Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Hyperinsulinism D006946 27 associated lipids
Endotoxemia D019446 27 associated lipids
Neuralgia D009437 28 associated lipids
Obesity D009765 29 associated lipids
Catalepsy D002375 30 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Memory Disorders D008569 33 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Per page 10 20 50 100 | Total 105

PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Marco EM et al. Long-term consequences of URB597 administration during adolescence on cannabinoid CB1 receptor binding in brain areas. 2009 Brain Res. pmid:19133243
Ho WS and Gardiner SM Acute hypertension reveals depressor and vasodilator effects of cannabinoids in conscious rats. 2009 Br. J. Pharmacol. pmid:19133994
Ferreira SG et al. N-acyldopamines control striatal input terminals via novel ligand-gated cation channels. 2009 Neuropharmacology pmid:19101577
Ozalp A and Barroso B Simultaneous quantitative analysis of N-acylethanolamides in clinical samples. 2009 Anal. Biochem. pmid:19665986
Li D et al. Role of anandamide transporter in regulating calcitonin gene-related peptide production and blood pressure in hypertension. 2009 J. Hypertens. pmid:19462497
Mahmud A et al. Cannabinoid 1 receptor activation inhibits transient receptor potential vanilloid type 1 receptor-mediated cationic influx into rat cultured primary sensory neurons. 2009 Neuroscience pmid:19463903
Vann RE et al. Discriminative stimulus properties of delta9-tetrahydrocannabinol (THC) in C57Bl/6J mice. 2009 Eur. J. Pharmacol. pmid:19470387
Vercelli CA et al. Anandamide regulates lipopolysaccharide-induced nitric oxide synthesis and tissue damage in the murine uterus. 2009 Reprod. Biomed. Online pmid:19490788
Aquila S et al. A new role of anandamide in human sperm: focus on metabolism. 2009 J. Cell. Physiol. pmid:19492411
Kingsley PJ and Marnett LJ Analysis of endocannabinoids, their congeners and COX-2 metabolites. 2009 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:19505857
Dowie MJ et al. Altered CB1 receptor and endocannabinoid levels precede motor symptom onset in a transgenic mouse model of Huntington's disease. 2009 Neuroscience pmid:19524019
Wise LE et al. Fatty acid amide hydrolase (FAAH) knockout mice exhibit enhanced acquisition of an aversive, but not of an appetitive, Barnes maze task. 2009 Neurobiol Learn Mem pmid:19524055
Maeda N et al. Increased serum anandamide level at ruptured plaque site in patients with acute myocardial infarction. 2009 Fundam Clin Pharmacol pmid:19527302
Straiker A and Mackie K Cannabinoid signaling in inhibitory autaptic hippocampal neurons. 2009 Neuroscience pmid:19501632
Kinsey SG et al. Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain. 2009 J. Pharmacol. Exp. Ther. pmid:19502530
Brighton PJ et al. Characterization of anandamide-stimulated cannabinoid receptor signaling in human ULTR myometrial smooth muscle cells. 2009 Mol. Endocrinol. pmid:19477951
Oddi S et al. Molecular identification of albumin and Hsp70 as cytosolic anandamide-binding proteins. 2009 Chem. Biol. pmid:19481477
Reis GM et al. Opioid receptor and NO/cGMP pathway as a mechanism of peripheral antinociceptive action of the cannabinoid receptor agonist anandamide. 2009 Life Sci. pmid:19576231
Umathe SN et al. Endocannabinoids mediate anxiolytic-like effect of acetaminophen via CB1 receptors. 2009 Prog. Neuropsychopharmacol. Biol. Psychiatry pmid:19580839
Murakami T et al. Antimicrobial cathelicidin polypeptide CAP11 suppresses the production and release of septic mediators in D-galactosamine-sensitized endotoxin shock mice. 2009 Int. Immunol. pmid:19556302
Snider NT et al. A cytochrome P450-derived epoxygenated metabolite of anandamide is a potent cannabinoid receptor 2-selective agonist. 2009 Mol. Pharmacol. pmid:19171674
Yates ML and Barker EL Organized trafficking of anandamide and related lipids. 2009 Vitam. Horm. pmid:19647107
Goodfellow CE and Glass M Anandamide receptor signal transduction. 2009 Vitam. Horm. pmid:19647109
Brown AJ and Robin Hiley C Is GPR55 an anandamide receptor? 2009 Vitam. Horm. pmid:19647110
Correa FG et al. The endocannabinoid anandamide from immunomodulation to neuroprotection. Implications for multiple sclerosis. 2009 Vitam. Horm. pmid:19647114
Tóth A et al. Anandamide and the vanilloid receptor (TRPV1). 2009 Vitam. Horm. pmid:19647120
Pasquariello N et al. Regulation of gene transcription and keratinocyte differentiation by anandamide. 2009 Vitam. Horm. pmid:19647122
Alpini G and Demorrow S Changes in the endocannabinoid system may give insight into new and effective treatments for cancer. 2009 Vitam. Horm. pmid:19647123
Astarita G et al. Targeted lipidomics as a tool to investigate endocannabinoid function. 2009 Int. Rev. Neurobiol. pmid:19607960
Francavilla F et al. Characterization of the endocannabinoid system in human spermatozoa and involvement of transient receptor potential vanilloid 1 receptor in their fertilizing ability. 2009 Endocrinology pmid:19608651
Centonze D et al. Altered anandamide degradation in attention-deficit/hyperactivity disorder. 2009 Neurology pmid:19398708
Liu H et al. Endocannabinoids anandamide and its cannabinoid receptors in liver fibrosis after murine schistosomiasis. 2009 J. Huazhong Univ. Sci. Technol. Med. Sci. pmid:19399401
Mazzola C et al. Fatty acid amide hydrolase (FAAH) inhibition enhances memory acquisition through activation of PPAR-alpha nuclear receptors. 2009 Learn. Mem. pmid:19403796
Shen Y et al. A transient receptor potential-like channel mediates synaptic transmission in rod bipolar cells. 2009 J. Neurosci. pmid:19439586
Ahn K et al. Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain. 2009 Chem. Biol. pmid:19389627
Yates ML and Barker EL Inactivation and biotransformation of the endogenous cannabinoids anandamide and 2-arachidonoylglycerol. 2009 Mol. Pharmacol. pmid:19389920
Miyato H et al. Pharmacological synergism between cannabinoids and paclitaxel in gastric cancer cell lines. 2009 J. Surg. Res. pmid:19394652
Balas L et al. Total synthesis of photoactivatable or fluorescent anandamide probes: novel bioactive compounds with angiogenic activity. 2009 J. Med. Chem. pmid:19161308
Carney ST et al. Cannabinoid regulation of nitric oxide synthase I (nNOS) in neuronal cells. 2009 J Neuroimmune Pharmacol pmid:19365734
Gardiner SM et al. Factors influencing the regional haemodynamic responses to methanandamide and anandamide in conscious rats. 2009 Br. J. Pharmacol. pmid:19702785
Guindon J and Hohmann AG The endocannabinoid system and pain. 2009 CNS Neurol Disord Drug Targets pmid:19839937
Karaliota S et al. Anandamide increases the differentiation of rat adipocytes and causes PPARgamma and CB1 receptor upregulation. 2009 Obesity (Silver Spring) pmid:19543211
Marco EM and Viveros MP The critical role of the endocannabinoid system in emotional homeostasis: avoiding excess and deficiencies. 2009 Mini Rev Med Chem pmid:19929814
Vercelli CA et al. Endocannabinoid system and nitric oxide are involved in the deleterious effects of lipopolysaccharide on murine decidua. 2009 Placenta pmid:19428101
Mendiguren A and Pineda J Effect of the CB(1) receptor antagonists rimonabant and AM251 on the firing rate of dorsal raphe nucleus neurons in rat brain slices. 2009 Br. J. Pharmacol. pmid:19845674
Bradshaw HB et al. The endocannabinoid anandamide is a precursor for the signaling lipid N-arachidonoyl glycine by two distinct pathways. 2009 BMC Biochem. pmid:19460156
Li Q et al. Electrophysiological effects of anandamide on rat myocardium. 2009 Br. J. Pharmacol. pmid:20050190
Hiley CR Endocannabinoids and the heart. 2009 J. Cardiovasc. Pharmacol. pmid:19276990
Gratzke C et al. Distribution and function of cannabinoid receptors 1 and 2 in the rat, monkey and human bladder. 2009 J. Urol. pmid:19237169
El-Talatini MR et al. Localisation and function of the endocannabinoid system in the human ovary. 2009 PLoS ONE pmid:19238202
Parker LA et al. The FAAH inhibitor URB-597 interferes with cisplatin- and nicotine-induced vomiting in the Suncus murinus (house musk shrew). 2009 Physiol. Behav. pmid:19239915
Schlosburg JE et al. Targeting fatty acid amide hydrolase (FAAH) to treat pain and inflammation. 2009 AAPS J pmid:19184452
Navarrete CM et al. Opposite effects of anandamide and N-arachidonoyl dopamine in the regulation of prostaglandin E and 8-iso-PGF formation in primary glial cells. 2009 J. Neurochem. pmid:19200337
Tang B et al. Endothelin-1 inhibits background two-pore domain channel TASK-1 in primary human pulmonary artery smooth muscle cells. 2009 Am. J. Respir. Cell Mol. Biol. pmid:19188660
Ribeiro ML et al. 17beta-oestradiol and progesterone regulate anandamide synthesis in the rat uterus. 2009 Reprod. Biomed. Online pmid:19192341
McMahon LR Apparent affinity estimates of rimonabant in combination with anandamide and chemical analogs of anandamide in rhesus monkeys discriminating Delta9-tetrahydrocannabinol. 2009 Psychopharmacology (Berl.) pmid:18592221
McCue JM et al. In vitro synthesis of arachidonoyl amino acids by cytochrome c. 2009 Prostaglandins Other Lipid Mediat. pmid:19683594
Cottone E et al. Goldfish CB1 mRNA expression is affected by fasting and anandamide administration. 2009 Neuroreport pmid:19293731
Villanueva A et al. Central cannabinoid 1 receptor antagonist administration prevents endotoxic hypotension affecting norepinephrine release in the preoptic anterior hypothalamic area. 2009 Shock pmid:19295473
Izzo AA et al. Peripheral endocannabinoid dysregulation in obesity: relation to intestinal motility and energy processing induced by food deprivation and re-feeding. 2009 Br. J. Pharmacol. pmid:19371345
Appendino G et al. Conformationally constrained fatty acid ethanolamides as cannabinoid and vanilloid receptor probes. 2009 J. Med. Chem. pmid:19361197
El-Talatini MR et al. Fluctuation in anandamide levels from ovulation to early pregnancy in in-vitro fertilization-embryo transfer women, and its hormonal regulation. 2009 Hum. Reprod. pmid:19363040
Brizzi A et al. New resorcinol-anandamide "hybrids" as potent cannabinoid receptor ligands endowed with antinociceptive activity in vivo. 2009 J. Med. Chem. pmid:19331413
Koethe D et al. Anandamide elevation in cerebrospinal fluid in initial prodromal states of psychosis. 2009 Br J Psychiatry pmid:19336792
Mangieri RA et al. An endocannabinoid signal associated with desire for alcohol is suppressed in recently abstinent alcoholics. 2009 Psychopharmacology (Berl.) pmid:19343330
Potenzieri C et al. Excitation of cutaneous C nociceptors by intraplantar administration of anandamide. 2009 Brain Res. pmid:19285051
De Petrocellis L and Di Marzo V An introduction to the endocannabinoid system: from the early to the latest concepts. 2009 Best Pract. Res. Clin. Endocrinol. Metab. pmid:19285257
Borrelli F and Izzo AA Role of acylethanolamides in the gastrointestinal tract with special reference to food intake and energy balance. 2009 Best Pract. Res. Clin. Endocrinol. Metab. pmid:19285259
Bermúdez-Silva FJ et al. The role of the pancreatic endocannabinoid system in glucose metabolism. 2009 Best Pract. Res. Clin. Endocrinol. Metab. pmid:19285263
Kaczocha M et al. Identification of intracellular carriers for the endocannabinoid anandamide. 2009 Proc. Natl. Acad. Sci. U.S.A. pmid:19307565
Alenmyr L et al. TRPV1-mediated itch in seasonal allergic rhinitis. 2009 Allergy pmid:19220220
García-García F et al. Sleep-inducing factors. 2009 CNS Neurol Disord Drug Targets pmid:19689305
Tuboly G et al. The antinociceptive interaction of anandamide and adenosine at the spinal level. 2009 Pharmacol. Biochem. Behav. pmid:18760296
Rossi F et al. The endovanilloid/endocannabinoid system in human osteoclasts: possible involvement in bone formation and resorption. 2009 Bone pmid:19059369
Jiang LS et al. Role of activated endocannabinoid system in regulation of cellular cholesterol metabolism in macrophages. 2009 Cardiovasc. Res. pmid:19074161
Aneetha H et al. Alcohol dehydrogenase-catalyzed in vitro oxidation of anandamide to N-arachidonoyl glycine, a lipid mediator: synthesis of N-acyl glycinals. 2009 Bioorg. Med. Chem. Lett. pmid:19013794
Panlilio LV et al. Anandamide-induced behavioral disruption through a vanilloid-dependent mechanism in rats. 2009 Psychopharmacology (Berl.) pmid:19015836
De Petrocellis L et al. Chemical synthesis, pharmacological characterization, and possible formation in unicellular fungi of 3-hydroxy-anandamide. 2009 J. Lipid Res. pmid:19017617
Tuboly G et al. Antinociceptive interactions between anandamide and endomorphin-1 at the spinal level. 2009 Clin. Exp. Pharmacol. Physiol. pmid:19018802
Schacht JP et al. Intermediate cannabis dependence phenotypes and the FAAH C385A variant: an exploratory analysis. 2009 Psychopharmacology (Berl.) pmid:19002671
Araújo JR et al. Effect of cannabinoids upon the uptake of folic acid by BeWo cells. 2009 Pharmacology pmid:19145103
Van Dross RT Metabolism of anandamide by COX-2 is necessary for endocannabinoid-induced cell death in tumorigenic keratinocytes. 2009 Mol. Carcinog. pmid:19148897
Hydock DS et al. Anandamide preserves cardiac function and geometry in an acute doxorubicin cardiotoxicity rat model. 2009 J. Cardiovasc. Pharmacol. Ther. pmid:19129423
Lin YS et al. Sensitization of capsaicin-sensitive lung vagal afferents by anandamide in rats: role of transient receptor potential vanilloid 1 receptors. 2009 J. Appl. Physiol. pmid:19131477
Kurjak M et al. Differential stimulatory effects of cannabinoids on VIP release and NO synthase activity in synaptosomal fractions from rat ileum. 2008 Oct-Dec Neuropeptides pmid:18829105
Lissoni P et al. The endocannabinoid anandamide neither impairs in vitro T-cell function nor induces regulatory T-cell generation. 2008 Nov-Dec Anticancer Res. pmid:19189659
Sakamoto Y et al. Effectiveness of continuous hemodiafiltration using a polymethylmethacrylate membrane hemofilter after polymyxin B-immobilized fiber column therapy of septic shock. 2008 Jan-Feb ASAIO J. pmid:18204329
Moloney GP et al. Synthesis and cannabinoid activity of 1-substituted-indole-3-oxadiazole derivatives: novel agonists for the CB1 receptor. 2008 Eur J Med Chem pmid:17582659
Moreira FA et al. Reduced anxiety-like behaviour induced by genetic and pharmacological inhibition of the endocannabinoid-degrading enzyme fatty acid amide hydrolase (FAAH) is mediated by CB1 receptors. 2008 Neuropharmacology pmid:17709120
Rubio M et al. CB1 receptor blockade reduces the anxiogenic-like response and ameliorates the neurochemical imbalances associated with alcohol withdrawal in rats. 2008 Neuropharmacology pmid:18371990
Evans RM et al. Modulation of sensory neuron potassium conductances by anandamide indicates roles for metabolites. 2008 Br. J. Pharmacol. pmid:18376419
Di Marzo V and Maccarrone M FAAH and anandamide: is 2-AG really the odd one out? 2008 Trends Pharmacol. Sci. pmid:18394720
Kaufmann I et al. Anandamide and neutrophil function in patients with fibromyalgia. 2008 Psychoneuroendocrinology pmid:18395993
Yao F et al. Development of novel tail-modified anandamide analogs. 2008 Bioorg. Med. Chem. Lett. pmid:18723350
Dembiński A et al. Dual, time-dependent deleterious and protective effect of anandamide on the course of cerulein-induced acute pancreatitis. Role of sensory nerves. 2008 Eur. J. Pharmacol. pmid:18593574
Stark K et al. Expression and purification of orphan cytochrome P450 4X1 and oxidation of anandamide. 2008 FEBS J. pmid:18549450
Kamei J et al. [Sensitization of cough sensitivity through activation of C-and/or Adelta fibers]. 2008 Nippon Yakurigaku Zasshi pmid:18552444
Thors L et al. Inhibition of fatty acid amide hydrolase by kaempferol and related naturally occurring flavonoids. 2008 Br. J. Pharmacol. pmid:18552875
da Veiga MA et al. Acute effects of endocannabinoid anandamide and CB1 receptor antagonist, AM251 in the regulation of thyrotropin secretion. 2008 J. Endocrinol. pmid:18755884
Rubino T et al. Role in anxiety behavior of the endocannabinoid system in the prefrontal cortex. 2008 Cereb. Cortex pmid:17921459