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Long-term consequences of URB597 administration during adolescence on cannabinoid CB1 receptor binding in brain areas. |
2009 |
Brain Res. |
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Acute hypertension reveals depressor and vasodilator effects of cannabinoids in conscious rats. |
2009 |
Br. J. Pharmacol. |
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Doroshenko P and Renaud LP |
Acid-sensitive TASK-like K+ conductances contribute to resting membrane potential and to orexin-induced membrane depolarization in rat thalamic paraventricular nucleus neurons. |
2009 |
Neuroscience |
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Sleep deprivation increases oleoylethanolamide in human cerebrospinal fluid. |
2009 |
J Neural Transm |
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Endocannabinoid-dependent plasticity at GABAergic and glutamatergic synapses in the striatum is regulated by synaptic activity. |
2009 |
Eur. J. Neurosci. |
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Biology of endocannabinoid synthesis system. |
2009 |
Prostaglandins Other Lipid Mediat. |
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Low type I cannabinoid receptor levels characterize placental villous in labouring delivery. |
2009 |
Placenta |
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Wheal AJ and Randall MD |
Effects of hypertension on vasorelaxation to endocannabinoids in vitro. |
2009 |
Eur. J. Pharmacol. |
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Role of cannabinoid CB1 receptors on macronutrient selection and satiety in rats. |
2009 |
Physiol. Behav. |
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Cannabinoid type 1 receptors in human skeletal muscle cells participate in the negative crosstalk between fat and muscle. |
2009 |
Diabetologia |
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Biochemical and biological properties of 4-(3-phenyl-[1,2,4] thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide, a mechanism-based inhibitor of fatty acid amide hydrolase. |
2009 |
Anesth. Analg. |
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Vignali M et al. |
The endocannabinoid anandamide inhibits potassium conductance in rat cortical astrocytes. |
2009 |
Glia |
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Fernandez-Solari J et al. |
Anandamide injected into the lateral ventricle of the brain inhibits submandibular salivary secretion by attenuating parasympathetic neurotransmission. |
2009 |
Braz. J. Med. Biol. Res. |
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Dose-response effects of systemic anandamide administration in mice sequentially submitted to the open field and elevated plus-maze tests. |
2009 |
Braz. J. Med. Biol. Res. |
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Opioid receptor and NO/cGMP pathway as a mechanism of peripheral antinociceptive action of the cannabinoid receptor agonist anandamide. |
2009 |
Life Sci. |
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Endocannabinoids mediate anxiolytic-like effect of acetaminophen via CB1 receptors. |
2009 |
Prog. Neuropsychopharmacol. Biol. Psychiatry |
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Murakami T et al. |
Antimicrobial cathelicidin polypeptide CAP11 suppresses the production and release of septic mediators in D-galactosamine-sensitized endotoxin shock mice. |
2009 |
Int. Immunol. |
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Endogenous ethanolamide analysis in human plasma using HPLC tandem MS with electrospray ionization. |
2009 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
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Anandamide-induced cell death: dual effects in primary rat decidual cell cultures. |
2009 |
Placenta |
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Guasti L et al. |
Minocycline treatment inhibits microglial activation and alters spinal levels of endocannabinoids in a rat model of neuropathic pain. |
2009 |
Mol Pain |
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Bittner S et al. |
TASK1 modulates inflammation and neurodegeneration in autoimmune inflammation of the central nervous system. |
2009 |
Brain |
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A cytochrome P450-derived epoxygenated metabolite of anandamide is a potent cannabinoid receptor 2-selective agonist. |
2009 |
Mol. Pharmacol. |
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The endocannabinoid system and pivotal role of the CB2 receptor in mouse spermatogenesis. |
2009 |
Proc. Natl. Acad. Sci. U.S.A. |
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Modulation of motor and sensory pathways of the peristaltic reflex by cannabinoids. |
2009 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
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Endocannabinoids may mediate the ability of (n-3) fatty acids to reduce ectopic fat and inflammatory mediators in obese Zucker rats. |
2009 |
J. Nutr. |
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Anandamide increases swelling and reduces calcium sensitivity of mitochondria. |
2009 |
Biochem. Biophys. Res. Commun. |
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Endogenous cannabinoids induce fever through the activation of CB1 receptors. |
2009 |
Br. J. Pharmacol. |
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Dual modulation of CNS voltage-gated calcium channels by cannabinoids: Focus on CB1 receptor-independent effects. |
2009 |
Cell Calcium |
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Enzymatic formation of anandamide. |
2009 |
Vitam. Horm. |
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Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain. |
2009 |
Chem. Biol. |
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Inactivation and biotransformation of the endogenous cannabinoids anandamide and 2-arachidonoylglycerol. |
2009 |
Mol. Pharmacol. |
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Pharmacological synergism between cannabinoids and paclitaxel in gastric cancer cell lines. |
2009 |
J. Surg. Res. |
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Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress. |
2009 |
Psychoneuroendocrinology |
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Endogenous anandamide and cannabinoid receptor-2 contribute to electroacupuncture analgesia in rats. |
2009 |
J Pain |
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Inhibition of hepatic tumour necrosis factor-alpha attenuates the anandamide-induced vasoconstrictive response in cirrhotic rat livers. |
2009 |
Liver Int. |
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N-acylethanolamines, anandamide and food intake. |
2009 |
Biochem. Pharmacol. |
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Targeted stable-isotope dilution GC-MS/MS analysis of the endocannabinoid anandamide and other fatty acid ethanol amides in human plasma. |
2009 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
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The insertion and transport of anandamide in synthetic lipid membranes are both cholesterol-dependent. |
2009 |
PLoS ONE |
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Trezza V and Vanderschuren LJ |
Divergent effects of anandamide transporter inhibitors with different target selectivity on social play behavior in adolescent rats. |
2009 |
J. Pharmacol. Exp. Ther. |
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Cannabinoid regulation of nitric oxide synthase I (nNOS) in neuronal cells. |
2009 |
J Neuroimmune Pharmacol |
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The endocannabinoid anandamide inhibits kinin B1 receptor sensitization through cannabinoid CB1 receptor stimulation in human umbilical vein. |
2009 |
Eur. J. Pharmacol. |
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The endocannabinoid system in bull sperm and bovine oviductal epithelium: role of anandamide in sperm-oviduct interaction. |
2009 |
Reproduction |
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Mendiguren A and Pineda J |
Effect of the CB(1) receptor antagonists rimonabant and AM251 on the firing rate of dorsal raphe nucleus neurons in rat brain slices. |
2009 |
Br. J. Pharmacol. |
pmid:19845674
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Guindon J and Beaulieu P |
The role of the endogenous cannabinoid system in peripheral analgesia. |
2009 |
Curr Mol Pharmacol |
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Spatio-temporal expression patterns of anandamide-binding receptors in rat implantation sites: evidence for a role of the endocannabinoid system during the period of placental development. |
2009 |
Reprod. Biol. Endocrinol. |
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Postnatal maturation of the gastrointestinal tract: a functional and immunohistochemical study in the guinea-pig ileum at weaning. |
2009 |
Neurosci. Lett. |
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Discriminative stimulus functions in rats of AM1346, a high-affinity CB1R selective anandamide analog. |
2009 |
Psychopharmacology (Berl.) |
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Differential alteration of hippocampal excitatory synaptic transmission by cannabinoid ligands. |
2009 |
J. Neurosci. Res. |
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Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects. |
2009 |
Nat. Chem. Biol. |
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Opposite effects of anandamide and N-arachidonoyl dopamine in the regulation of prostaglandin E and 8-iso-PGF formation in primary glial cells. |
2009 |
J. Neurochem. |
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Endothelin-1 inhibits background two-pore domain channel TASK-1 in primary human pulmonary artery smooth muscle cells. |
2009 |
Am. J. Respir. Cell Mol. Biol. |
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17beta-oestradiol and progesterone regulate anandamide synthesis in the rat uterus. |
2009 |
Reprod. Biomed. Online |
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Functional characterization of nonadrenergic noncholinergic neurotransmitter release via endocannabinoids: an in vitro study in rabbit corpus cavernosum. |
2009 |
J Sex Med |
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The endocannabinoid system is modulated in response to spinal cord injury in rats. |
2009 |
Neurobiol. Dis. |
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TRPV1 channels facilitate glutamate transmission in the striatum. |
2009 |
Mol. Cell. Neurosci. |
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The neuroprotective impact of the leak potassium channel TASK1 on stroke development in mice. |
2009 |
Neurobiol. Dis. |
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Genetic loss of Faah compromises male fertility in mice. |
2009 |
Biol. Reprod. |
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A solid-phase method for the extraction and measurement of anandamide from multiple human biomatrices. |
2009 |
Anal. Biochem. |
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Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo. |
2009 |
Proc. Natl. Acad. Sci. U.S.A. |
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Reciprocal changes in vanilloid (TRPV1) and endocannabinoid (CB1) receptors contribute to visceral hyperalgesia in the water avoidance stressed rat. |
2009 |
Gut |
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A role for CB2 receptors in anandamide signalling pathways involved in the regulation of IL-12 and IL-23 in microglial cells. |
2009 |
Biochem. Pharmacol. |
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McMahon LR |
Apparent affinity estimates of rimonabant in combination with anandamide and chemical analogs of anandamide in rhesus monkeys discriminating Delta9-tetrahydrocannabinol. |
2009 |
Psychopharmacology (Berl.) |
pmid:18592221
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The endocannabinoid system as a target for the treatment of cannabis dependence. |
2009 |
Neuropharmacology |
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TRPV1-mediated itch in seasonal allergic rhinitis. |
2009 |
Allergy |
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Sleep-inducing factors. |
2009 |
CNS Neurol Disord Drug Targets |
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Characterization of the endocannabinoid system in human neuronal cells and proteomic analysis of anandamide-induced apoptosis. |
2009 |
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Circulating endocannabinoid concentrations during orthostatic stress. |
2009 |
Clin. Auton. Res. |
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Expression of the endocannabinoid system in the bi-potential HEL cell line: commitment to the megakaryoblastic lineage by 2-arachidonoylglycerol. |
2009 |
J. Mol. Med. |
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Hill MN et al. |
Suppression of amygdalar endocannabinoid signaling by stress contributes to activation of the hypothalamic-pituitary-adrenal axis. |
2009 |
Neuropsychopharmacology |
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The protective role of anandamide in mesenteric ischemia reperfusion injury in guinea pig. |
2009 |
Bratisl Lek Listy |
pmid:19711821
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Thors L and Fowler CJ |
Effect of nitric oxide donors on membrane tritium accumulation of endocannabinoids and related endogenous lipids. |
2009 |
Eur. J. Pharmacol. |
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Enhanced anandamide plasma levels in patients with complex regional pain syndrome following traumatic injury: a preliminary report. |
2009 |
Eur Surg Res |
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Cannabinoid in the nucleus accumbens enhances the intake of palatable solution. |
2009 |
Neuroreport |
pmid:19734811
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Campos AC and Guimarães FS |
Evidence for a potential role for TRPV1 receptors in the dorsolateral periaqueductal gray in the attenuation of the anxiolytic effects of cannabinoids. |
2009 |
Prog. Neuropsychopharmacol. Biol. Psychiatry |
pmid:19735690
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Synthesis, in vitro and in vivo evaluation, and radiolabeling of aryl anandamide analogues as candidate radioligands for in vivo imaging of fatty acid amide hydrolase in the brain. |
2009 |
J. Med. Chem. |
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Role of insulin as a negative regulator of plasma endocannabinoid levels in obese and nonobese subjects. |
2009 |
Eur. J. Endocrinol. |
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Synthesis and pharmacological evaluation of sulfamide-based analogues of anandamide. |
2009 |
Eur J Med Chem |
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Lack of effect of cannabis-based treatment on clinical and laboratory measures in multiple sclerosis. |
2009 |
Neurol. Sci. |
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Plasma endocannabinoid levels in multiple sclerosis. |
2009 |
J. Neurol. Sci. |
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The antinociceptive interaction of anandamide and adenosine at the spinal level. |
2009 |
Pharmacol. Biochem. Behav. |
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Radiosynthesis, in vitro and in vivo evaluation of 123I-labeled anandamide analogues for mapping brain FAAH. |
2009 |
Bioorg. Med. Chem. |
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CB1 cannabinoid receptor-dependent and -independent inhibition of depolarization-induced calcium influx in oligodendrocytes. |
2009 |
Glia |
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Anandamide preserves cardiac function and geometry in an acute doxorubicin cardiotoxicity rat model. |
2009 |
J. Cardiovasc. Pharmacol. Ther. |
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Sensitization of capsaicin-sensitive lung vagal afferents by anandamide in rats: role of transient receptor potential vanilloid 1 receptors. |
2009 |
J. Appl. Physiol. |
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Kurjak M et al. |
Differential stimulatory effects of cannabinoids on VIP release and NO synthase activity in synaptosomal fractions from rat ileum. |
2008 Oct-Dec |
Neuropeptides |
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The endocannabinoid anandamide neither impairs in vitro T-cell function nor induces regulatory T-cell generation. |
2008 Nov-Dec |
Anticancer Res. |
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Sakamoto Y et al. |
Effectiveness of continuous hemodiafiltration using a polymethylmethacrylate membrane hemofilter after polymyxin B-immobilized fiber column therapy of septic shock. |
2008 Jan-Feb |
ASAIO J. |
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Rossi C et al. |
Endocannabinoids in platelets of chronic migraine patients and medication-overuse headache patients: relation with serotonin levels. |
2008 |
Eur. J. Clin. Pharmacol. |
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Di Marzo V et al. |
The role of endocannabinoids in the regulation of gastric emptying: alterations in mice fed a high-fat diet. |
2008 |
Br. J. Pharmacol. |
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Simon GM and Cravatt BF |
Anandamide biosynthesis catalyzed by the phosphodiesterase GDE1 and detection of glycerophospho-N-acyl ethanolamine precursors in mouse brain. |
2008 |
J. Biol. Chem. |
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Plasma anandamide concentration and pregnancy outcome in women with threatened miscarriage. |
2008 |
JAMA |
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The role of endocannabinoids in the regulation of luteinizing hormone and prolactin release. Differences between the effects of AEA and 2AG. |
2008 |
Mol. Cell. Endocrinol. |
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Khasabova IA et al. |
A decrease in anandamide signaling contributes to the maintenance of cutaneous mechanical hyperalgesia in a model of bone cancer pain. |
2008 |
J. Neurosci. |
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Hill MN et al. |
Differential effects of the antidepressants tranylcypromine and fluoxetine on limbic cannabinoid receptor binding and endocannabinoid contents. |
2008 |
J Neural Transm |
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Antinociceptive effects of tetrazole inhibitors of endocannabinoid inactivation: cannabinoid and non-cannabinoid receptor-mediated mechanisms. |
2008 |
Br. J. Pharmacol. |
pmid:18660824
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Fowler CJ |
"The tools of the trade"--an overview of the pharmacology of the endocannabinoid system. |
2008 |
Curr. Pharm. Des. |
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McPartland JM et al. |
Cannabimimetic effects modulated by cholinergic compounds. |
2008 |
Addict Biol |
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Mechanisms for recycling and biosynthesis of endogenous cannabinoids anandamide and 2-arachidonylglycerol. |
2008 |
J. Neurochem. |
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TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons. |
2008 |
J. Neurosci. |
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Mass-spectrometric identification of anandamide and 2-arachidonoylglycerol in nematodes. |
2008 |
Chem. Biodivers. |
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