Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Somatosensory Disorders D020886 1 associated lipids
Orthostatic Intolerance D054971 1 associated lipids
Sleep Disorders, Intrinsic D020919 1 associated lipids
Headache Disorders, Secondary D051271 1 associated lipids
Vascular System Injuries D057772 2 associated lipids
Amnesia, Anterograde D020324 2 associated lipids
Substance-Related Disorders D019966 2 associated lipids
Ocular Hypotension D015814 2 associated lipids
Cardiovirus Infections D018188 3 associated lipids
Schistosomiasis japonica D012554 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Authors Title Published Journal PubMed Link
Hutchins-Wiese HL et al. Hind limb suspension and long-chain omega-3 PUFA increase mRNA endocannabinoid system levels in skeletal muscle. 2012 J. Nutr. Biochem. pmid:22051448
Forsell PK et al. Metabolism of anandamide into eoxamides by 15-lipoxygenase-1 and glutathione transferases. 2012 Lipids pmid:22684912
Rogers TJ The molecular basis for neuroimmune receptor signaling. 2012 J Neuroimmune Pharmacol pmid:22935971
Chon SH et al. Over-expression of monoacylglycerol lipase (MGL) in small intestine alters endocannabinoid levels and whole body energy balance, resulting in obesity. 2012 PLoS ONE pmid:22937137
Brown WH et al. Fatty acid amide hydrolase ablation promotes ectopic lipid storage and insulin resistance due to centrally mediated hypothyroidism. 2012 Proc. Natl. Acad. Sci. U.S.A. pmid:22912404
Schreiber AK et al. Peripheral antinociceptive effect of anandamide and drugs that affect the endocannabinoid system on the formalin test in normal and streptozotocin-diabetic rats. 2012 Neuropharmacology pmid:22959964
Thomas KC et al. Contributions of TRPV1, endovanilloids, and endoplasmic reticulum stress in lung cell death in vitro and lung injury. 2012 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:21949157
Xiong W et al. A common molecular basis for exogenous and endogenous cannabinoid potentiation of glycine receptors. 2012 J. Neurosci. pmid:22496565
Kenessey I et al. Revisiting CB1 receptor as drug target in human melanoma. 2012 Pathol. Oncol. Res. pmid:22447182
Petrovszki Z et al. The effects of peptide and lipid endocannabinoids on arthritic pain at the spinal level. 2012 Anesth. Analg. pmid:22451592
Tamaki C et al. Anandamide induces endothelium-dependent vasoconstriction and CGRPergic nerve-mediated vasodilatation in the rat mesenteric vascular bed. 2012 J. Pharmacol. Sci. pmid:22510966
Czifra G et al. Endocannabinoids regulate growth and survival of human eccrine sweat gland-derived epithelial cells. 2012 J. Invest. Dermatol. pmid:22513781
Miller LL et al. Effects of alterations in cannabinoid signaling, alone and in combination with morphine, on pain-elicited and pain-suppressed behavior in mice. 2012 J. Pharmacol. Exp. Ther. pmid:22514333
De Petrocellis L et al. A re-evaluation of 9-HODE activity at TRPV1 channels in comparison with anandamide: enantioselectivity and effects at other TRP channels and in sensory neurons. 2012 Br. J. Pharmacol. pmid:22861649
Proto MC et al. Interaction of endocannabinoid system and steroid hormones in the control of colon cancer cell growth. 2012 J. Cell. Physiol. pmid:21412772
Campos AC et al. Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders. 2012 Philos. Trans. R. Soc. Lond., B, Biol. Sci. pmid:23108553
Psychoyos D et al. Cannabinoid receptor 1 signaling in embryo neurodevelopment. 2012 Birth Defects Res. B Dev. Reprod. Toxicol. pmid:22311661
Sordelli MS et al. Cyclooxygenase-2 prostaglandins mediate anandamide-inhibitory action on nitric oxide synthase activity in the receptive rat uterus. 2012 Eur. J. Pharmacol. pmid:22554772
Roy A et al. Anandamide modulates carotid sinus nerve afferent activity via TRPV1 receptors increasing responses to heat. 2012 J. Appl. Physiol. pmid:21903882
Butler RK et al. Fear-induced suppression of nociceptive behaviour and activation of Akt signalling in the rat periaqueductal grey: role of fatty acid amide hydrolase. 2012 J. Psychopharmacol. (Oxford) pmid:21926424
Khasabova IA et al. Cannabinoid type-1 receptor reduces pain and neurotoxicity produced by chemotherapy. 2012 J. Neurosci. pmid:22593077
Edwards JG et al. A novel non-CB1/TRPV1 endocannabinoid-mediated mechanism depresses excitatory synapses on hippocampal CA1 interneurons. 2012 Hippocampus pmid:21069781
Haruta C [Effects of anandamide on IL-11 production through the TRPV1 of human periodontal ligament cells]. 2012 Kokubyo Gakkai Zasshi pmid:22568077
Katona I and Freund TF Multiple functions of endocannabinoid signaling in the brain. 2012 Annu. Rev. Neurosci. pmid:22524785
Tong S et al. Diagnostic accuracy of maternal serum macrophage inhibitory cytokine-1 and pregnancy-associated plasma protein-A at 6-10 weeks of gestation to predict miscarriage. 2012 Obstet Gynecol pmid:22525911
Goonawardena AV et al. Pharmacological elevation of anandamide impairs short-term memory by altering the neurophysiology in the hippocampus. 2011 Oct-Nov Neuropharmacology pmid:21767554
Frazier CJ Key questions of endocannabinoid signalling in the CNS: which, where and when? 2011 J. Physiol. (Lond.) pmid:22001725
Ito T et al. Propofol protects against anandamide-induced injury in human umbilical vein endothelial cells. 2011 Kurume Med J pmid:22027193
Alenmyr L et al. TRPV1 and TRPA1 stimulation induces MUC5B secretion in the human nasal airway in vivo. 2011 Clin Physiol Funct Imaging pmid:21981454
Hayase T Differential effects of TRPV1 receptor ligands against nicotine-induced depression-like behaviors. 2011 BMC Pharmacol. pmid:21767384
Romero TR et al. The neuronal NO synthase participation in the peripheral antinociception mechanism induced by several analgesic drugs. 2011 Nitric Oxide pmid:21875681
Dean C Cannabinoid and GABA modulation of sympathetic nerve activity and blood pressure in the dorsal periaqueductal gray of the rat. 2011 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:21940402
Sridar C et al. Anandamide oxidation by wild-type and polymorphically expressed CYP2B6 and CYP2D6. 2011 Drug Metab. Dispos. pmid:21289075
Kim HY et al. A synaptogenic amide N-docosahexaenoylethanolamide promotes hippocampal development. 2011 Prostaglandins Other Lipid Mediat. pmid:21810478
Brighton PJ et al. Characterization of the endocannabinoid system, CB(1) receptor signalling and desensitization in human myometrium. 2011 Br. J. Pharmacol. pmid:21486283
Walentiny DM et al. The endogenous cannabinoid anandamide shares discriminative stimulus effects with ∆(9)-tetrahydrocannabinol in fatty acid amide hydrolase knockout mice. 2011 Eur. J. Pharmacol. pmid:21300050
Naidoo V et al. A new generation fatty acid amide hydrolase inhibitor protects against kainate-induced excitotoxicity. 2011 J. Mol. Neurosci. pmid:21069475
Gomes FV et al. Facilitation of CB1 receptor-mediated neurotransmission decreases marble burying behavior in mice. 2011 Prog. Neuropsychopharmacol. Biol. Psychiatry pmid:21111767
Cassano T et al. Evaluation of the emotional phenotype and serotonergic neurotransmission of fatty acid amide hydrolase-deficient mice. 2011 Psychopharmacology (Berl.) pmid:21042794
Bari M et al. Characterization of the endocannabinoid system in mouse embryonic stem cells. 2011 Stem Cells Dev. pmid:20446814
Justinová Z et al. Reinforcing and neurochemical effects of cannabinoid CB1 receptor agonists, but not cocaine, are altered by an adenosine A2A receptor antagonist. 2011 Addict Biol pmid:21054689
Long JZ et al. An anatomical and temporal portrait of physiological substrates for fatty acid amide hydrolase. 2011 J. Lipid Res. pmid:21097653
Hofmann ME et al. Cannabinoid receptor agonists potentiate action potential-independent release of GABA in the dentate gyrus through a CB1 receptor-independent mechanism. 2011 J. Physiol. (Lond.) pmid:21646412
Martín-Couce L et al. Development of endocannabinoid-based chemical probes for the study of cannabinoid receptors. 2011 J. Med. Chem. pmid:21675776
Romani R et al. Anandamide and its congeners inhibit human plasma butyrylcholinesterase. Possible new roles for these endocannabinoids? 2011 Biochimie pmid:21664223
Khanna IK and Alexander CW Fatty acid amide hydrolase inhibitors--progress and potential. 2011 CNS Neurol Disord Drug Targets pmid:21631410
Busquets-Garcia A et al. Differential role of anandamide and 2-arachidonoylglycerol in memory and anxiety-like responses. 2011 Biol. Psychiatry pmid:21684528
Warzecha Z et al. Role of sensory nerves in gastroprotective effect of anandamide in rats. 2011 J. Physiol. Pharmacol. pmid:21673369
Sarmad S et al. Depolarizing and calcium-mobilizing stimuli fail to enhance synthesis and release of endocannabinoids from rat brain cerebral cortex slices. 2011 J. Neurochem. pmid:21375532
Munguba H et al. Pre-training anandamide infusion within the basolateral amygdala impairs plus-maze discriminative avoidance task in rats. 2011 Neurobiol Learn Mem pmid:21440651
Stewart JL and McMahon LR The fatty acid amide hydrolase inhibitor URB 597: interactions with anandamide in rhesus monkeys. 2011 Br. J. Pharmacol. pmid:21449917
Howlett AC et al. Endocannabinoid tone versus constitutive activity of cannabinoid receptors. 2011 Br. J. Pharmacol. pmid:21545414
Carr RL et al. Effect of developmental chlorpyrifos exposure, on endocannabinoid metabolizing enzymes, in the brain of juvenile rats. 2011 Toxicol. Sci. pmid:21507991
Qi J et al. Painful pathways induced by TLR stimulation of dorsal root ganglion neurons. 2011 J. Immunol. pmid:21515789
Steiner AA et al. The hypothermic response to bacterial lipopolysaccharide critically depends on brain CB1, but not CB2 or TRPV1, receptors. 2011 J. Physiol. (Lond.) pmid:21486787
Izzo AA and Deutsch DG Unique pathway for anandamide synthesis and liver regeneration. 2011 Proc. Natl. Acad. Sci. U.S.A. pmid:21490298
Chiba T et al. A synthetic cannabinoid, CP55940, inhibits lipopolysaccharide-induced cytokine mRNA expression in a cannabinoid receptor-independent mechanism in rat cerebellar granule cells. 2011 J. Pharm. Pharmacol. pmid:21492165
Huang L et al. Anandamide exerts its antiproliferative actions on cholangiocarcinoma by activation of the GPR55 receptor. 2011 Lab. Invest. pmid:21464819
Dean C Endocannabinoid modulation of sympathetic and cardiovascular responses to acute stress in the periaqueductal gray of the rat. 2011 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:21228344
Ishiguro H et al. Functional polymorphism in the GPR55 gene is associated with anorexia nervosa. 2011 Synapse pmid:20506567
Morera-Herreras T et al. Nigrostriatal denervation changes the effect of cannabinoids on subthalamic neuronal activity in rats. 2011 Psychopharmacology (Berl.) pmid:20959968
Hollis JH et al. The endocannabinoid arachidonylethanolamide attenuates aspects of lipopolysaccharide-induced changes in energy intake, energy expenditure and hypothalamic Fos expression. 2011 J. Neuroimmunol. pmid:21262543
Zschenderlein C et al. Capsaicin-induced changes in LTP in the lateral amygdala are mediated by TRPV1. 2011 PLoS ONE pmid:21249195
Garami A et al. Thermoregulatory phenotype of the Trpv1 knockout mouse: thermoeffector dysbalance with hyperkinesis. 2011 J. Neurosci. pmid:21289181
Wang W et al. Enhancement of apamin-sensitive medium afterhyperpolarization current by anandamide and its role in excitability control in cultured hippocampal neurons. 2011 Neuropharmacology pmid:21272594
Reis GM et al. Endogenous cannabinoid receptor agonist anandamide induces peripheral antinociception by activation of ATP-sensitive K+ channels. 2011 Life Sci. pmid:21277864
Kawahara H et al. Inhibition of fatty acid amide hydrolase unmasks CB1 receptor and TRPV1 channel-mediated modulation of glutamatergic synaptic transmission in midbrain periaqueductal grey. 2011 Br. J. Pharmacol. pmid:21175570
De Petrocellis L et al. Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes. 2011 Br. J. Pharmacol. pmid:21175579
Jumpertz R et al. Central and peripheral endocannabinoids and cognate acylethanolamides in humans: association with race, adiposity, and energy expenditure. 2011 J. Clin. Endocrinol. Metab. pmid:21177788
De Petrocellis L et al. N-palmitoyl-vanillamide (palvanil) is a non-pungent analogue of capsaicin with stronger desensitizing capability against the TRPV1 receptor and anti-hyperalgesic activity. 2011 Pharmacol. Res. pmid:21215315
Kotsikorou E et al. Lipid bilayer molecular dynamics study of lipid-derived agonists of the putative cannabinoid receptor, GPR55. 2011 Chem. Phys. Lipids pmid:21185816
Zaccagnino P et al. Anandamide inhibits oxidative phosphorylation in isolated liver mitochondria. 2011 FEBS Lett. pmid:21187088
Umathe SN et al. Involvement of endocannabinoids in antidepressant and anti-compulsive effect of fluoxetine in mice. 2011 Behav. Brain Res. pmid:21549765
Arias-Carrión O et al. Biochemical modulation of the sleep-wake cycle: endogenous sleep-inducing factors. 2011 J. Neurosci. Res. pmid:21557294
Sordelli MS et al. The effect of anandamide on uterine nitric oxide synthase activity depends on the presence of the blastocyst. 2011 PLoS ONE pmid:21559512
Engel MA et al. Inhibitory CB1 and activating/desensitizing TRPV1-mediated cannabinoid actions on CGRP release in rodent skin. 2011 Neuropeptides pmid:21514666
Gervasi MG et al. Anandamide capacitates bull spermatozoa through CB1 and TRPV1 activation. 2011 PLoS ONE pmid:21347292
Quercioli A et al. Elevated endocannabinoid plasma levels are associated with coronary circulatory dysfunction in obesity. 2011 Eur. Heart J. pmid:21303779
Correa F et al. The endocannabinoid anandamide downregulates IL-23 and IL-12 subunits in a viral model of multiple sclerosis: evidence for a cross-talk between IL-12p70/IL-23 axis and IL-10 in microglial cells. 2011 Brain Behav. Immun. pmid:21310228
Latek D et al. Modeling of ligand binding to G protein coupled receptors: cannabinoid CB1, CB2 and adrenergic β 2 AR. 2011 J Mol Model pmid:21365223
Signorello MG et al. The anandamide effect on NO/cGMP pathway in human platelets. 2011 J. Cell. Biochem. pmid:21328466
Greco R et al. Effects of anandamide in migraine: data from an animal model. 2011 J Headache Pain pmid:21331757
Cippitelli A et al. Endocannabinoid regulation of acute and protracted nicotine withdrawal: effect of FAAH inhibition. 2011 PLoS ONE pmid:22140525
Taylor AH et al. Modulation of the endocannabinoid system in viable and non-viable first trimester pregnancies by pregnancy-related hormones. 2011 Reprod. Biol. Endocrinol. pmid:22126420
Brizzi A et al. Resorcinol-sn-glycerol derivatives: novel 2-arachidonoylglycerol mimetics endowed with high affinity and selectivity for cannabinoid type 1 receptor. 2011 J. Med. Chem. pmid:22044209
Hamtiaux L et al. Increasing antiproliferative properties of endocannabinoids in N1E-115 neuroblastoma cells through inhibition of their metabolism. 2011 PLoS ONE pmid:22046372
Lin QS et al. Hippocampal endocannabinoids play an important role in induction of long-term potentiation and regulation of contextual fear memory formation. 2011 Brain Res. Bull. pmid:21801815
Tsuboi K et al. Enzymatic formation of N-acylethanolamines from N-acylethanolamine plasmalogen through N-acylphosphatidylethanolamine-hydrolyzing phospholipase D-dependent and -independent pathways. 2011 Biochim. Biophys. Acta pmid:21801852
Chianese R et al. Anandamide modulates the expression of GnRH-II and GnRHRs in frog, Rana esculenta, diencephalon. 2011 Gen. Comp. Endocrinol. pmid:21802420
Clugston RD et al. Altered hepatic lipid metabolism in C57BL/6 mice fed alcohol: a targeted lipidomic and gene expression study. 2011 J. Lipid Res. pmid:21856784
Dollery C Investigative clinical pharmacology. 2011 Clin. Pharmacol. Ther. pmid:21862965
Kopczyńska B et al. Anandamide enhances expression of heat shock proteins Hsp70 and Hsp25 in rat lungs. 2011 Eur. J. Pharmacol. pmid:21756900
Yoshino H et al. Postsynaptic diacylglycerol lipase mediates retrograde endocannabinoid suppression of inhibition in mouse prefrontal cortex. 2011 J. Physiol. (Lond.) pmid:21807615
Theile JW and Cummins TR Inhibition of Navβ4 peptide-mediated resurgent sodium currents in Nav1.7 channels by carbamazepine, riluzole, and anandamide. 2011 Mol. Pharmacol. pmid:21788423
Ndong C et al. Cloning and pharmacological characterization of the dog cannabinoid CBâ‚‚receptor. 2011 Eur. J. Pharmacol. pmid:21871882
Altinsoy A et al. A cannabinoid ligand, anandamide, exacerbates endotoxin-induced uveitis in rabbits. 2011 J Ocul Pharmacol Ther pmid:21848425
Khasabova IA et al. Increasing 2-arachidonoyl glycerol signaling in the periphery attenuates mechanical hyperalgesia in a model of bone cancer pain. 2011 Pharmacol. Res. pmid:21440630
Zoerner AA et al. Allergen challenge increases anandamide in bronchoalveolar fluid of patients with allergic asthma. 2011 Clin. Pharmacol. Ther. pmid:21716266
Brailoiu GC et al. Intracellular cannabinoid type 1 (CB1) receptors are activated by anandamide. 2011 J. Biol. Chem. pmid:21719698
Catanzaro G et al. Effect of capacitation on the endocannabinoid system of mouse sperm. 2011 Mol. Cell. Endocrinol. pmid:21723369