Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Somatosensory Disorders D020886 1 associated lipids
Orthostatic Intolerance D054971 1 associated lipids
Sleep Disorders, Intrinsic D020919 1 associated lipids
Headache Disorders, Secondary D051271 1 associated lipids
Vascular System Injuries D057772 2 associated lipids
Amnesia, Anterograde D020324 2 associated lipids
Substance-Related Disorders D019966 2 associated lipids
Ocular Hypotension D015814 2 associated lipids
Cardiovirus Infections D018188 3 associated lipids
Schistosomiasis japonica D012554 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Authors Title Published Journal PubMed Link
Zygmunt PM et al. Anandamide - the other side of the coin. 2000 Trends Pharmacol. Sci. pmid:10664604
Jarrahian A et al. Structure-activity relationships among N-arachidonylethanolamine (Anandamide) head group analogues for the anandamide transporter. 2000 J. Neurochem. pmid:10820223
Davis JB et al. Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia. 2000 Nature pmid:10821274
Zygmunt PM et al. The anandamide transport inhibitor AM404 activates vanilloid receptors. 2000 Eur. J. Pharmacol. pmid:10822052
Maccarrone M et al. Anandamide and 2-arachidonoylglycerol inhibit fatty acid amide hydrolase by activating the lipoxygenase pathway of the arachidonate cascade. 2000 Biochem. Biophys. Res. Commun. pmid:11095952
Calignano A et al. A role for the endogenous cannabinoid system in the peripheral control of pain initiation. 2000 Prog. Brain Res. pmid:11098711
Valk P et al. Enhancement of erythropoietin-stimulated cell proliferation by Anandamide correlates with increased activation of the mitogen-activated protein kinases ERK1 and ERK2. 2000 Hematol. J. pmid:11920199
Di Marzo V et al. Levels, metabolism, and pharmacological activity of anandamide in CB(1) cannabinoid receptor knockout mice: evidence for non-CB(1), non-CB(2) receptor-mediated actions of anandamide in mouse brain. 2000 J. Neurochem. pmid:11080195
Rubino T et al. Loss of cannabinoid-stimulated guanosine 5'-O-(3-[(35)S]Thiotriphosphate) binding without receptor down-regulation in brain regions of anandamide-tolerant rats. 2000 J. Neurochem. pmid:11080200
Giuffrida A et al. Elevated circulating levels of anandamide after administration of the transport inhibitor, AM404. 2000 Eur. J. Pharmacol. pmid:11080522
Song ZH and Zhong M CB1 cannabinoid receptor-mediated cell migration. 2000 J. Pharmacol. Exp. Ther. pmid:10871313
Tytgat J et al. Cannabinoid mimics in chocolate utilized as an argument in court. 2000 Int. J. Legal Med. pmid:10876983
Andersson M et al. Neurotoxicity of glutamate in chick telencephalon neurons: reduction of toxicity by preincubation with carbachol, but not by the endogenous fatty acid amides anandamide and palmitoylethanolamide. 2000 Arch. Toxicol. pmid:10877002
Maccarrone M et al. Relation between decreased anandamide hydrolase concentrations in human lymphocytes and miscarriage. 2000 Lancet pmid:10776746
Houser SJ et al. Dynorphin B and spinal analgesia: induction of antinociception by the cannabinoids CP55,940, Delta(9)-THC and anandamide. 2000 Brain Res. pmid:10700588
Lay L et al. Pharmacological characterisation of cannabinoid CB(1) receptors in the rat and mouse. 2000 Eur. J. Pharmacol. pmid:10720647
Tiger G et al. Pharmacological properties of rat brain fatty acid amidohydrolase in different subcellular fractions using palmitoylethanolamide as substrate. 2000 Biochem. Pharmacol. pmid:10677581
Premkumar LS and Ahern GP Induction of vanilloid receptor channel activity by protein kinase C. 2000 Dec 21-28 Nature pmid:11140687
Hungund BL and Basavarajappa BS Are anandamide and cannabinoid receptors involved in ethanol tolerance? A review of the evidence. 2000 Mar-Apr Alcohol Alcohol. pmid:10787386
Ross RA et al. Structure-activity relationship for the endogenous cannabinoid, anandamide, and certain of its analogues at vanilloid receptors in transfected cells and vas deferens. 2001 Br. J. Pharmacol. pmid:11159715
Vanheel B and Van de Voorde J Regional differences in anandamide- and methanandamide-induced membrane potential changes in rat mesenteric arteries. 2001 J. Pharmacol. Exp. Ther. pmid:11160613
Ralevic V et al. Cannabinoid activation of recombinant and endogenous vanilloid receptors. 2001 Eur. J. Pharmacol. pmid:11672565
Christopoulos A and Wilson K Interaction of anandamide with the M(1) and M(4) muscarinic acetylcholine receptors. 2001 Brain Res. pmid:11578621
Fowler CJ et al. Fatty acid amide hydrolase: biochemistry, pharmacology, and therapeutic possibilities for an enzyme hydrolyzing anandamide, 2-arachidonoylglycerol, palmitoylethanolamide, and oleamide. 2001 Biochem. Pharmacol. pmid:11585048
Wagner JA et al. Hemodynamic effects of cannabinoids: coronary and cerebral vasodilation mediated by cannabinoid CB(1) receptors. 2001 Eur. J. Pharmacol. pmid:11448486
Boger DL et al. alpha-Keto heterocycle inhibitors of fatty acid amide hydrolase: carbonyl group modification and alpha-substitution. 2001 Bioorg. Med. Chem. Lett. pmid:11412972
Mendizábal VE et al. Long-term inhibition of nitric oxide synthase potentiates effects of anandamide in the rat mesenteric bed. 2001 Eur. J. Pharmacol. pmid:11567656
Rodríguez de Fonseca F et al. An anorexic lipid mediator regulated by feeding. 2001 Nature pmid:11700558
Jamshidi N and Taylor DA Anandamide administration into the ventromedial hypothalamus stimulates appetite in rats. 2001 Br. J. Pharmacol. pmid:11704633
Gurwitz D and Weizman A Fatty acid amide hydrolase inhibitors and the marijuana debate. 2001 Lancet pmid:11705595
Rice AS Cannabinoids and pain. 2001 Curr Opin Investig Drugs pmid:11575713
Karava V et al. Anandamide amidohydrolase activity, released in the medium by Tetrahymena pyriformis. Identification and partial characterization. 2001 FEBS Lett. pmid:11728445
Stamer WD et al. Cannabinoid CB(1) receptor expression, activation and detection of endogenous ligand in trabecular meshwork and ciliary process tissues. 2001 Eur. J. Pharmacol. pmid:11730719
Hayase T et al. Protective effects of cannabinoid receptor agonists against cocaine and other convulsant-induced toxic behavioural symptoms. 2001 J. Pharm. Pharmacol. pmid:11732755
Hansen HH et al. Anandamide, but not 2-arachidonoylglycerol, accumulates during in vivo neurodegeneration. 2001 J. Neurochem. pmid:11579150
Smith PJ and McQueen DS Anandamide induces cardiovascular and respiratory reflexes via vasosensory nerves in the anaesthetized rat. 2001 Br. J. Pharmacol. pmid:11588121
Izzo AA et al. The gastrointestinal pharmacology of cannabinoids. 2001 Curr Opin Pharmacol pmid:11757815
Wagner JA et al. Endogenous cannabinoids mediate hypotension after experimental myocardial infarction. 2001 J. Am. Coll. Cardiol. pmid:11738314
López-Rodríguez ML et al. Design, synthesis and biological evaluation of novel arachidonic acid derivatives as highly potent and selective endocannabinoid transporter inhibitors. 2001 J. Med. Chem. pmid:11741470
Chemin J et al. Direct inhibition of T-type calcium channels by the endogenous cannabinoid anandamide. 2001 EMBO J. pmid:11742980
Möhle R et al. Transendothelial migration of hematopoietic progenitor cells. Role of chemotactic factors. 2001 Ann. N. Y. Acad. Sci. pmid:11458515
Fride E et al. Critical role of the endogenous cannabinoid system in mouse pup suckling and growth. 2001 Eur. J. Pharmacol. pmid:11426843
Ugdyzhekova DS et al. Endogenous cannabinoid anandamide increases heart resistance to arrhythmogenic effects of epinephrine: role of CB(1) and CB(2) receptors. 2001 Bull. Exp. Biol. Med. pmid:11427912
Murillo-Rodríguez E et al. Anandamide-induced sleep is blocked by SR141716A, a CB1 receptor antagonist and by U73122, a phospholipase C inhibitor. 2001 Neuroreport pmid:11447321
Sprague J et al. Temperature-dependent activation of recombinant rat vanilloid VR1 receptors expressed in HEK293 cells by capsaicin and anandamide. 2001 Eur. J. Pharmacol. pmid:11448475
Porter AC and Felder CC The endocannabinoid nervous system: unique opportunities for therapeutic intervention. 2001 Pharmacol. Ther. pmid:11448725
Laine K et al. Effects of topical anandamide-transport inhibitors, AM404 and olvanil, on intraocular pressure in normotensive rabbits. 2001 Pharm. Res. pmid:11451037
Holt S et al. Effects of pH on the inhibition of fatty acid amidohydrolase by ibuprofen. 2001 Br. J. Pharmacol. pmid:11399668
Di Marzo V et al. Hypolocomotor effects in rats of capsaicin and two long chain capsaicin homologues. 2001 Eur. J. Pharmacol. pmid:11408034
Berdyshev EV et al. Activation of PAF receptors results in enhanced synthesis of 2-arachidonoylglycerol (2-AG) in immune cells. 2001 FASEB J. pmid:11641243