Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Fowler CJ et al. | Inhibition of fatty acid amidohydrolase, the enzyme responsible for the metabolism of the endocannabinoid anandamide, by analogues of arachidonoyl-serotonin. | 2003 | J Enzyme Inhib Med Chem | pmid:14506913 |
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Vandevoorde S et al. | Esters, retroesters, and a retroamide of palmitic acid: pool for the first selective inhibitors of N-palmitoylethanolamine-selective acid amidase. | 2003 | J. Med. Chem. | pmid:14521402 |
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Marsicano G et al. | CB1 cannabinoid receptors and on-demand defense against excitotoxicity. | 2003 | Science | pmid:14526074 |
Gurney AM et al. | Two-pore domain K channel, TASK-1, in pulmonary artery smooth muscle cells. | 2003 | Circ. Res. | pmid:14551239 |
Maccarrone M et al. | Endocannabinoid degradation, endotoxic shock and inflammation. | 2002 | Curr Drug Targets Inflamm Allergy | pmid:14561206 |
Steffens M et al. | Quantitative measurement of depolarization-induced anandamide release in human and rat neocortex. | 2003 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:14566450 |
Han B et al. | Semiplenamides A-G, fatty acid amides from a Papua New Guinea collection of the marine cyanobacterium Lyngbya semiplena. | 2003 | J. Nat. Prod. | pmid:14575438 |
Chen N et al. | Inhibition by arachidonic acid and other fatty acids of dopamine uptake at the human dopamine transporter. | 2003 | Eur. J. Pharmacol. | pmid:14575792 |
Johnson RP et al. | System-specific O2 sensitivity of the tandem pore domain K+ channel TASK-1. | 2004 | Am. J. Physiol., Cell Physiol. | pmid:14576090 |
Biswas KK et al. | Membrane cholesterol but not putative receptors mediates anandamide-induced hepatocyte apoptosis. | 2003 | Hepatology | pmid:14578855 |
Egashira N et al. | Anandamide inhibits the DOI-induced head-twitch response in mice. | 2004 | Psychopharmacology (Berl.) | pmid:14586538 |
Gaetani S et al. | Anandamide hydrolysis: a new target for anti-anxiety drugs? | 2003 | Trends Mol Med | pmid:14604824 |
McAllister SD et al. | An aromatic microdomain at the cannabinoid CB(1) receptor constitutes an agonist/inverse agonist binding region. | 2003 | J. Med. Chem. | pmid:14613317 |
Seagard JL et al. | Anandamide content and interaction of endocannabinoid/GABA modulatory effects in the NTS on baroreflex-evoked sympathoinhibition. | 2004 | Am. J. Physiol. Heart Circ. Physiol. | pmid:14615281 |
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Kollarik M and Undem BJ | Activation of bronchopulmonary vagal afferent nerves with bradykinin, acid and vanilloid receptor agonists in wild-type and TRPV1-/- mice. | 2004 | J. Physiol. (Lond.) | pmid:14634201 |
Farquhar-Smith WP and Rice AS | A novel neuroimmune mechanism in cannabinoid-mediated attenuation of nerve growth factor-induced hyperalgesia. | 2003 | Anesthesiology | pmid:14639155 |
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Zoratti C et al. | Anandamide initiates Ca(2+) signaling via CB2 receptor linked to phospholipase C in calf pulmonary endothelial cells. | 2003 | Br. J. Pharmacol. | pmid:14645143 |
Wang H et al. | Differential G protein-coupled cannabinoid receptor signaling by anandamide directs blastocyst activation for implantation. | 2003 | Proc. Natl. Acad. Sci. U.S.A. | pmid:14645706 |
Nilsson O et al. | Cannabinoid CB1 receptor activation does not prevent the toxicity of glutamate towards embryonic chick telencephalon primary cultures. | 2003 | Comp. Biochem. Physiol. C Toxicol. Pharmacol. | pmid:14659458 |
Arizzi MN et al. | Behavioral effects of inhibition of cannabinoid metabolism: The amidase inhibitor AM374 enhances the suppression of lever pressing produced by exogenously administered anandamide. | 2004 | Life Sci. | pmid:14672756 |
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Wenger T et al. | The endogenous cannabinoid, anandamide, activates the hypothalamo-pituitary-adrenal axis in CB1 cannabinoid receptor knockout mice. | 2003 | Neuroendocrinology | pmid:14688442 |
Kasai HF et al. | Analyses of anandamide and endocannabinoid-like compounds using collision-induced dissociation in fast atom bombardment ionization-mass spectrometry and gas chromatography/chemical ionization-mass spectrometry. | 2003 | Anal Sci | pmid:14696920 |