Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Alveolar Bone Loss D016301 10 associated lipids
Learning Disorders D007859 11 associated lipids
Hyperkinesis D006948 11 associated lipids
Hyperinsulinism D006946 27 associated lipids
Muscle Spasticity D009128 5 associated lipids
Hypothermia D007035 19 associated lipids
Celiac Disease D002446 16 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Hypertension, Portal D006975 12 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Ralevic V et al. Cannabinoid activation of recombinant and endogenous vanilloid receptors. 2001 Eur. J. Pharmacol. pmid:11672565
Christopoulos A and Wilson K Interaction of anandamide with the M(1) and M(4) muscarinic acetylcholine receptors. 2001 Brain Res. pmid:11578621
Fowler CJ et al. Fatty acid amide hydrolase: biochemistry, pharmacology, and therapeutic possibilities for an enzyme hydrolyzing anandamide, 2-arachidonoylglycerol, palmitoylethanolamide, and oleamide. 2001 Biochem. Pharmacol. pmid:11585048
Maingret F et al. The endocannabinoid anandamide is a direct and selective blocker of the background K(+) channel TASK-1. 2001 EMBO J. pmid:11226154
Mendizábal VE et al. Long-term inhibition of nitric oxide synthase potentiates effects of anandamide in the rat mesenteric bed. 2001 Eur. J. Pharmacol. pmid:11567656
Izzo AA et al. Effect of vanilloid drugs on gastrointestinal transit in mice. 2001 Br. J. Pharmacol. pmid:11264233
Baker D et al. Endocannabinoids control spasticity in a multiple sclerosis model. 2001 FASEB J. pmid:11156943
Gauldie SD et al. Anandamide activates peripheral nociceptors in normal and arthritic rat knee joints. 2001 Br. J. Pharmacol. pmid:11159713
Tognetto M et al. Anandamide excites central terminals of dorsal root ganglion neurons via vanilloid receptor-1 activation. 2001 J. Neurosci. pmid:11160380
Hayase T et al. Protective effects of cannabinoid receptor agonists against cocaine and other convulsant-induced toxic behavioural symptoms. 2001 J. Pharm. Pharmacol. pmid:11732755
Hansen HH et al. Anandamide, but not 2-arachidonoylglycerol, accumulates during in vivo neurodegeneration. 2001 J. Neurochem. pmid:11579150
Smith PJ and McQueen DS Anandamide induces cardiovascular and respiratory reflexes via vasosensory nerves in the anaesthetized rat. 2001 Br. J. Pharmacol. pmid:11588121
Maccarrone M et al. Lipopolysaccharide downregulates fatty acid amide hydrolase expression and increases anandamide levels in human peripheral lymphocytes. 2001 Arch. Biochem. Biophys. pmid:11556820
Crozier Willi G et al. Lipids in neural function: modulation of behavior by oral administration of endocannabinoids found in foods. 2001 Nestle Nutr Workshop Ser Clin Perform Programme pmid:11510437
Stella N and Piomelli D Receptor-dependent formation of endogenous cannabinoids in cortical neurons. 2001 Eur. J. Pharmacol. pmid:11513837
Vellani V et al. Protein kinase C activation potentiates gating of the vanilloid receptor VR1 by capsaicin, protons, heat and anandamide. 2001 J. Physiol. (Lond.) pmid:11483711
Maccarrone M et al. Anandamide degradation and N-acylethanolamines level in wild-type and CB1 cannabinoid receptor knockout mice of different ages. 2001 J. Neurochem. pmid:11461969
Ueda N et al. Purification and characterization of an acid amidase selective for N-palmitoylethanolamine, a putative endogenous anti-inflammatory substance. 2001 J. Biol. Chem. pmid:11463796
Cravatt BF et al. Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase. 2001 Proc. Natl. Acad. Sci. U.S.A. pmid:11470906
Senior K Endogenously produced cannabinoids and liver cirrhosis. 2001 Lancet pmid:11454385
Stanford SJ et al. Identification of two distinct vasodilator pathways activated by ATP in the mesenteric bed of the rat. 2001 Br. J. Pharmacol. pmid:11454655
Mang CF et al. Differential effects of anandamide on acetylcholine release in the guinea-pig ileum mediated via vanilloid and non-CB1 cannabinoid receptors. 2001 Br. J. Pharmacol. pmid:11522608
Bradbury J Small part of cannabis puzzle solved by animal studies. 2001 Lancet pmid:11498223
Jonsson KO et al. Effects of homologues and analogues of palmitoylethanolamide upon the inactivation of the endocannabinoid anandamide. 2001 Br. J. Pharmacol. pmid:11498512
Hayase T et al. Protective effects of cannabinoid receptor ligands analogous to anandamide against cocaine toxicity. 2001 Nihon Arukoru Yakubutsu Igakkai Zasshi pmid:11828716
Bifulco M et al. Control by the endogenous cannabinoid system of ras oncogene-dependent tumor growth. 2001 FASEB J. pmid:11687506
De Petrocellis L et al. Palmitoylethanolamide enhances anandamide stimulation of human vanilloid VR1 receptors. 2001 FEBS Lett. pmid:11602256
Bisogno T et al. Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide. 2001 Br. J. Pharmacol. pmid:11606325
D'Souza DC and Kosten TR Cannabinoid antagonists: a treatment in search of an illness. 2001 Arch. Gen. Psychiatry pmid:11296092
Mechoulam R and Fride E Physiology. A hunger for cannabinoids. 2001 Nature pmid:11298428
Smart D et al. Characterisation using FLIPR of human vanilloid VR1 receptor pharmacology. 2001 Eur. J. Pharmacol. pmid:11301059
Bueb JL et al. Receptor-independent effects of natural cannabinoids in rat peritoneal mast cells in vitro. 2001 Biochim. Biophys. Acta pmid:11336796
Kim D and Thayer SA Cannabinoids inhibit the formation of new synapses between hippocampal neurons in culture. 2001 J. Neurosci. pmid:11319244
Kagota S et al. 2-Arachidonoylglycerol, a candidate of endothelium-derived hyperpolarizing factor. 2001 Eur. J. Pharmacol. pmid:11275004
Bisogno T et al. The uptake by cells of 2-arachidonoylglycerol, an endogenous agonist of cannabinoid receptors. 2001 Eur. J. Biochem. pmid:11277920
De Petrocellis L et al. The activity of anandamide at vanilloid VR1 receptors requires facilitated transport across the cell membrane and is limited by intracellular metabolism. 2001 J. Biol. Chem. pmid:11278420
Jacobsson SO and Fowler CJ Characterization of palmitoylethanolamide transport in mouse Neuro-2a neuroblastoma and rat RBL-2H3 basophilic leukaemia cells: comparison with anandamide. 2001 Br. J. Pharmacol. pmid:11309246
Porter AC and Felder CC The endocannabinoid nervous system: unique opportunities for therapeutic intervention. 2001 Pharmacol. Ther. pmid:11448725
Laine K et al. Effects of topical anandamide-transport inhibitors, AM404 and olvanil, on intraocular pressure in normotensive rabbits. 2001 Pharm. Res. pmid:11451037
Holt S et al. Effects of pH on the inhibition of fatty acid amidohydrolase by ibuprofen. 2001 Br. J. Pharmacol. pmid:11399668
Di Marzo V et al. Hypolocomotor effects in rats of capsaicin and two long chain capsaicin homologues. 2001 Eur. J. Pharmacol. pmid:11408034
Breivogel CS et al. Evidence for a new G protein-coupled cannabinoid receptor in mouse brain. 2001 Mol. Pharmacol. pmid:11408610
Wang Y et al. Simultaneous measurement of anandamide and 2-arachidonoylglycerol by polymyxin B-selective adsorption and subsequent high-performance liquid chromatography analysis: increase in endogenous cannabinoids in the sera of patients with endotoxic shock. 2001 Anal. Biochem. pmid:11412008
De Petrocellis L et al. The vanilloid receptor (VR1)-mediated effects of anandamide are potently enhanced by the cAMP-dependent protein kinase. 2001 J. Neurochem. pmid:11413249
Morisset V and Urban L Cannabinoid-induced presynaptic inhibition of glutamatergic EPSCs in substantia gelatinosa neurons of the rat spinal cord. 2001 J. Neurophysiol. pmid:11431486
Bátkai S et al. Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis. 2001 Nat. Med. pmid:11433348
Maccarrone M et al. Progesterone up-regulates anandamide hydrolase in human lymphocytes: role of cytokines and implications for fertility. 2001 J. Immunol. pmid:11390466
Wenger T et al. The central cannabinoid receptor inactivation suppresses endocrine reproductive functions. 2001 Biochem. Biophys. Res. Commun. pmid:11394887
Maccarrone M et al. Gas chromatography-mass spectrometry analysis of endogenous cannabinoids in healthy and tumoral human brain and human cells in culture. 2001 J. Neurochem. pmid:11208922
Berdyshev EV et al. Activation of PAF receptors results in enhanced synthesis of 2-arachidonoylglycerol (2-AG) in immune cells. 2001 FASEB J. pmid:11641243