Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

Cross Reference

Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Sleep Disorders, Intrinsic D020919 1 associated lipids
Headache Disorders, Secondary D051271 1 associated lipids
Somatosensory Disorders D020886 1 associated lipids
Orthostatic Intolerance D054971 1 associated lipids
Ocular Hypotension D015814 2 associated lipids
Vascular System Injuries D057772 2 associated lipids
Amnesia, Anterograde D020324 2 associated lipids
Substance-Related Disorders D019966 2 associated lipids
Bulimia D002032 3 associated lipids
Acute Pain D059787 3 associated lipids
Per page 10 20 50 100 | Total 105

PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

Download all related citations
Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Marco EM et al. Long-term consequences of URB597 administration during adolescence on cannabinoid CB1 receptor binding in brain areas. 2009 Brain Res. pmid:19133243
Ho WS and Gardiner SM Acute hypertension reveals depressor and vasodilator effects of cannabinoids in conscious rats. 2009 Br. J. Pharmacol. pmid:19133994
Doroshenko P and Renaud LP Acid-sensitive TASK-like K+ conductances contribute to resting membrane potential and to orexin-induced membrane depolarization in rat thalamic paraventricular nucleus neurons. 2009 Neuroscience pmid:19135504
Koethe D et al. Sleep deprivation increases oleoylethanolamide in human cerebrospinal fluid. 2009 J Neural Transm pmid:19137236
Ferreira SG et al. N-acyldopamines control striatal input terminals via novel ligand-gated cation channels. 2009 Neuropharmacology pmid:19101577
Ozalp A and Barroso B Simultaneous quantitative analysis of N-acylethanolamides in clinical samples. 2009 Anal. Biochem. pmid:19665986
Aquila S et al. A new role of anandamide in human sperm: focus on metabolism. 2009 J. Cell. Physiol. pmid:19492411
Kingsley PJ and Marnett LJ Analysis of endocannabinoids, their congeners and COX-2 metabolites. 2009 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:19505857
Dowie MJ et al. Altered CB1 receptor and endocannabinoid levels precede motor symptom onset in a transgenic mouse model of Huntington's disease. 2009 Neuroscience pmid:19524019
Wise LE et al. Fatty acid amide hydrolase (FAAH) knockout mice exhibit enhanced acquisition of an aversive, but not of an appetitive, Barnes maze task. 2009 Neurobiol Learn Mem pmid:19524055
Maeda N et al. Increased serum anandamide level at ruptured plaque site in patients with acute myocardial infarction. 2009 Fundam Clin Pharmacol pmid:19527302
Straiker A and Mackie K Cannabinoid signaling in inhibitory autaptic hippocampal neurons. 2009 Neuroscience pmid:19501632
Kinsey SG et al. Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain. 2009 J. Pharmacol. Exp. Ther. pmid:19502530
Brighton PJ et al. Characterization of anandamide-stimulated cannabinoid receptor signaling in human ULTR myometrial smooth muscle cells. 2009 Mol. Endocrinol. pmid:19477951
Oddi S et al. Molecular identification of albumin and Hsp70 as cytosolic anandamide-binding proteins. 2009 Chem. Biol. pmid:19481477
Reis GM et al. Opioid receptor and NO/cGMP pathway as a mechanism of peripheral antinociceptive action of the cannabinoid receptor agonist anandamide. 2009 Life Sci. pmid:19576231
Umathe SN et al. Endocannabinoids mediate anxiolytic-like effect of acetaminophen via CB1 receptors. 2009 Prog. Neuropsychopharmacol. Biol. Psychiatry pmid:19580839
Murakami T et al. Antimicrobial cathelicidin polypeptide CAP11 suppresses the production and release of septic mediators in D-galactosamine-sensitized endotoxin shock mice. 2009 Int. Immunol. pmid:19556302
Palandra J et al. Endogenous ethanolamide analysis in human plasma using HPLC tandem MS with electrospray ionization. 2009 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:19535304
Fonseca BM et al. Anandamide-induced cell death: dual effects in primary rat decidual cell cultures. 2009 Placenta pmid:19560819
Snider NT et al. A cytochrome P450-derived epoxygenated metabolite of anandamide is a potent cannabinoid receptor 2-selective agonist. 2009 Mol. Pharmacol. pmid:19171674
Tóth A et al. Anandamide and the vanilloid receptor (TRPV1). 2009 Vitam. Horm. pmid:19647120
Pasquariello N et al. Regulation of gene transcription and keratinocyte differentiation by anandamide. 2009 Vitam. Horm. pmid:19647122
Alpini G and Demorrow S Changes in the endocannabinoid system may give insight into new and effective treatments for cancer. 2009 Vitam. Horm. pmid:19647123
Astarita G et al. Targeted lipidomics as a tool to investigate endocannabinoid function. 2009 Int. Rev. Neurobiol. pmid:19607960
Francavilla F et al. Characterization of the endocannabinoid system in human spermatozoa and involvement of transient receptor potential vanilloid 1 receptor in their fertilizing ability. 2009 Endocrinology pmid:19608651
Centonze D et al. Altered anandamide degradation in attention-deficit/hyperactivity disorder. 2009 Neurology pmid:19398708
Liu H et al. Endocannabinoids anandamide and its cannabinoid receptors in liver fibrosis after murine schistosomiasis. 2009 J. Huazhong Univ. Sci. Technol. Med. Sci. pmid:19399401
Mazzola C et al. Fatty acid amide hydrolase (FAAH) inhibition enhances memory acquisition through activation of PPAR-alpha nuclear receptors. 2009 Learn. Mem. pmid:19403796
Shen Y et al. A transient receptor potential-like channel mediates synaptic transmission in rod bipolar cells. 2009 J. Neurosci. pmid:19439586
Ahn K et al. Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain. 2009 Chem. Biol. pmid:19389627
Yates ML and Barker EL Inactivation and biotransformation of the endogenous cannabinoids anandamide and 2-arachidonoylglycerol. 2009 Mol. Pharmacol. pmid:19389920
Miyato H et al. Pharmacological synergism between cannabinoids and paclitaxel in gastric cancer cell lines. 2009 J. Surg. Res. pmid:19394652
Hill MN et al. Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress. 2009 Psychoneuroendocrinology pmid:19394765
Chen L et al. Endogenous anandamide and cannabinoid receptor-2 contribute to electroacupuncture analgesia in rats. 2009 J Pain pmid:19409856
Balas L et al. Total synthesis of photoactivatable or fluorescent anandamide probes: novel bioactive compounds with angiogenic activity. 2009 J. Med. Chem. pmid:19161308
Trezza V and Vanderschuren LJ Divergent effects of anandamide transporter inhibitors with different target selectivity on social play behavior in adolescent rats. 2009 J. Pharmacol. Exp. Ther. pmid:18948500
Carney ST et al. Cannabinoid regulation of nitric oxide synthase I (nNOS) in neuronal cells. 2009 J Neuroimmune Pharmacol pmid:19365734
Gardiner SM et al. Factors influencing the regional haemodynamic responses to methanandamide and anandamide in conscious rats. 2009 Br. J. Pharmacol. pmid:19702785
Gervasi MG et al. The endocannabinoid system in bull sperm and bovine oviductal epithelium: role of anandamide in sperm-oviduct interaction. 2009 Reproduction pmid:19042982
Guindon J and Hohmann AG The endocannabinoid system and pain. 2009 CNS Neurol Disord Drug Targets pmid:19839937
Karaliota S et al. Anandamide increases the differentiation of rat adipocytes and causes PPARgamma and CB1 receptor upregulation. 2009 Obesity (Silver Spring) pmid:19543211
Marco EM and Viveros MP The critical role of the endocannabinoid system in emotional homeostasis: avoiding excess and deficiencies. 2009 Mini Rev Med Chem pmid:19929814
Vercelli CA et al. Endocannabinoid system and nitric oxide are involved in the deleterious effects of lipopolysaccharide on murine decidua. 2009 Placenta pmid:19428101
Mendiguren A and Pineda J Effect of the CB(1) receptor antagonists rimonabant and AM251 on the firing rate of dorsal raphe nucleus neurons in rat brain slices. 2009 Br. J. Pharmacol. pmid:19845674
Guindon J and Beaulieu P The role of the endogenous cannabinoid system in peripheral analgesia. 2009 Curr Mol Pharmacol pmid:20021453
Fonseca BM et al. Spatio-temporal expression patterns of anandamide-binding receptors in rat implantation sites: evidence for a role of the endocannabinoid system during the period of placental development. 2009 Reprod. Biol. Endocrinol. pmid:19860893
Bradshaw HB et al. The endocannabinoid anandamide is a precursor for the signaling lipid N-arachidonoyl glycine by two distinct pathways. 2009 BMC Biochem. pmid:19460156
Li Q et al. Electrophysiological effects of anandamide on rat myocardium. 2009 Br. J. Pharmacol. pmid:20050190
Hiley CR Endocannabinoids and the heart. 2009 J. Cardiovasc. Pharmacol. pmid:19276990
Gratzke C et al. Distribution and function of cannabinoid receptors 1 and 2 in the rat, monkey and human bladder. 2009 J. Urol. pmid:19237169
El-Talatini MR et al. Localisation and function of the endocannabinoid system in the human ovary. 2009 PLoS ONE pmid:19238202
Parker LA et al. The FAAH inhibitor URB-597 interferes with cisplatin- and nicotine-induced vomiting in the Suncus murinus (house musk shrew). 2009 Physiol. Behav. pmid:19239915
Schlosburg JE et al. Targeting fatty acid amide hydrolase (FAAH) to treat pain and inflammation. 2009 AAPS J pmid:19184452
Navarrete CM et al. Opposite effects of anandamide and N-arachidonoyl dopamine in the regulation of prostaglandin E and 8-iso-PGF formation in primary glial cells. 2009 J. Neurochem. pmid:19200337
Tang B et al. Endothelin-1 inhibits background two-pore domain channel TASK-1 in primary human pulmonary artery smooth muscle cells. 2009 Am. J. Respir. Cell Mol. Biol. pmid:19188660
Ribeiro ML et al. 17beta-oestradiol and progesterone regulate anandamide synthesis in the rat uterus. 2009 Reprod. Biomed. Online pmid:19192341
Vural IM et al. Functional characterization of nonadrenergic noncholinergic neurotransmitter release via endocannabinoids: an in vitro study in rabbit corpus cavernosum. 2009 J Sex Med pmid:19175867
Garcia-Ovejero D et al. The endocannabinoid system is modulated in response to spinal cord injury in rats. 2009 Neurobiol. Dis. pmid:18930143
McMahon LR Apparent affinity estimates of rimonabant in combination with anandamide and chemical analogs of anandamide in rhesus monkeys discriminating Delta9-tetrahydrocannabinol. 2009 Psychopharmacology (Berl.) pmid:18592221
McCue JM et al. In vitro synthesis of arachidonoyl amino acids by cytochrome c. 2009 Prostaglandins Other Lipid Mediat. pmid:19683594
Appendino G et al. Conformationally constrained fatty acid ethanolamides as cannabinoid and vanilloid receptor probes. 2009 J. Med. Chem. pmid:19361197
El-Talatini MR et al. Fluctuation in anandamide levels from ovulation to early pregnancy in in-vitro fertilization-embryo transfer women, and its hormonal regulation. 2009 Hum. Reprod. pmid:19363040
Brizzi A et al. New resorcinol-anandamide "hybrids" as potent cannabinoid receptor ligands endowed with antinociceptive activity in vivo. 2009 J. Med. Chem. pmid:19331413
Koethe D et al. Anandamide elevation in cerebrospinal fluid in initial prodromal states of psychosis. 2009 Br J Psychiatry pmid:19336792
Mangieri RA et al. An endocannabinoid signal associated with desire for alcohol is suppressed in recently abstinent alcoholics. 2009 Psychopharmacology (Berl.) pmid:19343330
Potenzieri C et al. Excitation of cutaneous C nociceptors by intraplantar administration of anandamide. 2009 Brain Res. pmid:19285051
De Petrocellis L and Di Marzo V An introduction to the endocannabinoid system: from the early to the latest concepts. 2009 Best Pract. Res. Clin. Endocrinol. Metab. pmid:19285257
Borrelli F and Izzo AA Role of acylethanolamides in the gastrointestinal tract with special reference to food intake and energy balance. 2009 Best Pract. Res. Clin. Endocrinol. Metab. pmid:19285259
Bermúdez-Silva FJ et al. The role of the pancreatic endocannabinoid system in glucose metabolism. 2009 Best Pract. Res. Clin. Endocrinol. Metab. pmid:19285263
Kaczocha M et al. Identification of intracellular carriers for the endocannabinoid anandamide. 2009 Proc. Natl. Acad. Sci. U.S.A. pmid:19307565
Alenmyr L et al. TRPV1-mediated itch in seasonal allergic rhinitis. 2009 Allergy pmid:19220220
García-García F et al. Sleep-inducing factors. 2009 CNS Neurol Disord Drug Targets pmid:19689305
Pasquariello N et al. Characterization of the endocannabinoid system in human neuronal cells and proteomic analysis of anandamide-induced apoptosis. 2009 J. Biol. Chem. pmid:19690173
Schroeder C et al. Circulating endocannabinoid concentrations during orthostatic stress. 2009 Clin. Auton. Res. pmid:19756829
Tuboly G et al. The antinociceptive interaction of anandamide and adenosine at the spinal level. 2009 Pharmacol. Biochem. Behav. pmid:18760296
Panlilio LV et al. Anandamide-induced behavioral disruption through a vanilloid-dependent mechanism in rats. 2009 Psychopharmacology (Berl.) pmid:19015836
De Petrocellis L et al. Chemical synthesis, pharmacological characterization, and possible formation in unicellular fungi of 3-hydroxy-anandamide. 2009 J. Lipid Res. pmid:19017617
Tuboly G et al. Antinociceptive interactions between anandamide and endomorphin-1 at the spinal level. 2009 Clin. Exp. Pharmacol. Physiol. pmid:19018802
Schacht JP et al. Intermediate cannabis dependence phenotypes and the FAAH C385A variant: an exploratory analysis. 2009 Psychopharmacology (Berl.) pmid:19002671
Araújo JR et al. Effect of cannabinoids upon the uptake of folic acid by BeWo cells. 2009 Pharmacology pmid:19145103
Van Dross RT Metabolism of anandamide by COX-2 is necessary for endocannabinoid-induced cell death in tumorigenic keratinocytes. 2009 Mol. Carcinog. pmid:19148897
Hydock DS et al. Anandamide preserves cardiac function and geometry in an acute doxorubicin cardiotoxicity rat model. 2009 J. Cardiovasc. Pharmacol. Ther. pmid:19129423
Lin YS et al. Sensitization of capsaicin-sensitive lung vagal afferents by anandamide in rats: role of transient receptor potential vanilloid 1 receptors. 2009 J. Appl. Physiol. pmid:19131477
Kurjak M et al. Differential stimulatory effects of cannabinoids on VIP release and NO synthase activity in synaptosomal fractions from rat ileum. 2008 Oct-Dec Neuropeptides pmid:18829105
Lissoni P et al. The endocannabinoid anandamide neither impairs in vitro T-cell function nor induces regulatory T-cell generation. 2008 Nov-Dec Anticancer Res. pmid:19189659
Sakamoto Y et al. Effectiveness of continuous hemodiafiltration using a polymethylmethacrylate membrane hemofilter after polymyxin B-immobilized fiber column therapy of septic shock. 2008 Jan-Feb ASAIO J. pmid:18204329
Snider NT et al. The endocannabinoid anandamide is a substrate for the human polymorphic cytochrome P450 2D6. 2008 J. Pharmacol. Exp. Ther. pmid:18698000
Moreira FA et al. Reduced anxiety-like behaviour induced by genetic and pharmacological inhibition of the endocannabinoid-degrading enzyme fatty acid amide hydrolase (FAAH) is mediated by CB1 receptors. 2008 Neuropharmacology pmid:17709120
Di Marzo V and Maccarrone M FAAH and anandamide: is 2-AG really the odd one out? 2008 Trends Pharmacol. Sci. pmid:18394720
Kaufmann I et al. Anandamide and neutrophil function in patients with fibromyalgia. 2008 Psychoneuroendocrinology pmid:18395993
Hegde VL et al. Attenuation of experimental autoimmune hepatitis by exogenous and endogenous cannabinoids: involvement of regulatory T cells. 2008 Mol. Pharmacol. pmid:18388242
Farrell EK and Merkler DJ Biosynthesis, degradation and pharmacological importance of the fatty acid amides. 2008 Drug Discov. Today pmid:18598910
Yao F et al. Development of novel tail-modified anandamide analogs. 2008 Bioorg. Med. Chem. Lett. pmid:18723350
Kase Y et al. Removal of 2-arachidonylglycerol by direct hemoperfusion therapy with polymyxin B immobilized fibers benefits patients with septic shock. 2008 Ther Apher Dial pmid:18937720
Kamei J et al. [Sensitization of cough sensitivity through activation of C-and/or Adelta fibers]. 2008 Nippon Yakurigaku Zasshi pmid:18552444
Thors L et al. Inhibition of fatty acid amide hydrolase by kaempferol and related naturally occurring flavonoids. 2008 Br. J. Pharmacol. pmid:18552875
Ellgren M et al. Dynamic changes of the endogenous cannabinoid and opioid mesocorticolimbic systems during adolescence: THC effects. 2008 Eur Neuropsychopharmacol pmid:18674887
DeMorrow S et al. Anandamide inhibits cholangiocyte hyperplastic proliferation via activation of thioredoxin 1/redox factor 1 and AP-1 activation. 2008 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:18096608
Rubino T et al. Role in anxiety behavior of the endocannabinoid system in the prefrontal cortex. 2008 Cereb. Cortex pmid:17921459