| MeSH term | MeSH ID | Detail |
|---|---|---|
| Alzheimer Disease | D000544 | 76 associated lipids |
| Anorexia | D000855 | 8 associated lipids |
| Arthritis, Experimental | D001169 | 24 associated lipids |
| Ataxia | D001259 | 20 associated lipids |
| Urinary Bladder Diseases | D001745 | 4 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Bradycardia | D001919 | 13 associated lipids |
| Brain Concussion | D001924 | 5 associated lipids |
| Brain Damage, Chronic | D001925 | 6 associated lipids |
| Brain Edema | D001929 | 20 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Bronchial Spasm | D001986 | 18 associated lipids |
| Bulimia | D002032 | 3 associated lipids |
| Cardiomyopathy, Dilated | D002311 | 15 associated lipids |
| Catalepsy | D002375 | 30 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Ischemic Attack, Transient | D002546 | 42 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kim J and Alger BE | Inhibition of cyclooxygenase-2 potentiates retrograde endocannabinoid effects in hippocampus. | 2004 | Nat. Neurosci. | pmid:15184902 |
| Marsicano G and Chaouloff F | Moving bliss: a new anandamide transporter. | 2012 | Nat. Neurosci. | pmid:22193249 |
| Self DW | Anandamide: a candidate neurotransmitter heads for the big leagues. | 1999 | Nat. Neurosci. | pmid:10204533 |
| Giuffrida A et al. | Dopamine activation of endogenous cannabinoid signaling in dorsal striatum. | 1999 | Nat. Neurosci. | pmid:10204543 |
| Kim J and Alger BE | Reduction in endocannabinoid tone is a homeostatic mechanism for specific inhibitory synapses. | 2010 | Nat. Neurosci. | pmid:20348918 |
| Maccarrone M et al. | Anandamide inhibits metabolism and physiological actions of 2-arachidonoylglycerol in the striatum. | 2008 | Nat. Neurosci. | pmid:18204441 |
| Di Marzo V | Anandamide serves two masters in the brain. | 2010 | Nat. Neurosci. | pmid:21102567 |
| Clapper JR et al. | Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism. | 2010 | Nat. Neurosci. | pmid:20852626 |
| Di Marzo V | Endocannabinoid signaling in the brain: biosynthetic mechanisms in the limelight. | 2011 | Nat. Neurosci. | pmid:21187849 |
| Chávez AE et al. | TRPV1 activation by endogenous anandamide triggers postsynaptic long-term depression in dentate gyrus. | 2010 | Nat. Neurosci. | pmid:21076423 |
| Fu J et al. | A catalytically silent FAAH-1 variant drives anandamide transport in neurons. | 2012 | Nat. Neurosci. | pmid:22101642 |
| Gerdeman GL et al. | Postsynaptic endocannabinoid release is critical to long-term depression in the striatum. | 2002 | Nat. Neurosci. | pmid:11976704 |
| Balas L et al. | Synthesis of a photoactivatable probe of the anandamide re-uptake. | 2005 | Nat. Prod. Res. | pmid:15938150 |
| Mechoulam R et al. | Anandamide may mediate sleep induction. | 1997 | Nature | pmid:9288961 |
| Hohmann AG et al. | An endocannabinoid mechanism for stress-induced analgesia. | 2005 | Nature | pmid:15973410 |
| Iversen L | Pharmacology. Endogenous cannabinoids. | 1994 | Nature | pmid:7990950 |
| Calignano A et al. | Control of pain initiation by endogenous cannabinoids. | 1998 | Nature | pmid:9685157 |
| Di Marzo V et al. | Formation and inactivation of endogenous cannabinoid anandamide in central neurons. | 1994 | Nature | pmid:7990962 |
| Zygmunt PM et al. | Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. | 1999 | Nature | pmid:10440374 |
| Iversen LL | Pharmacology. Medical uses of marijuana? | 1993 | Nature | pmid:8395659 |
| Munro S et al. | Molecular characterization of a peripheral receptor for cannabinoids. | 1993 | Nature | pmid:7689702 |
| Premkumar LS and Ahern GP | Induction of vanilloid receptor channel activity by protein kinase C. | 2000 Dec 21-28 | Nature | pmid:11140687 |
| di Tomaso E et al. | Brain cannabinoids in chocolate. | 1996 | Nature | pmid:8751435 |
| RodrÃguez de Fonseca F et al. | An anorexic lipid mediator regulated by feeding. | 2001 | Nature | pmid:11700558 |
| Davis JB et al. | Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia. | 2000 | Nature | pmid:10821274 |
| Venance L et al. | Inhibition by anandamide of gap junctions and intercellular calcium signalling in striatal astrocytes. | 1995 | Nature | pmid:7637807 |
| Watanabe H et al. | Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels. | 2003 | Nature | pmid:12879072 |
| Cravatt BF et al. | Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides. | 1996 | Nature | pmid:8900284 |
| Calignano A et al. | Bidirectional control of airway responsiveness by endogenous cannabinoids. | 2000 | Nature | pmid:11081515 |
| Mechoulam R and Fride E | Physiology. A hunger for cannabinoids. | 2001 | Nature | pmid:11298428 |
| Mechoulam R | Todd's achievement. | 1997 | Nature | pmid:9126725 |
| Wagner JA et al. | Activation of peripheral CB1 cannabinoid receptors in haemorrhagic shock. | 1997 | Nature | pmid:9394002 |
| Stella N et al. | A second endogenous cannabinoid that modulates long-term potentiation. | 1997 | Nature | pmid:9285589 |
| Barthó L et al. | Nitric oxide is involved in the relaxant effect of capsaicin in the human sigmoid colon circular muscle. | 2002 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:12382081 |
| Holt S and Fowler CJ | Anandamide metabolism by fatty acid amide hydrolase in intact C6 glioma cells. Increased sensitivity to inhibition by ibuprofen and flurbiprofen upon reduction of extra- but not intracellular pH. | 2003 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:12644895 |
| Schulte K et al. | Cannabinoid CB1 receptor activation, pharmacological blockade, or genetic ablation affects the function of the muscarinic auto- and heteroreceptor. | 2012 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:22215206 |
| del Carmen GarcÃa M et al. | Hypotensive effect of anandamide through the activation of CB1 and VR1 spinal receptors in urethane-anesthetized rats. | 2003 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:14504685 |
| Baranowska-Kuczko M et al. | Mechanisms of endothelium-dependent relaxation evoked by anandamide in isolated human pulmonary arteries. | 2014 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:24682422 |
| Molderings GJ et al. | Presynaptic cannabinoid and imidazoline receptors in the human heart and their potential relationship. | 1999 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:10494885 |
| Akinshola BE et al. | Anandamide inhibition of recombinant AMPA receptor subunits in Xenopus oocytes is increased by forskolin and 8-bromo-cyclic AMP. | 1999 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:10543424 |
| Fisar Z | Inhibition of monoamine oxidase activity by cannabinoids. | 2010 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:20401651 |
| Malinowska B et al. | Involvement of central beta2-adrenergic, NMDA and thromboxane A2 receptors in the pressor effect of anandamide in rats. | 2010 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:20198363 |
| Terranova JP et al. | Inhibition of long-term potentiation in rat hippocampal slices by anandamide and WIN55212-2: reversal by SR141716 A, a selective antagonist of CB1 cannabinoid receptors. | 1995 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:8751088 |
| Zygmunt PM et al. | Differential actions of anandamide, potassium ions and endothelium-derived hyperpolarizing factor in guinea-pig basilar artery. | 2000 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:10832608 |
| Ilayan E et al. | Do cannabinoids exhibit a tyramine-like effect? | 2013 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:23900610 |
| Avelino A and Cruz F | TRPV1 (vanilloid receptor) in the urinary tract: expression, function and clinical applications. | 2006 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:16721555 |
| Jergas B et al. | O-2050 facilitates noradrenaline release and increases the CB1 receptor inverse agonistic effect of rimonabant in the guinea pig hippocampus. | 2014 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:24853577 |
| Steffens M et al. | Quantitative measurement of depolarization-induced anandamide release in human and rat neocortex. | 2003 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:14566450 |
| Kracke GR et al. | The cannabinoid receptor agonists, anandamide and WIN 55,212-2, do not directly affect mu opioid receptors expressed in Xenopus oocytes. | 2007 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:17960365 |
| Crozier Willi G et al. | Lipids in neural function: modulation of behavior by oral administration of endocannabinoids found in foods. | 2001 | Nestle Nutr Workshop Ser Clin Perform Programme | pmid:11510437 |