Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Alzheimer Disease D000544 76 associated lipids
Anorexia D000855 8 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Ataxia D001259 20 associated lipids
Urinary Bladder Diseases D001745 4 associated lipids
Body Weight D001835 333 associated lipids
Bradycardia D001919 13 associated lipids
Brain Concussion D001924 5 associated lipids
Brain Damage, Chronic D001925 6 associated lipids
Brain Edema D001929 20 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Fowler CJ et al. Inhibition of anandamide hydrolysis by the enantiomers of ibuprofen, ketorolac, and flurbiprofen. 1999 Arch. Biochem. Biophys. pmid:9989926
Piomelli D et al. Endogenous cannabinoid signaling. 1998 Neurobiol. Dis. pmid:9974178
Di Marzo V and Deutsch DG Biochemistry of the endogenous ligands of cannabinoid receptors. 1998 Neurobiol. Dis. pmid:9974173
Navarro M and Rodríguez de Fonseca F The neurobiology of cannabinoid transmission: from anandamide signaling to higher cerebral functions and disease. 1998 Neurobiol. Dis. pmid:9974172
Lu R et al. Cloning of the human kidney PAH transporter: narrow substrate specificity and regulation by protein kinase C. 1999 Am. J. Physiol. pmid:9950961
Goparaju SK et al. Enzymes of porcine brain hydrolyzing 2-arachidonoylglycerol, an endogenous ligand of cannabinoid receptors. 1999 Biochem. Pharmacol. pmid:9933030
Wagner JA et al. Mesenteric vasodilation mediated by endothelial anandamide receptors. 1999 Hypertension pmid:9931142
Basavarajappa BS and Hungund BL Chronic ethanol increases the cannabinoid receptor agonist anandamide and its precursor N-arachidonoylphosphatidylethanolamine in SK-N-SH cells. 1999 J. Neurochem. pmid:9930723
Beltramo M and Piomelli D Anandamide transport inhibition by the vanilloid agonist olvanil. 1999 Eur. J. Pharmacol. pmid:9920187
Sugiura T et al. Evidence that the cannabinoid CB1 receptor is a 2-arachidonoylglycerol receptor. Structure-activity relationship of 2-arachidonoylglycerol, ether-linked analogues, and related compounds. 1999 J. Biol. Chem. pmid:9915812
Lin S et al. Novel analogues of arachidonylethanolamide (anandamide): affinities for the CB1 and CB2 cannabinoid receptors and metabolic stability. 1998 J. Med. Chem. pmid:9876105
Ueda N et al. A hydrolase enzyme inactivating endogenous ligands for cannabinoid receptors. 1998 J. Med. Invest. pmid:9864962
Bonhaus DW et al. Dual activation and inhibition of adenylyl cyclase by cannabinoid receptor agonists: evidence for agonist-specific trafficking of intracellular responses. 1998 J. Pharmacol. Exp. Ther. pmid:9864268
Stahl SM Getting stoned without inhaling: anandamide is the brain's natural marijuana. 1998 J Clin Psychiatry pmid:9862600
Mallet PE and Beninger RJ The cannabinoid CB1 receptor antagonist SR141716A attenuates the memory impairment produced by delta9-tetrahydrocannabinol or anandamide. 1998 Psychopharmacology (Berl.) pmid:9862397
Pate DW et al. Effect of the CB1 receptor antagonist, SR141716A, on cannabinoid-induced ocular hypotension in normotensive rabbits. 1998 Life Sci. pmid:9851310
Castellano C et al. The effects of anandamide on memory consolidation in mice involve both D1 and D2 dopamine receptors. 1997 Behav Pharmacol pmid:9832956
Mechoulam R et al. Endocannabinoids. 1998 Eur. J. Pharmacol. pmid:9831287
Maccarrone M et al. Anandamide hydrolysis by human cells in culture and brain. 1998 J. Biol. Chem. pmid:9822713
Barnett-Norris J et al. Exploration of biologically relevant conformations of anandamide, 2-arachidonylglycerol, and their analogues using conformational memories. 1998 J. Med. Chem. pmid:9822555
Murillo-Rodríguez E et al. Anandamide modulates sleep and memory in rats. 1998 Brain Res. pmid:9813364
Aceto MD et al. Anandamide, an endogenous cannabinoid, has a very low physical dependence potential. 1998 J. Pharmacol. Exp. Ther. pmid:9808686
Levin M and Mercola M Gap junctions are involved in the early generation of left-right asymmetry. 1998 Dev. Biol. pmid:9806775
White R and Hiley CR The actions of some cannabinoid receptor ligands in the rat isolated mesenteric artery. 1998 Br. J. Pharmacol. pmid:9806337
Stein EA et al. Selective effects of the endogenous cannabinoid arachidonylethanolamide (anandamide) on regional cerebral blood flow in the rat. 1998 Neuropsychopharmacology pmid:9803424
Di Marzo V et al. Interactions between synthetic vanilloids and the endogenous cannabinoid system. 1998 FEBS Lett. pmid:9801167
Lichtman AH et al. Effects of SR 141716A after acute or chronic cannabinoid administration in dogs. 1998 Eur. J. Pharmacol. pmid:9797029
Pestonjamasp VK and Burstein SH Anandamide synthesis is induced by arachidonate mobilizing agonists in cells of the immune system. 1998 Biochim. Biophys. Acta pmid:9795237
Tong W et al. Derivation of a pharmacophore model for anandamide using constrained conformational searching and comparative molecular field analysis. 1998 J. Med. Chem. pmid:9784095
Jaggar SI et al. The endogenous cannabinoid anandamide, but not the CB2 ligand palmitoylethanolamide, prevents the viscero-visceral hyper-reflexia associated with inflammation of the rat urinary bladder. 1998 Neurosci. Lett. pmid:9774165
Wiley JL et al. Evaluation of cannabimimetic effects of structural analogs of anandamide in rats. 1998 Eur. J. Pharmacol. pmid:9760024
Stengel PW et al. Pulmonary actions of anandamide, an endogenous cannabinoid receptor agonist, in guinea pigs. 1998 Eur. J. Pharmacol. pmid:9754939
Schneider U et al. Cannabinoid/anandamide system and schizophrenia: is there evidence for association? 1998 Pharmacopsychiatry pmid:9754842
McGregor IS et al. A comparison of delta 9-THC and anandamide induced c-fos expression in the rat forebrain. 1998 Brain Res. pmid:9748483
Molina-Holgado F et al. The endogenous cannabinoid anandamide potentiates interleukin-6 production by astrocytes infected with Theiler's murine encephalomyelitis virus by a receptor-mediated pathway. 1998 FEBS Lett. pmid:9738948
Fields HL and Meng ID Watching the pot boil. 1998 Nat. Med. pmid:9734389
Welch SP et al. Differential blockade of the antinociceptive effects of centrally administered cannabinoids by SR141716A. 1998 J. Pharmacol. Exp. Ther. pmid:9732392
Fulton D and Quilley J Evidence against anandamide as the hyperpolarizing factor mediating the nitric oxide-independent coronary vasodilator effect of bradykinin in the rat. 1998 J. Pharmacol. Exp. Ther. pmid:9732371
Berdyshev E et al. Effects of cannabinoid receptor ligands on LPS-induced pulmonary inflammation in mice. 1998 Life Sci. pmid:9718090
Childers SR and Breivogel CS Cannabis and endogenous cannabinoid systems. 1998 Jun-Jul Drug Alcohol Depend pmid:9716939
Varga K et al. Platelet- and macrophage-derived endogenous cannabinoids are involved in endotoxin-induced hypotension. 1998 FASEB J. pmid:9707176
Bisogno T et al. Arachidonoylserotonin and other novel inhibitors of fatty acid amide hydrolase. 1998 Biochem. Biophys. Res. Commun. pmid:9703957
Jaggar SI et al. The anti-hyperalgesic actions of the cannabinoid anandamide and the putative CB2 receptor agonist palmitoylethanolamide in visceral and somatic inflammatory pain. 1998 Pain pmid:9696473
Bisogno T et al. Biosynthesis and degradation of bioactive fatty acid amides in human breast cancer and rat pheochromocytoma cells--implications for cell proliferation and differentiation. 1998 Eur. J. Biochem. pmid:9688276
Stefano GB et al. Macrophage behavior associated with acute and chronic exposure to HIV GP120, morphine and anandamide: endothelial implications. 1998 Int. J. Cardiol. pmid:9687087
Calignano A et al. Control of pain initiation by endogenous cannabinoids. 1998 Nature pmid:9685157
Qin C et al. Determination of anandamide amidase activity using ultraviolet-active amine derivatives and reverse-phase high-performance liquid chromatography. 1998 Anal. Biochem. pmid:9683506
van Zadelhoff G et al. With anandamide as substrate plant 5-lipoxygenases behave like 11-lipoxygenases. 1998 Biochem. Biophys. Res. Commun. pmid:9675081
Patel NA et al. Arachidonylethanolamide (AEA) activation of FOS proto-oncogene protein immunoreactivity in the rat brain. 1998 Brain Res. pmid:9666136
Edgemond WS et al. Human platelets and polymorphonuclear leukocytes synthesize oxygenated derivatives of arachidonylethanolamide (anandamide): their affinities for cannabinoid receptors and pathways of inactivation. 1998 Mol. Pharmacol. pmid:9658204