Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Alveolar Bone Loss D016301 10 associated lipids
Learning Disorders D007859 11 associated lipids
Hyperkinesis D006948 11 associated lipids
Hyperinsulinism D006946 27 associated lipids
Muscle Spasticity D009128 5 associated lipids
Hypothermia D007035 19 associated lipids
Celiac Disease D002446 16 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Hypertension, Portal D006975 12 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
McGregor IS et al. A comparison of delta 9-THC and anandamide induced c-fos expression in the rat forebrain. 1998 Brain Res. pmid:9748483
Di Marzo V and Deutsch DG Biochemistry of the endogenous ligands of cannabinoid receptors. 1998 Neurobiol. Dis. pmid:9974173
Piomelli D et al. Endogenous cannabinoid signaling. 1998 Neurobiol. Dis. pmid:9974178
Barnett-Norris J et al. Exploration of biologically relevant conformations of anandamide, 2-arachidonylglycerol, and their analogues using conformational memories. 1998 J. Med. Chem. pmid:9822555
Maccarrone M et al. Anandamide hydrolysis by human cells in culture and brain. 1998 J. Biol. Chem. pmid:9822713
Axelrod J and Felder CC Cannabinoid receptors and their endogenous agonist, anandamide. 1998 Neurochem. Res. pmid:9566594
Randall MD and Kendall DA Endocannabinoids: a new class of vasoactive substances. 1998 Trends Pharmacol. Sci. pmid:9550942
Van der Kloot W et al. Calcitonin gene-related peptide acts presynaptically to increase quantal size and output at frog neuromuscular junctions. 1998 J. Physiol. (Lond.) pmid:9508830
Di Marzo V et al. The novel endogenous cannabinoid 2-arachidonoylglycerol is inactivated by neuronal- and basophil-like cells: connections with anandamide. 1998 Biochem. J. pmid:9512456
Adams IB et al. Assessment of anandamide interaction with the cannabinoid brain receptor: SR 141716A antagonism studies in mice and autoradiographic analysis of receptor binding in rat brain. 1998 J. Pharmacol. Exp. Ther. pmid:9495885
Pratt PF et al. N-arachidonylethanolamide relaxation of bovine coronary artery is not mediated by CB1 cannabinoid receptor. 1998 Am. J. Physiol. pmid:9458889
Paria BC et al. Effects of cannabinoids on preimplantation mouse embryo development and implantation are mediated by brain-type cannabinoid receptors. 1998 Biol. Reprod. pmid:9623610
Brăiloiu C et al. [Endothelium-derived hyperpolarizing factor]. 1998 Jul-Dec Rev Med Chir Soc Med Nat Iasi pmid:10756843
Childers SR and Breivogel CS Cannabis and endogenous cannabinoid systems. 1998 Jun-Jul Drug Alcohol Depend pmid:9716939
Zenor BN et al. Endocrine and other responses to acute administration of cannabinoid compounds to non-stressed male calves. 1999 Life Sci. pmid:10416818
Chaytor AT et al. The endothelial component of cannabinoid-induced relaxation in rabbit mesenteric artery depends on gap junctional communication. 1999 J. Physiol. (Lond.) pmid:10523421
Piomelli D et al. Structural determinants for recognition and translocation by the anandamide transporter. 1999 Proc. Natl. Acad. Sci. U.S.A. pmid:10318965
Mombouli JV et al. Anandamide-induced mobilization of cytosolic Ca2+ in endothelial cells. 1999 Br. J. Pharmacol. pmid:10323591
Watanabe K et al. Pharmacological effects in mice of anandamide and its related fatty acid ethanolamides, and enhancement of cataleptogenic effect of anandamide by phenylmethylsulfonyl fluoride. 1999 Biol. Pharm. Bull. pmid:10328555
Mechoulam R and Ben-Shabat S From gan-zi-gun-nu to anandamide and 2-arachidonoylglycerol: the ongoing story of cannabis. 1999 Nat Prod Rep pmid:10331283
Burstein SH The cannabinoid acids: nonpsychoactive derivatives with therapeutic potential. 1999 Pharmacol. Ther. pmid:10341359
Di Marzo V et al. Metabolism of anandamide and 2-arachidonoylglycerol: an historical overview and some recent developments. 1999 Lipids pmid:10419192
Hansen HS et al. Formation of N-acyl-phosphatidylethanolamine and N-acylethanolamine (including anandamide) during glutamate-induced neurotoxicity. 1999 Lipids pmid:10419193
Giuffrida A et al. Dopamine activation of endogenous cannabinoid signaling in dorsal striatum. 1999 Nat. Neurosci. pmid:10204543
Paria BC et al. Fatty-acid amide hydrolase is expressed in the mouse uterus and embryo during the periimplantation period. 1999 Biol. Reprod. pmid:10208977
Járai Z et al. Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors. 1999 Proc. Natl. Acad. Sci. U.S.A. pmid:10570211
Molderings GJ et al. Presynaptic cannabinoid and imidazoline receptors in the human heart and their potential relationship. 1999 Naunyn Schmiedebergs Arch. Pharmacol. pmid:10494885
Leweke FM et al. Elevated endogenous cannabinoids in schizophrenia. 1999 Neuroreport pmid:10501554
Akinshola BE et al. Anandamide inhibition of recombinant AMPA receptor subunits in Xenopus oocytes is increased by forskolin and 8-bromo-cyclic AMP. 1999 Naunyn Schmiedebergs Arch. Pharmacol. pmid:10543424
Di Marzo V et al. Cannabimimetic fatty acid derivatives: the anandamide family and other endocannabinoids. 1999 Curr. Med. Chem. pmid:10469888
Kuwae T et al. Biosynthesis and turnover of anandamide and other N-acylethanolamines in peritoneal macrophages. 1999 FEBS Lett. pmid:10508930
McAllister SD et al. Cannabinoid receptors can activate and inhibit G protein-coupled inwardly rectifying potassium channels in a xenopus oocyte expression system. 1999 J. Pharmacol. Exp. Ther. pmid:10525080
Yousif MH and Oriowo MA Inhibitory effects of cannabinoid receptor ligands on electrically-evoked responses in rat isolated tracheal ring segments. 1999 Pharmacol. Res. pmid:10527656
Zygmunt PM et al. Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. 1999 Nature pmid:10440374
Martin BR et al. Discovery and characterization of endogenous cannabinoids. 1999 Life Sci. pmid:10462059
Khanolkar AD and Makriyannis A Structure-activity relationships of anandamide, an endogenous cannabinoid ligand. 1999 Life Sci. pmid:10462061
Howlett AC et al. Signal transduction of eicosanoid CB1 receptor ligands. 1999 Life Sci. pmid:10462062
Di Marzo V Biosynthesis and inactivation of endocannabinoids: relevance to their proposed role as neuromodulators. 1999 Life Sci. pmid:10462065
Ueda N et al. An acid amidase hydrolyzing anandamide as an endogenous ligand for cannabinoid receptors. 1999 FEBS Lett. pmid:10431820
Fowler CJ et al. Inhibition of anandamide hydrolysis by the enantiomers of ibuprofen, ketorolac, and flurbiprofen. 1999 Arch. Biochem. Biophys. pmid:9989926
Basavarajappa BS and Hungund BL Chronic ethanol increases the cannabinoid receptor agonist anandamide and its precursor N-arachidonoylphosphatidylethanolamine in SK-N-SH cells. 1999 J. Neurochem. pmid:9930723
Wagner JA et al. Mesenteric vasodilation mediated by endothelial anandamide receptors. 1999 Hypertension pmid:9931142
Goparaju SK et al. Enzymes of porcine brain hydrolyzing 2-arachidonoylglycerol, an endogenous ligand of cannabinoid receptors. 1999 Biochem. Pharmacol. pmid:9933030
Gifford AN et al. Potentiation of the action of anandamide on hippocampal slices by the fatty acid amide hydrolase inhibitor, palmitylsulphonyl fluoride (AM 374). 1999 Eur. J. Pharmacol. pmid:10556675
Melck D et al. Involvement of the cAMP/protein kinase A pathway and of mitogen-activated protein kinase in the anti-proliferative effects of anandamide in human breast cancer cells. 1999 FEBS Lett. pmid:10606728
Castellano C et al. Strain-dependent effects of anandamide on memory consolidation in mice are antagonized by naltrexone. 1999 Behav Pharmacol pmid:10780251
González S et al. Extrapyramidal and neuroendocrine effects of AM404, an inhibitor of the carrier-mediated transport of anandamide. 1999 Life Sci. pmid:10447218
Melck D et al. Unsaturated long-chain N-acyl-vanillyl-amides (N-AVAMs): vanilloid receptor ligands that inhibit anandamide-facilitated transport and bind to CB1 cannabinoid receptors. 1999 Biochem. Biophys. Res. Commun. pmid:10448105
Lang W et al. Substrate specificity and stereoselectivity of rat brain microsomal anandamide amidohydrolase. 1999 J. Med. Chem. pmid:10072686
Bisogno T et al. Biosynthesis and inactivation of N-arachidonoylethanolamine (anandamide) and N-docosahexaenoylethanolamine in bovine retina. 1999 Arch. Biochem. Biophys. pmid:10577359