Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Jergas B et al. | O-2050 facilitates noradrenaline release and increases the CB1 receptor inverse agonistic effect of rimonabant in the guinea pig hippocampus. | 2014 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:24853577 |
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Fowler CJ et al. | Inhibitory properties of ibuprofen and its amide analogues towards the hydrolysis and cyclooxygenation of the endocannabinoid anandamide. | 2013 | J Enzyme Inhib Med Chem | pmid:22225576 |
Ohsaka Y and Nishino H | 3T3-L1 adipocytes possess anandamide- and epinephrine-responsive machinery for MDM2 distribution to the plasma membrane. | 2013 | Gen. Physiol. Biophys. | pmid:23682023 |
Roy A et al. | Stress peptide PACAP engages multiple signaling pathways within the carotid body to initiate excitatory responses in respiratory and sympathetic chemosensory afferents. | 2013 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:23594614 |
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Marco EM et al. | Emotional, endocrine and brain anandamide response to social challenge in infant male rats. | 2013 | Psychoneuroendocrinology | pmid:23660109 |
Li Q et al. | Anandamide reduces intracellular Ca2+ concentration through suppression of Na+/Ca2+ exchanger current in rat cardiac myocytes. | 2013 | PLoS ONE | pmid:23667607 |
Lobato NS et al. | Reduced endothelium-dependent relaxation to anandamide in mesenteric arteries from young obese Zucker rats. | 2013 | PLoS ONE | pmid:23667622 |
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Lenglet S et al. | Fatty acid amide hydrolase deficiency enhances intraplaque neutrophil recruitment in atherosclerotic mice. | 2013 | Arterioscler. Thromb. Vasc. Biol. | pmid:23241405 |
Silva GB et al. | Anandamide inhibits transport-related oxygen consumption in the loop of Henle by activating CB1 receptors. | 2013 | Am. J. Physiol. Renal Physiol. | pmid:23220721 |
Citraro R et al. | Antiepileptic action of N-palmitoylethanolamine through CB1 and PPAR-α receptor activation in a genetic model of absence epilepsy. | 2013 | Neuropharmacology | pmid:23206503 |
Dékány A et al. | The contractile effect of anandamide in the guinea-pig small intestine is mediated by prostanoids but not TRPV1 receptors or capsaicin-sensitive nerves. | 2013 | Basic Clin. Pharmacol. Toxicol. | pmid:23216932 |
Romano MR and Lograno MD | Signaling cross-talk between cannabinoid and muscarinic systems actives Rho-kinase and increases the contractile responses of the bovine ciliary muscle. | 2013 | Eur. J. Pharmacol. | pmid:23396229 |
Romero TR et al. | CB1 and CB2 cannabinoid receptor agonists induce peripheral antinociception by activation of the endogenous noradrenergic system. | 2013 | Anesth. Analg. | pmid:23302980 |
Ho WS | Modulation by 17β-estradiol of anandamide vasorelaxation in normotensive and hypertensive rats: a role for TRPV1 but not fatty acid amide hydrolase. | 2013 | Eur. J. Pharmacol. | pmid:23340220 |
Zhuang J et al. | The interaction of fatty acid amide hydrolase (FAAH) inhibitors with an anandamide carrier protein using (19)F-NMR. | 2013 | AAPS J | pmid:23344792 |
Avraham Y et al. | Novel acylethanolamide derivatives that modulate body weight through enhancement of hypothalamic pro-opiomelanocortin (POMC) and/or decreased neuropeptide Y (NPY). | 2013 | J. Med. Chem. | pmid:23384387 |
Gebeh AK et al. | Elevated anandamide and related N-acylethanolamine levels occur in the peripheral blood of women with ectopic pregnancy and are mirrored by changes in peripheral fatty acid amide hydrolase activity. | 2013 | J. Clin. Endocrinol. Metab. | pmid:23372171 |
Compagnucci C et al. | Type-1 (CB1) cannabinoid receptor promotes neuronal differentiation and maturation of neural stem cells. | 2013 | PLoS ONE | pmid:23372698 |
Lee TT et al. | Temporal changes in N-acylethanolamine content and metabolism throughout the peri-adolescent period. | 2013 | Synapse | pmid:22987804 |
Han B et al. | Quantitative LC-MS/MS analysis of arachidonoyl amino acids in mouse brain with treatment of FAAH inhibitor. | 2013 | Anal. Biochem. | pmid:23044255 |
Pedroza-Llinás R et al. | CB1 receptor activation in the nucleus accumbens core impairs contextual fear learning. | 2013 | Behav. Brain Res. | pmid:23018128 |
Li Q et al. | Anandamide enhances expression of heat shock protein 72 to protect against ischemia-reperfusion injury in rat heart. | 2013 | J Physiol Sci | pmid:23007622 |
Rivera P et al. | Diet-dependent modulation of hippocampal expression of endocannabinoid signaling-related proteins in cannabinoid antagonist-treated obese rats. | 2013 | Eur. J. Neurosci. | pmid:23033907 |
Starowicz K et al. | Full inhibition of spinal FAAH leads to TRPV1-mediated analgesic effects in neuropathic rats and possible lipoxygenase-mediated remodeling of anandamide metabolism. | 2013 | PLoS ONE | pmid:23573230 |
Subbanna S et al. | Anandamide-CB1 receptor signaling contributes to postnatal ethanol-induced neonatal neurodegeneration, adult synaptic, and memory deficits. | 2013 | J. Neurosci. | pmid:23575834 |
Descalzi F et al. | Platelet-rich plasma exerts antinociceptive activity by a peripheral endocannabinoid-related mechanism. | 2013 | Tissue Eng Part A | pmid:23578218 |
Morgan CJ et al. | Cerebrospinal fluid anandamide levels, cannabis use and psychotic-like symptoms. | 2013 | Br J Psychiatry | pmid:23580381 |
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Seillier A et al. | Phencyclidine-induced social withdrawal results from deficient stimulation of cannabinoid CBâ‚ receptors: implications for schizophrenia. | 2013 | Neuropsychopharmacology | pmid:23563893 |
Derbenev AV and Smith BN | Dexamethasone rapidly increases GABA release in the dorsal motor nucleus of the vagus via retrograde messenger-mediated enhancement of TRPV1 activity. | 2013 | PLoS ONE | pmid:23936221 |
Krumbholz A et al. | Diagnostic value of concentration profiles of glucocorticosteroids and endocannabinoids in hair. | 2013 | Ther Drug Monit | pmid:23942543 |
Liu J et al. | Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24191036 |
Hill MN et al. | Reductions in circulating endocannabinoid levels in individuals with post-traumatic stress disorder following exposure to the World Trade Center attacks. | 2013 | Psychoneuroendocrinology | pmid:24035186 |
Marichal-Cancino BA et al. | Analysis of anandamide- and lysophosphatidylinositol-induced inhibition of the vasopressor responses produced by sympathetic stimulation or noradrenaline in pithed rats. | 2013 | Eur. J. Pharmacol. | pmid:24076186 |
Akerman S et al. | Endocannabinoids in the brainstem modulate dural trigeminovascular nociceptive traffic via CB1 and "triptan" receptors: implications in migraine. | 2013 | J. Neurosci. | pmid:24027286 |
Adinolfi B et al. | Anticancer activity of anandamide in human cutaneous melanoma cells. | 2013 | Eur. J. Pharmacol. | pmid:24041928 |
Fonseca BM et al. | The endocannabinoid anandamide induces apoptosis of rat decidual cells through a mechanism involving ceramide synthesis and p38 MAPK activation. | 2013 | Apoptosis | pmid:24048885 |
Khlaifia A et al. | Anandamide, cannabinoid type 1 receptor, and NMDA receptor activation mediate non-Hebbian presynaptically expressed long-term depression at the first central synapse for visceral afferent fibers. | 2013 | J. Neurosci. | pmid:23904599 |
Citraro R et al. | CB1 agonists, locally applied to the cortico-thalamic circuit of rats with genetic absence epilepsy, reduce epileptic manifestations. | 2013 | Epilepsy Res. | pmid:23860329 |
Bernabò N et al. | Systems biology analysis of the endocannabinoid system reveals a scale-free network with distinct roles for anandamide and 2-arachidonoylglycerol. | 2013 | OMICS | pmid:24117401 |
Wenzel D et al. | Endocannabinoid anandamide mediates hypoxic pulmonary vasoconstriction. | 2013 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24167249 |
Vavilin VA et al. | Cytochrome P450 4F2 polymorphism in patients with liver cirrhosis. | 2013 | Bull. Exp. Biol. Med. | pmid:24319743 |
Leung K et al. | Role of FAAH-like anandamide transporter in anandamide inactivation. | 2013 | PLoS ONE | pmid:24223930 |
Maione S et al. | Piperazinyl carbamate fatty acid amide hydrolase inhibitors and transient receptor potential channel modulators as "dual-target" analgesics. | 2013 | Pharmacol. Res. | pmid:23911581 |
Jourdan T et al. | Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes. | 2013 | Nat. Med. | pmid:23955712 |
O'Brien LD et al. | Anandamide transport inhibition by ARN272 attenuates nausea-induced behaviour in rats, and vomiting in shrews (Suncus murinus). | 2013 | Br. J. Pharmacol. | pmid:23991698 |