Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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pmid:24114173 | ||||
pmid:24117326 | ||||
Bernabò N et al. | Systems biology analysis of the endocannabinoid system reveals a scale-free network with distinct roles for anandamide and 2-arachidonoylglycerol. | 2013 | OMICS | pmid:24117401 |
Marichal-Cancino BA et al. | Role of pre-junctional CB1, but not CB2 , TRPV1 or GPR55 receptors in anandamide-induced inhibition of the vasodepressor sensory CGRPergic outflow in pithed rats. | 2014 | Basic Clin. Pharmacol. Toxicol. | pmid:24118786 |
Stanley CP et al. | Cannabinoids alter endothelial function in the Zucker rat model of type 2 diabetes. | 2013 | Eur. J. Pharmacol. | pmid:24120371 |
Pertwee RG | Elevating endocannabinoid levels: pharmacological strategies and potential therapeutic applications. | 2014 | Proc Nutr Soc | pmid:24135210 |
Burston JJ and Woodhams SG | Endocannabinoid system and pain: an introduction. | 2014 | Proc Nutr Soc | pmid:24148358 |
Desroches J et al. | Endocannabinoids decrease neuropathic pain-related behavior in mice through the activation of one or both peripheral CBâ‚ and CBâ‚‚ receptors. | 2014 | Neuropharmacology | pmid:24148808 |
Wenzel D et al. | Endocannabinoid anandamide mediates hypoxic pulmonary vasoconstriction. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24167249 |
Liu J et al. | Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24191036 |
Battista N et al. | Analytical approaches for the determination of phytocannabinoids and endocannabinoids in human matrices. | 2014 Jan-Feb | Drug Test Anal | pmid:24218186 |
Leung K et al. | Role of FAAH-like anandamide transporter in anandamide inactivation. | 2013 | PLoS ONE | pmid:24223930 |
Harvey BS et al. | Interleukin 17A evoked mucosal damage is attenuated by cannabidiol and anandamide in a human colonic explant model. | 2014 | Cytokine | pmid:24238999 |
Schaefer C et al. | Fatty acid ethanolamide levels are altered in borderline personality and complex posttraumatic stress disorders. | 2014 | Eur Arch Psychiatry Clin Neurosci | pmid:24253425 |
Hoyer FF et al. | Inhibition of endocannabinoid-degrading enzyme fatty acid amide hydrolase increases atherosclerotic plaque vulnerability in mice. | 2014 | J. Mol. Cell. Cardiol. | pmid:24286707 |
Martinez-Vargas M et al. | Does the neuroprotective role of anandamide display diurnal variations? | 2013 | Int J Mol Sci | pmid:24287910 |
Jackson AR et al. | Characterization of endocannabinoid-mediated induction of myeloid-derived suppressor cells involving mast cells and MCP-1. | 2014 | J. Leukoc. Biol. | pmid:24319288 |
Vavilin VA et al. | Cytochrome P450 4F2 polymorphism in patients with liver cirrhosis. | 2013 | Bull. Exp. Biol. Med. | pmid:24319743 |
Gunduz-Cinar O et al. | Amygdala FAAH and anandamide: mediating protection and recovery from stress. | 2013 | Trends Pharmacol. Sci. | pmid:24325918 |
Bystrowska B et al. | Changes in endocannabinoid and N-acylethanolamine levels in rat brain structures following cocaine self-administration and extinction training. | 2014 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:24334211 |
Luce V et al. | The inhibitory effect of anandamide on oxytocin and vasopressin secretion from neurohypophysis is mediated by nitric oxide. | 2014 | Regul. Pept. | pmid:24342802 |
Oleson EB et al. | Cannabinoid receptor activation shifts temporally engendered patterns of dopamine release. | 2014 | Neuropsychopharmacology | pmid:24345819 |
Gesell FK et al. | Alterations of endocannabinoids in cerebrospinal fluid of dogs with epileptic seizure disorder. | 2013 | BMC Vet. Res. | pmid:24370333 |
Carr RL et al. | Low level chlorpyrifos exposure increases anandamide accumulation in juvenile rat brain in the absence of brain cholinesterase inhibition. | 2014 | Neurotoxicology | pmid:24373905 |
Fowler CJ | Has FLAT fallen flat? | 2014 | Trends Pharmacol. Sci. | pmid:24398120 |
Mahavadi S et al. | Inhibitory signaling by CB1 receptors in smooth muscle mediated by GRK5/β-arrestin activation of ERK1/2 and Src kinase. | 2014 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:24407588 |
Nicolussi S et al. | Guineensine is a novel inhibitor of endocannabinoid uptake showing cannabimimetic behavioral effects in BALB/c mice. | 2014 | Pharmacol. Res. | pmid:24412246 |
Leo LM et al. | Age-dependent relevance of endogenous 5-lipoxygenase derivatives in anxiety-like behavior in mice. | 2014 | PLoS ONE | pmid:24416334 |
Krishnan G and Chatterjee N | Endocannabinoids affect innate immunity of Muller glia during HIV-1 Tat cytotoxicity. | 2014 | Mol. Cell. Neurosci. | pmid:24418364 |
Thieme U et al. | Quantification of anandamide and 2-arachidonoylglycerol plasma levels to examine potential influences of tetrahydrocannabinol application on the endocannabinoid system in humans. | 2014 Jan-Feb | Drug Test Anal | pmid:24424856 |
pmid:24438603 | ||||
Kono M et al. | Design, synthesis, and biological evaluation of a series of piperazine ureas as fatty acid amide hydrolase inhibitors. | 2014 | Bioorg. Med. Chem. | pmid:24440478 |
Björklund E et al. | Ketoconazole inhibits the cellular uptake of anandamide via inhibition of FAAH at pharmacologically relevant concentrations. | 2014 | PLoS ONE | pmid:24466356 |
Al Kury LT et al. | Effects of endogenous cannabinoid anandamide on excitation-contraction coupling in rat ventricular myocytes. | 2014 | Cell Calcium | pmid:24472666 |
Sagie S et al. | [Short-and long-term effects of cannabinoids on memory, cognition and mental illness]. | 2013 | Harefuah | pmid:24483000 |
Sousa-Valente J et al. | Anandamide in primary sensory neurons: too much of a good thing? | 2014 | Eur. J. Neurosci. | pmid:24494681 |
Rea K et al. | Microinjection of 2-arachidonoyl glycerol into the rat ventral hippocampus differentially modulates contextually induced fear, depending on a persistent pain state. | 2014 | Eur. J. Neurosci. | pmid:24494683 |
pmid:24508153 | ||||
Zheng Y et al. | Dexamethasone alleviates motion sickness in rats in part by enhancing the endocannabinoid system. | 2014 | Eur. J. Pharmacol. | pmid:24508383 |
Rapino C et al. | Endocannabinoids as biomarkers of human reproduction. | 2014 Jul-Aug | Hum. Reprod. Update | pmid:24516083 |
Pava MJ et al. | Endocannabinoid modulation of cortical up-states and NREM sleep. | 2014 | PLoS ONE | pmid:24520411 |
Chiou LC et al. | Targeting the cannabinoid system for pain relief? | 2013 | Acta Anaesthesiol Taiwan | pmid:24529672 |
Sanson B et al. | Crystallographic study of FABP5 as an intracellular endocannabinoid transporter. | 2014 | Acta Crystallogr. D Biol. Crystallogr. | pmid:24531463 |
Okura D et al. | The endocannabinoid anandamide inhibits voltage-gated sodium channels Nav1.2, Nav1.6, Nav1.7, and Nav1.8 in Xenopus oocytes. | 2014 | Anesth. Analg. | pmid:24557103 |
Chianese R et al. | Hypothalamus-pituitary axis: an obligatory target for endocannabinoids to inhibit steroidogenesis in frog testis. | 2014 | Gen. Comp. Endocrinol. | pmid:24566122 |
Kwilasz AJ et al. | Effects of the fatty acid amide hydrolase inhibitor URB597 on pain-stimulated and pain-depressed behavior in rats. | 2014 | Behav Pharmacol | pmid:24583930 |
Gamage TF et al. | In-vivo pharmacological evaluation of the CB1-receptor allosteric modulator Org-27569. | 2014 | Behav Pharmacol | pmid:24603340 |
Engeli S et al. | Influence of dietary fat intake on the endocannabinoid system in lean and obese subjects. | 2014 | Obesity (Silver Spring) | pmid:24616451 |
Yu S et al. | Fatty acid-binding protein 5 (FABP5) regulates cognitive function both by decreasing anandamide levels and by activating the nuclear receptor peroxisome proliferator-activated receptor β/δ (PPARβ/δ) in the brain. | 2014 | J. Biol. Chem. | pmid:24644281 |
Basavarajappa BS et al. | Elevation of endogenous anandamide impairs LTP, learning, and memory through CB1 receptor signaling in mice. | 2014 | Hippocampus | pmid:24648181 |