Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Somatosensory Disorders D020886 1 associated lipids
Orthostatic Intolerance D054971 1 associated lipids
Sleep Disorders, Intrinsic D020919 1 associated lipids
Headache Disorders, Secondary D051271 1 associated lipids
Vascular System Injuries D057772 2 associated lipids
Amnesia, Anterograde D020324 2 associated lipids
Ocular Hypotension D015814 2 associated lipids
Substance-Related Disorders D019966 2 associated lipids
Cardiovirus Infections D018188 3 associated lipids
Schistosomiasis japonica D012554 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Authors Title Published Journal PubMed Link
Grainger J and Boachie-Ansah G Anandamide-induced relaxation of sheep coronary arteries: the role of the vascular endothelium, arachidonic acid metabolites and potassium channels. 2001 Br. J. Pharmacol. pmid:11682448
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Christopoulos A and Wilson K Interaction of anandamide with the M(1) and M(4) muscarinic acetylcholine receptors. 2001 Brain Res. pmid:11578621
White R et al. Mechanisms of anandamide-induced vasorelaxation in rat isolated coronary arteries. 2001 Br. J. Pharmacol. pmid:11606334
Fowler CJ et al. Fatty acid amide hydrolase: biochemistry, pharmacology, and therapeutic possibilities for an enzyme hydrolyzing anandamide, 2-arachidonoylglycerol, palmitoylethanolamide, and oleamide. 2001 Biochem. Pharmacol. pmid:11585048
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Jamshidi N and Taylor DA Anandamide administration into the ventromedial hypothalamus stimulates appetite in rats. 2001 Br. J. Pharmacol. pmid:11704633
Gurwitz D and Weizman A Fatty acid amide hydrolase inhibitors and the marijuana debate. 2001 Lancet pmid:11705595
Rice AS Cannabinoids and pain. 2001 Curr Opin Investig Drugs pmid:11575713
Karava V et al. Anandamide amidohydrolase activity, released in the medium by Tetrahymena pyriformis. Identification and partial characterization. 2001 FEBS Lett. pmid:11728445
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Hansen HH et al. Anandamide, but not 2-arachidonoylglycerol, accumulates during in vivo neurodegeneration. 2001 J. Neurochem. pmid:11579150
Smith PJ and McQueen DS Anandamide induces cardiovascular and respiratory reflexes via vasosensory nerves in the anaesthetized rat. 2001 Br. J. Pharmacol. pmid:11588121
Maccarrone M et al. Lipopolysaccharide downregulates fatty acid amide hydrolase expression and increases anandamide levels in human peripheral lymphocytes. 2001 Arch. Biochem. Biophys. pmid:11556820
Crozier Willi G et al. Lipids in neural function: modulation of behavior by oral administration of endocannabinoids found in foods. 2001 Nestle Nutr Workshop Ser Clin Perform Programme pmid:11510437
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Vellani V et al. Protein kinase C activation potentiates gating of the vanilloid receptor VR1 by capsaicin, protons, heat and anandamide. 2001 J. Physiol. (Lond.) pmid:11483711
Maccarrone M et al. Anandamide degradation and N-acylethanolamines level in wild-type and CB1 cannabinoid receptor knockout mice of different ages. 2001 J. Neurochem. pmid:11461969
Ueda N et al. Purification and characterization of an acid amidase selective for N-palmitoylethanolamine, a putative endogenous anti-inflammatory substance. 2001 J. Biol. Chem. pmid:11463796
Deutsch DG et al. The cellular uptake of anandamide is coupled to its breakdown by fatty-acid amide hydrolase. 2001 J. Biol. Chem. pmid:11118429
Al-Hayani A et al. The endogenous cannabinoid anandamide activates vanilloid receptors in the rat hippocampal slice. 2001 Neuropharmacology pmid:11747904
Izzo AA et al. The gastrointestinal pharmacology of cannabinoids. 2001 Curr Opin Pharmacol pmid:11757815
Wagner JA et al. Endogenous cannabinoids mediate hypotension after experimental myocardial infarction. 2001 J. Am. Coll. Cardiol. pmid:11738314
López-Rodríguez ML et al. Design, synthesis and biological evaluation of novel arachidonic acid derivatives as highly potent and selective endocannabinoid transporter inhibitors. 2001 J. Med. Chem. pmid:11741470
Chemin J et al. Direct inhibition of T-type calcium channels by the endogenous cannabinoid anandamide. 2001 EMBO J. pmid:11742980
Bifulco M et al. Control by the endogenous cannabinoid system of ras oncogene-dependent tumor growth. 2001 FASEB J. pmid:11687506
De Petrocellis L et al. Palmitoylethanolamide enhances anandamide stimulation of human vanilloid VR1 receptors. 2001 FEBS Lett. pmid:11602256
Bisogno T et al. Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide. 2001 Br. J. Pharmacol. pmid:11606325
Möhle R et al. Transendothelial migration of hematopoietic progenitor cells. Role of chemotactic factors. 2001 Ann. N. Y. Acad. Sci. pmid:11458515
Olah Z et al. Anandamide activates vanilloid receptor 1 (VR1) at acidic pH in dorsal root ganglia neurons and cells ectopically expressing VR1. 2001 J. Biol. Chem. pmid:11333266
Calignano A et al. Antinociceptive activity of the endogenous fatty acid amide, palmitylethanolamide. 2001 Eur. J. Pharmacol. pmid:11426841
Fride E et al. Critical role of the endogenous cannabinoid system in mouse pup suckling and growth. 2001 Eur. J. Pharmacol. pmid:11426843
Ugdyzhekova DS et al. Endogenous cannabinoid anandamide increases heart resistance to arrhythmogenic effects of epinephrine: role of CB(1) and CB(2) receptors. 2001 Bull. Exp. Biol. Med. pmid:11427912
Di Marzo V et al. Hypolocomotor effects in rats of capsaicin and two long chain capsaicin homologues. 2001 Eur. J. Pharmacol. pmid:11408034
Breivogel CS et al. Evidence for a new G protein-coupled cannabinoid receptor in mouse brain. 2001 Mol. Pharmacol. pmid:11408610
Wang Y et al. Simultaneous measurement of anandamide and 2-arachidonoylglycerol by polymyxin B-selective adsorption and subsequent high-performance liquid chromatography analysis: increase in endogenous cannabinoids in the sera of patients with endotoxic shock. 2001 Anal. Biochem. pmid:11412008
De Petrocellis L et al. The vanilloid receptor (VR1)-mediated effects of anandamide are potently enhanced by the cAMP-dependent protein kinase. 2001 J. Neurochem. pmid:11413249
Morisset V and Urban L Cannabinoid-induced presynaptic inhibition of glutamatergic EPSCs in substantia gelatinosa neurons of the rat spinal cord. 2001 J. Neurophysiol. pmid:11431486
Bátkai S et al. Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis. 2001 Nat. Med. pmid:11433348
Maccarrone M et al. Progesterone up-regulates anandamide hydrolase in human lymphocytes: role of cytokines and implications for fertility. 2001 J. Immunol. pmid:11390466
Wenger T et al. The central cannabinoid receptor inactivation suppresses endocrine reproductive functions. 2001 Biochem. Biophys. Res. Commun. pmid:11394887
Maccarrone M et al. Gas chromatography-mass spectrometry analysis of endogenous cannabinoids in healthy and tumoral human brain and human cells in culture. 2001 J. Neurochem. pmid:11208922