Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

Cross Reference

Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Headache Disorders, Secondary D051271 1 associated lipids
Somatosensory Disorders D020886 1 associated lipids
Orthostatic Intolerance D054971 1 associated lipids
Sleep Disorders, Intrinsic D020919 1 associated lipids
Vascular System Injuries D057772 2 associated lipids
Amnesia, Anterograde D020324 2 associated lipids
Substance-Related Disorders D019966 2 associated lipids
Ocular Hypotension D015814 2 associated lipids
Bulimia D002032 3 associated lipids
Acute Pain D059787 3 associated lipids
Cardiovirus Infections D018188 3 associated lipids
Schistosomiasis japonica D012554 3 associated lipids
Impotence, Vasculogenic D018783 4 associated lipids
Urinary Incontinence D014549 4 associated lipids
Picornaviridae Infections D010850 4 associated lipids
Fibromyalgia D005356 4 associated lipids
Urinary Bladder Diseases D001745 4 associated lipids
Sleep Deprivation D012892 5 associated lipids
Muscle Spasticity D009128 5 associated lipids
Brain Concussion D001924 5 associated lipids
Per page 10 20 50 100 | Total 105

PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

Download all related citations
Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Chen N et al. Inhibition by arachidonic acid and other fatty acids of dopamine uptake at the human dopamine transporter. 2003 Eur. J. Pharmacol. pmid:14575792
Campanucci VA et al. A novel O2-sensing mechanism in rat glossopharyngeal neurones mediated by a halothane-inhibitable background K+ conductance. 2003 J. Physiol. (Lond.) pmid:12640017
Sarker KP et al. ASK1-p38 MAPK/JNK signaling cascade mediates anandamide-induced PC12 cell death. 2003 J. Neurochem. pmid:12641726
Holt S and Fowler CJ Anandamide metabolism by fatty acid amide hydrolase in intact C6 glioma cells. Increased sensitivity to inhibition by ibuprofen and flurbiprofen upon reduction of extra- but not intracellular pH. 2003 Naunyn Schmiedebergs Arch. Pharmacol. pmid:12644895
Juntunen J et al. Anandamide prodrugs. 1. Water-soluble phosphate esters of arachidonylethanolamide and R-methanandamide. 2003 Eur J Pharm Sci pmid:12729860
Basavarajappa BS et al. Chronic ethanol inhibits the anandamide transport and increases extracellular anandamide levels in cerebellar granule neurons. 2003 Eur. J. Pharmacol. pmid:12679143
Ortar G et al. Novel selective and metabolically stable inhibitors of anandamide cellular uptake. 2003 Biochem. Pharmacol. pmid:12732359
Clement AB et al. Increased seizure susceptibility and proconvulsant activity of anandamide in mice lacking fatty acid amide hydrolase. 2003 J. Neurosci. pmid:12736361
Hermann H et al. Dual effect of cannabinoid CB1 receptor stimulation on a vanilloid VR1 receptor-mediated response. 2003 Cell. Mol. Life Sci. pmid:12737320
Maccarrone M and Finazzi-Agró A The endocannabinoid system, anandamide and the regulation of mammalian cell apoptosis. 2003 Cell Death Differ. pmid:12934069
Lo YK et al. Effect of arvanil (N-arachidonoyl-vanillyl-amine), a nonpungent anandamide-capsaicin hybrid, on ion currents in NG108-15 neuronal cells. 2003 Biochem. Pharmacol. pmid:12566085
Vandevoorde S et al. Modifications of the ethanolamine head in N-palmitoylethanolamine: synthesis and evaluation of new agents interfering with the metabolism of anandamide. 2003 J. Med. Chem. pmid:12672243
van der Stelt M et al. Acute neuronal injury, excitotoxicity, and the endocannabinoid system. 2002 Oct-Dec Mol. Neurobiol. pmid:12428763
Mechoulam R Discovery of endocannabinoids and some random thoughts on their possible roles in neuroprotection and aggression. 2002 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:12052029
Sugiura T et al. Biosynthesis and degradation of anandamide and 2-arachidonoylglycerol and their possible physiological significance. 2002 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:12052034
Fowler CJ and Jacobsson SO Cellular transport of anandamide, 2-arachidonoylglycerol and palmitoylethanolamide--targets for drug development? 2002 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:12052035
Deutsch DG et al. The fatty acid amide hydrolase (FAAH). 2002 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:12052036
Fride E Endocannabinoids in the central nervous system--an overview. 2002 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:12052038
Pinto L et al. Endocannabinoids and the gut. 2002 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:12052047
Högestätt ED and Zygmunt PM Cardiovascular pharmacology of anandamide. 2002 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:12052048
Di Marzo V et al. Anandamide receptors. 2002 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:12052051
Porter AC et al. Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor. 2002 J. Pharmacol. Exp. Ther. pmid:12023533
Kreitzer AC and Regehr WG Retrograde signaling by endocannabinoids. 2002 Curr. Opin. Neurobiol. pmid:12049940
Maccarrone M et al. Endocannabinoid degradation, endotoxic shock and inflammation. 2002 Curr Drug Targets Inflamm Allergy pmid:14561206
Wallace MJ et al. Evidence for a physiological role of endocannabinoids in the modulation of seizure threshold and severity. 2002 Eur. J. Pharmacol. pmid:12359270
Roberts LA et al. Anandamide is a partial agonist at native vanilloid receptors in acutely isolated mouse trigeminal sensory neurons. 2002 Br. J. Pharmacol. pmid:12359623
Darmani NA The potent emetogenic effects of the endocannabinoid, 2-AG (2-arachidonoylglycerol) are blocked by delta(9)-tetrahydrocannabinol and other cannnabinoids. 2002 J. Pharmacol. Exp. Ther. pmid:11752094
Mukhopadhyay S et al. Anandamide-induced vasorelaxation in rabbit aortic rings has two components: G protein dependent and independent. 2002 Am. J. Physiol. Heart Circ. Physiol. pmid:12003810
Bisogno T et al. Fatty acid amide hydrolase, an enzyme with many bioactive substrates. Possible therapeutic implications. 2002 Curr. Pharm. Des. pmid:11945157
Kozak KR et al. Metabolism of the endocannabinoids, 2-arachidonylglycerol and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters and ethanolamides. 2002 J. Biol. Chem. pmid:12244105
Burstein SH et al. Regulation of anandamide tissue levels by N-arachidonylglycine. 2002 Biochem. Pharmacol. pmid:12234618
Luo C et al. Anandamide inhibits excitatory transmission to rat substantia gelatinosa neurones in a manner different from that of capsaicin. 2002 Neurosci. Lett. pmid:11872246
Wenger T et al. The hypothalamic levels of the endocannabinoid, anandamide, peak immediately before the onset of puberty in female rats. 2002 Life Sci. pmid:11883716
Molina-Holgado F et al. Role of CB1 and CB2 receptors in the inhibitory effects of cannabinoids on lipopolysaccharide-induced nitric oxide release in astrocyte cultures. 2002 J. Neurosci. Res. pmid:11891798
Ford WR et al. Evidence of a novel site mediating anandamide-induced negative inotropic and coronary vasodilatator responses in rat isolated hearts. 2002 Br. J. Pharmacol. pmid:11877326
Harris D et al. Characterization of vasorelaxant responses to anandamide in the rat mesenteric arterial bed. 2002 J. Physiol. (Lond.) pmid:11897858
Lin YS and Lee LY Stimulation of pulmonary vagal C-fibres by anandamide in anaesthetized rats: role of vanilloid type 1 receptors. 2002 J. Physiol. (Lond.) pmid:11897863
van der Stelt M et al. Oxygenated metabolites of anandamide and 2-arachidonoylglycerol: conformational analysis and interaction with cannabinoid receptors, membrane transporter, and fatty acid amide hydrolase. 2002 J. Med. Chem. pmid:12166944
Someya A et al. Arachidonic acid release and prostaglandin F(2alpha) formation induced by anandamide and capsaicin in PC12 cells. 2002 Eur. J. Pharmacol. pmid:12206851
Di Marzo V et al. A structure/activity relationship study on arvanil, an endocannabinoid and vanilloid hybrid. 2002 J. Pharmacol. Exp. Ther. pmid:11861807
Barnett-Norris J et al. Conformational memories and the endocannabinoid binding site at the cannabinoid CB1 receptor. 2002 J. Med. Chem. pmid:12166938
Habayeb OM et al. Endogenous cannabinoids: metabolism and their role in reproduction. 2002 Life Sci. pmid:12148689
Szallasi A Vanilloid (capsaicin) receptors in health and disease. 2002 Am. J. Clin. Pathol. pmid:12109845
Dinh TP et al. Brain monoglyceride lipase participating in endocannabinoid inactivation. 2002 Proc. Natl. Acad. Sci. U.S.A. pmid:12136125
Liu WM et al. Effects of anandamide on embryo implantation in the mouse. 2002 Life Sci. pmid:12137909
Di Marzo V et al. Endovanilloid signaling in pain. 2002 Curr. Opin. Neurobiol. pmid:12139983
Matias I et al. Presence and regulation of the endocannabinoid system in human dendritic cells. 2002 Eur. J. Biochem. pmid:12153574
Schäbitz WR et al. Release of fatty acid amides in a patient with hemispheric stroke: a microdialysis study. 2002 Stroke pmid:12154273
Chemin J et al. Neuronal T-type alpha 1H calcium channels induce neuritogenesis and expression of high-voltage-activated calcium channels in the NG108-15 cell line. 2002 J. Neurosci. pmid:12177183
Gubellini P et al. Experimental parkinsonism alters endocannabinoid degradation: implications for striatal glutamatergic transmission. 2002 J. Neurosci. pmid:12177188