| MeSH term | MeSH ID | Detail |
|---|---|---|
| Ventricular Fibrillation | D014693 | 16 associated lipids |
| Fever | D005334 | 35 associated lipids |
| Bronchial Spasm | D001986 | 18 associated lipids |
| Morphine Dependence | D009021 | 9 associated lipids |
| Shock, Septic | D012772 | 11 associated lipids |
| Cough | D003371 | 19 associated lipids |
| Encephalomyelitis, Autoimmune, Experimental | D004681 | 26 associated lipids |
| Catalepsy | D002375 | 30 associated lipids |
| Migraine Disorders | D008881 | 11 associated lipids |
| Cardiomyopathy, Dilated | D002311 | 15 associated lipids |
Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| del Carmen GarcÃa M et al. | Hypotensive effect of anandamide through the activation of CB1 and VR1 spinal receptors in urethane-anesthetized rats. | 2003 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:14504685 |
| Barinaga M | Pot, heroin unlock new areas for neuroscience. | 1992 | Science | pmid:1335165 |
| Hillard CJ and Jarrahian A | Cellular accumulation of anandamide: consensus and controversy. | 2003 | Br. J. Pharmacol. | pmid:12970089 |
| Segall Y et al. | Arachidonylsulfonyl derivatives as cannabinoid CB1 receptor and fatty acid amide hydrolase inhibitors. | 2003 | Bioorg. Med. Chem. Lett. | pmid:12951114 |
| Liu J et al. | Lipopolysaccharide induces anandamide synthesis in macrophages via CD14/MAPK/phosphoinositide 3-kinase/NF-kappaB independently of platelet-activating factor. | 2003 | J. Biol. Chem. | pmid:12949078 |
| Fowler CJ et al. | Inhibition of C6 glioma cell proliferation by anandamide, 1-arachidonoylglycerol, and by a water soluble phosphate ester of anandamide: variability in response and involvement of arachidonic acid. | 2003 | Biochem. Pharmacol. | pmid:12948856 |
| Franklin A et al. | Palmitoylethanolamide increases after focal cerebral ischemia and potentiates microglial cell motility. | 2003 | J. Neurosci. | pmid:12944505 |
| Helyes Z et al. | Inhibitory effect of anandamide on resiniferatoxin-induced sensory neuropeptide release in vivo and neuropathic hyperalgesia in the rat. | 2003 | Life Sci. | pmid:12941436 |
| Cravatt BF and Lichtman AH | Fatty acid amide hydrolase: an emerging therapeutic target in the endocannabinoid system. | 2003 | Curr Opin Chem Biol | pmid:12941421 |
| Maccarrone M and Finazzi-Agró A | The endocannabinoid system, anandamide and the regulation of mammalian cell apoptosis. | 2003 | Cell Death Differ. | pmid:12934069 |
| Fasia L et al. | Uptake and metabolism of [3H]anandamide by rabbit platelets. Lack of transporter? | 2003 | Eur. J. Biochem. | pmid:12919314 |
| Dogulu FH et al. | Intra-arterial simultaneous administration of anandamide attenuates endothelin-1 induced vasospasm in rabbit basilar arteries. | 2003 | Acta Neurochir (Wien) | pmid:12910401 |
| Storr M et al. | Cannabinoid receptor type 1 modulates excitatory and inhibitory neurotransmission in mouse colon. | 2004 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:12893627 |
| Kozak KR et al. | Amino acid determinants in cyclooxygenase-2 oxygenation of the endocannabinoid anandamide. | 2003 | Biochemistry | pmid:12885237 |
| Watanabe H et al. | Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels. | 2003 | Nature | pmid:12879072 |
| Sokal DM et al. | Intraplantar injection of anandamide inhibits mechanically-evoked responses of spinal neurones via activation of CB2 receptors in anaesthetised rats. | 2003 | Neuropharmacology | pmid:12871657 |
| Sarker KP and Maruyama I | Anandamide induces cell death independently of cannabinoid receptors or vanilloid receptor 1: possible involvement of lipid rafts. | 2003 | Cell. Mol. Life Sci. | pmid:12861385 |
| González S et al. | Region-dependent changes in endocannabinoid transmission in the brain of morphine-dependent rats. | 2003 | Addict Biol | pmid:12850774 |
| Patel S et al. | The general anesthetic propofol increases brain N-arachidonylethanolamine (anandamide) content and inhibits fatty acid amide hydrolase. | 2003 | Br. J. Pharmacol. | pmid:12839875 |
| Bojesen IN and Hansen HS | Binding of anandamide to bovine serum albumin. | 2003 | J. Lipid Res. | pmid:12837852 |
| Nicholson RA et al. | Sodium channel inhibition by anandamide and synthetic cannabimimetics in brain. | 2003 | Brain Res. | pmid:12834914 |
| Obata T et al. | Simultaneous determination of endocannabinoids (arachidonylethanolamide and 2-arachidonylglycerol) and isoprostane (8-epiprostaglandin F2alpha) by gas chromatography-mass spectrometry-selected ion monitoring for medical samples. | 2003 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:12829006 |
| Ahluwalia J et al. | Anandamide regulates neuropeptide release from capsaicin-sensitive primary sensory neurons by activating both the cannabinoid 1 receptor and the vanilloid receptor 1 in vitro. | 2003 | Eur. J. Neurosci. | pmid:12823468 |
| Maccarrone M et al. | The endocannabinoid system in human keratinocytes. Evidence that anandamide inhibits epidermal differentiation through CB1 receptor-dependent inhibition of protein kinase C, activation protein-1, and transglutaminase. | 2003 | J. Biol. Chem. | pmid:12815050 |
| Wilson SJ et al. | A high-throughput-compatible assay for determining the activity of fatty acid amide hydrolase. | 2003 | Anal. Biochem. | pmid:12814631 |
| Klegeris A et al. | Reduction of human monocytic cell neurotoxicity and cytokine secretion by ligands of the cannabinoid-type CB2 receptor. | 2003 | Br. J. Pharmacol. | pmid:12813001 |
| Shiraishi T et al. | The presence of ceramidase activity in liver nuclear membrane. | 2003 | Biol. Pharm. Bull. | pmid:12808285 |
| Patel S et al. | Differential regulation of the endocannabinoids anandamide and 2-arachidonylglycerol within the limbic forebrain by dopamine receptor activity. | 2003 | J. Pharmacol. Exp. Ther. | pmid:12808005 |
| Han J et al. | Properties and modulation of the G protein-coupled K+ channel in rat cerebellar granule neurons: ATP versus phosphatidylinositol 4,5-bisphosphate. | 2003 | J. Physiol. (Lond.) | pmid:12807991 |
| Maccarrone M et al. | Progesterone activates fatty acid amide hydrolase (FAAH) promoter in human T lymphocytes through the transcription factor Ikaros. Evidence for a synergistic effect of leptin. | 2003 | J. Biol. Chem. | pmid:12799380 |
| El Fangour S et al. | Hemisynthesis and preliminary evaluation of novel endocannabinoid analogues. | 2003 | Bioorg. Med. Chem. Lett. | pmid:12781177 |
| Vásquez C et al. | Effects of cannabinoids on endogenous K+ and Ca2+ currents in HEK293 cells. | 2003 | Can. J. Physiol. Pharmacol. | pmid:12774849 |
| Tarzia G et al. | Design, synthesis, and structure-activity relationships of alkylcarbamic acid aryl esters, a new class of fatty acid amide hydrolase inhibitors. | 2003 | J. Med. Chem. | pmid:12773040 |
| Oz M et al. | The endogenous cannabinoid anandamide inhibits alpha7 nicotinic acetylcholine receptor-mediated responses in Xenopus oocytes. | 2003 | J. Pharmacol. Exp. Ther. | pmid:12766252 |
| Veldhuis WB et al. | Neuroprotection by the endogenous cannabinoid anandamide and arvanil against in vivo excitotoxicity in the rat: role of vanilloid receptors and lipoxygenases. | 2003 | J. Neurosci. | pmid:12764100 |
| Ahern GP | Activation of TRPV1 by the satiety factor oleoylethanolamide. | 2003 | J. Biol. Chem. | pmid:12761211 |
| Tóth A et al. | Arachidonyl dopamine as a ligand for the vanilloid receptor VR1 of the rat. | 2003 | Life Sci. | pmid:12759142 |
| Fowler CJ et al. | Acidic nonsteroidal anti-inflammatory drugs inhibit rat brain fatty acid amide hydrolase in a pH-dependent manner. | 2003 | J Enzyme Inhib Med Chem | pmid:12751821 |
| López-RodrÃguez ML et al. | Design, synthesis and biological evaluation of new endocannabinoid transporter inhibitors. | 2003 | Eur J Med Chem | pmid:12750028 |
| Mimeault M et al. | Anti-proliferative and apoptotic effects of anandamide in human prostatic cancer cell lines: implication of epidermal growth factor receptor down-regulation and ceramide production. | 2003 | Prostate | pmid:12746841 |
| Hermann H et al. | Dual effect of cannabinoid CB1 receptor stimulation on a vanilloid VR1 receptor-mediated response. | 2003 | Cell. Mol. Life Sci. | pmid:12737320 |
| Clement AB et al. | Increased seizure susceptibility and proconvulsant activity of anandamide in mice lacking fatty acid amide hydrolase. | 2003 | J. Neurosci. | pmid:12736361 |
| Ortar G et al. | Novel selective and metabolically stable inhibitors of anandamide cellular uptake. | 2003 | Biochem. Pharmacol. | pmid:12732359 |
| Juntunen J et al. | Anandamide prodrugs. 1. Water-soluble phosphate esters of arachidonylethanolamide and R-methanandamide. | 2003 | Eur J Pharm Sci | pmid:12729860 |
| Yamaji K et al. | Anandamide induces apoptosis in human endothelial cells: its regulation system and clinical implications. | 2003 | Thromb. Haemost. | pmid:12719786 |
| Maccarrone M | The blissful state of endothelium. | 2003 | Thromb. Haemost. | pmid:12719771 |
| Marinelli S et al. | Presynaptic facilitation of glutamatergic synapses to dopaminergic neurons of the rat substantia nigra by endogenous stimulation of vanilloid receptors. | 2003 | J. Neurosci. | pmid:12716921 |
| Maccarrone M et al. | Levodopa treatment reverses endocannabinoid system abnormalities in experimental parkinsonism. | 2003 | J. Neurochem. | pmid:12716433 |
| Jonsson KO et al. | AM404 and VDM 11 non-specifically inhibit C6 glioma cell proliferation at concentrations used to block the cellular accumulation of the endocannabinoid anandamide. | 2003 | Arch. Toxicol. | pmid:12698235 |
| Basavarajappa BS et al. | Chronic ethanol inhibits the anandamide transport and increases extracellular anandamide levels in cerebellar granule neurons. | 2003 | Eur. J. Pharmacol. | pmid:12679143 |
| Costanzi M et al. | Anandamide and memory in CD1 mice: effects of immobilization stress and of prior experience. | 2003 | Neurobiol Learn Mem | pmid:12676519 |
| López-RodrÃguez ML et al. | Design, synthesis, and biological evaluation of new inhibitors of the endocannabinoid uptake: comparison with effects on fatty acid amidohydrolase. | 2003 | J. Med. Chem. | pmid:12672252 |
| Vandevoorde S et al. | Modifications of the ethanolamine head in N-palmitoylethanolamine: synthesis and evaluation of new agents interfering with the metabolism of anandamide. | 2003 | J. Med. Chem. | pmid:12672243 |
| Melck D et al. | Cannabimimetic eicosanoids in cancer and inflammation: an update. | 2002 | Adv. Exp. Med. Biol. | pmid:12664614 |
| Derkinderen P et al. | Regulation of extracellular signal-regulated kinase by cannabinoids in hippocampus. | 2003 | J. Neurosci. | pmid:12657697 |
| Glaser ST et al. | Evidence against the presence of an anandamide transporter. | 2003 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12655057 |
| Holt S and Fowler CJ | Anandamide metabolism by fatty acid amide hydrolase in intact C6 glioma cells. Increased sensitivity to inhibition by ibuprofen and flurbiprofen upon reduction of extra- but not intracellular pH. | 2003 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:12644895 |
| Sarker KP et al. | ASK1-p38 MAPK/JNK signaling cascade mediates anandamide-induced PC12 cell death. | 2003 | J. Neurochem. | pmid:12641726 |
| Campanucci VA et al. | A novel O2-sensing mechanism in rat glossopharyngeal neurones mediated by a halothane-inhibitable background K+ conductance. | 2003 | J. Physiol. (Lond.) | pmid:12640017 |
| Perrier JF et al. | 5-HT1A receptors increase excitability of spinal motoneurons by inhibiting a TASK-1-like K+ current in the adult turtle. | 2003 | J. Physiol. (Lond.) | pmid:12626670 |
| Li J et al. | Anandamide-induced depressor effect in spontaneously hypertensive rats: role of the vanilloid receptor. | 2003 | Hypertension | pmid:12623992 |
| Lau AH and Chow SS | Effects of cannabinoid receptor agonists on immunologically induced histamine release from rat peritoneal mast cells. | 2003 | Eur. J. Pharmacol. | pmid:12620517 |
| Vandevoorde S et al. | N-Morpholino- and N-diethyl-analogues of palmitoylethanolamide increase the sensitivity of transfected human vanilloid receptors to activation by anandamide without affecting fatty acid amidohydrolase activity. | 2003 | Bioorg. Med. Chem. | pmid:12614867 |
| Wisnoskey BJ et al. | Activation of vanilloid receptor type I in the endoplasmic reticulum fails to activate store-operated Ca2+ entry. | 2003 | Biochem. J. | pmid:12608892 |
| Randall MD | A new endothelial target for cannabinoids. | 2003 | Mol. Pharmacol. | pmid:12606752 |
| Scorticati C et al. | The effect of anandamide on prolactin secretion is modulated by estrogen. | 2003 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12578974 |
| Chu CJ et al. | N-oleoyldopamine, a novel endogenous capsaicin-like lipid that produces hyperalgesia. | 2003 | J. Biol. Chem. | pmid:12569099 |
| Lo YK et al. | Effect of arvanil (N-arachidonoyl-vanillyl-amine), a nonpungent anandamide-capsaicin hybrid, on ion currents in NG108-15 neuronal cells. | 2003 | Biochem. Pharmacol. | pmid:12566085 |
| Jennings EA et al. | The actions of anandamide on rat superficial medullary dorsal horn neurons in vitro. | 2003 | J. Physiol. (Lond.) | pmid:12562891 |
| Pearlman RJ et al. | Arachidonic acid and anandamide have opposite modulatory actions at the glycine transporter, GLYT1a. | 2003 | J. Neurochem. | pmid:12558979 |
| Ahluwalia J et al. | Activation of capsaicin-sensitive primary sensory neurones induces anandamide production and release. | 2003 | J. Neurochem. | pmid:12558978 |
| Yan MS et al. | [Cannabinoids, cannabinoid receptor and immune response]. | 2000 | Sheng Li Ke Xue Jin Zhan | pmid:12545719 |
| McVey DC et al. | Endocannabinoids induce ileitis in rats via the capsaicin receptor (VR1). | 2003 | J. Pharmacol. Exp. Ther. | pmid:12538826 |
| Sancho R et al. | Anandamide inhibits nuclear factor-kappaB activation through a cannabinoid receptor-independent pathway. | 2003 | Mol. Pharmacol. | pmid:12527815 |
| Facchinetti F et al. | Cannabinoids ablate release of TNFalpha in rat microglial cells stimulated with lypopolysaccharide. | 2003 | Glia | pmid:12509806 |
| Paria BC et al. | Endocannabinoid signaling in synchronizing embryo development and uterine receptivity for implantation. | 2002 | Chem. Phys. Lipids | pmid:12505701 |
| Cravatt BF and Lichtman AH | The enzymatic inactivation of the fatty acid amide class of signaling lipids. | 2002 | Chem. Phys. Lipids | pmid:12505696 |
| Schmid HH et al. | Cell signaling by endocannabinoids and their congeners: questions of selectivity and other challenges. | 2002 | Chem. Phys. Lipids | pmid:12505695 |
| Wiley JL and Martin BR | Cannabinoid pharmacology: implications for additional cannabinoid receptor subtypes. | 2002 | Chem. Phys. Lipids | pmid:12505690 |
| Kunos G et al. | The quest for a vascular endothelial cannabinoid receptor. | 2002 | Chem. Phys. Lipids | pmid:12505689 |
| Razdan RK and Mahadevan A | Recent advances in the synthesis of endocannabinoid related ligands. | 2002 | Chem. Phys. Lipids | pmid:12505687 |
| Palmer SL et al. | Cannabinergic ligands. | 2002 | Chem. Phys. Lipids | pmid:12505686 |
| Németh J et al. | Concentration-dependent dual effect of anandamide on sensory neuropeptide release from isolated rat tracheae. | 2003 | Neurosci. Lett. | pmid:12499047 |
| Liu YC and Wu SN | Block of erg current by linoleoylamide, a sleep-inducing agent, in pituitary GH3 cells. | 2003 | Eur. J. Pharmacol. | pmid:12498905 |
| Lee LY et al. | Functional morphology and physiological properties of bronchopulmonary C-fiber afferents. | 2003 | Anat Rec A Discov Mol Cell Evol Biol | pmid:12494486 |
| Schelegle ES | Functional morphology and physiology of slowly adapting pulmonary stretch receptors. | 2003 | Anat Rec A Discov Mol Cell Evol Biol | pmid:12494485 |
| Orliac ML et al. | Potentiation of anandamide effects in mesenteric beds isolated from endotoxemic rats. | 2003 | J. Pharmacol. Exp. Ther. | pmid:12490589 |
| Maccarrone M et al. | Anandamide activity and degradation are regulated by early postnatal aging and follicle-stimulating hormone in mouse Sertoli cells. | 2003 | Endocrinology | pmid:12488326 |
| Kathuria S et al. | Modulation of anxiety through blockade of anandamide hydrolysis. | 2003 | Nat. Med. | pmid:12461523 |
| Schmid PC et al. | Anandamide and other N-acylethanolamines in human tumors. | 2002 | Lipids | pmid:12458627 |
| Jerman JC et al. | Comparison of effects of anandamide at recombinant and endogenous rat vanilloid receptors. | 2002 | Br J Anaesth | pmid:12453933 |
| Higgs S et al. | Cannabinoid influences on palatability: microstructural analysis of sucrose drinking after delta(9)-tetrahydrocannabinol, anandamide, 2-arachidonoyl glycerol and SR141716. | 2003 | Psychopharmacology (Berl.) | pmid:12447606 |
| Szoke E et al. | Neonatal anandamide treatment results in prolonged mitochondrial damage in the vanilloid receptor type 1-immunoreactive B-type neurons of the rat trigeminal ganglion. | 2002 | Neuroscience | pmid:12435419 |
| van der Stelt M et al. | Acute neuronal injury, excitotoxicity, and the endocannabinoid system. | 2002 Oct-Dec | Mol. Neurobiol. | pmid:12428763 |
| Krylatov AV et al. | Endogenous cannabinoids improve myocardial resistance to arrhythmogenic effects of coronary occlusion and reperfusion: a possible mechanism. | 2002 | Bull. Exp. Biol. Med. | pmid:12428277 |
| Gómez R et al. | A peripheral mechanism for CB1 cannabinoid receptor-dependent modulation of feeding. | 2002 | J. Neurosci. | pmid:12417686 |
| Geraghty DP and Mazzone SB | Respiratory actions of vanilloid receptor agonists in the nucleus of the solitary tract: comparison of resiniferatoxin with non-pungent agents and anandamide. | 2002 | Br. J. Pharmacol. | pmid:12411424 |
| Jia Y et al. | Anandamide induces cough in conscious guinea-pigs through VR1 receptors. | 2002 | Br. J. Pharmacol. | pmid:12411414 |
| Del Arco I et al. | Attenuation of spontaneous opiate withdrawal in mice by the anandamide transport inhibitor AM404. | 2002 | Eur. J. Pharmacol. | pmid:12409011 |
| Mascolo N et al. | The endocannabinoid system and the molecular basis of paralytic ileus in mice. | 2002 | FASEB J. | pmid:12397089 |