Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Vinod KY et al. | Dysfunction in fatty acid amide hydrolase is associated with depressive-like behavior in Wistar Kyoto rats. | 2012 | PLoS ONE | pmid:22606285 |
Woolcott OO et al. | High-fat diet-induced insulin resistance does not increase plasma anandamide levels or potentiate anandamide insulinotropic effect in isolated canine islets. | 2015 | PLoS ONE | pmid:25855974 |
Nicholson J et al. | Leptin levels are negatively correlated with 2-arachidonoylglycerol in the cerebrospinal fluid of patients with osteoarthritis. | 2015 | PLoS ONE | pmid:25835291 |
Björklund E et al. | Involvement of fatty acid amide hydrolase and fatty acid binding protein 5 in the uptake of anandamide by cell lines with different levels of fatty acid amide hydrolase expression: a pharmacological study. | 2014 | PLoS ONE | pmid:25078278 |
Dong W et al. | Simulation of Swanson's literature-based discovery: anandamide treatment inhibits growth of gastric cancer cells in vitro and in silico. | 2014 | PLoS ONE | pmid:24949851 |
Li Q et al. | Anandamide reduces intracellular Ca2+ concentration through suppression of Na+/Ca2+ exchanger current in rat cardiac myocytes. | 2013 | PLoS ONE | pmid:23667607 |
Lobato NS et al. | Reduced endothelium-dependent relaxation to anandamide in mesenteric arteries from young obese Zucker rats. | 2013 | PLoS ONE | pmid:23667622 |
Gatta L et al. | Discovery of prostamide F2α and its role in inflammatory pain and dorsal horn nociceptive neuron hyperexcitability. | 2012 | PLoS ONE | pmid:22363560 |
Sordelli MS et al. | The effect of anandamide on uterine nitric oxide synthase activity depends on the presence of the blastocyst. | 2011 | PLoS ONE | pmid:21559512 |
Derbenev AV and Smith BN | Dexamethasone rapidly increases GABA release in the dorsal motor nucleus of the vagus via retrograde messenger-mediated enhancement of TRPV1 activity. | 2013 | PLoS ONE | pmid:23936221 |
Osycka-Salut C et al. | Anandamide induces sperm release from oviductal epithelia through nitric oxide pathway in bovines. | 2012 | PLoS ONE | pmid:22363468 |
Gervasi MG et al. | Anandamide capacitates bull spermatozoa through CB1 and TRPV1 activation. | 2011 | PLoS ONE | pmid:21347292 |
Björklund E et al. | Ketoconazole inhibits the cellular uptake of anandamide via inhibition of FAAH at pharmacologically relevant concentrations. | 2014 | PLoS ONE | pmid:24466356 |
Kwolek G et al. | [Influence of anandamide, the endogenous agonist of cannabinoid receptors on the circulatory system]. | 2005 | Postepy Hig Med Dosw (Online) | pmid:15928605 |
Pertwee RG | Elevating endocannabinoid levels: pharmacological strategies and potential therapeutic applications. | 2014 | Proc Nutr Soc | pmid:24135210 |
Burston JJ and Woodhams SG | Endocannabinoid system and pain: an introduction. | 2014 | Proc Nutr Soc | pmid:24148358 |
Piomelli D et al. | Structural determinants for recognition and translocation by the anandamide transporter. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10318965 |
Scorticati C et al. | The inhibitory effect of anandamide on luteinizing hormone-releasing hormone secretion is reversed by estrogen. | 2004 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15280536 |
Boger DL et al. | Exceptionally potent inhibitors of fatty acid amide hydrolase: the enzyme responsible for degradation of endogenous oleamide and anandamide. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10805767 |
De Petrocellis L et al. | The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9653194 |