Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

Cross Reference

Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Neuralgia D009437 28 associated lipids
Fibromyalgia D005356 4 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Intestinal Pseudo-Obstruction D007418 5 associated lipids
Mycoses D009181 18 associated lipids
Bulimia D002032 3 associated lipids
Sleep Deprivation D012892 5 associated lipids
Urinary Incontinence D014549 4 associated lipids
Per page 10 20 50 100 | Total 105

PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

Download all related citations
Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Panagis G et al. Behavioral pharmacology of cannabinoids with a focus on preclinical models for studying reinforcing and dependence-producing properties. 2008 Curr Drug Abuse Rev pmid:19630731
Gorzalka BB et al. Endocannabinoid modulation of male rat sexual behavior. 2008 Psychopharmacology (Berl.) pmid:17694389
Wise LE et al. Evaluation of fatty acid amides in the carrageenan-induced paw edema model. 2008 Neuropharmacology pmid:17675189
Terry G et al. Positron emission tomography imaging using an inverse agonist radioligand to assess cannabinoid CB1 receptors in rodents. 2008 Neuroimage pmid:18456516
Yang Z et al. Subunit-specific modulation of glycine receptors by cannabinoids and N-arachidonyl-glycine. 2008 Biochem. Pharmacol. pmid:18755158
Murillo-Rodríguez E et al. The anandamide membrane transporter inhibitor, VDM-11, modulates sleep and c-Fos expression in the rat brain. 2008 Neuroscience pmid:18822353
Woo DH et al. Direct activation of transient receptor potential vanilloid 1(TRPV1) by diacylglycerol (DAG). 2008 Mol Pain pmid:18826653
Lisboa SF et al. Activation of cannabinoid CB1 receptors in the dorsolateral periaqueductal gray induces anxiolytic effects in rats submitted to the Vogel conflict test. 2008 Eur. J. Pharmacol. pmid:18691568
Currie S et al. IP(3)R-mediated Ca(2+) release is modulated by anandamide in isolated cardiac nuclei. 2008 J. Mol. Cell. Cardiol. pmid:18692061
Bjursell M et al. Acutely reduced locomotor activity is a major contributor to Western diet-induced obesity in mice. 2008 Am. J. Physiol. Endocrinol. Metab. pmid:18029443
Williams MA et al. The group IV afferent neuron expresses multiple receptor alterations in cardiomyopathyic rats: evidence at the cannabinoid CB1 receptor. 2008 J. Physiol. (Lond.) pmid:18063665
Thiemann G et al. The role of the CB1 cannabinoid receptor and its endogenous ligands, anandamide and 2-arachidonoylglycerol, in amphetamine-induced behavioural sensitization. 2008 Behav. Brain Res. pmid:17988751
Correa F et al. Anandamide inhibits IL-12p40 production by acting on the promoter repressor element GA-12: possible involvement of the COX-2 metabolite prostamide E(2). 2008 Biochem. J. pmid:17961121
Taylor AH et al. The role of the endocannabinoid system in gametogenesis, implantation and early pregnancy. 2007 Sep-Oct Hum. Reprod. Update pmid:17584820
Sakamoto Y et al. Clinical responses and improvement of some laboratory parameters following polymyxin B-immobilized fiber treatment in septic shock. 2007 Sep-Oct ASAIO J. pmid:17885340
Oka S et al. Depolarization-induced rapid generation of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, in rat brain synaptosomes. 2007 J. Biochem. pmid:17339228
D'Argenio G et al. Overactivity of the intestinal endocannabinoid system in celiac disease and in methotrexate-treated rats. 2007 J. Mol. Med. pmid:17396241
Holt S et al. Inhibition of fatty acid amide hydrolase, a key endocannabinoid metabolizing enzyme, by analogues of ibuprofen and indomethacin. 2007 Eur. J. Pharmacol. pmid:17397826
Mahler SV et al. Endocannabinoid hedonic hotspot for sensory pleasure: anandamide in nucleus accumbens shell enhances 'liking' of a sweet reward. 2007 Neuropsychopharmacology pmid:17406653
Kopczyńska B The contribution of VR1 and CB1 receptors and the role of the afferent vagal pathway in modelling of cardio-respiratory effects of anandamide in rats. 2007 Life Sci. pmid:17379256
Ferrer B et al. Regulation of brain anandamide by acute administration of ethanol. 2007 Biochem. J. pmid:17302558
Naidu PS et al. Evaluation of fatty acid amide hydrolase inhibition in murine models of emotionality. 2007 Psychopharmacology (Berl.) pmid:17279376
Sun Y et al. Cannabinoid activation of PPAR alpha; a novel neuroprotective mechanism. 2007 Br. J. Pharmacol. pmid:17906680
Rubio M et al. Short-term exposure to alcohol in rats affects brain levels of anandamide, other N-acylethanolamines and 2-arachidonoyl-glycerol. 2007 Neurosci. Lett. pmid:17574742
Ryberg E et al. The orphan receptor GPR55 is a novel cannabinoid receptor. 2007 Br. J. Pharmacol. pmid:17876302
Mulè F et al. Evidence for a modulatory role of cannabinoids on the excitatory NANC neurotransmission in mouse colon. 2007 Pharmacol. Res. pmid:17574859
Karsak M et al. Attenuation of allergic contact dermatitis through the endocannabinoid system. 2007 Science pmid:17556587
Bátkai S et al. Endocannabinoids acting at CB1 receptors mediate the cardiac contractile dysfunction in vivo in cirrhotic rats. 2007 Am. J. Physiol. Heart Circ. Physiol. pmid:17557913
Köfalvi A et al. Anandamide and NADA bi-directionally modulate presynaptic Ca2+ levels and transmitter release in the hippocampus. 2007 Br. J. Pharmacol. pmid:17435795
Williams J et al. Quantitative method for the profiling of the endocannabinoid metabolome by LC-atmospheric pressure chemical ionization-MS. 2007 Anal. Chem. pmid:17600384
Esposito G et al. Opposing control of cannabinoid receptor stimulation on amyloid-beta-induced reactive gliosis: in vitro and in vivo evidence. 2007 J. Pharmacol. Exp. Ther. pmid:17545311
Karanian DA et al. Endocannabinoid enhancement protects against kainic acid-induced seizures and associated brain damage. 2007 J. Pharmacol. Exp. Ther. pmid:17545313
Velenovská M and Fisar Z Effect of cannabinoids on platelet serotonin uptake. 2007 Addict Biol pmid:17508987
Brizzi A et al. Design, synthesis, binding, and molecular modeling studies of new potent ligands of cannabinoid receptors. 2007 Bioorg. Med. Chem. pmid:17561406
Hill MN et al. Electroconvulsive shock treatment differentially modulates cortical and subcortical endocannabinoid activity. 2007 J. Neurochem. pmid:17561935
Leweke FM et al. Anandamide levels in cerebrospinal fluid of first-episode schizophrenic patients: impact of cannabis use. 2007 Schizophr. Res. pmid:17566707
Ali AB Presynaptic Inhibition of GABAA receptor-mediated unitary IPSPs by cannabinoid receptors at synapses between CCK-positive interneurons in rat hippocampus. 2007 J. Neurophysiol. pmid:17567776
Fischbach T et al. Effects of anandamide and noxious heat on intracellular calcium concentration in nociceptive drg neurons of rats. 2007 J. Neurophysiol. pmid:17581853
Orliac ML et al. Increases in vanilloid TRPV1 receptor protein and CGRP content during endotoxemia in rats. 2007 Eur. J. Pharmacol. pmid:17482593
Michalski CW et al. Cannabinoids ameliorate pain and reduce disease pathology in cerulein-induced acute pancreatitis. 2007 Gastroenterology pmid:17484889
Ghasemi M et al. Role of the nitric oxide pathway and the endocannabinoid system in neurogenic relaxation of corpus cavernosum from biliary cirrhotic rats. 2007 Br. J. Pharmacol. pmid:17486141
Borsani E et al. AM404 decreases Fos-immunoreactivity in the spinal cord in a model of inflammatory pain. 2007 Brain Res. pmid:17459353
Sit SY et al. Novel inhibitors of fatty acid amide hydrolase. 2007 Bioorg. Med. Chem. Lett. pmid:17459705
Lory P and Chemin J Towards the discovery of novel T-type calcium channel blockers. 2007 Expert Opin. Ther. Targets pmid:17465728
Ryan D et al. Interactions of cannabidiol with endocannabinoid signalling in hippocampal tissue. 2007 Eur. J. Neurosci. pmid:17419758
Gonthier MP et al. Identification of endocannabinoids and related compounds in human fat cells. 2007 Obesity (Silver Spring) pmid:17426318
Raduner S et al. Self-assembling cannabinomimetics: supramolecular structures of N-alkyl amides. 2007 J. Nat. Prod. pmid:17497806
Wang Y and Wang DH Neural control of blood pressure: focusing on capsaicin-sensitive sensory nerves. 2007 Cardiovasc Hematol Disord Drug Targets pmid:17346127
Basavarajappa BS Critical enzymes involved in endocannabinoid metabolism. 2007 Protein Pept. Lett. pmid:17346227
Jia Y and Lee LY Role of TRPV receptors in respiratory diseases. 2007 Biochim. Biophys. Acta pmid:17346945
Solinas M et al. Nicotinic facilitation of delta9-tetrahydrocannabinol discrimination involves endogenous anandamide. 2007 J. Pharmacol. Exp. Ther. pmid:17351107
Centonze D et al. The endocannabinoid system is dysregulated in multiple sclerosis and in experimental autoimmune encephalomyelitis. 2007 Brain pmid:17626034
Spivak CE et al. The endocannabinoid anandamide inhibits the function of alpha4beta2 nicotinic acetylcholine receptors. 2007 Mol. Pharmacol. pmid:17628012
Thors L et al. Inhibition of the cellular uptake of anandamide by genistein and its analogue daidzein in cells with different levels of fatty acid amide hydrolase-driven uptake. 2007 Br. J. Pharmacol. pmid:17676056
Oz M et al. The endogenous cannabinoid anandamide inhibits cromakalim-activated K+ currents in follicle-enclosed Xenopus oocytes. 2007 J. Pharmacol. Exp. Ther. pmid:17682128
Mulè F et al. Involvement of CB1 and CB2 receptors in the modulation of cholinergic neurotransmission in mouse gastric preparations. 2007 Pharmacol. Res. pmid:17656103
Iuvone T et al. Cannabinoid CB1 receptor stimulation affords neuroprotection in MPTP-induced neurotoxicity by attenuating S100B up-regulation in vitro. 2007 J. Mol. Med. pmid:17639288
Béquet F et al. CB1 receptor-mediated control of the release of endocannabinoids (as assessed by microdialysis coupled with LC/MS) in the rat hypothalamus. 2007 Eur. J. Neurosci. pmid:18052990
Rettori V et al. Endocannabinoids in TNF-alpha and ethanol actions. 2007 Neuroimmunomodulation pmid:18073513
Akerman S et al. Cannabinoid (CB1) receptor activation inhibits trigeminovascular neurons. 2007 J. Pharmacol. Exp. Ther. pmid:17018694
Shimozawa N et al. Estrogen and isoflavone attenuate stress-induced gastric mucosal injury by inhibiting decreases in gastric tissue levels of CGRP in ovariectomized rats. 2007 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:17023553
Varvel SA et al. Inhibition of fatty-acid amide hydrolase accelerates acquisition and extinction rates in a spatial memory task. 2007 Neuropsychopharmacology pmid:17047668
Yang YY et al. Role of Ca2+-dependent potassium channels in in vitro anandamide-mediated mesenteric vasorelaxation in rats with biliary cirrhosis. 2007 Liver Int. pmid:17845532
Ghasemi M et al. Anandamide improves the impaired nitric oxide-mediated neurogenic relaxation of the corpus cavernosum in diabetic rats: involvement of cannabinoid CB1 and vanilloid VR1 receptors. 2007 BJU Int. pmid:17850365
Cisneros JA et al. Structure-activity relationship of a series of inhibitors of monoacylglycerol hydrolysis--comparison with effects upon fatty acid amide hydrolase. 2007 J. Med. Chem. pmid:17764163
Evans RM et al. Chronic exposure of sensory neurones to increased levels of nerve growth factor modulates CB1/TRPV1 receptor crosstalk. 2007 Br. J. Pharmacol. pmid:17700720
Wheal AJ et al. Cardiovascular effects of cannabinoids in conscious spontaneously hypertensive rats. 2007 Br. J. Pharmacol. pmid:17700721
Jin XH et al. Discovery and characterization of a Ca2+-independent phosphatidylethanolamine N-acyltransferase generating the anandamide precursor and its congeners. 2007 J. Biol. Chem. pmid:17158102
Rossi G et al. Follicle-stimulating hormone activates fatty acid amide hydrolase by protein kinase A and aromatase-dependent pathways in mouse primary Sertoli cells. 2007 Endocrinology pmid:17110429
Cross-Mellor SK et al. Effects of the FAAH inhibitor, URB597, and anandamide on lithium-induced taste reactivity responses: a measure of nausea in the rat. 2007 Psychopharmacology (Berl.) pmid:17111174
Ronco AM et al. Anandamide inhibits endothelin-1 production by human cultured endothelial cells: a new vascular action of this endocannabinoid. 2007 Pharmacology pmid:17114903
Ho WS and Randall MD Endothelium-dependent metabolism by endocannabinoid hydrolases and cyclooxygenases limits vasorelaxation to anandamide and 2-arachidonoylglycerol. 2007 Br. J. Pharmacol. pmid:17245358
Wheal AJ et al. Effects of chronic nitric oxide synthase inhibition on the cardiovascular responses to cannabinoids in vivo and in vitro. 2007 Br. J. Pharmacol. pmid:17245361
Bátkai S et al. Decreased age-related cardiac dysfunction, myocardial nitrative stress, inflammatory gene expression, and apoptosis in mice lacking fatty acid amide hydrolase. 2007 Am. J. Physiol. Heart Circ. Physiol. pmid:17434980
Harada N and Okajima K Effect of topical application of capsaicin and its related compounds on dermal insulin-like growth factor-I levels in mice and on facial skin elasticity in humans. 2007 Growth Horm. IGF Res. pmid:17307377
Romero FA et al. Potent and selective alpha-ketoheterocycle-based inhibitors of the anandamide and oleamide catabolizing enzyme, fatty acid amide hydrolase. 2007 J. Med. Chem. pmid:17279740
McCollum L et al. Anandamide-mediated CB1/CB2 cannabinoid receptor--independent nitric oxide production in rabbit aortic endothelial cells. 2007 J. Pharmacol. Exp. Ther. pmid:17379772
Wang Y et al. Endocannabinoid regulates blood pressure via activation of the transient receptor potential vanilloid type 1 in Wistar rats fed a high-salt diet. 2007 J. Pharmacol. Exp. Ther. pmid:17308041
Nucci C et al. Involvement of the endocannabinoid system in retinal damage after high intraocular pressure-induced ischemia in rats. 2007 Invest. Ophthalmol. Vis. Sci. pmid:17591864
Snider NT et al. Anandamide metabolism by human liver and kidney microsomal cytochrome p450 enzymes to form hydroxyeicosatetraenoic and epoxyeicosatrienoic acid ethanolamides. 2007 J. Pharmacol. Exp. Ther. pmid:17272674
Matta JA et al. TRPV1 is a novel target for omega-3 polyunsaturated fatty acids. 2007 J. Physiol. (Lond.) pmid:17038422
Solinas M et al. The endogenous cannabinoid anandamide produces delta-9-tetrahydrocannabinol-like discriminative and neurochemical effects that are enhanced by inhibition of fatty acid amide hydrolase but not by inhibition of anandamide transport. 2007 J. Pharmacol. Exp. Ther. pmid:17210800
Wise LE et al. Assessment of anandamide's pharmacological effects in mice deficient of both fatty acid amide hydrolase and cannabinoid CB1 receptors. 2007 Eur. J. Pharmacol. pmid:17217945
Hsu SS et al. Anandamide-induced Ca2+ elevation leading to p38 MAPK phosphorylation and subsequent cell death via apoptosis in human osteosarcoma cells. 2007 Toxicology pmid:17222495
Harada N and Okajima K Inhibition of neutrophil activation by lafutidine, an H2-receptor antagonist, through enhancement of sensory neuron activation contributes to the reduction of stress-induced gastric mucosal injury in rats. 2007 Dig. Dis. Sci. pmid:17211693
Pisanti S et al. Antiangiogenic activity of the endocannabinoid anandamide: correlation to its tumor-suppressor efficacy. 2007 J. Cell. Physiol. pmid:17192847
Ekins S et al. Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors. 2007 Drug Metab. Dispos. pmid:17194716
Schreiber D et al. Determination of anandamide and other fatty acyl ethanolamides in human serum by electrospray tandem mass spectrometry. 2007 Anal. Biochem. pmid:17196922
Kreutz S et al. Cannabinoids and neuronal damage: differential effects of THC, AEA and 2-AG on activated microglial cells and degenerating neurons in excitotoxically lesioned rat organotypic hippocampal slice cultures. 2007 Exp. Neurol. pmid:17010339
Ortar G et al. New N-arachidonoylserotonin analogues with potential "dual" mechanism of action against pain. 2007 J. Med. Chem. pmid:18027904
Malfitano AM et al. Arvanil and anandamide up-regulate CD36 expression in human peripheral blood mononuclear cells. 2007 Immunol. Lett. pmid:17360047
Degenhardt BF et al. Role of osteopathic manipulative treatment in altering pain biomarkers: a pilot study. 2007 J Am Osteopath Assoc pmid:17908831
Xu H et al. Functional effects of nonsynonymous polymorphisms in the human TRPV1 gene. 2007 Am. J. Physiol. Renal Physiol. pmid:17913835
Athanasiou A et al. Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. 2007 Biochem. Biophys. Res. Commun. pmid:17931597
Morgese MG et al. Anti-dyskinetic effects of cannabinoids in a rat model of Parkinson's disease: role of CB(1) and TRPV1 receptors. 2007 Exp. Neurol. pmid:17900568
Hillard CJ et al. Studies of anandamide accumulation inhibitors in cerebellar granule neurons: comparison to inhibition of fatty acid amide hydrolase. 2007 J. Mol. Neurosci. pmid:17901541
Opitz CA et al. Production of the endocannabinoids anandamide and 2-arachidonoylglycerol by endothelial progenitor cells. 2007 FEBS Lett. pmid:17904123
Romano MR and Lograno MD Evidence for the involvement of cannabinoid CB1 receptors in the bimatoprost-induced contractions on the human isolated ciliary muscle. 2007 Invest. Ophthalmol. Vis. Sci. pmid:17652738
Bentzen PJ and Lang F Effect of anandamide on erythrocyte survival. 2007 Cell. Physiol. Biochem. pmid:17975305
Thomas KC et al. Transient receptor potential vanilloid 1 agonists cause endoplasmic reticulum stress and cell death in human lung cells. 2007 J. Pharmacol. Exp. Ther. pmid:17332266