Millns PJ et al. |
Effects of inhibition of fatty acid amide hydrolase vs. the anandamide membrane transporter on TRPV1-mediated calcium responses in adult DRG neurons; the role of CB receptors. |
2006 |
Eur. J. Neurosci. |
pmid:17229097
|
Nilsson O et al. |
The cannabinoid agonist WIN 55,212-2 inhibits TNF-alpha-induced neutrophil transmigration across ECV304 cells. |
2006 |
Eur. J. Pharmacol. |
pmid:16928371
|
Schuel H |
Tuning the oviduct to the anandamide tone. |
2006 |
J. Clin. Invest. |
pmid:16886056
|
Kasai HF et al. |
Studies on high-energy collision-induced dissociation of endogenous cannabinoids: 2-arachidonoylglycerol and n-arachidonoylethanolamide in FAB-mass spectrometry. |
2006 |
Anal Sci |
pmid:16837740
|
Murillo-RodrÃguez E et al. |
Cannabidiol, a constituent of Cannabis sativa, modulates sleep in rats. |
2006 |
FEBS Lett. |
pmid:16844117
|
Liu J et al. |
A biosynthetic pathway for anandamide. |
2006 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:16938887
|
Mechoulam R et al. |
Endocannabinoids, feeding and suckling--from our perspective. |
2006 |
Int J Obes (Lond) |
pmid:16570101
|
Matias I et al. |
Endogenous cannabinoids in the brain and peripheral tissues: regulation of their levels and control of food intake. |
2006 |
Int J Obes (Lond) |
pmid:16570107
|
Schiano Moriello A et al. |
Development of the first potential covalent inhibitors of anandamide cellular uptake. |
2006 |
J. Med. Chem. |
pmid:16570928
|
Kudo R and Hatake K |
[Effect of ethanol on anandamide-induced sensory nerve dependent vasorelaxation]. |
2006 |
Nihon Arukoru Yakubutsu Igakkai Zasshi |
pmid:17313058
|
Appendino G et al. |
Oxyhomologues of anandamide and related endolipids: chemoselective synthesis and biological activity. |
2006 |
J. Med. Chem. |
pmid:16570929
|
Chang L et al. |
Inhibition of fatty acid amide hydrolase produces analgesia by multiple mechanisms. |
2006 |
Br. J. Pharmacol. |
pmid:16501580
|
Fezza F et al. |
Methods to assay anandamide hydrolysis and transport in synaptosomes. |
2006 |
Methods Mol. Med. |
pmid:16506407
|
Kaczocha M et al. |
Anandamide uptake is consistent with rate-limited diffusion and is regulated by the degree of its hydrolysis by fatty acid amide hydrolase. |
2006 |
J. Biol. Chem. |
pmid:16461355
|
Waku K |
[Endogenous cannabinoid receptor ligands--anandamide and 2-arachidonoylglycerol]. |
2006 |
Yakugaku Zasshi |
pmid:16462096
|
Petersen G et al. |
Intestinal levels of anandamide and oleoylethanolamide in food-deprived rats are regulated through their precursors. |
2006 |
Biochim. Biophys. Acta |
pmid:16478679
|
Guindon J et al. |
Local interactions between anandamide, an endocannabinoid, and ibuprofen, a nonsteroidal anti-inflammatory drug, in acute and inflammatory pain. |
2006 |
Pain |
pmid:16480822
|
Busch L et al. |
Effects of castration on cannabinoid cb receptor expression and on the biological actions of cannabinoid in the parotid gland. |
2006 |
Clin. Exp. Pharmacol. Physiol. |
pmid:16487271
|
Schelling G et al. |
Effects of general anesthesia on anandamide blood levels in humans. |
2006 |
Anesthesiology |
pmid:16436846
|
Matias I et al. |
Changes in endocannabinoid and palmitoylethanolamide levels in eye tissues of patients with diabetic retinopathy and age-related macular degeneration. |
2006 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:17011761
|
Bari M et al. |
Effect of lipid rafts on Cb2 receptor signaling and 2-arachidonoyl-glycerol metabolism in human immune cells. |
2006 |
J. Immunol. |
pmid:17015679
|
Tan B et al. |
Targeted lipidomics: discovery of new fatty acyl amides. |
2006 |
AAPS J |
pmid:17025263
|
Guindon J et al. |
Synergistic antinociceptive effects of anandamide, an endocannabinoid, and nonsteroidal anti-inflammatory drugs in peripheral tissue: a role for endogenous fatty-acid ethanolamides? |
2006 |
Eur. J. Pharmacol. |
pmid:17027744
|
Prestifilippo JP et al. |
Inhibition of salivary secretion by activation of cannabinoid receptors. |
2006 |
Exp. Biol. Med. (Maywood) |
pmid:16946411
|
Spoto B et al. |
Human adipose tissue binds and metabolizes the endocannabinoids anandamide and 2-arachidonoylglycerol. |
2006 |
Biochimie |
pmid:16949718
|
Vlachou S et al. |
Effects of endocannabinoid neurotransmission modulators on brain stimulation reward. |
2006 |
Psychopharmacology (Berl.) |
pmid:16953388
|
Mulder AM and Cravatt BF |
Endocannabinoid metabolism in the absence of fatty acid amide hydrolase (FAAH): discovery of phosphorylcholine derivatives of N-acyl ethanolamines. |
2006 |
Biochemistry |
pmid:16981687
|
Hong Z et al. |
Role of store-operated calcium channels and calcium sensitization in normoxic contraction of the ductus arteriosus. |
2006 |
Circulation |
pmid:16982938
|
Stefano GB and Salamon EJ |
Nitric oxide and anandamide in OMT research. |
2006 |
J Am Osteopath Assoc |
pmid:17122026
|
Lambert RC et al. |
Modulation of neuronal T-type calcium channels. |
2006 |
CNS Neurol Disord Drug Targets |
pmid:17168746
|
Kohro S et al. |
Anandamide absorption by direct hemoperfusion with polymixin B-immobilized fiber improves the prognosis and organ failure assessment score in patients with sepsis. |
2006 |
J Anesth |
pmid:16421670
|
Rawls SM et al. |
Role of TRPV1 and cannabinoid CB1 receptors in AM 404-evoked hypothermia in rats. |
2006 |
Pharmacol. Biochem. Behav. |
pmid:16647109
|
Parkkari T et al. |
Synthesis, cannabinoid receptor activity, and enzymatic stability of reversed amide derivatives of arachidonoyl ethanolamide. |
2006 |
Bioorg. Med. Chem. |
pmid:16644227
|
McFarland MJ et al. |
Detergent-resistant membrane microdomains in the disposition of the lipid signaling molecule anandamide. |
2006 |
AAPS J |
pmid:16584138
|
Giuliano M et al. |
Anandamide-induced apoptosis in Chang liver cells involves ceramide and JNK/AP-1 pathway. |
2006 |
Int. J. Mol. Med. |
pmid:16596265
|
Di Marzo M et al. |
Synthesis, conformational analysis and CB1 binding affinity of hairpin-like anandamide pseudopeptide mimetics. |
2006 |
J. Pept. Sci. |
pmid:16534762
|
Cobellis G et al. |
Endocannabinoid system in frog and rodent testis: type-1 cannabinoid receptor and fatty acid amide hydrolase activity in male germ cells. |
2006 |
Biol. Reprod. |
pmid:16611862
|
Solinas M et al. |
Anandamide administration alone and after inhibition of fatty acid amide hydrolase (FAAH) increases dopamine levels in the nucleus accumbens shell in rats. |
2006 |
J. Neurochem. |
pmid:16805835
|
Vinod KY et al. |
Effect of chronic ethanol exposure and its withdrawal on the endocannabinoid system. |
2006 |
Neurochem. Int. |
pmid:16822589
|
Ghasemi M et al. |
Effect of anandamide on nonadrenergic noncholinergic-mediated relaxation of rat corpus cavernosum. |
2006 |
Eur. J. Pharmacol. |
pmid:16824514
|
Wagner JA et al. |
2-Arachidonylglycerol acting on CB1 cannabinoid receptors mediates delayed cardioprotection induced by nitric oxide in rat isolated hearts. |
2006 |
J. Cardiovasc. Pharmacol. |
pmid:16775503
|
Bonechi C et al. |
Nuclear magnetic resonance for studying recognition processes between anandamide and cannabinoid receptors. |
2006 |
Eur J Med Chem |
pmid:16837109
|
Costa B et al. |
AM404, an inhibitor of anandamide uptake, prevents pain behaviour and modulates cytokine and apoptotic pathways in a rat model of neuropathic pain. |
2006 |
Br. J. Pharmacol. |
pmid:16770320
|
Felder CC et al. |
Cannabinoids biology: the search for new therapeutic targets. |
2006 |
Mol. Interv. |
pmid:16809476
|
Yeh JH et al. |
Effect of anandamide on cytosolic Ca(2+) levels and proliferation in canine renal tubular cells. |
2006 |
Basic Clin. Pharmacol. Toxicol. |
pmid:16623868
|
Laviolette SR and Grace AA |
The roles of cannabinoid and dopamine receptor systems in neural emotional learning circuits: implications for schizophrenia and addiction. |
2006 |
Cell. Mol. Life Sci. |
pmid:16699809
|
Sade H et al. |
Activation of large-conductance, Ca2+-activated K+ channels by cannabinoids. |
2006 |
Am. J. Physiol., Cell Physiol. |
pmid:16107501
|
Li J and Wang DH |
Differential mechanisms mediating depressor and diuretic effects of anandamide. |
2006 |
J. Hypertens. |
pmid:17053550
|
Krishtal O et al. |
The agonists for nociceptors are ubiquitous, but the modulators are specific: P2X receptors in the sensory neurons are modulated by cannabinoids. |
2006 |
Pflugers Arch. |
pmid:16741755
|
Wang Y et al. |
A novel scintillation proximity assay for fatty acid amide hydrolase compatible with inhibitor screening. |
2006 |
Anal. Biochem. |
pmid:16707086
|
Tzavara ET et al. |
Endocannabinoids activate transient receptor potential vanilloid 1 receptors to reduce hyperdopaminergia-related hyperactivity: therapeutic implications. |
2006 |
Biol. Psychiatry |
pmid:16199010
|
Schmidt A et al. |
Determination of the endocannabinoid anandamide in human plasma by high-performance liquid chromatography. |
2006 |
Biomed. Chromatogr. |
pmid:16189813
|
Bai X et al. |
TASK channel expression in human placenta and cytotrophoblast cells. |
2006 |
J. Soc. Gynecol. Investig. |
pmid:16378911
|
Hejazi N et al. |
Delta9-tetrahydrocannabinol and endogenous cannabinoid anandamide directly potentiate the function of glycine receptors. |
2006 |
Mol. Pharmacol. |
pmid:16332990
|
Bojesen IN and Hansen HS |
Effect of an unstirred layer on the membrane permeability of anandamide. |
2006 |
J. Lipid Res. |
pmid:16365480
|
D'Argenio G et al. |
Up-regulation of anandamide levels as an endogenous mechanism and a pharmacological strategy to limit colon inflammation. |
2006 |
FASEB J. |
pmid:16403786
|
Suplita RL et al. |
Endocannabinoids at the spinal level regulate, but do not mediate, nonopioid stress-induced analgesia. |
2006 |
Neuropharmacology |
pmid:16316669
|
Avelino A and Cruz F |
TRPV1 (vanilloid receptor) in the urinary tract: expression, function and clinical applications. |
2006 |
Naunyn Schmiedebergs Arch. Pharmacol. |
pmid:16721555
|
Murillo-Rodriguez E et al. |
Diurnal variation of arachidonoylethanolamine, palmitoylethanolamide and oleoylethanolamide in the brain of the rat. |
2006 |
Life Sci. |
pmid:16434061
|
Ligresti A et al. |
New potent and selective inhibitors of anandamide reuptake with antispastic activity in a mouse model of multiple sclerosis. |
2006 |
Br. J. Pharmacol. |
pmid:16284631
|
Bir LS and Ercan S |
Effects of intrathecal anandamide on somatosensory evoked responses in rats. |
2006 |
Exp. Neurol. |
pmid:16289169
|
Urbani P et al. |
New metabolically stable fatty acid amide ligands of cannabinoid receptors: Synthesis and receptor affinity studies. |
2006 |
Bioorg. Med. Chem. Lett. |
pmid:16213718
|
Lynch DL and Reggio PH |
Cannabinoid CB1 receptor recognition of endocannabinoids via the lipid bilayer: molecular dynamics simulations of CB1 transmembrane helix 6 and anandamide in a phospholipid bilayer. |
2006 Jul-Aug |
J. Comput. Aided Mol. Des. |
pmid:17106765
|
Dickason-Chesterfield AK et al. |
Pharmacological characterization of endocannabinoid transport and fatty acid amide hydrolase inhibitors. |
2006 Jul-Aug |
Cell. Mol. Neurobiol. |
pmid:16736384
|
Battista N et al. |
The endocannabinoid system in neurodegeneration. |
2006 Sep-Dec |
Ital. J. Biochem. |
pmid:17274532
|
Oka S et al. |
Depolarization-induced rapid generation of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, in rat brain synaptosomes. |
2007 |
J. Biochem. |
pmid:17339228
|
D'Argenio G et al. |
Overactivity of the intestinal endocannabinoid system in celiac disease and in methotrexate-treated rats. |
2007 |
J. Mol. Med. |
pmid:17396241
|
Holt S et al. |
Inhibition of fatty acid amide hydrolase, a key endocannabinoid metabolizing enzyme, by analogues of ibuprofen and indomethacin. |
2007 |
Eur. J. Pharmacol. |
pmid:17397826
|
Mahler SV et al. |
Endocannabinoid hedonic hotspot for sensory pleasure: anandamide in nucleus accumbens shell enhances 'liking' of a sweet reward. |
2007 |
Neuropsychopharmacology |
pmid:17406653
|
Kopczyńska B |
The contribution of VR1 and CB1 receptors and the role of the afferent vagal pathway in modelling of cardio-respiratory effects of anandamide in rats. |
2007 |
Life Sci. |
pmid:17379256
|
Ferrer B et al. |
Regulation of brain anandamide by acute administration of ethanol. |
2007 |
Biochem. J. |
pmid:17302558
|
Köfalvi A et al. |
Anandamide and NADA bi-directionally modulate presynaptic Ca2+ levels and transmitter release in the hippocampus. |
2007 |
Br. J. Pharmacol. |
pmid:17435795
|
Orliac ML et al. |
Increases in vanilloid TRPV1 receptor protein and CGRP content during endotoxemia in rats. |
2007 |
Eur. J. Pharmacol. |
pmid:17482593
|
Michalski CW et al. |
Cannabinoids ameliorate pain and reduce disease pathology in cerulein-induced acute pancreatitis. |
2007 |
Gastroenterology |
pmid:17484889
|
Ghasemi M et al. |
Role of the nitric oxide pathway and the endocannabinoid system in neurogenic relaxation of corpus cavernosum from biliary cirrhotic rats. |
2007 |
Br. J. Pharmacol. |
pmid:17486141
|
Borsani E et al. |
AM404 decreases Fos-immunoreactivity in the spinal cord in a model of inflammatory pain. |
2007 |
Brain Res. |
pmid:17459353
|
Sit SY et al. |
Novel inhibitors of fatty acid amide hydrolase. |
2007 |
Bioorg. Med. Chem. Lett. |
pmid:17459705
|
Lory P and Chemin J |
Towards the discovery of novel T-type calcium channel blockers. |
2007 |
Expert Opin. Ther. Targets |
pmid:17465728
|
Ryan D et al. |
Interactions of cannabidiol with endocannabinoid signalling in hippocampal tissue. |
2007 |
Eur. J. Neurosci. |
pmid:17419758
|
Béquet F et al. |
CB1 receptor-mediated control of the release of endocannabinoids (as assessed by microdialysis coupled with LC/MS) in the rat hypothalamus. |
2007 |
Eur. J. Neurosci. |
pmid:18052990
|
Rettori V et al. |
Endocannabinoids in TNF-alpha and ethanol actions. |
2007 |
Neuroimmunomodulation |
pmid:18073513
|
Jin XH et al. |
Discovery and characterization of a Ca2+-independent phosphatidylethanolamine N-acyltransferase generating the anandamide precursor and its congeners. |
2007 |
J. Biol. Chem. |
pmid:17158102
|
Rossi G et al. |
Follicle-stimulating hormone activates fatty acid amide hydrolase by protein kinase A and aromatase-dependent pathways in mouse primary Sertoli cells. |
2007 |
Endocrinology |
pmid:17110429
|
Cross-Mellor SK et al. |
Effects of the FAAH inhibitor, URB597, and anandamide on lithium-induced taste reactivity responses: a measure of nausea in the rat. |
2007 |
Psychopharmacology (Berl.) |
pmid:17111174
|
Ronco AM et al. |
Anandamide inhibits endothelin-1 production by human cultured endothelial cells: a new vascular action of this endocannabinoid. |
2007 |
Pharmacology |
pmid:17114903
|
Wheal AJ et al. |
Effects of chronic nitric oxide synthase inhibition on the cardiovascular responses to cannabinoids in vivo and in vitro. |
2007 |
Br. J. Pharmacol. |
pmid:17245361
|
Bátkai S et al. |
Decreased age-related cardiac dysfunction, myocardial nitrative stress, inflammatory gene expression, and apoptosis in mice lacking fatty acid amide hydrolase. |
2007 |
Am. J. Physiol. Heart Circ. Physiol. |
pmid:17434980
|
Harada N and Okajima K |
Effect of topical application of capsaicin and its related compounds on dermal insulin-like growth factor-I levels in mice and on facial skin elasticity in humans. |
2007 |
Growth Horm. IGF Res. |
pmid:17307377
|
Romero FA et al. |
Potent and selective alpha-ketoheterocycle-based inhibitors of the anandamide and oleamide catabolizing enzyme, fatty acid amide hydrolase. |
2007 |
J. Med. Chem. |
pmid:17279740
|
McCollum L et al. |
Anandamide-mediated CB1/CB2 cannabinoid receptor--independent nitric oxide production in rabbit aortic endothelial cells. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17379772
|
Wang Y et al. |
Endocannabinoid regulates blood pressure via activation of the transient receptor potential vanilloid type 1 in Wistar rats fed a high-salt diet. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17308041
|
Snider NT et al. |
Anandamide metabolism by human liver and kidney microsomal cytochrome p450 enzymes to form hydroxyeicosatetraenoic and epoxyeicosatrienoic acid ethanolamides. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17272674
|
Solinas M et al. |
The endogenous cannabinoid anandamide produces delta-9-tetrahydrocannabinol-like discriminative and neurochemical effects that are enhanced by inhibition of fatty acid amide hydrolase but not by inhibition of anandamide transport. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17210800
|
Wise LE et al. |
Assessment of anandamide's pharmacological effects in mice deficient of both fatty acid amide hydrolase and cannabinoid CB1 receptors. |
2007 |
Eur. J. Pharmacol. |
pmid:17217945
|
Hsu SS et al. |
Anandamide-induced Ca2+ elevation leading to p38 MAPK phosphorylation and subsequent cell death via apoptosis in human osteosarcoma cells. |
2007 |
Toxicology |
pmid:17222495
|
Harada N and Okajima K |
Inhibition of neutrophil activation by lafutidine, an H2-receptor antagonist, through enhancement of sensory neuron activation contributes to the reduction of stress-induced gastric mucosal injury in rats. |
2007 |
Dig. Dis. Sci. |
pmid:17211693
|
Pisanti S et al. |
Antiangiogenic activity of the endocannabinoid anandamide: correlation to its tumor-suppressor efficacy. |
2007 |
J. Cell. Physiol. |
pmid:17192847
|
Ekins S et al. |
Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors. |
2007 |
Drug Metab. Dispos. |
pmid:17194716
|
Malfitano AM et al. |
Arvanil and anandamide up-regulate CD36 expression in human peripheral blood mononuclear cells. |
2007 |
Immunol. Lett. |
pmid:17360047
|
Thomas KC et al. |
Transient receptor potential vanilloid 1 agonists cause endoplasmic reticulum stress and cell death in human lung cells. |
2007 |
J. Pharmacol. Exp. Ther. |
pmid:17332266
|