsani E et al. | AM404 decreases Fos-immunoreactivity in the spinal cord in a model of inflammatory pain. | 2007 | Brain Res. | pmid:17459353 |
| Sit SY et al. | Novel inhibitors of fatty acid amide hydrolase. | 2007 | Bioorg. Med. Chem. Lett. | pmid:17459705 |
| Lory P and Chemin J | Towards the discovery of novel T-type calcium channel blockers. | 2007 | Expert Opin. Ther. Targets | pmid:17465728 |
| Ryan D et al. | Interactions of cannabidiol with endocannabinoid signalling in hippocampal tissue. | 2007 | Eur. J. Neurosci. | pmid:17419758 |
| Gonthier MP et al. | Identification of endocannabinoids and related compounds in human fat cells. | 2007 | Obesity (Silver Spring) | pmid:17426318 |
| Raduner S et al. | Self-assembling cannabinomimetics: supramolecular structures of N-alkyl amides. | 2007 | J. Nat. Prod. | pmid:17497806 |
| Wang Y and Wang DH | Neural control of blood pressure: focusing on capsaicin-sensitive sensory nerves. | 2007 | Cardiovasc Hematol Disord Drug Targets | pmid:17346127 |
| Basavarajappa BS | Critical enzymes involved in endocannabinoid metabolism. | 2007 | Protein Pept. Lett. | pmid:17346227 |
| Jia Y and Lee LY | Role of TRPV receptors in respiratory diseases. | 2007 | Biochim. Biophys. Acta | pmid:17346945 |
| Solinas M et al. | Nicotinic facilitation of delta9-tetrahydrocannabinol discrimination involves endogenous anandamide. | 2007 | J. Pharmacol. Exp. Ther. | pmid:17351107 |
| Centonze D et al. | The endocannabinoid system is dysregulated in multiple sclerosis and in experimental autoimmune encephalomyelitis. | 2007 | Brain | pmid:17626034 |
| Spivak CE et al. | The endocannabinoid anandamide inhibits the function of alpha4beta2 nicotinic acetylcholine receptors. | 2007 | Mol. Pharmacol. | pmid:17628012 |
| Béquet F et al. | CB1 receptor-mediated control of the release of endocannabinoids (as assessed by microdialysis coupled with LC/MS) in the rat hypothalamus. | 2007 | Eur. J. Neurosci. | pmid:18052990 |
| Rettori V et al. | Endocannabinoids in TNF-alpha and ethanol actions. | 2007 | Neuroimmunomodulation | pmid:18073513 |
| Akerman S et al. | Cannabinoid (CB1) receptor activation inhibits trigeminovascular neurons. | 2007 | J. Pharmacol. Exp. Ther. | pmid:17018694 |
| Shimozawa N et al. | Estrogen and isoflavone attenuate stress-induced gastric mucosal injury by inhibiting decreases in gastric tissue levels of CGRP in ovariectomized rats. | 2007 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:17023553 |
| Yang YY et al. | Role of Ca2+-dependent potassium channels in in vitro anandamide-mediated mesenteric vasorelaxation in rats with biliary cirrhosis. | 2007 | Liver Int. | pmid:17845532 |
| Rossi G et al. | Follicle-stimulating hormone activates fatty acid amide hydrolase by protein kinase A and aromatase-dependent pathways in mouse primary Sertoli cells. | 2007 | Endocrinology | pmid:17110429 |
| Cross-Mellor SK et al. | Effects of the FAAH inhibitor, URB597, and anandamide on lithium-induced taste reactivity responses: a measure of nausea in the rat. | 2007 | Psychopharmacology (Berl.) | pmid:17111174 |
| Ronco AM et al. | Anandamide inhibits endothelin-1 production by human cultured endothelial cells: a new vascular action of this endocannabinoid. | 2007 | Pharmacology | pmid:17114903 |
| Ho WS and Randall MD | Endothelium-dependent metabolism by endocannabinoid hydrolases and cyclooxygenases limits vasorelaxation to anandamide and 2-arachidonoylglycerol. | 2007 | Br. J. Pharmacol. | pmid:17245358 |
| Wheal AJ et al. | Effects of chronic nitric oxide synthase inhibition on the cardiovascular responses to cannabinoids in vivo and in vitro. | 2007 | Br. J. Pharmacol. | pmid:17245361 |
| Harada N and Okajima K | Effect of topical application of capsaicin and its related compounds on dermal insulin-like growth factor-I levels in mice and on facial skin elasticity in humans. | 2007 | Growth Horm. IGF Res. | pmid:17307377 |
| Romero FA et al. | Potent and selective alpha-ketoheterocycle-based inhibitors of the anandamide and oleamide catabolizing enzyme, fatty acid amide hydrolase. | 2007 | J. Med. Chem. | pmid:17279740 |
| Wang Y et al. | Endocannabinoid regulates blood pressure via activation of the transient receptor potential vanilloid type 1 in Wistar rats fed a high-salt diet. | 2007 | J. Pharmacol. Exp. Ther. | pmid:17308041 |
| Snider NT et al. | Anandamide metabolism by human liver and kidney microsomal cytochrome p450 enzymes to form hydroxyeicosatetraenoic and epoxyeicosatrienoic acid ethanolamides. | 2007 | J. Pharmacol. Exp. Ther. | pmid:17272674 |
| Matta JA et al. | TRPV1 is a novel target for omega-3 polyunsaturated fatty acids. | 2007 | J. Physiol. (Lond.) | pmid:17038422 |
| Solinas M et al. | The endogenous cannabinoid anandamide produces delta-9-tetrahydrocannabinol-like discriminative and neurochemical effects that are enhanced by inhibition of fatty acid amide hydrolase but not by inhibition of anandamide transport. | 2007 | J. Pharmacol. Exp. Ther. | pmid:17210800 |
| Hsu SS et al. | Anandamide-induced Ca2+ elevation leading to p38 MAPK phosphorylation and subsequent cell death via apoptosis in human osteosarcoma cells. | 2007 | Toxicology | pmid:17222495 |
| Harada N and Okajima K | Inhibition of neutrophil activation by lafutidine, an H2-receptor antagonist, through enhancement of sensory neuron activation contributes to the reduction of stress-induced gastric mucosal injury in rats. | 2007 | Dig. Dis. Sci. | pmid:17211693 |
| Pisanti S et al. | Antiangiogenic activity of the endocannabinoid anandamide: correlation to its tumor-suppressor efficacy. | 2007 | J. Cell. Physiol. | pmid:17192847 |
| Ekins S et al. | Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors. | 2007 | Drug Metab. Dispos. | pmid:17194716 |
| Schreiber D et al. | Determination of anandamide and other fatty acyl ethanolamides in human serum by electrospray tandem mass spectrometry. | 2007 | Anal. Biochem. | pmid:17196922 |
| Kreutz S et al. | Cannabinoids and neuronal damage: differential effects of THC, AEA and 2-AG on activated microglial cells and degenerating neurons in excitotoxically lesioned rat organotypic hippocampal slice cultures. | 2007 | Exp. Neurol. | pmid:17010339 |
| Degenhardt BF et al. | Role of osteopathic manipulative treatment in altering pain biomarkers: a pilot study. | 2007 | J Am Osteopath Assoc | pmid:17908831 |
| Xu H et al. | Functional effects of nonsynonymous polymorphisms in the human TRPV1 gene. | 2007 | Am. J. Physiol. Renal Physiol. | pmid:17913835 |
| Athanasiou A et al. | Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. | 2007 | Biochem. Biophys. Res. Commun. | pmid:17931597 |
| Morgese MG et al. | Anti-dyskinetic effects of cannabinoids in a rat model of Parkinson's disease: role of CB(1) and TRPV1 receptors. | 2007 | Exp. Neurol. | pmid:17900568 |
| Battista N et al. | The endocannabinoid system in neurodegeneration. | 2006 Sep-Dec | Ital. J. Biochem. | pmid:17274532 |
| Lynch DL and Reggio PH | Cannabinoid CB1 receptor recognition of endocannabinoids via the lipid bilayer: molecular dynamics simulations of CB1 transmembrane helix 6 and anandamide in a phospholipid bilayer. | 2006 Jul-Aug | J. Comput. Aided Mol. Des. | pmid:17106765 |
| Dickason-Chesterfield AK et al. | Pharmacological characterization of endocannabinoid transport and fatty acid amide hydrolase inhibitors. | 2006 Jul-Aug | Cell. Mol. Neurobiol. | pmid:16736384 |
| Millns PJ et al. | Effects of inhibition of fatty acid amide hydrolase vs. the anandamide membrane transporter on TRPV1-mediated calcium responses in adult DRG neurons; the role of CB receptors. | 2006 | Eur. J. Neurosci. | pmid:17229097 |
| Liu J et al. | A biosynthetic pathway for anandamide. | 2006 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16938887 |
| Mechoulam R et al. | Endocannabinoids, feeding and suckling--from our perspective. | 2006 | Int J Obes (Lond) | pmid:16570101 |
| Matias I et al. | Endogenous cannabinoids in the brain and peripheral tissues: regulation of their levels and control of food intake. | 2006 | Int J Obes (Lond) | pmid:16570107 |
| Schiano Moriello A et al. | Development of the first potential covalent inhibitors of anandamide cellular uptake. | 2006 | J. Med. Chem. | pmid:16570928 |
| Appendino G et al. | Oxyhomologues of anandamide and related endolipids: chemoselective synthesis and biological activity. | 2006 | J. Med. Chem. | pmid:16570929 |
| Chang L et al. | Inhibition of fatty acid amide hydrolase produces analgesia by multiple mechanisms. | 2006 | Br. J. Pharmacol. | pmid:16501580 |
| Fezza F et al. | Methods to assay anandamide hydrolysis and transport in synaptosomes. | 2006 | Methods Mol. Med. | pmid:16506407 |
| Kaczocha M et al. | Anandamide uptake is consistent with rate-limited diffusion and is regulated by the degree of its hydrolysis by fatty acid amide hydrolase. | 2006 | J. Biol. Chem. | pmid:16461355 |
| Waku K | [Endogenous cannabinoid receptor ligands--anandamide and 2-arachidonoylglycerol]. | 2006 | Yakugaku Zasshi | pmid:16462096 |
| Petersen G et al. | Intestinal levels of anandamide and oleoylethanolamide in food-deprived rats are regulated through their precursors. | 2006 | Biochim. Biophys. Acta | pmid:16478679 |
| Guindon J et al. | Local interactions between anandamide, an endocannabinoid, and ibuprofen, a nonsteroidal anti-inflammatory drug, in acute and inflammatory pain. | 2006 | Pain | pmid:16480822 |
| Guindon J et al. | Synergistic antinociceptive effects of anandamide, an endocannabinoid, and nonsteroidal anti-inflammatory drugs in peripheral tissue: a role for endogenous fatty-acid ethanolamides? | 2006 | Eur. J. Pharmacol. | pmid:17027744 |
| Prestifilippo JP et al. | Inhibition of salivary secretion by activation of cannabinoid receptors. | 2006 | Exp. Biol. Med. (Maywood) | pmid:16946411 |
| Spoto B et al. | Human adipose tissue binds and metabolizes the endocannabinoids anandamide and 2-arachidonoylglycerol. | 2006 | Biochimie | pmid:16949718 |
| Vlachou S et al. | Effects of endocannabinoid neurotransmission modulators on brain stimulation reward. | 2006 | Psychopharmacology (Berl.) | pmid:16953388 |
| Mulder AM and Cravatt BF | Endocannabinoid metabolism in the absence of fatty acid amide hydrolase (FAAH): discovery of phosphorylcholine derivatives of N-acyl ethanolamines. | 2006 | Biochemistry | pmid:16981687 |
| Hong Z et al. | Role of store-operated calcium channels and calcium sensitization in normoxic contraction of the ductus arteriosus. | 2006 | Circulation | pmid:16982938 |
| Stefano GB and Salamon EJ | Nitric oxide and anandamide in OMT research. | 2006 | J Am Osteopath Assoc | pmid:17122026 |
| Lambert RC et al. | Modulation of neuronal T-type calcium channels. | 2006 | CNS Neurol Disord Drug Targets | pmid:17168746 |
| Giuliano M et al. | Anandamide-induced apoptosis in Chang liver cells involves ceramide and JNK/AP-1 pathway. | 2006 | Int. J. Mol. Med. | pmid:16596265 |
| Di Marzo M et al. | Synthesis, conformational analysis and CB1 binding affinity of hairpin-like anandamide pseudopeptide mimetics. | 2006 | J. Pept. Sci. | pmid:16534762 |
| Cobellis G et al. | Endocannabinoid system in frog and rodent testis: type-1 cannabinoid receptor and fatty acid amide hydrolase activity in male germ cells. | 2006 | Biol. Reprod. | pmid:16611862 |
| Solinas M et al. | Anandamide administration alone and after inhibition of fatty acid amide hydrolase (FAAH) increases dopamine levels in the nucleus accumbens shell in rats. | 2006 | J. Neurochem. | pmid:16805835 |
| Vinod KY et al. | Effect of chronic ethanol exposure and its withdrawal on the endocannabinoid system. | 2006 | Neurochem. Int. | pmid:16822589 |
| Ghasemi M et al. | Effect of anandamide on nonadrenergic noncholinergic-mediated relaxation of rat corpus cavernosum. | 2006 | Eur. J. Pharmacol. | pmid:16824514 |
| Wagner JA et al. | 2-Arachidonylglycerol acting on CB1 cannabinoid receptors mediates delayed cardioprotection induced by nitric oxide in rat isolated hearts. | 2006 | J. Cardiovasc. Pharmacol. | pmid:16775503 |
| Bonechi C et al. | Nuclear magnetic resonance for studying recognition processes between anandamide and cannabinoid receptors. | 2006 | Eur J Med Chem | pmid:16837109 |
| Costa B et al. | AM404, an inhibitor of anandamide uptake, prevents pain behaviour and modulates cytokine and apoptotic pathways in a rat model of neuropathic pain. | 2006 | Br. J. Pharmacol. | pmid:16770320 |
| Felder CC et al. | Cannabinoids biology: the search for new therapeutic targets. | 2006 | Mol. Interv. | pmid:16809476 |
| Li J and Wang DH | Differential mechanisms mediating depressor and diuretic effects of anandamide. | 2006 | J. Hypertens. | pmid:17053550 |
| Krishtal O et al. | The agonists for nociceptors are ubiquitous, but the modulators are specific: P2X receptors in the sensory neurons are modulated by cannabinoids. | 2006 | Pflugers Arch. | pmid:16741755 |
| Tzavara ET et al. | Endocannabinoids activate transient receptor potential vanilloid 1 receptors to reduce hyperdopaminergia-related hyperactivity: therapeutic implications. | 2006 | Biol. Psychiatry | pmid:16199010 |
| Schmidt A et al. | Determination of the endocannabinoid anandamide in human plasma by high-performance liquid chromatography. | 2006 | Biomed. Chromatogr. | pmid:16189813 |
| Bai X et al. | TASK channel expression in human placenta and cytotrophoblast cells. | 2006 | J. Soc. Gynecol. Investig. | pmid:16378911 |
| Hejazi N et al. | Delta9-tetrahydrocannabinol and endogenous cannabinoid anandamide directly potentiate the function of glycine receptors. | 2006 | Mol. Pharmacol. | pmid:16332990 |
| Suplita RL et al. | Endocannabinoids at the spinal level regulate, but do not mediate, nonopioid stress-induced analgesia. | 2006 | Neuropharmacology | pmid:16316669 |
| Avelino A and Cruz F | TRPV1 (vanilloid receptor) in the urinary tract: expression, function and clinical applications. | 2006 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:16721555 |
| Ligresti A et al. | New potent and selective inhibitors of anandamide reuptake with antispastic activity in a mouse model of multiple sclerosis. | 2006 | Br. J. Pharmacol. | pmid:16284631 |
| Bir LS and Ercan S | Effects of intrathecal anandamide on somatosensory evoked responses in rats. | 2006 | Exp. Neurol. | pmid:16289169 |