| MeSH term | MeSH ID | Detail |
|---|---|---|
| Alzheimer Disease | D000544 | 76 associated lipids |
| Anorexia | D000855 | 8 associated lipids |
| Arthritis, Experimental | D001169 | 24 associated lipids |
| Ataxia | D001259 | 20 associated lipids |
| Urinary Bladder Diseases | D001745 | 4 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Bradycardia | D001919 | 13 associated lipids |
| Brain Concussion | D001924 | 5 associated lipids |
| Brain Damage, Chronic | D001925 | 6 associated lipids |
| Brain Edema | D001929 | 20 associated lipids |
Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Neelamegan D et al. | Identification and recombinant expression of anandamide hydrolyzing enzyme from Dictyostelium discoideum. | 2012 | BMC Microbiol. | pmid:22730904 |
| Wang ZJ et al. | Cannabinoid receptor-mediated regulation of neuronal activity and signaling in glomeruli of the main olfactory bulb. | 2012 | J. Neurosci. | pmid:22723687 |
| Leweke FM | Anandamide dysfunction in prodromal and established psychosis. | 2012 | Curr. Pharm. Des. | pmid:22716147 |
| Gebeh AK et al. | Ectopic pregnancy is associated with high anandamide levels and aberrant expression of FAAH and CB1 in fallopian tubes. | 2012 | J. Clin. Endocrinol. Metab. | pmid:22701012 |
| Gunduz-Cinar O et al. | Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity. | 2013 | Mol. Psychiatry | pmid:22688188 |
| Ritter JK et al. | Production and actions of the anandamide metabolite prostamide E2 in the renal medulla. | 2012 | J. Pharmacol. Exp. Ther. | pmid:22685343 |
| Forsell PK et al. | Metabolism of anandamide into eoxamides by 15-lipoxygenase-1 and glutathione transferases. | 2012 | Lipids | pmid:22684912 |
| Lipina C et al. | New vistas for treatment of obesity and diabetes? Endocannabinoid signalling and metabolism in the modulation of energy balance. | 2012 | Bioessays | pmid:22674489 |
| Chianese R et al. | Anandamide regulates the expression of GnRH1, GnRH2, and GnRH-Rs in frog testis. | 2012 | Am. J. Physiol. Endocrinol. Metab. | pmid:22669247 |
| Tsumura M et al. | TRPV1-mediated calcium signal couples with cannabinoid receptors and sodium-calcium exchangers in rat odontoblasts. | 2012 | Cell Calcium | pmid:22656960 |
| Hernangómez M et al. | CD200-CD200R1 interaction contributes to neuroprotective effects of anandamide on experimentally induced inflammation. | 2012 | Glia | pmid:22653796 |
| Chicca A et al. | The antinociceptive triterpene β-amyrin inhibits 2-arachidonoylglycerol (2-AG) hydrolysis without directly targeting cannabinoid receptors. | 2012 | Br. J. Pharmacol. | pmid:22646533 |
| Baranowska-Kuczko M et al. | Endothelium-dependent mechanisms of the vasodilatory effect of the endocannabinoid, anandamide, in the rat pulmonary artery. | 2012 | Pharmacol. Res. | pmid:22627170 |
| Vinod KY et al. | Dysfunction in fatty acid amide hydrolase is associated with depressive-like behavior in Wistar Kyoto rats. | 2012 | PLoS ONE | pmid:22606285 |
| Miyashita K et al. | Anandamide induces matrix metalloproteinase-2 production through cannabinoid-1 receptor and transient receptor potential vanilloid-1 in human dental pulp cells in culture. | 2012 | J Endod | pmid:22595113 |
| Okine BN et al. | Lack of effect of chronic pre-treatment with the FAAH inhibitor URB597 on inflammatory pain behaviour: evidence for plastic changes in the endocannabinoid system. | 2012 | Br. J. Pharmacol. | pmid:22595021 |
| Khasabova IA et al. | Cannabinoid type-1 receptor reduces pain and neurotoxicity produced by chemotherapy. | 2012 | J. Neurosci. | pmid:22593077 |
| Haruta C | [Effects of anandamide on IL-11 production through the TRPV1 of human periodontal ligament cells]. | 2012 | Kokubyo Gakkai Zasshi | pmid:22568077 |
| Sordelli MS et al. | Cyclooxygenase-2 prostaglandins mediate anandamide-inhibitory action on nitric oxide synthase activity in the receptive rat uterus. | 2012 | Eur. J. Pharmacol. | pmid:22554772 |
| Gould GG et al. | Acetaminophen differentially enhances social behavior and cortical cannabinoid levels in inbred mice. | 2012 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:22542870 |
| Tong S et al. | Diagnostic accuracy of maternal serum macrophage inhibitory cytokine-1 and pregnancy-associated plasma protein-A at 6-10 weeks of gestation to predict miscarriage. | 2012 | Obstet Gynecol | pmid:22525911 |
| Katona I and Freund TF | Multiple functions of endocannabinoid signaling in the brain. | 2012 | Annu. Rev. Neurosci. | pmid:22524785 |
| Caprioli A et al. | The novel reversible fatty acid amide hydrolase inhibitor ST4070 increases endocannabinoid brain levels and counteracts neuropathic pain in different animal models. | 2012 | J. Pharmacol. Exp. Ther. | pmid:22514334 |
| Miller LL et al. | Effects of alterations in cannabinoid signaling, alone and in combination with morphine, on pain-elicited and pain-suppressed behavior in mice. | 2012 | J. Pharmacol. Exp. Ther. | pmid:22514333 |
| Czifra G et al. | Endocannabinoids regulate growth and survival of human eccrine sweat gland-derived epithelial cells. | 2012 | J. Invest. Dermatol. | pmid:22513781 |
| Tamaki C et al. | Anandamide induces endothelium-dependent vasoconstriction and CGRPergic nerve-mediated vasodilatation in the rat mesenteric vascular bed. | 2012 | J. Pharmacol. Sci. | pmid:22510966 |
| Xiong W et al. | A common molecular basis for exogenous and endogenous cannabinoid potentiation of glycine receptors. | 2012 | J. Neurosci. | pmid:22496565 |
| Simpson CD et al. | A genome wide shRNA screen identifies α/β hydrolase domain containing 4 (ABHD4) as a novel regulator of anoikis resistance. | 2012 | Apoptosis | pmid:22488300 |
| Sharir H et al. | The endocannabinoids anandamide and virodhamine modulate the activity of the candidate cannabinoid receptor GPR55. | 2012 | J Neuroimmune Pharmacol | pmid:22454039 |
| Petrovszki Z et al. | The effects of peptide and lipid endocannabinoids on arthritic pain at the spinal level. | 2012 | Anesth. Analg. | pmid:22451592 |
| Kenessey I et al. | Revisiting CB1 receptor as drug target in human melanoma. | 2012 | Pathol. Oncol. Res. | pmid:22447182 |
| Andrianova EL et al. | In vitro effects of anandamide and prostamide e2 on normal and transformed nerve cells. | 2011 | Bull. Exp. Biol. Med. | pmid:22442796 |
| Monteleone P et al. | Hedonic eating is associated with increased peripheral levels of ghrelin and the endocannabinoid 2-arachidonoyl-glycerol in healthy humans: a pilot study. | 2012 | J. Clin. Endocrinol. Metab. | pmid:22442280 |
| Dubreucq S et al. | Genetic dissection of the role of cannabinoid type-1 receptors in the emotional consequences of repeated social stress in mice. | 2012 | Neuropsychopharmacology | pmid:22434220 |
| Pucci M et al. | Endocannabinoids stimulate human melanogenesis via type-1 cannabinoid receptor. | 2012 | J. Biol. Chem. | pmid:22431736 |
| Romano MR and Lograno MD | Involvement of the peroxisome proliferator-activated receptor (PPAR) alpha in vascular response of endocannabinoids in the bovine ophthalmic artery. | 2012 | Eur. J. Pharmacol. | pmid:22429572 |
| Lisboa SF and Guimarães FS | Differential role of CB1 and TRPV1 receptors on anandamide modulation of defensive responses induced by nitric oxide in the dorsolateral periaqueductal gray. | 2012 | Neuropharmacology | pmid:22394688 |
| Fogaça MV et al. | Fine-tuning of defensive behaviors in the dorsal periaqueductal gray by atypical neurotransmitters. | 2012 | Braz. J. Med. Biol. Res. | pmid:22392189 |
| Manna SS and Umathe SN | Involvement of transient receptor potential vanilloid type 1 channels in the pro-convulsant effect of anandamide in pentylenetetrazole-induced seizures. | 2012 | Epilepsy Res. | pmid:22386872 |
| Gatta L et al. | Discovery of prostamide F2α and its role in inflammatory pain and dorsal horn nociceptive neuron hyperexcitability. | 2012 | PLoS ONE | pmid:22363560 |
| Osycka-Salut C et al. | Anandamide induces sperm release from oviductal epithelia through nitric oxide pathway in bovines. | 2012 | PLoS ONE | pmid:22363468 |
| Alvheim AR et al. | Dietary linoleic acid elevates endogenous 2-AG and anandamide and induces obesity. | 2012 | Obesity (Silver Spring) | pmid:22334255 |
| Zhang X et al. | Agonist-dependent potentiation of vanilloid receptor transient receptor potential vanilloid type 1 function by stilbene derivatives. | 2012 | Mol. Pharmacol. | pmid:22328719 |
| Newberry EP et al. | Decreased body weight and hepatic steatosis with altered fatty acid ethanolamide metabolism in aged L-Fabp -/- mice. | 2012 | J. Lipid Res. | pmid:22327204 |
| McLaughlin RJ et al. | Prefrontal cortical anandamide signaling coordinates coping responses to stress through a serotonergic pathway. | 2012 | Eur Neuropsychopharmacol | pmid:22325231 |
| Shi RZ et al. | Decreased anandamide transporter activity and calcitonin gene-related peptide production in spontaneously hypertensive rats: role of angiotensin II. | 2012 | Eur. J. Pharmacol. | pmid:22318155 |
| Rajesh M et al. | Cannabinoid 1 receptor promotes cardiac dysfunction, oxidative stress, inflammation, and fibrosis in diabetic cardiomyopathy. | 2012 | Diabetes | pmid:22315315 |
| Psychoyos D et al. | Cannabinoid receptor 1 signaling in embryo neurodevelopment. | 2012 | Birth Defects Res. B Dev. Reprod. Toxicol. | pmid:22311661 |
| Liu J et al. | Hepatic cannabinoid receptor-1 mediates diet-induced insulin resistance via inhibition of insulin signaling and clearance in mice. | 2012 | Gastroenterology | pmid:22307032 |
| Battista N et al. | The role of endocannabinoids in gonadal function and fertility along the evolutionary axis. | 2012 | Mol. Cell. Endocrinol. | pmid:22305972 |
| Izzo AA et al. | Inhibitory effect of cannabichromene, a major non-psychotropic cannabinoid extracted from Cannabis sativa, on inflammation-induced hypermotility in mice. | 2012 | Br. J. Pharmacol. | pmid:22300105 |
| Fowler CJ | Anandamide uptake explained? | 2012 | Trends Pharmacol. Sci. | pmid:22297258 |
| Sun Y et al. | Cannabinoid receptor activation disrupts the internal structure of hippocampal sharp wave-ripple complexes. | 2012 | J. Pharmacol. Sci. | pmid:22293299 |
| Alger BE | Endocannabinoids at the synapse a decade after the dies mirabilis (29 March 2001): what we still do not know. | 2012 | J. Physiol. (Lond.) | pmid:22289914 |
| Czikora à et al. | Vascular metabolism of anandamide to arachidonic acid affects myogenic constriction in response to intraluminal pressure elevation. | 2012 | Life Sci. | pmid:22285599 |
| Feuerecker M et al. | Effect of an acute consumption of a moderate amount of ethanol on plasma endocannabinoid levels in humans. | 2012 May-Jun | Alcohol Alcohol. | pmid:22278319 |
| Umathe SN et al. | Endocannabinoid analogues exacerbate marble-burying behavior in mice via TRPV1 receptor. | 2012 | Neuropharmacology | pmid:22248639 |
| Jarzimski C et al. | Changes of blood endocannabinoids during anaesthesia: a special case for fatty acid amide hydrolase inhibition by propofol? | 2012 | Br J Clin Pharmacol | pmid:22242687 |
| Harvey BS et al. | Contrasting protective effects of cannabinoids against oxidative stress and amyloid-β evoked neurotoxicity in vitro. | 2012 | Neurotoxicology | pmid:22233683 |
| Fowler CJ et al. | Inhibitory properties of ibuprofen and its amide analogues towards the hydrolysis and cyclooxygenation of the endocannabinoid anandamide. | 2013 | J Enzyme Inhib Med Chem | pmid:22225576 |
| Schulte K et al. | Cannabinoid CB1 receptor activation, pharmacological blockade, or genetic ablation affects the function of the muscarinic auto- and heteroreceptor. | 2012 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:22215206 |
| Battista N et al. | Abnormal anandamide metabolism in celiac disease. | 2012 | J. Nutr. Biochem. | pmid:22209002 |
| Marsicano G and Chaouloff F | Moving bliss: a new anandamide transporter. | 2012 | Nat. Neurosci. | pmid:22193249 |
| Jang Y et al. | Axonal neuropathy-associated TRPV4 regulates neurotrophic factor-derived axonal growth. | 2012 | J. Biol. Chem. | pmid:22187434 |
| Starowicz K et al. | Spinal anandamide produces analgesia in neuropathic rats: possible CB(1)- and TRPV1-mediated mechanisms. | 2012 | Neuropharmacology | pmid:22178705 |
| Wu X et al. | Alteration of endocannabinoid system in human gliomas. | 2012 | J. Neurochem. | pmid:22176552 |
| Li Q et al. | Effects of anandamide on potassium channels in rat ventricular myocytes: a suppression of I(to) and augmentation of K(ATP) channels. | 2012 | Am. J. Physiol., Cell Physiol. | pmid:22173869 |
| Wheal AJ et al. | Hydrogen peroxide as a mediator of vasorelaxation evoked by N-oleoylethanolamine and anandamide in rat small mesenteric arteries. | 2012 | Eur. J. Pharmacol. | pmid:22154756 |
| Cippitelli A et al. | Endocannabinoid regulation of acute and protracted nicotine withdrawal: effect of FAAH inhibition. | 2011 | PLoS ONE | pmid:22140525 |
| Reyes-Cabello C et al. | Effects of the anandamide uptake blocker AM404 on food intake depend on feeding status and route of administration. | 2012 | Pharmacol. Biochem. Behav. | pmid:22133635 |
| Taylor AH et al. | Modulation of the endocannabinoid system in viable and non-viable first trimester pregnancies by pregnancy-related hormones. | 2011 | Reprod. Biol. Endocrinol. | pmid:22126420 |
| Feuerecker M et al. | Effects of exercise stress on the endocannabinoid system in humans under field conditions. | 2012 | Eur. J. Appl. Physiol. | pmid:22101870 |
| Fu J et al. | A catalytically silent FAAH-1 variant drives anandamide transport in neurons. | 2012 | Nat. Neurosci. | pmid:22101642 |
| Hutchins-Wiese HL et al. | Hind limb suspension and long-chain omega-3 PUFA increase mRNA endocannabinoid system levels in skeletal muscle. | 2012 | J. Nutr. Biochem. | pmid:22051448 |
| Hamtiaux L et al. | Increasing antiproliferative properties of endocannabinoids in N1E-115 neuroblastoma cells through inhibition of their metabolism. | 2011 | PLoS ONE | pmid:22046372 |
| Brizzi A et al. | Resorcinol-sn-glycerol derivatives: novel 2-arachidonoylglycerol mimetics endowed with high affinity and selectivity for cannabinoid type 1 receptor. | 2011 | J. Med. Chem. | pmid:22044209 |
| Heyman E et al. | Intense exercise increases circulating endocannabinoid and BDNF levels in humans--possible implications for reward and depression. | 2012 | Psychoneuroendocrinology | pmid:22029953 |
| Ito T et al. | Propofol protects against anandamide-induced injury in human umbilical vein endothelial cells. | 2011 | Kurume Med J | pmid:22027193 |
| Malinowska B et al. | Triphasic blood pressure responses to cannabinoids: do we understand the mechanism? | 2012 | Br. J. Pharmacol. | pmid:22022923 |
| Haas MJ et al. | Inhibition of apolipoprotein A-I gene expression by obesity-associated endocannabinoids. | 2012 | Obesity (Silver Spring) | pmid:22016100 |
| Frazier CJ | Key questions of endocannabinoid signalling in the CNS: which, where and when? | 2011 | J. Physiol. (Lond.) | pmid:22001725 |
| Izumi Y and Zorumski CF | NMDA receptors, mGluR5, and endocannabinoids are involved in a cascade leading to hippocampal long-term depression. | 2012 | Neuropsychopharmacology | pmid:21993209 |
| Alenmyr L et al. | TRPV1 and TRPA1 stimulation induces MUC5B secretion in the human nasal airway in vivo. | 2011 | Clin Physiol Funct Imaging | pmid:21981454 |
| Thomas KC et al. | Contributions of TRPV1, endovanilloids, and endoplasmic reticulum stress in lung cell death in vitro and lung injury. | 2012 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:21949157 |
| Dean C | Cannabinoid and GABA modulation of sympathetic nerve activity and blood pressure in the dorsal periaqueductal gray of the rat. | 2011 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:21940402 |
| Butler RK et al. | Fear-induced suppression of nociceptive behaviour and activation of Akt signalling in the rat periaqueductal grey: role of fatty acid amide hydrolase. | 2012 | J. Psychopharmacol. (Oxford) | pmid:21926424 |
| Roy A et al. | Anandamide modulates carotid sinus nerve afferent activity via TRPV1 receptors increasing responses to heat. | 2012 | J. Appl. Physiol. | pmid:21903882 |
| Feledziak M et al. | SAR and LC/MS studies of β-lactamic inhibitors of human fatty acid amide hydrolase (hFAAH): evidence of a nonhydrolytic process. | 2011 | J. Med. Chem. | pmid:21899370 |
| Romero TR et al. | The neuronal NO synthase participation in the peripheral antinociception mechanism induced by several analgesic drugs. | 2011 | Nitric Oxide | pmid:21875681 |
| Ndong C et al. | Cloning and pharmacological characterization of the dog cannabinoid CBâ‚‚receptor. | 2011 | Eur. J. Pharmacol. | pmid:21871882 |
| Weller K et al. | TRPV1, TRPA1, and CB1 in the isolated vagus nerve--axonal chemosensitivity and control of neuropeptide release. | 2011 | Neuropeptides | pmid:21868092 |
| Dollery C | Investigative clinical pharmacology. | 2011 | Clin. Pharmacol. Ther. | pmid:21862965 |
| Clugston RD et al. | Altered hepatic lipid metabolism in C57BL/6 mice fed alcohol: a targeted lipidomic and gene expression study. | 2011 | J. Lipid Res. | pmid:21856784 |
| Mestre L et al. | Anandamide inhibits Theiler's virus induced VCAM-1 in brain endothelial cells and reduces leukocyte transmigration in a model of blood brain barrier by activation of CB(1) receptors. | 2011 | J Neuroinflammation | pmid:21851608 |
| Altinsoy A et al. | A cannabinoid ligand, anandamide, exacerbates endotoxin-induced uveitis in rabbits. | 2011 | J Ocul Pharmacol Ther | pmid:21848425 |
| Gatta-Cherifi B et al. | Simultaneous postprandial deregulation of the orexigenic endocannabinoid anandamide and the anorexigenic peptide YY in obesity. | 2012 | Int J Obes (Lond) | pmid:21844878 |
| Palermo G et al. | Covalent inhibitors of fatty acid amide hydrolase: a rationale for the activity of piperidine and piperazine aryl ureas. | 2011 | J. Med. Chem. | pmid:21830831 |
| Kim HY et al. | A synaptogenic amide N-docosahexaenoylethanolamide promotes hippocampal development. | 2011 | Prostaglandins Other Lipid Mediat. | pmid:21810478 |
| Yoshino H et al. | Postsynaptic diacylglycerol lipase mediates retrograde endocannabinoid suppression of inhibition in mouse prefrontal cortex. | 2011 | J. Physiol. (Lond.) | pmid:21807615 |
| Chianese R et al. | Anandamide modulates the expression of GnRH-II and GnRHRs in frog, Rana esculenta, diencephalon. | 2011 | Gen. Comp. Endocrinol. | pmid:21802420 |