Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kaplan BL et al. | Inhibition of leukocyte function and interleukin-2 gene expression by 2-methylarachidonyl-(2'-fluoroethyl)amide, a stable congener of the endogenous cannabinoid receptor ligand anandamide. | 2005 | Toxicol. Appl. Pharmacol. | pmid:15893538 |
Kondakala S et al. | Effects of acute exposure to chlorpyrifos on cholinergic and non-cholinergic targets in normal and high-fat fed male C57BL/6J mice. | 2017 | Toxicol. Appl. Pharmacol. | pmid:29097212 |
Kodani SD et al. | Parabens inhibit fatty acid amide hydrolase: A potential role in paraben-enhanced 3T3-L1 adipocyte differentiation. | 2016 | Toxicol. Lett. | pmid:27659731 |
Carr RL et al. | Effect of developmental chlorpyrifos exposure, on endocannabinoid metabolizing enzymes, in the brain of juvenile rats. | 2011 | Toxicol. Sci. | pmid:21507991 |
Carr RL et al. | Induction of endocannabinoid levels in juvenile rat brain following developmental chlorpyrifos exposure. | 2013 | Toxicol. Sci. | pmid:23761300 |
Hsu SS et al. | Anandamide-induced Ca2+ elevation leading to p38 MAPK phosphorylation and subsequent cell death via apoptosis in human osteosarcoma cells. | 2007 | Toxicology | pmid:17222495 |
Bluett RJ et al. | Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation. | 2014 | Transl Psychiatry | pmid:25004388 |
Leweke FM et al. | Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia. | 2012 | Transl Psychiatry | pmid:22832859 |
Maccarrone M et al. | Intracellular trafficking of anandamide: new concepts for signaling. | 2010 | Trends Biochem. Sci. | pmid:20570522 |
Alhouayek M and Muccioli GG | The endocannabinoid system in inflammatory bowel diseases: from pathophysiology to therapeutic opportunity. | 2012 | Trends Mol Med | pmid:22917662 |