Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

Cross Reference

Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Alveolar Bone Loss D016301 10 associated lipids
Learning Disorders D007859 11 associated lipids
Hyperkinesis D006948 11 associated lipids
Hyperinsulinism D006946 27 associated lipids
Muscle Spasticity D009128 5 associated lipids
Hypothermia D007035 19 associated lipids
Celiac Disease D002446 16 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Hypertension, Portal D006975 12 associated lipids
Per page 10 20 50 100 | Total 105

PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

Download all related citations
Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Koethe D et al. Sleep deprivation increases oleoylethanolamide in human cerebrospinal fluid. 2009 J Neural Transm pmid:19137236
Adermark L et al. Endocannabinoid-dependent plasticity at GABAergic and glutamatergic synapses in the striatum is regulated by synaptic activity. 2009 Eur. J. Neurosci. pmid:19120438
Wang J and Ueda N Biology of endocannabinoid synthesis system. 2009 Prostaglandins Other Lipid Mediat. pmid:19126434
Acone G et al. Low type I cannabinoid receptor levels characterize placental villous in labouring delivery. 2009 Placenta pmid:19097644
Wheal AJ and Randall MD Effects of hypertension on vasorelaxation to endocannabinoids in vitro. 2009 Eur. J. Pharmacol. pmid:19100733
Escartín-Pérez RE et al. Role of cannabinoid CB1 receptors on macronutrient selection and satiety in rats. 2009 Physiol. Behav. pmid:19150453
Ozalp A and Barroso B Simultaneous quantitative analysis of N-acylethanolamides in clinical samples. 2009 Anal. Biochem. pmid:19665986
Eckardt K et al. Cannabinoid type 1 receptors in human skeletal muscle cells participate in the negative crosstalk between fat and muscle. 2009 Diabetologia pmid:19089403
Karbarz MJ et al. Biochemical and biological properties of 4-(3-phenyl-[1,2,4] thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide, a mechanism-based inhibitor of fatty acid amide hydrolase. 2009 Anesth. Analg. pmid:19095868
Vignali M et al. The endocannabinoid anandamide inhibits potassium conductance in rat cortical astrocytes. 2009 Glia pmid:19031444
Fernandez-Solari J et al. Anandamide injected into the lateral ventricle of the brain inhibits submandibular salivary secretion by attenuating parasympathetic neurotransmission. 2009 Braz. J. Med. Biol. Res. pmid:19448903
Ribeiro A et al. Dose-response effects of systemic anandamide administration in mice sequentially submitted to the open field and elevated plus-maze tests. 2009 Braz. J. Med. Biol. Res. pmid:19448906
Li D et al. Role of anandamide transporter in regulating calcitonin gene-related peptide production and blood pressure in hypertension. 2009 J. Hypertens. pmid:19462497
Mahmud A et al. Cannabinoid 1 receptor activation inhibits transient receptor potential vanilloid type 1 receptor-mediated cationic influx into rat cultured primary sensory neurons. 2009 Neuroscience pmid:19463903
Vann RE et al. Discriminative stimulus properties of delta9-tetrahydrocannabinol (THC) in C57Bl/6J mice. 2009 Eur. J. Pharmacol. pmid:19470387
Vercelli CA et al. Anandamide regulates lipopolysaccharide-induced nitric oxide synthesis and tissue damage in the murine uterus. 2009 Reprod. Biomed. Online pmid:19490788
Aquila S et al. A new role of anandamide in human sperm: focus on metabolism. 2009 J. Cell. Physiol. pmid:19492411
Kingsley PJ and Marnett LJ Analysis of endocannabinoids, their congeners and COX-2 metabolites. 2009 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:19505857
Dowie MJ et al. Altered CB1 receptor and endocannabinoid levels precede motor symptom onset in a transgenic mouse model of Huntington's disease. 2009 Neuroscience pmid:19524019
Guasti L et al. Minocycline treatment inhibits microglial activation and alters spinal levels of endocannabinoids in a rat model of neuropathic pain. 2009 Mol Pain pmid:19570201
Bittner S et al. TASK1 modulates inflammation and neurodegeneration in autoimmune inflammation of the central nervous system. 2009 Brain pmid:19570851
Grimaldi P et al. The endocannabinoid system and pivotal role of the CB2 receptor in mouse spermatogenesis. 2009 Proc. Natl. Acad. Sci. U.S.A. pmid:19541620
Grider JR et al. Modulation of motor and sensory pathways of the peristaltic reflex by cannabinoids. 2009 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:19589944
Batetta B et al. Endocannabinoids may mediate the ability of (n-3) fatty acids to reduce ectopic fat and inflammatory mediators in obese Zucker rats. 2009 J. Nutr. pmid:19549757
Catanzaro G et al. Anandamide increases swelling and reduces calcium sensitivity of mitochondria. 2009 Biochem. Biophys. Res. Commun. pmid:19679102
Fraga D et al. Endogenous cannabinoids induce fever through the activation of CB1 receptors. 2009 Br. J. Pharmacol. pmid:19681872
Lozovaya N et al. Dual modulation of CNS voltage-gated calcium channels by cannabinoids: Focus on CB1 receptor-independent effects. 2009 Cell Calcium pmid:19682741
Okamoto Y et al. Enzymatic formation of anandamide. 2009 Vitam. Horm. pmid:19647106
Yates ML and Barker EL Organized trafficking of anandamide and related lipids. 2009 Vitam. Horm. pmid:19647107
Goodfellow CE and Glass M Anandamide receptor signal transduction. 2009 Vitam. Horm. pmid:19647109
Brown AJ and Robin Hiley C Is GPR55 an anandamide receptor? 2009 Vitam. Horm. pmid:19647110
Correa FG et al. The endocannabinoid anandamide from immunomodulation to neuroprotection. Implications for multiple sclerosis. 2009 Vitam. Horm. pmid:19647114
Tóth A et al. Anandamide and the vanilloid receptor (TRPV1). 2009 Vitam. Horm. pmid:19647120
Pasquariello N et al. Regulation of gene transcription and keratinocyte differentiation by anandamide. 2009 Vitam. Horm. pmid:19647122
Alpini G and Demorrow S Changes in the endocannabinoid system may give insight into new and effective treatments for cancer. 2009 Vitam. Horm. pmid:19647123
Astarita G et al. Targeted lipidomics as a tool to investigate endocannabinoid function. 2009 Int. Rev. Neurobiol. pmid:19607960
Chen L et al. Endogenous anandamide and cannabinoid receptor-2 contribute to electroacupuncture analgesia in rats. 2009 J Pain pmid:19409856
Yang YY et al. Inhibition of hepatic tumour necrosis factor-alpha attenuates the anandamide-induced vasoconstrictive response in cirrhotic rat livers. 2009 Liver Int. pmid:19413671
Hansen HS and Diep TA N-acylethanolamines, anandamide and food intake. 2009 Biochem. Pharmacol. pmid:19413995
Zoerner AA et al. Targeted stable-isotope dilution GC-MS/MS analysis of the endocannabinoid anandamide and other fatty acid ethanol amides in human plasma. 2009 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:19414283
Di Pasquale E et al. The insertion and transport of anandamide in synthetic lipid membranes are both cholesterol-dependent. 2009 PLoS ONE pmid:19330032
Trezza V and Vanderschuren LJ Divergent effects of anandamide transporter inhibitors with different target selectivity on social play behavior in adolescent rats. 2009 J. Pharmacol. Exp. Ther. pmid:18948500
Pelorosso FG et al. The endocannabinoid anandamide inhibits kinin B1 receptor sensitization through cannabinoid CB1 receptor stimulation in human umbilical vein. 2009 Eur. J. Pharmacol. pmid:19022239
Abalo R et al. Postnatal maturation of the gastrointestinal tract: a functional and immunohistochemical study in the guinea-pig ileum at weaning. 2009 Neurosci. Lett. pmid:19819299
Järbe TU et al. Discriminative stimulus functions in rats of AM1346, a high-affinity CB1R selective anandamide analog. 2009 Psychopharmacology (Berl.) pmid:18521574
Bajo M et al. Differential alteration of hippocampal excitatory synaptic transmission by cannabinoid ligands. 2009 J. Neurosci. Res. pmid:18816788
Long JZ et al. Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects. 2009 Nat. Chem. Biol. pmid:19029917
Musella A et al. TRPV1 channels facilitate glutamate transmission in the striatum. 2009 Mol. Cell. Neurosci. pmid:18930149
Meuth SG et al. The neuroprotective impact of the leak potassium channel TASK1 on stroke development in mice. 2009 Neurobiol. Dis. pmid:18930826
Sun X et al. Genetic loss of Faah compromises male fertility in mice. 2009 Biol. Reprod. pmid:18987328
Marczylo TH et al. A solid-phase method for the extraction and measurement of anandamide from multiple human biomatrices. 2009 Anal. Biochem. pmid:18823934
Long JZ et al. Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo. 2009 Proc. Natl. Acad. Sci. U.S.A. pmid:19918051
Hong S et al. Reciprocal changes in vanilloid (TRPV1) and endocannabinoid (CB1) receptors contribute to visceral hyperalgesia in the water avoidance stressed rat. 2009 Gut pmid:18936104
Correa F et al. A role for CB2 receptors in anandamide signalling pathways involved in the regulation of IL-12 and IL-23 in microglial cells. 2009 Biochem. Pharmacol. pmid:18848818
McCue JM et al. In vitro synthesis of arachidonoyl amino acids by cytochrome c. 2009 Prostaglandins Other Lipid Mediat. pmid:19683594
Cottone E et al. Goldfish CB1 mRNA expression is affected by fasting and anandamide administration. 2009 Neuroreport pmid:19293731
Villanueva A et al. Central cannabinoid 1 receptor antagonist administration prevents endotoxic hypotension affecting norepinephrine release in the preoptic anterior hypothalamic area. 2009 Shock pmid:19295473
Izzo AA et al. Peripheral endocannabinoid dysregulation in obesity: relation to intestinal motility and energy processing induced by food deprivation and re-feeding. 2009 Br. J. Pharmacol. pmid:19371345
Appendino G et al. Conformationally constrained fatty acid ethanolamides as cannabinoid and vanilloid receptor probes. 2009 J. Med. Chem. pmid:19361197
El-Talatini MR et al. Fluctuation in anandamide levels from ovulation to early pregnancy in in-vitro fertilization-embryo transfer women, and its hormonal regulation. 2009 Hum. Reprod. pmid:19363040
Clapper JR et al. The endocannabinoid system as a target for the treatment of cannabis dependence. 2009 Neuropharmacology pmid:18691603
Brizzi A et al. New resorcinol-anandamide "hybrids" as potent cannabinoid receptor ligands endowed with antinociceptive activity in vivo. 2009 J. Med. Chem. pmid:19331413
Schroeder C et al. Circulating endocannabinoid concentrations during orthostatic stress. 2009 Clin. Auton. Res. pmid:19756829
Catani MV et al. Expression of the endocannabinoid system in the bi-potential HEL cell line: commitment to the megakaryoblastic lineage by 2-arachidonoylglycerol. 2009 J. Mol. Med. pmid:18820887
Hill MN et al. Suppression of amygdalar endocannabinoid signaling by stress contributes to activation of the hypothalamic-pituitary-adrenal axis. 2009 Neuropsychopharmacology pmid:19710634
Yusifzade K et al. The protective role of anandamide in mesenteric ischemia reperfusion injury in guinea pig. 2009 Bratisl Lek Listy pmid:19711821
Thors L and Fowler CJ Effect of nitric oxide donors on membrane tritium accumulation of endocannabinoids and related endogenous lipids. 2009 Eur. J. Pharmacol. pmid:19715690
Kaufmann I et al. Enhanced anandamide plasma levels in patients with complex regional pain syndrome following traumatic injury: a preliminary report. 2009 Eur Surg Res pmid:19729930
Shinohara Y et al. Cannabinoid in the nucleus accumbens enhances the intake of palatable solution. 2009 Neuroreport pmid:19734811
Campos AC and Guimarães FS Evidence for a potential role for TRPV1 receptors in the dorsolateral periaqueductal gray in the attenuation of the anxiolytic effects of cannabinoids. 2009 Prog. Neuropsychopharmacol. Biol. Psychiatry pmid:19735690
Wyffels L et al. Synthesis, in vitro and in vivo evaluation, and radiolabeling of aryl anandamide analogues as candidate radioligands for in vivo imaging of fatty acid amide hydrolase in the brain. 2009 J. Med. Chem. pmid:19719235
Di Marzo V et al. Role of insulin as a negative regulator of plasma endocannabinoid levels in obese and nonobese subjects. 2009 Eur. J. Endocrinol. pmid:19745037
Cano C et al. Synthesis and pharmacological evaluation of sulfamide-based analogues of anandamide. 2009 Eur J Med Chem pmid:19762126
Centonze D et al. Lack of effect of cannabis-based treatment on clinical and laboratory measures in multiple sclerosis. 2009 Neurol. Sci. pmid:19768368
Jean-Gilles L et al. Plasma endocannabinoid levels in multiple sclerosis. 2009 J. Neurol. Sci. pmid:19695579
Wyffels L et al. Radiosynthesis, in vitro and in vivo evaluation of 123I-labeled anandamide analogues for mapping brain FAAH. 2009 Bioorg. Med. Chem. pmid:19054678
Rossi F et al. The endovanilloid/endocannabinoid system in human osteoclasts: possible involvement in bone formation and resorption. 2009 Bone pmid:19059369
Jiang LS et al. Role of activated endocannabinoid system in regulation of cellular cholesterol metabolism in macrophages. 2009 Cardiovasc. Res. pmid:19074161
Aneetha H et al. Alcohol dehydrogenase-catalyzed in vitro oxidation of anandamide to N-arachidonoyl glycine, a lipid mediator: synthesis of N-acyl glycinals. 2009 Bioorg. Med. Chem. Lett. pmid:19013794
Panlilio LV et al. Anandamide-induced behavioral disruption through a vanilloid-dependent mechanism in rats. 2009 Psychopharmacology (Berl.) pmid:19015836
De Petrocellis L et al. Chemical synthesis, pharmacological characterization, and possible formation in unicellular fungi of 3-hydroxy-anandamide. 2009 J. Lipid Res. pmid:19017617
Tuboly G et al. Antinociceptive interactions between anandamide and endomorphin-1 at the spinal level. 2009 Clin. Exp. Pharmacol. Physiol. pmid:19018802
Schacht JP et al. Intermediate cannabis dependence phenotypes and the FAAH C385A variant: an exploratory analysis. 2009 Psychopharmacology (Berl.) pmid:19002671
Mato S et al. CB1 cannabinoid receptor-dependent and -independent inhibition of depolarization-induced calcium influx in oligodendrocytes. 2009 Glia pmid:18814177
Kurjak M et al. Differential stimulatory effects of cannabinoids on VIP release and NO synthase activity in synaptosomal fractions from rat ileum. 2008 Oct-Dec Neuropeptides pmid:18829105
Lissoni P et al. The endocannabinoid anandamide neither impairs in vitro T-cell function nor induces regulatory T-cell generation. 2008 Nov-Dec Anticancer Res. pmid:19189659
Sakamoto Y et al. Effectiveness of continuous hemodiafiltration using a polymethylmethacrylate membrane hemofilter after polymyxin B-immobilized fiber column therapy of septic shock. 2008 Jan-Feb ASAIO J. pmid:18204329
Jackson SN et al. Volatile anesthetics and endogenous cannabinoid anandamide have additive and independent inhibitory effects on alpha(7)-nicotinic acetylcholine receptor-mediated responses in Xenopus oocytes. 2008 Eur. J. Pharmacol. pmid:18242598
Butt C et al. Endogenous cannabinoid anandamide inhibits nicotinic acetylcholine receptor function in mouse thalamic synaptosomes. 2008 J. Neurochem. pmid:18194436
Oddi S et al. Evidence for the intracellular accumulation of anandamide in adiposomes. 2008 Cell. Mol. Life Sci. pmid:18213445
Palkovits M et al. Regional distribution and effects of postmortal delay on endocannabinoid content of the human brain. 2008 Neuroscience pmid:18343585
Fezza F et al. Characterization of biotin-anandamide, a novel tool for the visualization of anandamide accumulation. 2008 J. Lipid Res. pmid:18316795
Di Filippo M et al. Abnormalities in the cerebrospinal fluid levels of endocannabinoids in multiple sclerosis. 2008 J. Neurol. Neurosurg. Psychiatr. pmid:18535023
Ashton JC et al. Cannabinoid CB1 and CB2 receptor ligand specificity and the development of CB2-selective agonists. 2008 Curr. Med. Chem. pmid:18537620
Njie YF et al. N-arachidonylethanolamide-induced increase in aqueous humor outflow facility. 2008 Invest. Ophthalmol. Vis. Sci. pmid:18539938
Woodward DF et al. The pharmacology and therapeutic relevance of endocannabinoid derived cyclo-oxygenase (COX)-2 products. 2008 Pharmacol. Ther. pmid:18700152
Williams JL et al. K+ channel inhibition modulates the biochemical and morphological differentiation of human placental cytotrophoblast cells in vitro. 2008 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:18703414
Nakata M and Yada T Cannabinoids inhibit insulin secretion and cytosolic Ca2+ oscillation in islet beta-cells via CB1 receptors. 2008 Regul. Pept. pmid:17884194
Butler RK et al. Endocannabinoid-mediated enhancement of fear-conditioned analgesia in rats: opioid receptor dependency and molecular correlates. 2008 Pain pmid:19004548
Gyires K and Zádori Z [Analysis of central mechanisms involved in gastric mucosal integrity]. 2008 Neuropsychopharmacol Hung pmid:18956615