Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Headache Disorders, Secondary D051271 1 associated lipids
Somatosensory Disorders D020886 1 associated lipids
Orthostatic Intolerance D054971 1 associated lipids
Sleep Disorders, Intrinsic D020919 1 associated lipids
Vascular System Injuries D057772 2 associated lipids
Amnesia, Anterograde D020324 2 associated lipids
Substance-Related Disorders D019966 2 associated lipids
Ocular Hypotension D015814 2 associated lipids
Bulimia D002032 3 associated lipids
Acute Pain D059787 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Okine BN et al. Lack of effect of chronic pre-treatment with the FAAH inhibitor URB597 on inflammatory pain behaviour: evidence for plastic changes in the endocannabinoid system. 2012 Br. J. Pharmacol. pmid:22595021
Grainger J and Boachie-Ansah G Anandamide-induced relaxation of sheep coronary arteries: the role of the vascular endothelium, arachidonic acid metabolites and potassium channels. 2001 Br. J. Pharmacol. pmid:11682448
Sun Y et al. Cannabinoid activation of PPAR alpha; a novel neuroprotective mechanism. 2007 Br. J. Pharmacol. pmid:17906680
Ross RA et al. Structure-activity relationship for the endogenous cannabinoid, anandamide, and certain of its analogues at vanilloid receptors in transfected cells and vas deferens. 2001 Br. J. Pharmacol. pmid:11159715
White R and Hiley CR The actions of some cannabinoid receptor ligands in the rat isolated mesenteric artery. 1998 Br. J. Pharmacol. pmid:9806337
Köfalvi A et al. Anandamide and NADA bi-directionally modulate presynaptic Ca2+ levels and transmitter release in the hippocampus. 2007 Br. J. Pharmacol. pmid:17435795
Roberts LA et al. Anandamide is a partial agonist at native vanilloid receptors in acutely isolated mouse trigeminal sensory neurons. 2002 Br. J. Pharmacol. pmid:12359623
Izzo AA et al. Inhibitory effect of cannabichromene, a major non-psychotropic cannabinoid extracted from Cannabis sativa, on inflammation-induced hypermotility in mice. 2012 Br. J. Pharmacol. pmid:22300105
White R et al. Mechanisms of anandamide-induced vasorelaxation in rat isolated coronary arteries. 2001 Br. J. Pharmacol. pmid:11606334
Tucker RC et al. The endogenous cannabinoid agonist, anandamide stimulates sensory nerves in guinea-pig airways. 2001 Br. J. Pharmacol. pmid:11226144
Woodhams SG et al. Spinal administration of the monoacylglycerol lipase inhibitor JZL184 produces robust inhibitory effects on nociceptive processing and the development of central sensitization in the rat. 2012 Br. J. Pharmacol. pmid:22924700
Ghasemi M et al. Role of the nitric oxide pathway and the endocannabinoid system in neurogenic relaxation of corpus cavernosum from biliary cirrhotic rats. 2007 Br. J. Pharmacol. pmid:17486141
Ameri A et al. Effects of the endogeneous cannabinoid, anandamide, on neuronal activity in rat hippocampal slices. 1999 Br. J. Pharmacol. pmid:10372827
Fraga D et al. Endogenous cannabinoids induce fever through the activation of CB1 receptors. 2009 Br. J. Pharmacol. pmid:19681872
Lau BK et al. Endocannabinoid modulation by FAAH and monoacylglycerol lipase within the analgesic circuitry of the periaqueductal grey. 2014 Br. J. Pharmacol. pmid:25041240
Hillard CJ and Jarrahian A Cellular accumulation of anandamide: consensus and controversy. 2003 Br. J. Pharmacol. pmid:12970089
O'Sullivan SE et al. Heterogeneity in the mechanisms of vasorelaxation to anandamide in resistance and conduit rat mesenteric arteries. 2004 Br. J. Pharmacol. pmid:15148250
Randall MD et al. The complexities of the cardiovascular actions of cannabinoids. 2004 Br. J. Pharmacol. pmid:15131000
Di Marzo V et al. The role of endocannabinoids in the regulation of gastric emptying: alterations in mice fed a high-fat diet. 2008 Br. J. Pharmacol. pmid:18223666
Vandevoorde S et al. Lack of selectivity of URB602 for 2-oleoylglycerol compared to anandamide hydrolysis in vitro. 2007 Br. J. Pharmacol. pmid:17143303
De Petrocellis L et al. A re-evaluation of 9-HODE activity at TRPV1 channels in comparison with anandamide: enantioselectivity and effects at other TRP channels and in sensory neurons. 2012 Br. J. Pharmacol. pmid:22861649
Wheal AJ et al. Effects of chronic nitric oxide synthase inhibition on the cardiovascular responses to cannabinoids in vivo and in vitro. 2007 Br. J. Pharmacol. pmid:17245361
Izzo AA et al. Effect of vanilloid drugs on gastrointestinal transit in mice. 2001 Br. J. Pharmacol. pmid:11264233
Gauldie SD et al. Anandamide activates peripheral nociceptors in normal and arthritic rat knee joints. 2001 Br. J. Pharmacol. pmid:11159713
Stewart JL and McMahon LR The fatty acid amide hydrolase inhibitor URB 597: interactions with anandamide in rhesus monkeys. 2011 Br. J. Pharmacol. pmid:21449917
Patel S et al. The general anesthetic propofol increases brain N-arachidonylethanolamine (anandamide) content and inhibits fatty acid amide hydrolase. 2003 Br. J. Pharmacol. pmid:12839875
Gamaleddin I et al. The selective anandamide transport inhibitor VDM11 attenuates reinstatement of nicotine seeking behaviour, but does not affect nicotine intake. 2011 Br. J. Pharmacol. pmid:21501143
Howlett AC et al. Endocannabinoid tone versus constitutive activity of cannabinoid receptors. 2011 Br. J. Pharmacol. pmid:21545414
Booker L et al. The fatty acid amide hydrolase (FAAH) inhibitor PF-3845 acts in the nervous system to reverse LPS-induced tactile allodynia in mice. 2012 Br. J. Pharmacol. pmid:21506952
Jamshidi N and Taylor DA Anandamide administration into the ventromedial hypothalamus stimulates appetite in rats. 2001 Br. J. Pharmacol. pmid:11704633
Costa B et al. AM404, an inhibitor of anandamide uptake, prevents pain behaviour and modulates cytokine and apoptotic pathways in a rat model of neuropathic pain. 2006 Br. J. Pharmacol. pmid:16770320
Solinas M et al. The endocannabinoid system in brain reward processes. 2008 Br. J. Pharmacol. pmid:18414385
Shouman B et al. Endocannabinoids potently protect the newborn brain against AMPA-kainate receptor-mediated excitotoxic damage. 2006 Br. J. Pharmacol. pmid:16682966
McHugh D et al. Δ(9) -Tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells. 2012 Br. J. Pharmacol. pmid:21595653
O'Sullivan SE et al. The effects of Delta9-tetrahydrocannabinol in rat mesenteric vasculature, and its interactions with the endocannabinoid anandamide. 2005 Br. J. Pharmacol. pmid:15821751
Guindon J et al. Peripheral antinociceptive effects of inhibitors of monoacylglycerol lipase in a rat model of inflammatory pain. 2011 Br. J. Pharmacol. pmid:21198549
Craib SJ et al. A possible role of lipoxygenase in the activation of vanilloid receptors by anandamide in the guinea-pig bronchus. 2001 Br. J. Pharmacol. pmid:11522594
White R and Hiley CR A comparison of EDHF-mediated and anandamide-induced relaxations in the rat isolated mesenteric artery. 1997 Br. J. Pharmacol. pmid:9422801
Zygmunt PM et al. Studies on the effects of anandamide in rat hepatic artery. 1997 Br. J. Pharmacol. pmid:9422814
Andrag E and Curtis MJ Feasibility of targeting ischaemia-related ventricular arrhythmias by mimicry of endogenous protection by endocannabinoids. 2013 Br. J. Pharmacol. pmid:23713981
Ford WR et al. Evidence of a novel site mediating anandamide-induced negative inotropic and coronary vasodilatator responses in rat isolated hearts. 2002 Br. J. Pharmacol. pmid:11877326
Scherma M et al. The anandamide transport inhibitor AM404 reduces the rewarding effects of nicotine and nicotine-induced dopamine elevations in the nucleus accumbens shell in rats. 2012 Br. J. Pharmacol. pmid:21557729
Mair KM et al. Interaction between anandamide and sphingosine-1-phosphate in mediating vasorelaxation in rat coronary artery. 2010 Br. J. Pharmacol. pmid:20718749
Jacobsson SO and Fowler CJ Characterization of palmitoylethanolamide transport in mouse Neuro-2a neuroblastoma and rat RBL-2H3 basophilic leukaemia cells: comparison with anandamide. 2001 Br. J. Pharmacol. pmid:11309246
Spicuzza L et al. Characterization of the effects of cannabinoids on guinea-pig tracheal smooth muscle tone: role in the modulation of acetylcholine release from parasympathetic nerves. 2000 Br. J. Pharmacol. pmid:10928980
Maione S et al. Antinociceptive effects of tetrazole inhibitors of endocannabinoid inactivation: cannabinoid and non-cannabinoid receptor-mediated mechanisms. 2008 Br. J. Pharmacol. pmid:18660824
Soria-Gómez E et al. Pharmacological enhancement of the endocannabinoid system in the nucleus accumbens shell stimulates food intake and increases c-Fos expression in the hypothalamus. 2007 Br. J. Pharmacol. pmid:17549045
Gardiner SM et al. Complex regional haemodynamic effects of anandamide in conscious rats. 2002 Br. J. Pharmacol. pmid:11959791
Jia Y et al. Anandamide induces cough in conscious guinea-pigs through VR1 receptors. 2002 Br. J. Pharmacol. pmid:12411414
Geraghty DP and Mazzone SB Respiratory actions of vanilloid receptor agonists in the nucleus of the solitary tract: comparison of resiniferatoxin with non-pungent agents and anandamide. 2002 Br. J. Pharmacol. pmid:12411424