| MeSH term | MeSH ID | Detail |
|---|---|---|
| Ventricular Fibrillation | D014693 | 16 associated lipids |
| Fever | D005334 | 35 associated lipids |
| Bronchial Spasm | D001986 | 18 associated lipids |
| Morphine Dependence | D009021 | 9 associated lipids |
| Shock, Septic | D012772 | 11 associated lipids |
| Cough | D003371 | 19 associated lipids |
| Encephalomyelitis, Autoimmune, Experimental | D004681 | 26 associated lipids |
| Catalepsy | D002375 | 30 associated lipids |
| Migraine Disorders | D008881 | 11 associated lipids |
| Cardiomyopathy, Dilated | D002311 | 15 associated lipids |
Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Millns PJ et al. | Effects of inhibition of fatty acid amide hydrolase vs. the anandamide membrane transporter on TRPV1-mediated calcium responses in adult DRG neurons; the role of CB receptors. | 2006 | Eur. J. Neurosci. | pmid:17229097 |
| Mechoulam R et al. | Endocannabinoids, feeding and suckling--from our perspective. | 2006 | Int J Obes (Lond) | pmid:16570101 |
| Matias I et al. | Endogenous cannabinoids in the brain and peripheral tissues: regulation of their levels and control of food intake. | 2006 | Int J Obes (Lond) | pmid:16570107 |
| Schiano Moriello A et al. | Development of the first potential covalent inhibitors of anandamide cellular uptake. | 2006 | J. Med. Chem. | pmid:16570928 |
| Appendino G et al. | Oxyhomologues of anandamide and related endolipids: chemoselective synthesis and biological activity. | 2006 | J. Med. Chem. | pmid:16570929 |
| Chang L et al. | Inhibition of fatty acid amide hydrolase produces analgesia by multiple mechanisms. | 2006 | Br. J. Pharmacol. | pmid:16501580 |
| Fezza F et al. | Methods to assay anandamide hydrolysis and transport in synaptosomes. | 2006 | Methods Mol. Med. | pmid:16506407 |
| Kaczocha M et al. | Anandamide uptake is consistent with rate-limited diffusion and is regulated by the degree of its hydrolysis by fatty acid amide hydrolase. | 2006 | J. Biol. Chem. | pmid:16461355 |
| Waku K | [Endogenous cannabinoid receptor ligands--anandamide and 2-arachidonoylglycerol]. | 2006 | Yakugaku Zasshi | pmid:16462096 |
| Petersen G et al. | Intestinal levels of anandamide and oleoylethanolamide in food-deprived rats are regulated through their precursors. | 2006 | Biochim. Biophys. Acta | pmid:16478679 |
| Guindon J et al. | Local interactions between anandamide, an endocannabinoid, and ibuprofen, a nonsteroidal anti-inflammatory drug, in acute and inflammatory pain. | 2006 | Pain | pmid:16480822 |
| Busch L et al. | Effects of castration on cannabinoid cb receptor expression and on the biological actions of cannabinoid in the parotid gland. | 2006 | Clin. Exp. Pharmacol. Physiol. | pmid:16487271 |
| Schelling G et al. | Effects of general anesthesia on anandamide blood levels in humans. | 2006 | Anesthesiology | pmid:16436846 |
| Guindon J and Beaulieu P | Antihyperalgesic effects of local injections of anandamide, ibuprofen, rofecoxib and their combinations in a model of neuropathic pain. | 2006 | Neuropharmacology | pmid:16442133 |
| Bermúdez-Siva FJ et al. | Activation of cannabinoid CB1 receptors induces glucose intolerance in rats. | 2006 | Eur. J. Pharmacol. | pmid:16423347 |
| Guagnini F et al. | Neural contractions in colonic strips from patients with diverticular disease: role of endocannabinoids and substance P. | 2006 | Gut | pmid:16423891 |
| Meuth SG et al. | The contribution of TWIK-related acid-sensitive K+-containing channels to the function of dorsal lateral geniculate thalamocortical relay neurons. | 2006 | Mol. Pharmacol. | pmid:16424077 |
| Marx J | Drug development. Drugs inspired by a drug. | 2006 | Science | pmid:16424309 |
| Cupini LM et al. | Biochemical changes in endocannabinoid system are expressed in platelets of female but not male migraineurs. | 2006 | Cephalalgia | pmid:16472333 |
| GarcÃa Mdel C et al. | Role of CGRP and GABA in the hypotensive effect of intrathecally administered anandamide to anesthetized rats. | 2006 | Eur. J. Pharmacol. | pmid:16472800 |
| Guindon J et al. | Synergistic antinociceptive effects of anandamide, an endocannabinoid, and nonsteroidal anti-inflammatory drugs in peripheral tissue: a role for endogenous fatty-acid ethanolamides? | 2006 | Eur. J. Pharmacol. | pmid:17027744 |
| Prestifilippo JP et al. | Inhibition of salivary secretion by activation of cannabinoid receptors. | 2006 | Exp. Biol. Med. (Maywood) | pmid:16946411 |
| Spoto B et al. | Human adipose tissue binds and metabolizes the endocannabinoids anandamide and 2-arachidonoylglycerol. | 2006 | Biochimie | pmid:16949718 |
| Vlachou S et al. | Effects of endocannabinoid neurotransmission modulators on brain stimulation reward. | 2006 | Psychopharmacology (Berl.) | pmid:16953388 |
| Mulder AM and Cravatt BF | Endocannabinoid metabolism in the absence of fatty acid amide hydrolase (FAAH): discovery of phosphorylcholine derivatives of N-acyl ethanolamines. | 2006 | Biochemistry | pmid:16981687 |
| Hong Z et al. | Role of store-operated calcium channels and calcium sensitization in normoxic contraction of the ductus arteriosus. | 2006 | Circulation | pmid:16982938 |
| Stefano GB and Salamon EJ | Nitric oxide and anandamide in OMT research. | 2006 | J Am Osteopath Assoc | pmid:17122026 |
| Lambert RC et al. | Modulation of neuronal T-type calcium channels. | 2006 | CNS Neurol Disord Drug Targets | pmid:17168746 |
| Fowler CJ | The cannabinoid system and its pharmacological manipulation--a review, with emphasis upon the uptake and hydrolysis of anandamide. | 2006 | Fundam Clin Pharmacol | pmid:17109648 |
| De Lago E et al. | Acyl-based anandamide uptake inhibitors cause rapid toxicity to C6 glioma cells at pharmacologically relevant concentrations. | 2006 | J. Neurochem. | pmid:16899063 |
| Laezza C et al. | Anandamide inhibits Cdk2 and activates Chk1 leading to cell cycle arrest in human breast cancer cells. | 2006 | FEBS Lett. | pmid:17055492 |
| Giuliano M et al. | Anandamide-induced apoptosis in Chang liver cells involves ceramide and JNK/AP-1 pathway. | 2006 | Int. J. Mol. Med. | pmid:16596265 |
| Di Marzo M et al. | Synthesis, conformational analysis and CB1 binding affinity of hairpin-like anandamide pseudopeptide mimetics. | 2006 | J. Pept. Sci. | pmid:16534762 |
| Cobellis G et al. | Endocannabinoid system in frog and rodent testis: type-1 cannabinoid receptor and fatty acid amide hydrolase activity in male germ cells. | 2006 | Biol. Reprod. | pmid:16611862 |
| Solinas M et al. | Anandamide administration alone and after inhibition of fatty acid amide hydrolase (FAAH) increases dopamine levels in the nucleus accumbens shell in rats. | 2006 | J. Neurochem. | pmid:16805835 |
| Vinod KY et al. | Effect of chronic ethanol exposure and its withdrawal on the endocannabinoid system. | 2006 | Neurochem. Int. | pmid:16822589 |
| Ghasemi M et al. | Effect of anandamide on nonadrenergic noncholinergic-mediated relaxation of rat corpus cavernosum. | 2006 | Eur. J. Pharmacol. | pmid:16824514 |
| Wagner JA et al. | 2-Arachidonylglycerol acting on CB1 cannabinoid receptors mediates delayed cardioprotection induced by nitric oxide in rat isolated hearts. | 2006 | J. Cardiovasc. Pharmacol. | pmid:16775503 |
| Bonechi C et al. | Nuclear magnetic resonance for studying recognition processes between anandamide and cannabinoid receptors. | 2006 | Eur J Med Chem | pmid:16837109 |
| Costa B et al. | AM404, an inhibitor of anandamide uptake, prevents pain behaviour and modulates cytokine and apoptotic pathways in a rat model of neuropathic pain. | 2006 | Br. J. Pharmacol. | pmid:16770320 |
| Felder CC et al. | Cannabinoids biology: the search for new therapeutic targets. | 2006 | Mol. Interv. | pmid:16809476 |
| Yeh JH et al. | Effect of anandamide on cytosolic Ca(2+) levels and proliferation in canine renal tubular cells. | 2006 | Basic Clin. Pharmacol. Toxicol. | pmid:16623868 |
| Laviolette SR and Grace AA | The roles of cannabinoid and dopamine receptor systems in neural emotional learning circuits: implications for schizophrenia and addiction. | 2006 | Cell. Mol. Life Sci. | pmid:16699809 |
| Balas L et al. | Synthesis of a potential photoactivatable anandamide analog. | 2006 | Bioorg. Med. Chem. Lett. | pmid:16682198 |
| Shouman B et al. | Endocannabinoids potently protect the newborn brain against AMPA-kainate receptor-mediated excitotoxic damage. | 2006 | Br. J. Pharmacol. | pmid:16682966 |
| Zaniewska M et al. | Evaluation of the role of nicotinic acetylcholine receptor subtypes and cannabinoid system in the discriminative stimulus effects of nicotine in rats. | 2006 | Eur. J. Pharmacol. | pmid:16730696 |
| Harada N et al. | Antithrombin reduces endotoxin-induced hypotension by enhancing pulmonary sensory neuron activation in rats. | 2006 | Thromb. Haemost. | pmid:16732381 |
| van der Stelt M et al. | Endocannabinoids and beta-amyloid-induced neurotoxicity in vivo: effect of pharmacological elevation of endocannabinoid levels. | 2006 | Cell. Mol. Life Sci. | pmid:16732431 |
| Fisyunov A et al. | Cannabinoids modulate the P-type high-voltage-activated calcium currents in purkinje neurons. | 2006 | J. Neurophysiol. | pmid:16738209 |
| Vogeser M et al. | Release of anandamide from blood cells. | 2006 | Clin. Chem. Lab. Med. | pmid:16599845 |
| Li J and Wang DH | Differential mechanisms mediating depressor and diuretic effects of anandamide. | 2006 | J. Hypertens. | pmid:17053550 |
| Krishtal O et al. | The agonists for nociceptors are ubiquitous, but the modulators are specific: P2X receptors in the sensory neurons are modulated by cannabinoids. | 2006 | Pflugers Arch. | pmid:16741755 |
| Wang Y et al. | A novel scintillation proximity assay for fatty acid amide hydrolase compatible with inhibitor screening. | 2006 | Anal. Biochem. | pmid:16707086 |
| Schmidt A et al. | Determination of the endocannabinoid anandamide in human plasma by high-performance liquid chromatography. | 2006 | Biomed. Chromatogr. | pmid:16189813 |
| Wiles AL et al. | N-Arachidonyl-glycine inhibits the glycine transporter, GLYT2a. | 2006 | J. Neurochem. | pmid:16899062 |
| Bai X et al. | TASK channel expression in human placenta and cytotrophoblast cells. | 2006 | J. Soc. Gynecol. Investig. | pmid:16378911 |
| Hejazi N et al. | Delta9-tetrahydrocannabinol and endogenous cannabinoid anandamide directly potentiate the function of glycine receptors. | 2006 | Mol. Pharmacol. | pmid:16332990 |
| Bojesen IN and Hansen HS | Effect of an unstirred layer on the membrane permeability of anandamide. | 2006 | J. Lipid Res. | pmid:16365480 |
| Dembiński A et al. | Cannabinoids in acute gastric damage and pancreatitis. | 2006 | J. Physiol. Pharmacol. | pmid:17218765 |
| D'Argenio G et al. | Up-regulation of anandamide levels as an endogenous mechanism and a pharmacological strategy to limit colon inflammation. | 2006 | FASEB J. | pmid:16403786 |
| Nakajima Y et al. | Endocannabinoid, anandamide in gingival tissue regulates the periodontal inflammation through NF-kappaB pathway inhibition. | 2006 | FEBS Lett. | pmid:16406050 |
| Suplita RL et al. | Endocannabinoids at the spinal level regulate, but do not mediate, nonopioid stress-induced analgesia. | 2006 | Neuropharmacology | pmid:16316669 |
| Avelino A and Cruz F | TRPV1 (vanilloid receptor) in the urinary tract: expression, function and clinical applications. | 2006 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:16721555 |
| Murillo-Rodriguez E et al. | Diurnal variation of arachidonoylethanolamine, palmitoylethanolamide and oleoylethanolamide in the brain of the rat. | 2006 | Life Sci. | pmid:16434061 |
| Juan-Picó P et al. | Cannabinoid receptors regulate Ca(2+) signals and insulin secretion in pancreatic beta-cell. | 2006 | Cell Calcium | pmid:16321437 |
| Cannizzaro C et al. | Presynaptic effects of anandamide and WIN55,212-2 on glutamatergic nerve endings isolated from rat hippocampus. | 2006 | Neurochem. Int. | pmid:16325966 |
| Lizanecz E et al. | Phosphorylation-dependent desensitization by anandamide of vanilloid receptor-1 (TRPV1) function in rat skeletal muscle arterioles and in Chinese hamster ovary cells expressing TRPV1. | 2006 | Mol. Pharmacol. | pmid:16338989 |
| Grimaldi C et al. | Anandamide inhibits adhesion and migration of breast cancer cells. | 2006 | Exp. Cell Res. | pmid:16343481 |
| de Lago E et al. | UCM707, an inhibitor of the anandamide uptake, behaves as a symptom control agent in models of Huntington's disease and multiple sclerosis, but fails to delay/arrest the progression of different motor-related disorders. | 2006 | Eur Neuropsychopharmacol | pmid:16006105 |
| Ligresti A et al. | New potent and selective inhibitors of anandamide reuptake with antispastic activity in a mouse model of multiple sclerosis. | 2006 | Br. J. Pharmacol. | pmid:16284631 |
| Bir LS and Ercan S | Effects of intrathecal anandamide on somatosensory evoked responses in rats. | 2006 | Exp. Neurol. | pmid:16289169 |
| Urbani P et al. | New metabolically stable fatty acid amide ligands of cannabinoid receptors: Synthesis and receptor affinity studies. | 2006 | Bioorg. Med. Chem. Lett. | pmid:16213718 |
| Glaser ST et al. | Ex vivo imaging of fatty acid amide hydrolase activity and its inhibition in the mouse brain. | 2006 | J. Pharmacol. Exp. Ther. | pmid:16278311 |
| Malfitano AM et al. | Arvanil inhibits T lymphocyte activation and ameliorates autoimmune encephalomyelitis. | 2006 | J. Neuroimmunol. | pmid:16239036 |
| Glaser ST et al. | Endocannabinoids in the intact retina: 3 H-anandamide uptake, fatty acid amide hydrolase immunoreactivity and hydrolysis of anandamide. | 2005 Nov-Dec | Vis. Neurosci. | pmid:16469181 |
| Abalo R et al. | Evaluation of the effect of age on cannabinoid receptor functionality and expression in guinea-pig ileum longitudinal muscle-myenteric plexus preparations. | 2005 Jul 22-29 | Neurosci. Lett. | pmid:15936532 |
| Kurabayashi M et al. | 2-Arachidonoylglycerol increases in ischemia-reperfusion injury of the rat liver. | 2005 Jan-Feb | J Invest Surg | pmid:15804949 |
| Basavarajappa BS and Hungund BL | Role of the endocannabinoid system in the development of tolerance to alcohol. | 2005 Jan-Feb | Alcohol Alcohol. | pmid:15550443 |
| RodrÃguez de Fonseca F et al. | The endocannabinoid system: physiology and pharmacology. | 2005 Jan-Feb | Alcohol Alcohol. | pmid:15550444 |
| Guo Y et al. | N-acylphosphatidylethanolamine-hydrolyzing phospholipase D is an important determinant of uterine anandamide levels during implantation. | 2005 | J. Biol. Chem. | pmid:15890658 |
| Kaplan BL et al. | Inhibition of leukocyte function and interleukin-2 gene expression by 2-methylarachidonyl-(2'-fluoroethyl)amide, a stable congener of the endogenous cannabinoid receptor ligand anandamide. | 2005 | Toxicol. Appl. Pharmacol. | pmid:15893538 |
| van der Stelt M et al. | A role for endocannabinoids in the generation of parkinsonism and levodopa-induced dyskinesia in MPTP-lesioned non-human primate models of Parkinson's disease. | 2005 | FASEB J. | pmid:15894565 |
| Vandevoorde S and Fowler CJ | Inhibition of fatty acid amide hydrolase and monoacylglycerol lipase by the anandamide uptake inhibitor VDM11: evidence that VDM11 acts as an FAAH substrate. | 2005 | Br. J. Pharmacol. | pmid:15895107 |
| Hillard CJ and Jarrahian A | Accumulation of anandamide: evidence for cellular diversity. | 2005 | Neuropharmacology | pmid:15910883 |
| Jia Y et al. | TRPV1 receptor: a target for the treatment of pain, cough, airway disease and urinary incontinence. | 2005 | Drug News Perspect. | pmid:15915217 |
| Sancho R et al. | Mechanisms of HIV-1 inhibition by the lipid mediator N-arachidonoyldopamine. | 2005 | J. Immunol. | pmid:16148147 |
| Fezza F et al. | Radiochromatographic assay of N-acyl-phosphatidylethanolamine-specific phospholipase D activity. | 2005 | Anal. Biochem. | pmid:15766717 |
| Maccarrone M et al. | Characterization of the endocannabinoid system in boar spermatozoa and implications for sperm capacitation and acrosome reaction. | 2005 | J. Cell. Sci. | pmid:16144868 |
| Chen P et al. | Induction of cyclooxygenase-2 by anandamide in cerebral microvascular endothelium. | 2005 | Microvasc. Res. | pmid:15797258 |
| Randall MD | The cardiovascular actions of anandamide: more targets? | 2005 | Br. J. Pharmacol. | pmid:15834438 |
| Yang W et al. | Enzymatic formation of prostamide F2alpha from anandamide involves a newly identified intermediate metabolite, prostamide H2. | 2005 | J. Lipid Res. | pmid:16150817 |
| Kwolek G et al. | Central and peripheral components of the pressor effect of anandamide in urethane-anaesthetized rats. | 2005 | Br. J. Pharmacol. | pmid:15834445 |
| Gasperi V et al. | Further insights into the regulation of human FAAH by progesterone and leptin implications for endogenous levels of anandamide and apoptosis of immune and neuronal cells. | 2005 | Neurotoxicology | pmid:16154199 |
| Mestre L et al. | Pharmacological modulation of the endocannabinoid system in a viral model of multiple sclerosis. | 2005 | J. Neurochem. | pmid:15748152 |
| Sun YX et al. | Involvement of N-acylethanolamine-hydrolyzing acid amidase in the degradation of anandamide and other N-acylethanolamines in macrophages. | 2005 | Biochim. Biophys. Acta | pmid:16154384 |
| Domenicali M et al. | Increased anandamide induced relaxation in mesenteric arteries of cirrhotic rats: role of cannabinoid and vanilloid receptors. | 2005 | Gut | pmid:15753538 |
| Barun S et al. | Effects of cannabinoid receptor activation on rabbit bisected vas deferens strips. | 2005 | Clin. Exp. Pharmacol. Physiol. | pmid:16173925 |
| Oz M et al. | Effects of saturated long-chain N-acylethanolamines on voltage-dependent Ca2+ fluxes in rabbit T-tubule membranes. | 2005 | Arch. Biochem. Biophys. | pmid:15639235 |
| Underdown NJ et al. | Anandamide reduces infarct size in rat isolated hearts subjected to ischaemia-reperfusion by a novel cannabinoid mechanism. | 2005 | Br. J. Pharmacol. | pmid:16158067 |
| Wang Y et al. | VR1-mediated depressor effects during high-salt intake: role of anandamide. | 2005 | Hypertension | pmid:16144988 |