Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Authors Title Published Journal PubMed Link
Derkinderen P et al. Regulation of a neuronal form of focal adhesion kinase by anandamide. 1996 Science pmid:8781236
Shimasue K et al. Effects of anandamide and arachidonic acid on specific binding of (+) -PN200-110, diltiazem and (-) -desmethoxyverapamil to L-type Ca2+ channel. 1996 Eur. J. Pharmacol. pmid:8904088
Sugiura T et al. Enzymatic synthesis of anandamide, an endogenous cannabinoid receptor ligand, through N-acylphosphatidylethanolamine pathway in testis: involvement of Ca(2+)-dependent transacylase and phosphodiesterase activities. 1996 Biochem. Biophys. Res. Commun. pmid:8573114
Jarho P et al. Hydroxypropyl-beta-cyclodextrin increases aqueous solubility and stability of anandamide. 1996 Life Sci. pmid:8602110
Skaper SD et al. The ALIAmide palmitoylethanolamide and cannabinoids, but not anandamide, are protective in a delayed postglutamate paradigm of excitotoxic death in cerebellar granule neurons. 1996 Proc. Natl. Acad. Sci. U.S.A. pmid:8633002
Wise ML et al. Synthesis and cannabinoid receptor binding activity of conjugated triene anandamide, a novel eicosanoid. 1996 Experientia pmid:8575565
Pan X et al. Rat brain cannabinoid receptor modulates N-type Ca2+ channels in a neuronal expression system. 1996 Mol. Pharmacol. pmid:8609900
Fride E and Mechoulam R Developmental aspects of anandamide: ontogeny of response and prenatal exposure. 1996 Psychoneuroendocrinology pmid:8774060
Shivachar AC et al. Anandamide- and delta9-tetrahydrocannabinol-evoked arachidonic acid mobilization and blockade by SR141716A [N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4 -methyl-1H-pyrazole-3-carboximide hydrochloride]. 1996 Biochem. Pharmacol. pmid:8615904
Ishac EJ et al. Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB1 receptors on peripheral sympathetic nerves. 1996 Br. J. Pharmacol. pmid:8864538
Fride E and Mechoulam R Ontogenetic development of the response to anandamide and delta 9-tetrahydrocannabinol in mice. 1996 Brain Res. Dev. Brain Res. pmid:8873985
Sugiura T et al. 2-Arachidonoylglycerol, a putative endogenous cannabinoid receptor ligand, induces rapid, transient elevation of intracellular free Ca2+ in neuroblastoma x glioma hybrid NG108-15 cells. 1996 Biochem. Biophys. Res. Commun. pmid:8954083
Stein EA et al. Physiological and behavioural effects of the endogenous cannabinoid, arachidonylethanolamide (anandamide), in the rat. 1996 Br. J. Pharmacol. pmid:8872363
James JS Marijuana and chocolate. 1996 AIDS Treat News pmid:11363932
Thomas BF et al. Structure-activity analysis of anandamide analogs: relationship to a cannabinoid pharmacophore. 1996 J. Med. Chem. pmid:8558515
Berdyshev EV et al. Anandamide--a new look on fatty acid ethanolamides. 1996 J Lipid Mediat Cell Signal pmid:9029374
Randall MD et al. An endogenous cannabinoid as an endothelium-derived vasorelaxant. 1996 Biochem. Biophys. Res. Commun. pmid:8954092
Paria BC et al. The uterus is a potential site for anandamide synthesis and hydrolysis: differential profiles of anandamide synthase and hydrolase activities in the mouse uterus during the periimplantation period. 1996 Mol. Reprod. Dev. pmid:8914076
Khanolkar AD et al. Head group analogs of arachidonylethanolamide, the endogenous cannabinoid ligand. 1996 J. Med. Chem. pmid:8893848
Langstein J et al. cis-9,10-octadecenoamide, an endogenous sleep-inducing CNS compound, inhibits lymphocyte proliferation. 1996 Jul-Aug Res. Immunol. pmid:8903105
Thomas EA et al. Fatty acid amide hydrolase, the degradative enzyme for anandamide and oleamide, has selective distribution in neurons within the rat central nervous system. 1997 J. Neurosci. Res. pmid:9452020
Bisogno T et al. The sleep inducing factor oleamide is produced by mouse neuroblastoma cells. 1997 Biochem. Biophys. Res. Commun. pmid:9344854
Sasaki T and Chang MC N-arachidonylethanolamine (anandamide) formation from N-arachidonylphosphatidylethanolamine in rat brain membranes. 1997 Life Sci. pmid:9365227
Randall MD and Kendall DA Involvement of a cannabinoid in endothelium-derived hyperpolarizing factor-mediated coronary vasorelaxation. 1997 Eur. J. Pharmacol. pmid:9369375
Burkey TH et al. Relative efficacies of cannabinoid CB1 receptor agonists in the mouse brain. 1997 Eur. J. Pharmacol. pmid:9384246
Calignano A et al. Potentiation of anandamide hypotension by the transport inhibitor, AM404. 1997 Eur. J. Pharmacol. pmid:9389389
Seltzman HH et al. Synthesis and pharmacological comparison of dimethylheptyl and pentyl analogs of anandamide. 1997 J. Med. Chem. pmid:9357529
Thumser AE et al. A fluorescence displacement assay for the measurement of arachidonoyl ethanolamide (anandamide) and oleoyl amide (octadecenoamide) hydrolysis. 1997 Biochem. Pharmacol. pmid:9065749
Ryan WJ et al. Potent anandamide analogs: the effect of changing the length and branching of the end pentyl chain. 1997 J. Med. Chem. pmid:9357528
Bisogno T et al. Biosynthesis, release and degradation of the novel endogenous cannabimimetic metabolite 2-arachidonoylglycerol in mouse neuroblastoma cells. 1997 Biochem. J. pmid:9065792
De Petrocellis L et al. Novel inhibitors of brain, neuronal, and basophilic anandamide amidohydrolase. 1997 Biochem. Biophys. Res. Commun. pmid:9070224
Deutsch DG et al. Fatty acid sulfonyl fluorides inhibit anandamide metabolism and bind to the cannabinoid receptor. 1997 Biochem. Biophys. Res. Commun. pmid:9070252
Lake KD et al. Cardiovascular effects of anandamide in anesthetized and conscious normotensive and hypertensive rats. 1997 Hypertension pmid:9149688
Bisogno T et al. Occurrence and metabolism of anandamide and related acyl-ethanolamides in ovaries of the sea urchin Paracentrotus lividus. 1997 Biochim. Biophys. Acta pmid:9150253
Stefano GB et al. Identification and characterization of the leech CNS cannabinoid receptor: coupling to nitric oxide release. 1997 Brain Res. pmid:9125406
Mechoulam R Todd's achievement. 1997 Nature pmid:9126725
Koga D et al. Liquid chromatographic-atmospheric pressure chemical ionization mass spectrometric determination of anandamide and its analogs in rat brain and peripheral tissues. 1997 J. Chromatogr. B Biomed. Sci. Appl. pmid:9106024
Schmid PC et al. Changes in anandamide levels in mouse uterus are associated with uterine receptivity for embryo implantation. 1997 Proc. Natl. Acad. Sci. U.S.A. pmid:9108127
Cadas H et al. Occurrence and biosynthesis of endogenous cannabinoid precursor, N-arachidonoyl phosphatidylethanolamine, in rat brain. 1997 J. Neurosci. pmid:9006968
Bisogno T et al. Biosynthesis, uptake, and degradation of anandamide and palmitoylethanolamide in leukocytes. 1997 J. Biol. Chem. pmid:9013571
Fowler CJ et al. Ibuprofen inhibits the metabolism of the endogenous cannabimimetic agent anandamide. 1997 Pharmacol. Toxicol. pmid:9060042
Hillard CJ and Campbell WB Biochemistry and pharmacology of arachidonylethanolamide, a putative endogenous cannabinoid. 1997 J. Lipid Res. pmid:9458263
Plane F et al. Evidence that anandamide and EDHF act via different mechanisms in rat isolated mesenteric arteries. 1997 Br. J. Pharmacol. pmid:9283682
Beltramo M et al. Functional role of high-affinity anandamide transport, as revealed by selective inhibition. 1997 Science pmid:9262477
Valk P et al. Anandamide, a natural ligand for the peripheral cannabinoid receptor is a novel synergistic growth factor for hematopoietic cells. 1997 Blood pmid:9269762
Twitchell W et al. Cannabinoids inhibit N- and P/Q-type calcium channels in cultured rat hippocampal neurons. 1997 J. Neurophysiol. pmid:9242259
Matsuda S et al. Metabolism of anandamide, an endogenous cannabinoid receptor ligand, in porcine ocular tissues. 1997 Exp. Eye Res. pmid:9245900
Wagner JA et al. Activation of peripheral CB1 cannabinoid receptors in haemorrhagic shock. 1997 Nature pmid:9394002
Compton DR and Martin BR The effect of the enzyme inhibitor phenylmethylsulfonyl fluoride on the pharmacological effect of anandamide in the mouse model of cannabimimetic activity. 1997 J. Pharmacol. Exp. Ther. pmid:9399986
Stella N et al. A second endogenous cannabinoid that modulates long-term potentiation. 1997 Nature pmid:9285589