Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Orthostatic Intolerance D054971 1 associated lipids
Sleep Disorders, Intrinsic D020919 1 associated lipids
Headache Disorders, Secondary D051271 1 associated lipids
Somatosensory Disorders D020886 1 associated lipids
Amnesia, Anterograde D020324 2 associated lipids
Substance-Related Disorders D019966 2 associated lipids
Ocular Hypotension D015814 2 associated lipids
Vascular System Injuries D057772 2 associated lipids
Schistosomiasis japonica D012554 3 associated lipids
Bulimia D002032 3 associated lipids
Acute Pain D059787 3 associated lipids
Cardiovirus Infections D018188 3 associated lipids
Impotence, Vasculogenic D018783 4 associated lipids
Urinary Bladder Diseases D001745 4 associated lipids
Urinary Incontinence D014549 4 associated lipids
Picornaviridae Infections D010850 4 associated lipids
Fibromyalgia D005356 4 associated lipids
Intestinal Pseudo-Obstruction D007418 5 associated lipids
Pregnancy, Ectopic D011271 5 associated lipids
Muscle Spasticity D009128 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Authors Title Published Journal PubMed Link
Koga D et al. Liquid chromatographic-atmospheric pressure chemical ionization mass spectrometric determination of anandamide and its analogs in rat brain and peripheral tissues. 1997 J. Chromatogr. B Biomed. Sci. Appl. pmid:9106024
Beltramo M et al. Inhibition of anandamide hydrolysis in rat brain tissue by (E)-6-(bromomethylene) tetrahydro-3-(1-naphthalenyl)-2H-pyran-2-one. 1997 FEBS Lett. pmid:9091314
Deutsch DG et al. Fatty acid sulfonyl fluorides inhibit anandamide metabolism and bind to the cannabinoid receptor. 1997 Biochem. Biophys. Res. Commun. pmid:9070252
De Petrocellis L et al. Novel inhibitors of brain, neuronal, and basophilic anandamide amidohydrolase. 1997 Biochem. Biophys. Res. Commun. pmid:9070224
Bisogno T et al. Biosynthesis, release and degradation of the novel endogenous cannabimimetic metabolite 2-arachidonoylglycerol in mouse neuroblastoma cells. 1997 Biochem. J. pmid:9065792
Thumser AE et al. A fluorescence displacement assay for the measurement of arachidonoyl ethanolamide (anandamide) and oleoyl amide (octadecenoamide) hydrolysis. 1997 Biochem. Pharmacol. pmid:9065749
Fowler CJ et al. Ibuprofen inhibits the metabolism of the endogenous cannabimimetic agent anandamide. 1997 Pharmacol. Toxicol. pmid:9060042
Sheskin T et al. Structural requirements for binding of anandamide-type compounds to the brain cannabinoid receptor. 1997 J. Med. Chem. pmid:9057852
Berdyshev EV et al. Anandamide--a new look on fatty acid ethanolamides. 1996 J Lipid Mediat Cell Signal pmid:9029374
Bisogno T et al. Biosynthesis, uptake, and degradation of anandamide and palmitoylethanolamide in leukocytes. 1997 J. Biol. Chem. pmid:9013571
Cadas H et al. Occurrence and biosynthesis of endogenous cannabinoid precursor, N-arachidonoyl phosphatidylethanolamine, in rat brain. 1997 J. Neurosci. pmid:9006968
Romero J et al. Time-course of the effects of anandamide, the putative endogenous cannabinoid receptor ligand, on extrapyramidal function. 1995 Brain Res. pmid:8974649
Randall MD et al. An endogenous cannabinoid as an endothelium-derived vasorelaxant. 1996 Biochem. Biophys. Res. Commun. pmid:8954092
Sugiura T et al. 2-Arachidonoylglycerol, a putative endogenous cannabinoid receptor ligand, induces rapid, transient elevation of intracellular free Ca2+ in neuroblastoma x glioma hybrid NG108-15 cells. 1996 Biochem. Biophys. Res. Commun. pmid:8954083
Poling JS et al. Anandamide, an endogenous cannabinoid, inhibits Shaker-related voltage-gated K+ channels. 1996 Neuropharmacology pmid:8938728
Boring DL et al. Cerebrodiene, arachidonyl-ethanolamide, and hybrid structures: potential for interaction with brain cannabinoid receptors. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8931121
Paria BC et al. The uterus is a potential site for anandamide synthesis and hydrolysis: differential profiles of anandamide synthase and hydrolase activities in the mouse uterus during the periimplantation period. 1996 Mol. Reprod. Dev. pmid:8914076
Ueda N et al. Enzymes for anandamide biosynthesis and metabolism. 1996 J Lipid Mediat Cell Signal pmid:8906546
Sugiura T et al. N-arachidonoylethanolamine (anandamide), an endogenous cannabinoid receptor ligand, and related lipid molecules in the nervous tissues. 1996 J Lipid Mediat Cell Signal pmid:8906545
Shimasue K et al. Effects of anandamide and arachidonic acid on specific binding of (+) -PN200-110, diltiazem and (-) -desmethoxyverapamil to L-type Ca2+ channel. 1996 Eur. J. Pharmacol. pmid:8904088