| MeSH term | MeSH ID | Detail |
|---|---|---|
| Ventricular Fibrillation | D014693 | 16 associated lipids |
| Fever | D005334 | 35 associated lipids |
| Bronchial Spasm | D001986 | 18 associated lipids |
| Morphine Dependence | D009021 | 9 associated lipids |
| Shock, Septic | D012772 | 11 associated lipids |
| Cough | D003371 | 19 associated lipids |
| Encephalomyelitis, Autoimmune, Experimental | D004681 | 26 associated lipids |
| Catalepsy | D002375 | 30 associated lipids |
| Migraine Disorders | D008881 | 11 associated lipids |
| Cardiomyopathy, Dilated | D002311 | 15 associated lipids |
Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Pisani V et al. | Dynamic changes of anandamide in the cerebrospinal fluid of Parkinson's disease patients. | 2010 | Mov. Disord. | pmid:20461809 |
| Bardell TK and Barker EL | Activation of TRPC6 channels promotes endocannabinoid biosynthesis in neuronal CAD cells. | 2010 | Neurochem. Int. | pmid:20466028 |
| Naccarato M et al. | Possible Anandamide and Palmitoylethanolamide involvement in human stroke. | 2010 | Lipids Health Dis | pmid:20470384 |
| Dey R et al. | Endocannabinoids inhibit the growth of free-living amoebae. | 2010 | Antimicrob. Agents Chemother. | pmid:20479202 |
| Bhaskaran MD and Smith BN | Cannabinoid-mediated inhibition of recurrent excitatory circuitry in the dentate gyrus in a mouse model of temporal lobe epilepsy. | 2010 | PLoS ONE | pmid:20498848 |
| Ishiguro H et al. | Functional polymorphism in the GPR55 gene is associated with anorexia nervosa. | 2011 | Synapse | pmid:20506567 |
| Sántha P et al. | The endogenous cannabinoid anandamide inhibits transient receptor potential vanilloid type 1 receptor-mediated currents in rat cultured primary sensory neurons. | 2010 | Acta Physiol Hung | pmid:20511124 |
| Talevi R et al. | Is there a role for endocannabinoids in sperm-oviduct interaction? | 2010 | Reproduction | pmid:20511399 |
| Patsos HA et al. | The endogenous cannabinoid, anandamide, induces COX-2-dependent cell death in apoptosis-resistant colon cancer cells. | 2010 | Int. J. Oncol. | pmid:20514410 |
| Weis F et al. | Effect of anaesthesia and cardiopulmonary bypass on blood endocannabinoid concentrations during cardiac surgery. | 2010 | Br J Anaesth | pmid:20525978 |
| Suárez J et al. | Endocannabinoid system in the adult rat circumventricular areas: an immunohistochemical study. | 2010 | J. Comp. Neurol. | pmid:20533360 |
| Fernandez-Solari J et al. | Participation of the endocannabinoid system in lipopolysaccharide-induced inhibition of salivary secretion. | 2010 | Arch. Oral Biol. | pmid:20542488 |
| Maccarrone M et al. | Intracellular trafficking of anandamide: new concepts for signaling. | 2010 | Trends Biochem. Sci. | pmid:20570522 |
| Lisboa SF et al. | Cannabinoid CB1 receptors in the medial prefrontal cortex modulate the expression of contextual fear conditioning. | 2010 | Int. J. Neuropsychopharmacol. | pmid:20587131 |
| Thors L et al. | Biochanin A, a naturally occurring inhibitor of fatty acid amide hydrolase. | 2010 | Br. J. Pharmacol. | pmid:20590565 |
| Mukhopadhyay P et al. | CB1 cannabinoid receptors promote oxidative/nitrosative stress, inflammation and cell death in a murine nephropathy model. | 2010 | Br. J. Pharmacol. | pmid:20590569 |
| Rajesh M et al. | Cannabinoid-1 receptor activation induces reactive oxygen species-dependent and -independent mitogen-activated protein kinase activation and cell death in human coronary artery endothelial cells. | 2010 | Br. J. Pharmacol. | pmid:20590572 |
| Wheal AJ et al. | Vasorelaxation to N-oleoylethanolamine in rat isolated arteries: mechanisms of action and modulation via cyclooxygenase activity. | 2010 | Br. J. Pharmacol. | pmid:20590573 |
| Gutierrez-Lopez MD et al. | Involvement of 2-arachidonoyl glycerol in the increased consumption of and preference for ethanol of mice treated with neurotoxic doses of methamphetamine. | 2010 | Br. J. Pharmacol. | pmid:20590579 |
| Soneji ND et al. | Effects of cannabinoids on capsaicin receptor activity following exposure of primary sensory neurons to inflammatory mediators. | 2010 | Life Sci. | pmid:20598325 |
| Yang YY et al. | Mechanisms of TNFalpha-induced cardiac dysfunction in cholestatic bile duct-ligated mice: interaction between TNFalpha and endocannabinoids. | 2010 | J. Hepatol. | pmid:20626112 |
| Muccioli GG et al. | The endocannabinoid system links gut microbiota to adipogenesis. | 2010 | Mol. Syst. Biol. | pmid:20664638 |
| Bagavandoss P and Grimshaw S | Temporal and spatial distribution of the cannabinoid receptors (CB1, CB2) and fatty acid amide hydroxylase in the rat ovary. | 2010 | Anat Rec (Hoboken) | pmid:20665820 |
| Linsalata M et al. | Effects of anandamide on polyamine levels and cell growth in human colon cancer cells. | 2010 | Anticancer Res. | pmid:20682986 |
| Soltys J et al. | Regulation of neural progenitor cell fate by anandamide. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20691161 |
| Glaser ST and Kaczocha M | Cyclooxygenase-2 mediates anandamide metabolism in the mouse brain. | 2010 | J. Pharmacol. Exp. Ther. | pmid:20702753 |
| Pratt-Hyatt M et al. | Effects of a commonly occurring genetic polymorphism of human CYP3A4 (I118V) on the metabolism of anandamide. | 2010 | Drug Metab. Dispos. | pmid:20702771 |
| Mair KM et al. | Interaction between anandamide and sphingosine-1-phosphate in mediating vasorelaxation in rat coronary artery. | 2010 | Br. J. Pharmacol. | pmid:20718749 |
| Sagar DR et al. | Tonic modulation of spinal hyperexcitability by the endocannabinoid receptor system in a rat model of osteoarthritis pain. | 2010 | Arthritis Rheum. | pmid:20722027 |
| Bobbala D et al. | Effect of anandamide in Plasmodium Berghei-infected mice. | 2010 | Cell. Physiol. Biochem. | pmid:20798520 |
| Tree K et al. | Anandamide centrally depresses the respiratory rhythm generator of neonatal mice. | 2010 | Neuroscience | pmid:20800658 |
| Jiang S et al. | Endocannabinoids are expressed in bone marrow stromal niches and play a role in interactions of hematopoietic stem and progenitor cells with the bone marrow microenvironment. | 2010 | J. Biol. Chem. | pmid:20826813 |
| Lam PM et al. | Simultaneous measurement of three N-acylethanolamides in human bio-matrices using ultra performance liquid chromatography-tandem mass spectrometry. | 2010 | Anal Bioanal Chem | pmid:20835819 |
| Clapper JR et al. | Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism. | 2010 | Nat. Neurosci. | pmid:20852626 |
| Hutchins HL et al. | Eicosapentaenoic acid decreases expression of anandamide synthesis enzyme and cannabinoid receptor 2 in osteoblast-like cells. | 2011 | J. Nutr. Biochem. | pmid:20951563 |
| Morera-Herreras T et al. | Nigrostriatal denervation changes the effect of cannabinoids on subthalamic neuronal activity in rats. | 2011 | Psychopharmacology (Berl.) | pmid:20959968 |
| Cassano T et al. | Evaluation of the emotional phenotype and serotonergic neurotransmission of fatty acid amide hydrolase-deficient mice. | 2011 | Psychopharmacology (Berl.) | pmid:21042794 |
| Xie S et al. | Inactivation of lipid glyceryl ester metabolism in human THP1 monocytes/macrophages by activated organophosphorus insecticides: role of carboxylesterases 1 and 2. | 2010 | Chem. Res. Toxicol. | pmid:21049984 |
| Justinová Z et al. | Reinforcing and neurochemical effects of cannabinoid CB1 receptor agonists, but not cocaine, are altered by an adenosine A2A receptor antagonist. | 2011 | Addict Biol | pmid:21054689 |
| Amoako AA et al. | Quantitative analysis of anandamide and related acylethanolamides in human seminal plasma by ultra performance liquid chromatography tandem mass spectrometry. | 2010 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:21056015 |
| Naidoo V et al. | A new generation fatty acid amide hydrolase inhibitor protects against kainate-induced excitotoxicity. | 2011 | J. Mol. Neurosci. | pmid:21069475 |
| Edwards JG et al. | A novel non-CB1/TRPV1 endocannabinoid-mediated mechanism depresses excitatory synapses on hippocampal CA1 interneurons. | 2012 | Hippocampus | pmid:21069781 |
| Osman NA et al. | Synthesis, binding studies and molecular modeling of novel cannabinoid receptor ligands. | 2010 | Bioorg. Med. Chem. | pmid:21074998 |
| Chávez AE et al. | TRPV1 activation by endogenous anandamide triggers postsynaptic long-term depression in dentate gyrus. | 2010 | Nat. Neurosci. | pmid:21076423 |
| Godlewski G et al. | Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effects. | 2010 | Chem. Biol. | pmid:21095576 |
| Long JZ et al. | An anatomical and temporal portrait of physiological substrates for fatty acid amide hydrolase. | 2011 | J. Lipid Res. | pmid:21097653 |
| Di Marzo V | Anandamide serves two masters in the brain. | 2010 | Nat. Neurosci. | pmid:21102567 |
| Gomes FV et al. | Facilitation of CB1 receptor-mediated neurotransmission decreases marble burying behavior in mice. | 2011 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:21111767 |
| Kawahara H et al. | Inhibition of fatty acid amide hydrolase unmasks CB1 receptor and TRPV1 channel-mediated modulation of glutamatergic synaptic transmission in midbrain periaqueductal grey. | 2011 | Br. J. Pharmacol. | pmid:21175570 |
| De Petrocellis L et al. | Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes. | 2011 | Br. J. Pharmacol. | pmid:21175579 |
| Jumpertz R et al. | Central and peripheral endocannabinoids and cognate acylethanolamides in humans: association with race, adiposity, and energy expenditure. | 2011 | J. Clin. Endocrinol. Metab. | pmid:21177788 |
| Chadwick W et al. | Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses. | 2010 | PLoS ONE | pmid:21179406 |
| Méndez-DÃaz M et al. | The endocannabinoid system modulates the valence of the emotion associated to food ingestion. | 2012 | Addict Biol | pmid:21182571 |
| Kotsikorou E et al. | Lipid bilayer molecular dynamics study of lipid-derived agonists of the putative cannabinoid receptor, GPR55. | 2011 | Chem. Phys. Lipids | pmid:21185816 |
| Zaccagnino P et al. | Anandamide inhibits oxidative phosphorylation in isolated liver mitochondria. | 2011 | FEBS Lett. | pmid:21187088 |
| Di Marzo V | Endocannabinoid signaling in the brain: biosynthetic mechanisms in the limelight. | 2011 | Nat. Neurosci. | pmid:21187849 |
| Bari M et al. | The manifold actions of endocannabinoids on female and male reproductive events. | 2011 | Front Biosci (Landmark Ed) | pmid:21196184 |
| Guindon J et al. | Peripheral antinociceptive effects of inhibitors of monoacylglycerol lipase in a rat model of inflammatory pain. | 2011 | Br. J. Pharmacol. | pmid:21198549 |
| De Petrocellis L et al. | N-palmitoyl-vanillamide (palvanil) is a non-pungent analogue of capsaicin with stronger desensitizing capability against the TRPV1 receptor and anti-hyperalgesic activity. | 2011 | Pharmacol. Res. | pmid:21215315 |
| Jenkin KA et al. | Role for cannabinoid receptors in human proximal tubular hypertrophy. | 2010 | Cell. Physiol. Biochem. | pmid:21220919 |
| Dean C | Endocannabinoid modulation of sympathetic and cardiovascular responses to acute stress in the periaqueductal gray of the rat. | 2011 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:21228344 |
| Zschenderlein C et al. | Capsaicin-induced changes in LTP in the lateral amygdala are mediated by TRPV1. | 2011 | PLoS ONE | pmid:21249195 |
| Hollis JH et al. | The endocannabinoid arachidonylethanolamide attenuates aspects of lipopolysaccharide-induced changes in energy intake, energy expenditure and hypothalamic Fos expression. | 2011 | J. Neuroimmunol. | pmid:21262543 |
| Wang W et al. | Enhancement of apamin-sensitive medium afterhyperpolarization current by anandamide and its role in excitability control in cultured hippocampal neurons. | 2011 | Neuropharmacology | pmid:21272594 |
| Reis GM et al. | Endogenous cannabinoid receptor agonist anandamide induces peripheral antinociception by activation of ATP-sensitive K+ channels. | 2011 | Life Sci. | pmid:21277864 |
| Sridar C et al. | Anandamide oxidation by wild-type and polymorphically expressed CYP2B6 and CYP2D6. | 2011 | Drug Metab. Dispos. | pmid:21289075 |
| Garami A et al. | Thermoregulatory phenotype of the Trpv1 knockout mouse: thermoeffector dysbalance with hyperkinesis. | 2011 | J. Neurosci. | pmid:21289181 |
| Walentiny DM et al. | The endogenous cannabinoid anandamide shares discriminative stimulus effects with ∆(9)-tetrahydrocannabinol in fatty acid amide hydrolase knockout mice. | 2011 | Eur. J. Pharmacol. | pmid:21300050 |
| Quercioli A et al. | Elevated endocannabinoid plasma levels are associated with coronary circulatory dysfunction in obesity. | 2011 | Eur. Heart J. | pmid:21303779 |
| Vinod KY et al. | Innate difference in the endocannabinoid signaling and its modulation by alcohol consumption in alcohol-preferring sP rats. | 2012 | Addict Biol | pmid:21309960 |
| Correa F et al. | The endocannabinoid anandamide downregulates IL-23 and IL-12 subunits in a viral model of multiple sclerosis: evidence for a cross-talk between IL-12p70/IL-23 axis and IL-10 in microglial cells. | 2011 | Brain Behav. Immun. | pmid:21310228 |
| Signorello MG et al. | The anandamide effect on NO/cGMP pathway in human platelets. | 2011 | J. Cell. Biochem. | pmid:21328466 |
| Greco R et al. | Effects of anandamide in migraine: data from an animal model. | 2011 | J Headache Pain | pmid:21331757 |
| Gervasi MG et al. | Anandamide capacitates bull spermatozoa through CB1 and TRPV1 activation. | 2011 | PLoS ONE | pmid:21347292 |
| Latek D et al. | Modeling of ligand binding to G protein coupled receptors: cannabinoid CB1, CB2 and adrenergic β 2 AR. | 2011 | J Mol Model | pmid:21365223 |
| Sarmad S et al. | Depolarizing and calcium-mobilizing stimuli fail to enhance synthesis and release of endocannabinoids from rat brain cerebral cortex slices. | 2011 | J. Neurochem. | pmid:21375532 |
| Mukhopadhyay B et al. | Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver. | 2011 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21383171 |
| Proto MC et al. | Interaction of endocannabinoid system and steroid hormones in the control of colon cancer cell growth. | 2012 | J. Cell. Physiol. | pmid:21412772 |
| Pinar-Sueiro S et al. | [Cannabinoid applications in glaucoma]. | 2011 | Arch Soc Esp Oftalmol | pmid:21414525 |
| Aberturas MR et al. | Anandamide-loaded nanoparticles: preparation and characterization. | 2011 | J Microencapsul | pmid:21425945 |
| Kuc C et al. | Arachidonoyl ethanolamide (AEA)-induced apoptosis is mediated by J-series prostaglandins and is enhanced by fatty acid amide hydrolase (FAAH) blockade. | 2012 | Mol. Carcinog. | pmid:21432910 |
| Khasabova IA et al. | Increasing 2-arachidonoyl glycerol signaling in the periphery attenuates mechanical hyperalgesia in a model of bone cancer pain. | 2011 | Pharmacol. Res. | pmid:21440630 |
| Munguba H et al. | Pre-training anandamide infusion within the basolateral amygdala impairs plus-maze discriminative avoidance task in rats. | 2011 | Neurobiol Learn Mem | pmid:21440651 |
| Stewart JL and McMahon LR | The fatty acid amide hydrolase inhibitor URB 597: interactions with anandamide in rhesus monkeys. | 2011 | Br. J. Pharmacol. | pmid:21449917 |
| Huang L et al. | Anandamide exerts its antiproliferative actions on cholangiocarcinoma by activation of the GPR55 receptor. | 2011 | Lab. Invest. | pmid:21464819 |
| Rossi S et al. | Cannabinoid CB1 receptors regulate neuronal TNF-α effects in experimental autoimmune encephalomyelitis. | 2011 | Brain Behav. Immun. | pmid:21473912 |
| Brighton PJ et al. | Characterization of the endocannabinoid system, CB(1) receptor signalling and desensitization in human myometrium. | 2011 | Br. J. Pharmacol. | pmid:21486283 |
| Steiner AA et al. | The hypothermic response to bacterial lipopolysaccharide critically depends on brain CB1, but not CB2 or TRPV1, receptors. | 2011 | J. Physiol. (Lond.) | pmid:21486787 |
| Izzo AA and Deutsch DG | Unique pathway for anandamide synthesis and liver regeneration. | 2011 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21490298 |
| Chiba T et al. | A synthetic cannabinoid, CP55940, inhibits lipopolysaccharide-induced cytokine mRNA expression in a cannabinoid receptor-independent mechanism in rat cerebellar granule cells. | 2011 | J. Pharm. Pharmacol. | pmid:21492165 |
| Gamaleddin I et al. | The selective anandamide transport inhibitor VDM11 attenuates reinstatement of nicotine seeking behaviour, but does not affect nicotine intake. | 2011 | Br. J. Pharmacol. | pmid:21501143 |
| Booker L et al. | The fatty acid amide hydrolase (FAAH) inhibitor PF-3845 acts in the nervous system to reverse LPS-induced tactile allodynia in mice. | 2012 | Br. J. Pharmacol. | pmid:21506952 |
| Carr RL et al. | Effect of developmental chlorpyrifos exposure, on endocannabinoid metabolizing enzymes, in the brain of juvenile rats. | 2011 | Toxicol. Sci. | pmid:21507991 |
| Engel MA et al. | Inhibitory CB1 and activating/desensitizing TRPV1-mediated cannabinoid actions on CGRP release in rodent skin. | 2011 | Neuropeptides | pmid:21514666 |
| Qi J et al. | Painful pathways induced by TLR stimulation of dorsal root ganglion neurons. | 2011 | J. Immunol. | pmid:21515789 |
| Howlett AC et al. | Endocannabinoid tone versus constitutive activity of cannabinoid receptors. | 2011 | Br. J. Pharmacol. | pmid:21545414 |
| Jung KM et al. | An amyloid β42-dependent deficit in anandamide mobilization is associated with cognitive dysfunction in Alzheimer's disease. | 2012 | Neurobiol. Aging | pmid:21546126 |
| Umathe SN et al. | Involvement of endocannabinoids in antidepressant and anti-compulsive effect of fluoxetine in mice. | 2011 | Behav. Brain Res. | pmid:21549765 |
| Arias-Carrión O et al. | Biochemical modulation of the sleep-wake cycle: endogenous sleep-inducing factors. | 2011 | J. Neurosci. Res. | pmid:21557294 |
| Scherma M et al. | The anandamide transport inhibitor AM404 reduces the rewarding effects of nicotine and nicotine-induced dopamine elevations in the nucleus accumbens shell in rats. | 2012 | Br. J. Pharmacol. | pmid:21557729 |