Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Authors Title Published Journal PubMed Link
Heyman E et al. Intense exercise increases circulating endocannabinoid and BDNF levels in humans--possible implications for reward and depression. 2012 Psychoneuroendocrinology pmid:22029953
Izumi Y and Zorumski CF NMDA receptors, mGluR5, and endocannabinoids are involved in a cascade leading to hippocampal long-term depression. 2012 Neuropsychopharmacology pmid:21993209
Malinowska B et al. Triphasic blood pressure responses to cannabinoids: do we understand the mechanism? 2012 Br. J. Pharmacol. pmid:22022923
Li Q et al. Effects of anandamide on potassium channels in rat ventricular myocytes: a suppression of I(to) and augmentation of K(ATP) channels. 2012 Am. J. Physiol., Cell Physiol. pmid:22173869
Jang Y et al. Axonal neuropathy-associated TRPV4 regulates neurotrophic factor-derived axonal growth. 2012 J. Biol. Chem. pmid:22187434
Marsicano G and Chaouloff F Moving bliss: a new anandamide transporter. 2012 Nat. Neurosci. pmid:22193249
Battista N et al. Abnormal anandamide metabolism in celiac disease. 2012 J. Nutr. Biochem. pmid:22209002
Schulte K et al. Cannabinoid CB1 receptor activation, pharmacological blockade, or genetic ablation affects the function of the muscarinic auto- and heteroreceptor. 2012 Naunyn Schmiedebergs Arch. Pharmacol. pmid:22215206
Wu X et al. Alteration of endocannabinoid system in human gliomas. 2012 J. Neurochem. pmid:22176552
Ritter JK et al. Production and actions of the anandamide metabolite prostamide E2 in the renal medulla. 2012 J. Pharmacol. Exp. Ther. pmid:22685343
Gebeh AK et al. Ectopic pregnancy is associated with high anandamide levels and aberrant expression of FAAH and CB1 in fallopian tubes. 2012 J. Clin. Endocrinol. Metab. pmid:22701012
Chianese R et al. Anandamide regulates the expression of GnRH1, GnRH2, and GnRH-Rs in frog testis. 2012 Am. J. Physiol. Endocrinol. Metab. pmid:22669247
Chicca A et al. The antinociceptive triterpene β-amyrin inhibits 2-arachidonoylglycerol (2-AG) hydrolysis without directly targeting cannabinoid receptors. 2012 Br. J. Pharmacol. pmid:22646533
Hernangómez M et al. CD200-CD200R1 interaction contributes to neuroprotective effects of anandamide on experimentally induced inflammation. 2012 Glia pmid:22653796
Tsumura M et al. TRPV1-mediated calcium signal couples with cannabinoid receptors and sodium-calcium exchangers in rat odontoblasts. 2012 Cell Calcium pmid:22656960
Méndez-Díaz M et al. The endocannabinoid system modulates the valence of the emotion associated to food ingestion. 2012 Addict Biol pmid:21182571
Berger WT et al. Targeting fatty acid binding protein (FABP) anandamide transporters - a novel strategy for development of anti-inflammatory and anti-nociceptive drugs. 2012 PLoS ONE pmid:23236415
Butti E et al. Subventricular zone neural progenitors protect striatal neurons from glutamatergic excitotoxicity. 2012 Brain pmid:23008234
Roa-Coria JE et al. N-(4-Methoxy-2-nitrophenyl)hexadecanamide, a palmitoylethanolamide analogue, reduces formalin-induced nociception. 2012 Life Sci. pmid:23069585
Schmidt W et al. Cannabinoid receptor subtypes 1 and 2 mediate long-lasting neuroprotection and improve motor behavior deficits after transient focal cerebral ischemia. 2012 Neuroscience pmid:23069763
Pastuhov SI et al. Endocannabinoid-Goα signalling inhibits axon regeneration in Caenorhabditis elegans by antagonizing Gqα-PKC-JNK signalling. 2012 Nat Commun pmid:23072806
Fu J et al. A catalytically silent FAAH-1 variant drives anandamide transport in neurons. 2012 Nat. Neurosci. pmid:22101642
Feuerecker M et al. Effects of exercise stress on the endocannabinoid system in humans under field conditions. 2012 Eur. J. Appl. Physiol. pmid:22101870
Reyes-Cabello C et al. Effects of the anandamide uptake blocker AM404 on food intake depend on feeding status and route of administration. 2012 Pharmacol. Biochem. Behav. pmid:22133635
Sun Y et al. Cannabinoid receptor activation disrupts the internal structure of hippocampal sharp wave-ripple complexes. 2012 J. Pharmacol. Sci. pmid:22293299
Goonawardena AV et al. Pharmacological elevation of anandamide impairs short-term memory by altering the neurophysiology in the hippocampus. 2011 Oct-Nov Neuropharmacology pmid:21767554
Romero TR et al. The neuronal NO synthase participation in the peripheral antinociception mechanism induced by several analgesic drugs. 2011 Nitric Oxide pmid:21875681
Dean C Cannabinoid and GABA modulation of sympathetic nerve activity and blood pressure in the dorsal periaqueductal gray of the rat. 2011 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:21940402
Long JZ et al. An anatomical and temporal portrait of physiological substrates for fatty acid amide hydrolase. 2011 J. Lipid Res. pmid:21097653
Hofmann ME et al. Cannabinoid receptor agonists potentiate action potential-independent release of GABA in the dentate gyrus through a CB1 receptor-independent mechanism. 2011 J. Physiol. (Lond.) pmid:21646412
Martín-Couce L et al. Development of endocannabinoid-based chemical probes for the study of cannabinoid receptors. 2011 J. Med. Chem. pmid:21675776
Romani R et al. Anandamide and its congeners inhibit human plasma butyrylcholinesterase. Possible new roles for these endocannabinoids? 2011 Biochimie pmid:21664223
Khanna IK and Alexander CW Fatty acid amide hydrolase inhibitors--progress and potential. 2011 CNS Neurol Disord Drug Targets pmid:21631410
Busquets-Garcia A et al. Differential role of anandamide and 2-arachidonoylglycerol in memory and anxiety-like responses. 2011 Biol. Psychiatry pmid:21684528
Ishiguro H et al. Functional polymorphism in the GPR55 gene is associated with anorexia nervosa. 2011 Synapse pmid:20506567
Hollis JH et al. The endocannabinoid arachidonylethanolamide attenuates aspects of lipopolysaccharide-induced changes in energy intake, energy expenditure and hypothalamic Fos expression. 2011 J. Neuroimmunol. pmid:21262543
Zschenderlein C et al. Capsaicin-induced changes in LTP in the lateral amygdala are mediated by TRPV1. 2011 PLoS ONE pmid:21249195
Garami A et al. Thermoregulatory phenotype of the Trpv1 knockout mouse: thermoeffector dysbalance with hyperkinesis. 2011 J. Neurosci. pmid:21289181
Wang W et al. Enhancement of apamin-sensitive medium afterhyperpolarization current by anandamide and its role in excitability control in cultured hippocampal neurons. 2011 Neuropharmacology pmid:21272594
Reis GM et al. Endogenous cannabinoid receptor agonist anandamide induces peripheral antinociception by activation of ATP-sensitive K+ channels. 2011 Life Sci. pmid:21277864
Kawahara H et al. Inhibition of fatty acid amide hydrolase unmasks CB1 receptor and TRPV1 channel-mediated modulation of glutamatergic synaptic transmission in midbrain periaqueductal grey. 2011 Br. J. Pharmacol. pmid:21175570
Taylor AH et al. Modulation of the endocannabinoid system in viable and non-viable first trimester pregnancies by pregnancy-related hormones. 2011 Reprod. Biol. Endocrinol. pmid:22126420
Brizzi A et al. Resorcinol-sn-glycerol derivatives: novel 2-arachidonoylglycerol mimetics endowed with high affinity and selectivity for cannabinoid type 1 receptor. 2011 J. Med. Chem. pmid:22044209
Hamtiaux L et al. Increasing antiproliferative properties of endocannabinoids in N1E-115 neuroblastoma cells through inhibition of their metabolism. 2011 PLoS ONE pmid:22046372
Lin QS et al. Hippocampal endocannabinoids play an important role in induction of long-term potentiation and regulation of contextual fear memory formation. 2011 Brain Res. Bull. pmid:21801815
Tsuboi K et al. Enzymatic formation of N-acylethanolamines from N-acylethanolamine plasmalogen through N-acylphosphatidylethanolamine-hydrolyzing phospholipase D-dependent and -independent pathways. 2011 Biochim. Biophys. Acta pmid:21801852
Chianese R et al. Anandamide modulates the expression of GnRH-II and GnRHRs in frog, Rana esculenta, diencephalon. 2011 Gen. Comp. Endocrinol. pmid:21802420
Clugston RD et al. Altered hepatic lipid metabolism in C57BL/6 mice fed alcohol: a targeted lipidomic and gene expression study. 2011 J. Lipid Res. pmid:21856784
Dollery C Investigative clinical pharmacology. 2011 Clin. Pharmacol. Ther. pmid:21862965
Khasabova IA et al. Increasing 2-arachidonoyl glycerol signaling in the periphery attenuates mechanical hyperalgesia in a model of bone cancer pain. 2011 Pharmacol. Res. pmid:21440630