Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Neuralgia D009437 28 associated lipids
Fibromyalgia D005356 4 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Intestinal Pseudo-Obstruction D007418 5 associated lipids
Mycoses D009181 18 associated lipids
Bulimia D002032 3 associated lipids
Sleep Deprivation D012892 5 associated lipids
Urinary Incontinence D014549 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Okine BN et al. Lack of effect of chronic pre-treatment with the FAAH inhibitor URB597 on inflammatory pain behaviour: evidence for plastic changes in the endocannabinoid system. 2012 Br. J. Pharmacol. pmid:22595021
Miyashita K et al. Anandamide induces matrix metalloproteinase-2 production through cannabinoid-1 receptor and transient receptor potential vanilloid-1 in human dental pulp cells in culture. 2012 J Endod pmid:22595113
Vinod KY et al. Dysfunction in fatty acid amide hydrolase is associated with depressive-like behavior in Wistar Kyoto rats. 2012 PLoS ONE pmid:22606285
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Wheal AJ et al. Hydrogen peroxide as a mediator of vasorelaxation evoked by N-oleoylethanolamine and anandamide in rat small mesenteric arteries. 2012 Eur. J. Pharmacol. pmid:22154756
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Pucci M et al. Endocannabinoids stimulate human melanogenesis via type-1 cannabinoid receptor. 2012 J. Biol. Chem. pmid:22431736
McLaughlin RJ et al. Prefrontal cortical anandamide signaling coordinates coping responses to stress through a serotonergic pathway. 2012 Eur Neuropsychopharmacol pmid:22325231
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Alvheim AR et al. Dietary linoleic acid elevates endogenous 2-AG and anandamide and induces obesity. 2012 Obesity (Silver Spring) pmid:22334255
Engeli S et al. Circulating anandamide and blood pressure in patients with obstructive sleep apnea. 2012 J. Hypertens. pmid:23032139
Hauer D et al. Glucocorticoid-endocannabinoid interaction in cardiac surgical patients: relationship to early cognitive dysfunction and late depression. 2012 Rev Neurosci pmid:23006898
Scherma M et al. The anandamide transport inhibitor AM404 reduces the rewarding effects of nicotine and nicotine-induced dopamine elevations in the nucleus accumbens shell in rats. 2012 Br. J. Pharmacol. pmid:21557729
Osycka-Salut C et al. Anandamide induces sperm release from oviductal epithelia through nitric oxide pathway in bovines. 2012 PLoS ONE pmid:22363468
Vinod KY et al. Innate difference in the endocannabinoid signaling and its modulation by alcohol consumption in alcohol-preferring sP rats. 2012 Addict Biol pmid:21309960
Czikora Á et al. Vascular metabolism of anandamide to arachidonic acid affects myogenic constriction in response to intraluminal pressure elevation. 2012 Life Sci. pmid:22285599
Alger BE Endocannabinoids at the synapse a decade after the dies mirabilis (29 March 2001): what we still do not know. 2012 J. Physiol. (Lond.) pmid:22289914
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Lenglet S et al. Fatty acid amide hydrolase deficiency enhances intraplaque neutrophil recruitment in atherosclerotic mice. 2013 Arterioscler. Thromb. Vasc. Biol. pmid:23241405
Silva GB et al. Anandamide inhibits transport-related oxygen consumption in the loop of Henle by activating CB1 receptors. 2013 Am. J. Physiol. Renal Physiol. pmid:23220721
Citraro R et al. Antiepileptic action of N-palmitoylethanolamine through CB1 and PPAR-α receptor activation in a genetic model of absence epilepsy. 2013 Neuropharmacology pmid:23206503
Dékány A et al. The contractile effect of anandamide in the guinea-pig small intestine is mediated by prostanoids but not TRPV1 receptors or capsaicin-sensitive nerves. 2013 Basic Clin. Pharmacol. Toxicol. pmid:23216932
Romano MR and Lograno MD Signaling cross-talk between cannabinoid and muscarinic systems actives Rho-kinase and increases the contractile responses of the bovine ciliary muscle. 2013 Eur. J. Pharmacol. pmid:23396229
Romero TR et al. CB1 and CB2 cannabinoid receptor agonists induce peripheral antinociception by activation of the endogenous noradrenergic system. 2013 Anesth. Analg. pmid:23302980
Ho WS Modulation by 17β-estradiol of anandamide vasorelaxation in normotensive and hypertensive rats: a role for TRPV1 but not fatty acid amide hydrolase. 2013 Eur. J. Pharmacol. pmid:23340220
Zhuang J et al. The interaction of fatty acid amide hydrolase (FAAH) inhibitors with an anandamide carrier protein using (19)F-NMR. 2013 AAPS J pmid:23344792
Avraham Y et al. Novel acylethanolamide derivatives that modulate body weight through enhancement of hypothalamic pro-opiomelanocortin (POMC) and/or decreased neuropeptide Y (NPY). 2013 J. Med. Chem. pmid:23384387
Gebeh AK et al. Elevated anandamide and related N-acylethanolamine levels occur in the peripheral blood of women with ectopic pregnancy and are mirrored by changes in peripheral fatty acid amide hydrolase activity. 2013 J. Clin. Endocrinol. Metab. pmid:23372171
Li Q et al. Anandamide enhances expression of heat shock protein 72 to protect against ischemia-reperfusion injury in rat heart. 2013 J Physiol Sci pmid:23007622
Rivera P et al. Diet-dependent modulation of hippocampal expression of endocannabinoid signaling-related proteins in cannabinoid antagonist-treated obese rats. 2013 Eur. J. Neurosci. pmid:23033907
Starowicz K et al. Full inhibition of spinal FAAH leads to TRPV1-mediated analgesic effects in neuropathic rats and possible lipoxygenase-mediated remodeling of anandamide metabolism. 2013 PLoS ONE pmid:23573230
Subbanna S et al. Anandamide-CB1 receptor signaling contributes to postnatal ethanol-induced neonatal neurodegeneration, adult synaptic, and memory deficits. 2013 J. Neurosci. pmid:23575834
Descalzi F et al. Platelet-rich plasma exerts antinociceptive activity by a peripheral endocannabinoid-related mechanism. 2013 Tissue Eng Part A pmid:23578218
Morgan CJ et al. Cerebrospinal fluid anandamide levels, cannabis use and psychotic-like symptoms. 2013 Br J Psychiatry pmid:23580381
Blankman JL and Cravatt BF Chemical probes of endocannabinoid metabolism. 2013 Pharmacol. Rev. pmid:23512546
Akerman S et al. Endocannabinoids in the brainstem modulate dural trigeminovascular nociceptive traffic via CB1 and "triptan" receptors: implications in migraine. 2013 J. Neurosci. pmid:24027286
Adinolfi B et al. Anticancer activity of anandamide in human cutaneous melanoma cells. 2013 Eur. J. Pharmacol. pmid:24041928
Fonseca BM et al. The endocannabinoid anandamide induces apoptosis of rat decidual cells through a mechanism involving ceramide synthesis and p38 MAPK activation. 2013 Apoptosis pmid:24048885
Khlaifia A et al. Anandamide, cannabinoid type 1 receptor, and NMDA receptor activation mediate non-Hebbian presynaptically expressed long-term depression at the first central synapse for visceral afferent fibers. 2013 J. Neurosci. pmid:23904599
Citraro R et al. CB1 agonists, locally applied to the cortico-thalamic circuit of rats with genetic absence epilepsy, reduce epileptic manifestations. 2013 Epilepsy Res. pmid:23860329
Bernabò N et al. Systems biology analysis of the endocannabinoid system reveals a scale-free network with distinct roles for anandamide and 2-arachidonoylglycerol. 2013 OMICS pmid:24117401
Wenzel D et al. Endocannabinoid anandamide mediates hypoxic pulmonary vasoconstriction. 2013 Proc. Natl. Acad. Sci. U.S.A. pmid:24167249
Vavilin VA et al. Cytochrome P450 4F2 polymorphism in patients with liver cirrhosis. 2013 Bull. Exp. Biol. Med. pmid:24319743
Leung K et al. Role of FAAH-like anandamide transporter in anandamide inactivation. 2013 PLoS ONE pmid:24223930
Maione S et al. Piperazinyl carbamate fatty acid amide hydrolase inhibitors and transient receptor potential channel modulators as "dual-target" analgesics. 2013 Pharmacol. Res. pmid:23911581
Jourdan T et al. Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes. 2013 Nat. Med. pmid:23955712
O'Brien LD et al. Anandamide transport inhibition by ARN272 attenuates nausea-induced behaviour in rats, and vomiting in shrews (Suncus murinus). 2013 Br. J. Pharmacol. pmid:23991698