Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Somatosensory Disorders D020886 1 associated lipids
Orthostatic Intolerance D054971 1 associated lipids
Sleep Disorders, Intrinsic D020919 1 associated lipids
Headache Disorders, Secondary D051271 1 associated lipids
Vascular System Injuries D057772 2 associated lipids
Amnesia, Anterograde D020324 2 associated lipids
Substance-Related Disorders D019966 2 associated lipids
Ocular Hypotension D015814 2 associated lipids
Cardiovirus Infections D018188 3 associated lipids
Schistosomiasis japonica D012554 3 associated lipids
Bulimia D002032 3 associated lipids
Acute Pain D059787 3 associated lipids
Urinary Bladder Diseases D001745 4 associated lipids
Urinary Incontinence D014549 4 associated lipids
Picornaviridae Infections D010850 4 associated lipids
Fibromyalgia D005356 4 associated lipids
Impotence, Vasculogenic D018783 4 associated lipids
Intestinal Pseudo-Obstruction D007418 5 associated lipids
Pregnancy, Ectopic D011271 5 associated lipids
Muscle Spasticity D009128 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Authors Title Published Journal PubMed Link
Bojesen IN and Hansen HS Membrane transport of anandamide through resealed human red blood cell membranes. 2005 J. Lipid Res. pmid:15930521
Fowler CJ et al. The endocannabinoid signaling system: pharmacological and therapeutic aspects. 2005 Pharmacol. Biochem. Behav. pmid:15935456
Zhang N et al. A proinflammatory chemokine, CCL3, sensitizes the heat- and capsaicin-gated ion channel TRPV1. 2005 Proc. Natl. Acad. Sci. U.S.A. pmid:15764707
Mechoulam R The promise of advances in the field of endocannabinoids. 2004 Feb-Apr Neuro Endocrinol. Lett. pmid:15159675
Fride E The endocannabinoid-CB receptor system: Importance for development and in pediatric disease. 2004 Feb-Apr Neuro Endocrinol. Lett. pmid:15159678
Russo EB Clinical endocannabinoid deficiency (CECD): can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions? 2004 Feb-Apr Neuro Endocrinol. Lett. pmid:15159679
Rodríguez de Fonseca F [The endocannabinoid system and food intake control]. 2004 Apr-Jun Rev Med Univ Navarra pmid:15382609
Chen P et al. Metabolism of anandamide in cerebral microvascular endothelial cells. 2004 Prostaglandins Other Lipid Mediat. pmid:15165032
Breivogel CS et al. Cannabinoid signaling in rat cerebellar granule cells: G-protein activation, inhibition of glutamate release and endogenous cannabinoids. 2004 Neuropharmacology pmid:15165836
Kim J and Alger BE Inhibition of cyclooxygenase-2 potentiates retrograde endocannabinoid effects in hippocampus. 2004 Nat. Neurosci. pmid:15184902
Witting A et al. Endocannabinoids accumulate in spinal cord of SOD1 G93A transgenic mice. 2004 J. Neurochem. pmid:15189359
Peroni RN et al. Sex-linked differences in the vasorelaxant effects of anandamide in vascular mesenteric beds: role of oestrogens. 2004 Eur. J. Pharmacol. pmid:15189776
Seagard JL et al. Anandamide content and interaction of endocannabinoid/GABA modulatory effects in the NTS on baroreflex-evoked sympathoinhibition. 2004 Am. J. Physiol. Heart Circ. Physiol. pmid:14615281
Johnson RP et al. System-specific O2 sensitivity of the tandem pore domain K+ channel TASK-1. 2004 Am. J. Physiol., Cell Physiol. pmid:14576090
Okamoto Y et al. Molecular characterization of a phospholipase D generating anandamide and its congeners. 2004 J. Biol. Chem. pmid:14634025
Kollarik M and Undem BJ Activation of bronchopulmonary vagal afferent nerves with bradykinin, acid and vanilloid receptor agonists in wild-type and TRPV1-/- mice. 2004 J. Physiol. (Lond.) pmid:14634201
Price TJ et al. Modulation of trigeminal sensory neuron activity by the dual cannabinoid-vanilloid agonists anandamide, N-arachidonoyl-dopamine and arachidonyl-2-chloroethylamide. 2004 Br. J. Pharmacol. pmid:15006899
Egashira N et al. Anandamide inhibits the DOI-induced head-twitch response in mice. 2004 Psychopharmacology (Berl.) pmid:14586538
McFarland MJ et al. A role for caveolae/lipid rafts in the uptake and recycling of the endogenous cannabinoid anandamide. 2004 J. Biol. Chem. pmid:15292270
Lazzarin N et al. Fluctuations of fatty acid amide hydrolase and anandamide levels during the human ovulatory cycle. 2004 Gynecol. Endocrinol. pmid:15293893
Do Y et al. Activation through cannabinoid receptors 1 and 2 on dendritic cells triggers NF-kappaB-dependent apoptosis: novel role for endogenous and exogenous cannabinoids in immunoregulation. 2004 J. Immunol. pmid:15294950
Blázquez C et al. Cannabinoids inhibit the vascular endothelial growth factor pathway in gliomas. 2004 Cancer Res. pmid:15313899
Oka S et al. 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, induces the migration of EoL-1 human eosinophilic leukemia cells and human peripheral blood eosinophils. 2004 J. Leukoc. Biol. pmid:15316028
Wiley JL et al. A comparison of the discriminative stimulus effects of delta(9)-tetrahydrocannabinol and O-1812, a potent and metabolically stable anandamide analog, in rats. 2004 Exp Clin Psychopharmacol pmid:15301634
McAllister SD et al. Structural mimicry in class A G protein-coupled receptor rotamer toggle switches: the importance of the F3.36(201)/W6.48(357) interaction in cannabinoid CB1 receptor activation. 2004 J. Biol. Chem. pmid:15326174
Di Marzo V et al. The anandamide membrane transporter. Structure-activity relationships of anandamide and oleoylethanolamine analogs with phenyl rings in the polar head group region. 2004 Bioorg. Med. Chem. pmid:15351399
Scorticati C et al. The inhibitory effect of anandamide on luteinizing hormone-releasing hormone secretion is reversed by estrogen. 2004 Proc. Natl. Acad. Sci. U.S.A. pmid:15280536
Rockwell CE and Kaminski NE A cyclooxygenase metabolite of anandamide causes inhibition of interleukin-2 secretion in murine splenocytes. 2004 J. Pharmacol. Exp. Ther. pmid:15284281
Yue HY et al. AM404 enhances the spontaneous release of L-glutamate in a manner sensitive to capsazepine in adult rat substantia gelatinosa neurones. 2004 Brain Res. pmid:15276889
Akerman S et al. Anandamide acts as a vasodilator of dural blood vessels in vivo by activating TRPV1 receptors. 2004 Br. J. Pharmacol. pmid:15277315
Ortega-Gutiérrez S et al. Comparison of anandamide transport in FAAH wild-type and knockout neurons: evidence for contributions by both FAAH and the CB1 receptor to anandamide uptake. 2004 Biochemistry pmid:15209515
D'Amico M et al. Inhibition by anandamide and synthetic cannabimimetics of the release of [3H]D-aspartate and [3H]GABA from synaptosomes isolated from the rat hippocampus. 2004 Neurochem. Res. pmid:15260134
Boldrup L et al. A simple stopped assay for fatty acid amide hydrolase avoiding the use of a chloroform extraction phase. 2004 J. Biochem. Biophys. Methods pmid:15262451
Lichtman AH et al. Reversible inhibitors of fatty acid amide hydrolase that promote analgesia: evidence for an unprecedented combination of potency and selectivity. 2004 J. Pharmacol. Exp. Ther. pmid:15229230
Barros DM et al. Interactions between anandamide-induced anterograde amnesia and post-training memory modulatory systems. 2004 Brain Res. pmid:15234253
Li J et al. Muscle pressor reflex: potential role of vanilloid type 1 receptor and acid-sensing ion channel. 2004 J. Appl. Physiol. pmid:15220301
Alger BE Endocannabinoids: getting the message across. 2004 Proc. Natl. Acad. Sci. U.S.A. pmid:15173576
Koura Y et al. Anandamide decreases glomerular filtration rate through predominant vasodilation of efferent arterioles in rat kidneys. 2004 J. Am. Soc. Nephrol. pmid:15153559
Lichtman AH et al. Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia. 2004 Pain pmid:15157693
Mendiguren A and Pineda J Cannabinoids enhance N-methyl-D-aspartate-induced excitation of locus coeruleus neurons by CB1 receptors in rat brain slices. 2004 Neurosci. Lett. pmid:15157983
Karlsson M et al. Reversible, temperature-dependent, and AM404-inhibitable adsorption of anandamide to cell culture wells as a confounding factor in release experiments. 2004 Eur J Pharm Sci pmid:15158903
González S et al. Behavioral and molecular changes elicited by acute administration of SR141716 to Delta9-tetrahydrocannabinol-tolerant rats: an experimental model of cannabinoid abstinence. 2004 Drug Alcohol Depend pmid:15099659
Parkkari T et al. Synthesis and CB1 receptor activities of novel arachidonyl alcohol derivatives. 2004 Bioorg. Med. Chem. Lett. pmid:15149681
Pacher P et al. Haemodynamic profile and responsiveness to anandamide of TRPV1 receptor knock-out mice. 2004 J. Physiol. (Lond.) pmid:15121805
Van Der Stelt M and Di Marzo V Endovanilloids. Putative endogenous ligands of transient receptor potential vanilloid 1 channels. 2004 Eur. J. Biochem. pmid:15128293
Randall MD et al. The complexities of the cardiovascular actions of cannabinoids. 2004 Br. J. Pharmacol. pmid:15131000
Fegley D et al. Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM1172. 2004 Proc. Natl. Acad. Sci. U.S.A. pmid:15138300
Fernandez-Espejo E and Galan-Rodriguez B Sensorimotor gating in mice is disrupted after AM404, an anandamide reuptake and degradation inhibitor. 2004 Psychopharmacology (Berl.) pmid:15088080
Valenti M et al. Differential diurnal variations of anandamide and 2-arachidonoyl-glycerol levels in rat brain. 2004 Cell. Mol. Life Sci. pmid:15095014
Kishimoto S et al. 2-Arachidonoylglycerol, an endogenous cannabinoid receptor ligand, induces accelerated production of chemokines in HL-60 cells. 2004 J. Biochem. pmid:15115777
Gardener MJ et al. Functional evidence of a role for two-pore domain potassium channels in rat mesenteric and pulmonary arteries. 2004 Br. J. Pharmacol. pmid:15066906
Weber A et al. Formation of prostamides from anandamide in FAAH knockout mice analyzed by HPLC with tandem mass spectrometry. 2004 J. Lipid Res. pmid:14729864
Kraft B et al. Cannabinoid receptor-independent suppression of the superoxide generation of human neutrophils (PMN) by CP55 940, but not by anandamide. 2004 Life Sci. pmid:15193957
de Lago E et al. In vivo pharmacological actions of two novel inhibitors of anandamide cellular uptake. 2004 Eur. J. Pharmacol. pmid:14744610
Dennedy MC et al. Cannabinoids and the human uterus during pregnancy. 2004 Am. J. Obstet. Gynecol. pmid:14749627
Moezi L et al. Potentiation of anandamide effects in mesenteric beds isolated from bile duct-ligated rats: role of nitric oxide. 2004 Eur. J. Pharmacol. pmid:14751408
Piomelli D THC: moderation during implantation. 2004 Nat. Med. pmid:14702623
Arizzi MN et al. Behavioral effects of inhibition of cannabinoid metabolism: The amidase inhibitor AM374 enhances the suppression of lever pressing produced by exogenously administered anandamide. 2004 Life Sci. pmid:14672756
Martínez-González D et al. Oleamide and anandamide effects on food intake and sexual behavior of rats. 2004 Neurosci. Lett. pmid:15193744
Matias I et al. Prostaglandin ethanolamides (prostamides): in vitro pharmacology and metabolism. 2004 J. Pharmacol. Exp. Ther. pmid:14757851
Lin GC et al. Gap junctional communication modulates agonist-induced calcium oscillations in transfected HeLa cells. 2004 J. Cell. Sci. pmid:14762115
Lees G and Dougalis A Differential effects of the sleep-inducing lipid oleamide and cannabinoids on the induction of long-term potentiation in the CA1 neurons of the rat hippocampus in vitro. 2004 Brain Res. pmid:14715144
Ruiz-Llorente L et al. Characterization of an anandamide degradation system in prostate epithelial PC-3 cells: synthesis of new transporter inhibitors as tools for this study. 2004 Br. J. Pharmacol. pmid:14718261
Huitron-Resendiz S et al. Characterization of the sleep-wake patterns in mice lacking fatty acid amide hydrolase. 2004 Sleep pmid:15453543
Akerman S et al. Anandamide is able to inhibit trigeminal neurons using an in vivo model of trigeminovascular-mediated nociception. 2004 J. Pharmacol. Exp. Ther. pmid:14718591
Maccarrone M Inhibition of anandamide hydrolysis: cells also know how to do it. 2004 Trends Mol Med pmid:14720580
Bátkai S et al. Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension. 2004 Circulation pmid:15451779
Contassot E et al. Arachidonylethanolamide induces apoptosis of human glioma cells through vanilloid receptor-1. 2004 J. Neuropathol. Exp. Neurol. pmid:15453094
Storr M et al. Cannabinoid receptor type 1 modulates excitatory and inhibitory neurotransmission in mouse colon. 2004 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:12893627
Golech SA et al. Human brain endothelium: coexpression and function of vanilloid and endocannabinoid receptors. 2004 Brain Res. Mol. Brain Res. pmid:15548432
Battista N et al. Endocannabinoids and their involvement in the neurovascular system. 2004 Curr Neurovasc Res pmid:16185189
Mukherjee S et al. Species comparison and pharmacological characterization of rat and human CB2 cannabinoid receptors. 2004 Eur. J. Pharmacol. pmid:15556131
López-Miranda V et al. Anandamide vehicles: a comparative study. 2004 Eur. J. Pharmacol. pmid:15556148
Braun M and Kietzmann M Ischaemia-reperfusion injury in the isolated haemoperfused bovine uterus: an in vitro model of acute inflammation. 2004 Altern Lab Anim pmid:15601235
Dinis P et al. Anandamide-evoked activation of vanilloid receptor 1 contributes to the development of bladder hyperreflexia and nociceptive transmission to spinal dorsal horn neurons in cystitis. 2004 J. Neurosci. pmid:15601931
Costanzi M et al. Effects of anandamide and morphine combinations on memory consolidation in cd1 mice: involvement of dopaminergic mechanisms. 2004 Neurobiol Learn Mem pmid:14990234
Steffens M et al. Cannabinoid CB1 receptor-mediated modulation of evoked dopamine release and of adenylyl cyclase activity in the human neocortex. 2004 Br. J. Pharmacol. pmid:14993102
Sun YX et al. Biosynthesis of anandamide and N-palmitoylethanolamine by sequential actions of phospholipase A2 and lysophospholipase D. 2004 Biochem. J. pmid:14998370
Berger C et al. Massive accumulation of N-acylethanolamines after stroke. Cell signalling in acute cerebral ischemia? 2004 J. Neurochem. pmid:15009671
Fernandez-Espejo E et al. Experimental parkinsonism alters anandamide precursor synthesis, and functional deficits are improved by AM404: a modulator of endocannabinoid function. 2004 Neuropsychopharmacology pmid:15010694
Cruz F Mechanisms involved in new therapies for overactive bladder. 2004 Urology pmid:15013655
Joseph J et al. Anandamide is an endogenous inhibitor for the migration of tumor cells and T lymphocytes. 2004 Cancer Immunol. Immunother. pmid:15034673
Ligresti A et al. Further evidence for the existence of a specific process for the membrane transport of anandamide. 2004 Biochem. J. pmid:14969584
Guo J and Ikeda SR Endocannabinoids modulate N-type calcium channels and G-protein-coupled inwardly rectifying potassium channels via CB1 cannabinoid receptors heterologously expressed in mammalian neurons. 2004 Mol. Pharmacol. pmid:14978245
Basta PV et al. Preparation of monoclonal antibodies reactive to the endogenous small molecule, anandamide. 2004 J. Immunol. Methods pmid:14980433
Fernández-Solari J et al. Alcohol inhibits luteinizing hormone-releasing hormone release by activating the endocannabinoid system. 2004 Proc. Natl. Acad. Sci. U.S.A. pmid:14981261
Evans RM et al. Multiple actions of anandamide on neonatal rat cultured sensory neurones. 2004 Br. J. Pharmacol. pmid:15023857
Szendrei K [A novel analgesics made from Cannabis]. 2004 Ideggyogy Sz pmid:15042867
Contassot E et al. Arachidonyl ethanolamide induces apoptosis of uterine cervix cancer cells via aberrantly expressed vanilloid receptor-1. 2004 Gynecol. Oncol. pmid:15047233
Piomelli D The endogenous cannabinoid system and the treatment of marijuana dependence. 2004 Neuropharmacology pmid:15464150
Fernández-Rodriguez CM et al. Circulating endogenous cannabinoid anandamide and portal, systemic and renal hemodynamics in cirrhosis. 2004 Liver Int. pmid:15482346
Triggle CR et al. The endothelium in health and disease: a discussion of the contribution of non-nitric oxide endothelium-derived vasoactive mediators to vascular homeostasis in normal vessels and in type II diabetes. 2004 Mol. Cell. Biochem. pmid:15524164
Holt S et al. Lipopolysaccharide-induced pulmonary inflammation is not accompanied by a release of anandamide into the lavage fluid or a down-regulation of the activity of fatty acid amide hydrolase. 2004 Life Sci. pmid:15530507
Habayeb OM et al. Plasma levels of the endocannabinoid anandamide in women--a potential role in pregnancy maintenance and labor? 2004 J. Clin. Endocrinol. Metab. pmid:15531501
Muthian S et al. Anandamide content is increased and CB1 cannabinoid receptor blockade is protective during transient, focal cerebral ischemia. 2004 Neuroscience pmid:15541895
McFarland MJ and Barker EL Anandamide transport. 2004 Pharmacol. Ther. pmid:15518883
Ghafouri N et al. Inhibition of monoacylglycerol lipase and fatty acid amide hydrolase by analogues of 2-arachidonoylglycerol. 2004 Br. J. Pharmacol. pmid:15492019
Lanzafame AA et al. Effects of anandamide on the binding and signaling properties of M1 muscarinic acetylcholine receptors. 2004 Biochem. Pharmacol. pmid:15498511
Motobe T et al. Endogenous cannabinoids are candidates for lipid mediators of bone cement implantation syndrome. 2004 Shock pmid:14676677
De Petrocellis L et al. Actions of two naturally occurring saturated N-acyldopamines on transient receptor potential vanilloid 1 (TRPV1) channels. 2004 Br. J. Pharmacol. pmid:15289293