Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

Cross Reference

Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Neuralgia D009437 28 associated lipids
Fibromyalgia D005356 4 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Intestinal Pseudo-Obstruction D007418 5 associated lipids
Mycoses D009181 18 associated lipids
Bulimia D002032 3 associated lipids
Sleep Deprivation D012892 5 associated lipids
Urinary Incontinence D014549 4 associated lipids
Per page 10 20 50 100 | Total 105

PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

Download all related citations
Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Thomas EA et al. Fatty acid amide hydrolase, the degradative enzyme for anandamide and oleamide, has selective distribution in neurons within the rat central nervous system. 1997 J. Neurosci. Res. pmid:9452020
Bisogno T et al. The sleep inducing factor oleamide is produced by mouse neuroblastoma cells. 1997 Biochem. Biophys. Res. Commun. pmid:9344854
Mechoulam R et al. Anandamide may mediate sleep induction. 1997 Nature pmid:9288961
Hansen HS et al. Characterization of glutamate-induced formation of N-acylphosphatidylethanolamine and N-acylethanolamine in cultured neocortical neurons. 1997 J. Neurochem. pmid:9231736
Castellano C et al. The effects of anandamide on memory consolidation in mice involve both D1 and D2 dopamine receptors. 1997 Behav Pharmacol pmid:9832956
Zygmunt PM et al. Studies on the effects of anandamide in rat hepatic artery. 1997 Br. J. Pharmacol. pmid:9422814
Jarrahian A and Hillard CJ Arachidonylethanolamide (anandamide) binds with low affinity to dihydropyridine binding sites in brain membranes. 1997 Prostaglandins Leukot. Essent. Fatty Acids pmid:9431821
Sasaki T and Chang MC N-arachidonylethanolamine (anandamide) formation from N-arachidonylphosphatidylethanolamine in rat brain membranes. 1997 Life Sci. pmid:9365227
Randall MD and Kendall DA Involvement of a cannabinoid in endothelium-derived hyperpolarizing factor-mediated coronary vasorelaxation. 1997 Eur. J. Pharmacol. pmid:9369375
Burkey TH et al. Relative efficacies of cannabinoid CB1 receptor agonists in the mouse brain. 1997 Eur. J. Pharmacol. pmid:9384246
Calignano A et al. Potentiation of anandamide hypotension by the transport inhibitor, AM404. 1997 Eur. J. Pharmacol. pmid:9389389
Deutsch DG and Makriyannis A Inhibitors of anandamide breakdown. 1997 NIDA Res. Monogr. pmid:9260184
Seltzman HH et al. Synthesis and pharmacological comparison of dimethylheptyl and pentyl analogs of anandamide. 1997 J. Med. Chem. pmid:9357529
Willoughby KA et al. The biodisposition and metabolism of anandamide in mice. 1997 J. Pharmacol. Exp. Ther. pmid:9223560
Beltramo M et al. Inhibition of anandamide hydrolysis in rat brain tissue by (E)-6-(bromomethylene) tetrahydro-3-(1-naphthalenyl)-2H-pyran-2-one. 1997 FEBS Lett. pmid:9091314
Thumser AE et al. A fluorescence displacement assay for the measurement of arachidonoyl ethanolamide (anandamide) and oleoyl amide (octadecenoamide) hydrolysis. 1997 Biochem. Pharmacol. pmid:9065749
Ryan WJ et al. Potent anandamide analogs: the effect of changing the length and branching of the end pentyl chain. 1997 J. Med. Chem. pmid:9357528
Bisogno T et al. Biosynthesis, release and degradation of the novel endogenous cannabimimetic metabolite 2-arachidonoylglycerol in mouse neuroblastoma cells. 1997 Biochem. J. pmid:9065792
De Petrocellis L et al. Novel inhibitors of brain, neuronal, and basophilic anandamide amidohydrolase. 1997 Biochem. Biophys. Res. Commun. pmid:9070224
Deutsch DG et al. Fatty acid sulfonyl fluorides inhibit anandamide metabolism and bind to the cannabinoid receptor. 1997 Biochem. Biophys. Res. Commun. pmid:9070252
Lake KD et al. Cardiovascular effects of anandamide in anesthetized and conscious normotensive and hypertensive rats. 1997 Hypertension pmid:9149688
Bisogno T et al. Occurrence and metabolism of anandamide and related acyl-ethanolamides in ovaries of the sea urchin Paracentrotus lividus. 1997 Biochim. Biophys. Acta pmid:9150253
Stefano GB et al. Identification and characterization of the leech CNS cannabinoid receptor: coupling to nitric oxide release. 1997 Brain Res. pmid:9125406
Mechoulam R Todd's achievement. 1997 Nature pmid:9126725
Koga D et al. Liquid chromatographic-atmospheric pressure chemical ionization mass spectrometric determination of anandamide and its analogs in rat brain and peripheral tissues. 1997 J. Chromatogr. B Biomed. Sci. Appl. pmid:9106024
Schmid PC et al. Changes in anandamide levels in mouse uterus are associated with uterine receptivity for embryo implantation. 1997 Proc. Natl. Acad. Sci. U.S.A. pmid:9108127
Cadas H et al. Occurrence and biosynthesis of endogenous cannabinoid precursor, N-arachidonoyl phosphatidylethanolamine, in rat brain. 1997 J. Neurosci. pmid:9006968
Bisogno T et al. Biosynthesis, uptake, and degradation of anandamide and palmitoylethanolamide in leukocytes. 1997 J. Biol. Chem. pmid:9013571
Fowler CJ et al. Ibuprofen inhibits the metabolism of the endogenous cannabimimetic agent anandamide. 1997 Pharmacol. Toxicol. pmid:9060042
Pate DW et al. Effects of topical alpha-substituted anandamides on intraocular pressure in normotensive rabbits. 1997 Pharm. Res. pmid:9453062
Hillard CJ and Campbell WB Biochemistry and pharmacology of arachidonylethanolamide, a putative endogenous cannabinoid. 1997 J. Lipid Res. pmid:9458263
van der Stelt M et al. The effect of hydroxylation of linoleoyl amides on their cannabinomimetic properties. 1997 FEBS Lett. pmid:9357990
Beltramo M et al. Functional role of high-affinity anandamide transport, as revealed by selective inhibition. 1997 Science pmid:9262477
Valk P et al. Anandamide, a natural ligand for the peripheral cannabinoid receptor is a novel synergistic growth factor for hematopoietic cells. 1997 Blood pmid:9269762
Brodkin J and Moerschbaecher JM SR141716A antagonizes the disruptive effects of cannabinoid ligands on learning in rats. 1997 J. Pharmacol. Exp. Ther. pmid:9316868
Twitchell W et al. Cannabinoids inhibit N- and P/Q-type calcium channels in cultured rat hippocampal neurons. 1997 J. Neurophysiol. pmid:9242259
Matsuda S et al. Metabolism of anandamide, an endogenous cannabinoid receptor ligand, in porcine ocular tissues. 1997 Exp. Eye Res. pmid:9245900
Wagner JA et al. Activation of peripheral CB1 cannabinoid receptors in haemorrhagic shock. 1997 Nature pmid:9394002
Compton DR and Martin BR The effect of the enzyme inhibitor phenylmethylsulfonyl fluoride on the pharmacological effect of anandamide in the mouse model of cannabimimetic activity. 1997 J. Pharmacol. Exp. Ther. pmid:9399986
Stella N et al. A second endogenous cannabinoid that modulates long-term potentiation. 1997 Nature pmid:9285589
Mikawa Y et al. Ocular activity of topically administered anandamide in the rabbit. 1997 Jul-Aug Jpn. J. Ophthalmol. pmid:9304433
Barnett-Norris J et al. Exploration of biologically relevant conformations of anandamide, 2-arachidonylglycerol, and their analogues using conformational memories. 1998 J. Med. Chem. pmid:9822555
Maccarrone M et al. Anandamide hydrolysis by human cells in culture and brain. 1998 J. Biol. Chem. pmid:9822713
Axelrod J and Felder CC Cannabinoid receptors and their endogenous agonist, anandamide. 1998 Neurochem. Res. pmid:9566594
Randall MD and Kendall DA Endocannabinoids: a new class of vasoactive substances. 1998 Trends Pharmacol. Sci. pmid:9550942
Van der Kloot W et al. Calcitonin gene-related peptide acts presynaptically to increase quantal size and output at frog neuromuscular junctions. 1998 J. Physiol. (Lond.) pmid:9508830
Di Marzo V et al. The novel endogenous cannabinoid 2-arachidonoylglycerol is inactivated by neuronal- and basophil-like cells: connections with anandamide. 1998 Biochem. J. pmid:9512456
Adams IB et al. Assessment of anandamide interaction with the cannabinoid brain receptor: SR 141716A antagonism studies in mice and autoradiographic analysis of receptor binding in rat brain. 1998 J. Pharmacol. Exp. Ther. pmid:9495885
Pratt PF et al. N-arachidonylethanolamide relaxation of bovine coronary artery is not mediated by CB1 cannabinoid receptor. 1998 Am. J. Physiol. pmid:9458889
Paria BC et al. Effects of cannabinoids on preimplantation mouse embryo development and implantation are mediated by brain-type cannabinoid receptors. 1998 Biol. Reprod. pmid:9623610