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Behavioral pharmacology of cannabinoids with a focus on preclinical models for studying reinforcing and dependence-producing properties. |
2008 |
Curr Drug Abuse Rev |
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2008 |
Mol. Pharmacol. |
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Prolonged glucocorticoid treatment decreases cannabinoid CB1 receptor density in the hippocampus. |
2008 |
Hippocampus |
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A potential function of endocannabinoids in the selection of a navigation strategy by rats. |
2008 |
Psychopharmacology (Berl.) |
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Evaluation of fatty acid amides in the carrageenan-induced paw edema model. |
2008 |
Neuropharmacology |
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Mol Pain |
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High levels of anandamide, an endogenous cannabinoid, block the growth of sheep preimplantation embryos by inducing apoptosis and reversible arrest of cell proliferation. |
2008 |
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2008 |
JAMA |
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2008 |
Biol. Psychiatry |
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2007 Sep-Oct |
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2007 Sep-Oct |
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Endocannabinoid hedonic hotspot for sensory pleasure: anandamide in nucleus accumbens shell enhances 'liking' of a sweet reward. |
2007 |
Neuropsychopharmacology |
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The contribution of VR1 and CB1 receptors and the role of the afferent vagal pathway in modelling of cardio-respiratory effects of anandamide in rats. |
2007 |
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Regulation of brain anandamide by acute administration of ethanol. |
2007 |
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Evaluation of fatty acid amide hydrolase inhibition in murine models of emotionality. |
2007 |
Psychopharmacology (Berl.) |
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2007 |
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2007 |
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2007 |
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Evidence for a modulatory role of cannabinoids on the excitatory NANC neurotransmission in mouse colon. |
2007 |
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Attenuation of allergic contact dermatitis through the endocannabinoid system. |
2007 |
Science |
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Endocannabinoids acting at CB1 receptors mediate the cardiac contractile dysfunction in vivo in cirrhotic rats. |
2007 |
Am. J. Physiol. Heart Circ. Physiol. |
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Quantitative method for the profiling of the endocannabinoid metabolome by LC-atmospheric pressure chemical ionization-MS. |
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Anal. Chem. |
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2007 |
J. Pharmacol. Exp. Ther. |
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Endocannabinoid enhancement protects against kainic acid-induced seizures and associated brain damage. |
2007 |
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Effect of cannabinoids on platelet serotonin uptake. |
2007 |
Addict Biol |
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Design, synthesis, binding, and molecular modeling studies of new potent ligands of cannabinoid receptors. |
2007 |
Bioorg. Med. Chem. |
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2007 |
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2007 |
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Presynaptic Inhibition of GABAA receptor-mediated unitary IPSPs by cannabinoid receptors at synapses between CCK-positive interneurons in rat hippocampus. |
2007 |
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Effects of anandamide and noxious heat on intracellular calcium concentration in nociceptive drg neurons of rats. |
2007 |
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Role of the nitric oxide pathway and the endocannabinoid system in neurogenic relaxation of corpus cavernosum from biliary cirrhotic rats. |
2007 |
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AM404 decreases Fos-immunoreactivity in the spinal cord in a model of inflammatory pain. |
2007 |
Brain Res. |
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Novel inhibitors of fatty acid amide hydrolase. |
2007 |
Bioorg. Med. Chem. Lett. |
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Towards the discovery of novel T-type calcium channel blockers. |
2007 |
Expert Opin. Ther. Targets |
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2007 |
Eur. J. Neurosci. |
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Identification of endocannabinoids and related compounds in human fat cells. |
2007 |
Obesity (Silver Spring) |
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2007 |
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Neural control of blood pressure: focusing on capsaicin-sensitive sensory nerves. |
2007 |
Cardiovasc Hematol Disord Drug Targets |
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Critical enzymes involved in endocannabinoid metabolism. |
2007 |
Protein Pept. Lett. |
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Role of TRPV receptors in respiratory diseases. |
2007 |
Biochim. Biophys. Acta |
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2007 |
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The endocannabinoid system is dysregulated in multiple sclerosis and in experimental autoimmune encephalomyelitis. |
2007 |
Brain |
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2007 |
Mol. Pharmacol. |
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Inhibition of the cellular uptake of anandamide by genistein and its analogue daidzein in cells with different levels of fatty acid amide hydrolase-driven uptake. |
2007 |
Br. J. Pharmacol. |
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The endogenous cannabinoid anandamide inhibits cromakalim-activated K+ currents in follicle-enclosed Xenopus oocytes. |
2007 |
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2007 |
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Cannabinoid CB1 receptor stimulation affords neuroprotection in MPTP-induced neurotoxicity by attenuating S100B up-regulation in vitro. |
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Anandamide and Delta9-tetrahydrocannabinol directly inhibit cells of the immune system via CB2 receptors. |
2007 |
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Cannabinoids inhibit noradrenergic and purinergic sympathetic cotransmission in the rat isolated mesenteric arterial bed. |
2007 |
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CB1 receptor-mediated control of the release of endocannabinoids (as assessed by microdialysis coupled with LC/MS) in the rat hypothalamus. |
2007 |
Eur. J. Neurosci. |
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Endocannabinoids in TNF-alpha and ethanol actions. |
2007 |
Neuroimmunomodulation |
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Cannabinoid (CB1) receptor activation inhibits trigeminovascular neurons. |
2007 |
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Estrogen and isoflavone attenuate stress-induced gastric mucosal injury by inhibiting decreases in gastric tissue levels of CGRP in ovariectomized rats. |
2007 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
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Inhibition of fatty-acid amide hydrolase accelerates acquisition and extinction rates in a spatial memory task. |
2007 |
Neuropsychopharmacology |
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Role of Ca2+-dependent potassium channels in in vitro anandamide-mediated mesenteric vasorelaxation in rats with biliary cirrhosis. |
2007 |
Liver Int. |
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Anandamide improves the impaired nitric oxide-mediated neurogenic relaxation of the corpus cavernosum in diabetic rats: involvement of cannabinoid CB1 and vanilloid VR1 receptors. |
2007 |
BJU Int. |
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Structure-activity relationship of a series of inhibitors of monoacylglycerol hydrolysis--comparison with effects upon fatty acid amide hydrolase. |
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Chronic exposure of sensory neurones to increased levels of nerve growth factor modulates CB1/TRPV1 receptor crosstalk. |
2007 |
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Cardiovascular effects of cannabinoids in conscious spontaneously hypertensive rats. |
2007 |
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Role and regulation of acylethanolamides in energy balance: focus on adipocytes and beta-cells. |
2007 |
Br. J. Pharmacol. |
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Characterization of the vasorelaxant mechanisms of the endocannabinoid anandamide in rat aorta. |
2007 |
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Follicle-stimulating hormone activates fatty acid amide hydrolase by protein kinase A and aromatase-dependent pathways in mouse primary Sertoli cells. |
2007 |
Endocrinology |
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Effects of the FAAH inhibitor, URB597, and anandamide on lithium-induced taste reactivity responses: a measure of nausea in the rat. |
2007 |
Psychopharmacology (Berl.) |
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Anandamide inhibits endothelin-1 production by human cultured endothelial cells: a new vascular action of this endocannabinoid. |
2007 |
Pharmacology |
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Endothelium-dependent metabolism by endocannabinoid hydrolases and cyclooxygenases limits vasorelaxation to anandamide and 2-arachidonoylglycerol. |
2007 |
Br. J. Pharmacol. |
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Effects of chronic nitric oxide synthase inhibition on the cardiovascular responses to cannabinoids in vivo and in vitro. |
2007 |
Br. J. Pharmacol. |
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Potent and selective alpha-ketoheterocycle-based inhibitors of the anandamide and oleamide catabolizing enzyme, fatty acid amide hydrolase. |
2007 |
J. Med. Chem. |
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Oleamide: a fatty acid amide signaling molecule in the cardiovascular system? |
2007 |
Cardiovasc Drug Rev |
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Endocannabinoid regulates blood pressure via activation of the transient receptor potential vanilloid type 1 in Wistar rats fed a high-salt diet. |
2007 |
J. Pharmacol. Exp. Ther. |
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Involvement of the endocannabinoid system in retinal damage after high intraocular pressure-induced ischemia in rats. |
2007 |
Invest. Ophthalmol. Vis. Sci. |
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Anandamide metabolism by human liver and kidney microsomal cytochrome p450 enzymes to form hydroxyeicosatetraenoic and epoxyeicosatrienoic acid ethanolamides. |
2007 |
J. Pharmacol. Exp. Ther. |
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TRPV1 is a novel target for omega-3 polyunsaturated fatty acids. |
2007 |
J. Physiol. (Lond.) |
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The endogenous cannabinoid anandamide produces delta-9-tetrahydrocannabinol-like discriminative and neurochemical effects that are enhanced by inhibition of fatty acid amide hydrolase but not by inhibition of anandamide transport. |
2007 |
J. Pharmacol. Exp. Ther. |
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5-HT1A receptors are involved in the anxiolytic effect of Delta9-tetrahydrocannabinol and AM 404, the anandamide transport inhibitor, in Sprague-Dawley rats. |
2007 |
Eur. J. Pharmacol. |
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Anandamide-induced Ca2+ elevation leading to p38 MAPK phosphorylation and subsequent cell death via apoptosis in human osteosarcoma cells. |
2007 |
Toxicology |
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Harada N and Okajima K |
Inhibition of neutrophil activation by lafutidine, an H2-receptor antagonist, through enhancement of sensory neuron activation contributes to the reduction of stress-induced gastric mucosal injury in rats. |
2007 |
Dig. Dis. Sci. |
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Antiangiogenic activity of the endocannabinoid anandamide: correlation to its tumor-suppressor efficacy. |
2007 |
J. Cell. Physiol. |
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Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors. |
2007 |
Drug Metab. Dispos. |
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Determination of anandamide and other fatty acyl ethanolamides in human serum by electrospray tandem mass spectrometry. |
2007 |
Anal. Biochem. |
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Cannabinoids and neuronal damage: differential effects of THC, AEA and 2-AG on activated microglial cells and degenerating neurons in excitotoxically lesioned rat organotypic hippocampal slice cultures. |
2007 |
Exp. Neurol. |
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New N-arachidonoylserotonin analogues with potential "dual" mechanism of action against pain. |
2007 |
J. Med. Chem. |
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Role of osteopathic manipulative treatment in altering pain biomarkers: a pilot study. |
2007 |
J Am Osteopath Assoc |
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Functional effects of nonsynonymous polymorphisms in the human TRPV1 gene. |
2007 |
Am. J. Physiol. Renal Physiol. |
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Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. |
2007 |
Biochem. Biophys. Res. Commun. |
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Fatty pain cures. |
2007 |
Chem. Biol. |
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Anti-dyskinetic effects of cannabinoids in a rat model of Parkinson's disease: role of CB(1) and TRPV1 receptors. |
2007 |
Exp. Neurol. |
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Studies of anandamide accumulation inhibitors in cerebellar granule neurons: comparison to inhibition of fatty acid amide hydrolase. |
2007 |
J. Mol. Neurosci. |
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Production of the endocannabinoids anandamide and 2-arachidonoylglycerol by endothelial progenitor cells. |
2007 |
FEBS Lett. |
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Evidence for the involvement of cannabinoid CB1 receptors in the bimatoprost-induced contractions on the human isolated ciliary muscle. |
2007 |
Invest. Ophthalmol. Vis. Sci. |
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Effect of anandamide on erythrocyte survival. |
2007 |
Cell. Physiol. Biochem. |
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Mukhopadhyay S and Tulis DA |
Endocannabinoid regulation of matrix metalloproteinases: implications in ischemic stroke. |
2007 |
Cardiovasc Hematol Agents Med Chem |
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Modulation of the endocannabinoid system by lipid rafts. |
2007 |
Curr. Med. Chem. |
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Roles of transient receptor potential vanilloid subtype 1 and cannabinoid type 1 receptors in the brain: neuroprotection versus neurotoxicity. |
2007 |
Mol. Neurobiol. |
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