| MeSH term | MeSH ID | Detail |
|---|---|---|
| Alzheimer Disease | D000544 | 76 associated lipids |
| Anorexia | D000855 | 8 associated lipids |
| Arthritis, Experimental | D001169 | 24 associated lipids |
| Ataxia | D001259 | 20 associated lipids |
| Urinary Bladder Diseases | D001745 | 4 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Bradycardia | D001919 | 13 associated lipids |
| Brain Concussion | D001924 | 5 associated lipids |
| Brain Damage, Chronic | D001925 | 6 associated lipids |
| Brain Edema | D001929 | 20 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Bronchial Spasm | D001986 | 18 associated lipids |
| Bulimia | D002032 | 3 associated lipids |
| Cardiomyopathy, Dilated | D002311 | 15 associated lipids |
| Catalepsy | D002375 | 30 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Ischemic Attack, Transient | D002546 | 42 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Malek N et al. | Anandamide, Acting via CB2 Receptors, Alleviates LPS-Induced Neuroinflammation in Rat Primary Microglial Cultures. | 2015 | Neural Plast. | pmid:26090232 |
| Mechoulam R | The promise of advances in the field of endocannabinoids. | 2004 Feb-Apr | Neuro Endocrinol. Lett. | pmid:15159675 |
| Fride E | The endocannabinoid-CB receptor system: Importance for development and in pediatric disease. | 2004 Feb-Apr | Neuro Endocrinol. Lett. | pmid:15159678 |
| Russo EB | Clinical endocannabinoid deficiency (CECD): can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions? | 2004 Feb-Apr | Neuro Endocrinol. Lett. | pmid:15159679 |
| Wise LE et al. | Fatty acid amide hydrolase (FAAH) knockout mice exhibit enhanced acquisition of an aversive, but not of an appetitive, Barnes maze task. | 2009 | Neurobiol Learn Mem | pmid:19524055 |
| Munguba H et al. | Pre-training anandamide infusion within the basolateral amygdala impairs plus-maze discriminative avoidance task in rats. | 2011 | Neurobiol Learn Mem | pmid:21440651 |
| De Oliveira Alvares L et al. | Differential role of the hippocampal endocannabinoid system in the memory consolidation and retrieval mechanisms. | 2008 | Neurobiol Learn Mem | pmid:18342551 |
| Costanzi M et al. | Effects of anandamide and morphine combinations on memory consolidation in cd1 mice: involvement of dopaminergic mechanisms. | 2004 | Neurobiol Learn Mem | pmid:14990234 |
| Costanzi M et al. | Anandamide and memory in CD1 mice: effects of immobilization stress and of prior experience. | 2003 | Neurobiol Learn Mem | pmid:12676519 |
| Jung KM et al. | An amyloid β42-dependent deficit in anandamide mobilization is associated with cognitive dysfunction in Alzheimer's disease. | 2012 | Neurobiol. Aging | pmid:21546126 |
| Navarro M and RodrÃguez de Fonseca F | The neurobiology of cannabinoid transmission: from anandamide signaling to higher cerebral functions and disease. | 1998 | Neurobiol. Dis. | pmid:9974172 |
| Di Marzo V and Deutsch DG | Biochemistry of the endogenous ligands of cannabinoid receptors. | 1998 | Neurobiol. Dis. | pmid:9974173 |
| Piomelli D et al. | Endogenous cannabinoid signaling. | 1998 | Neurobiol. Dis. | pmid:9974178 |
| Vázquez C et al. | Endocannabinoids regulate the activity of astrocytic hemichannels and the microglial response against an injury: In vivo studies. | 2015 | Neurobiol. Dis. | pmid:25917763 |
| Hawkins V and Butt A | TASK-1 channels in oligodendrocytes: a role in ischemia mediated disruption. | 2013 | Neurobiol. Dis. | pmid:23567653 |
| Garcia-Ovejero D et al. | The endocannabinoid system is modulated in response to spinal cord injury in rats. | 2009 | Neurobiol. Dis. | pmid:18930143 |
| Meuth SG et al. | The neuroprotective impact of the leak potassium channel TASK1 on stroke development in mice. | 2009 | Neurobiol. Dis. | pmid:18930826 |
| Khasabova IA et al. | Increased anandamide uptake by sensory neurons contributes to hyperalgesia in a model of cancer pain. | 2013 | Neurobiol. Dis. | pmid:23644187 |
| Cabranes A et al. | Decreased endocannabinoid levels in the brain and beneficial effects of agents activating cannabinoid and/or vanilloid receptors in a rat model of multiple sclerosis. | 2005 | Neurobiol. Dis. | pmid:16242629 |
| Bardell TK and Barker EL | Activation of TRPC6 channels promotes endocannabinoid biosynthesis in neuronal CAD cells. | 2010 | Neurochem. Int. | pmid:20466028 |
| Vinod KY et al. | Effect of chronic ethanol exposure and its withdrawal on the endocannabinoid system. | 2006 | Neurochem. Int. | pmid:16822589 |
| Sang N et al. | Anandamide potentiation of miniature spontaneous excitatory synaptic transmission is mediated via IP3 pathway. | 2010 | Neurochem. Int. | pmid:20064571 |
| Molderings GJ et al. | Noradrenaline release-inhibiting receptors on PC12 cells devoid of alpha(2(-)) and CB(1) receptors: similarities to presynaptic imidazoline and edg receptors. | 2002 | Neurochem. Int. | pmid:11738482 |
| Cannizzaro C et al. | Presynaptic effects of anandamide and WIN55,212-2 on glutamatergic nerve endings isolated from rat hippocampus. | 2006 | Neurochem. Int. | pmid:16325966 |
| D'Amico M et al. | Inhibition by anandamide and synthetic cannabimimetics of the release of [3H]D-aspartate and [3H]GABA from synaptosomes isolated from the rat hippocampus. | 2004 | Neurochem. Res. | pmid:15260134 |
| Bazinet RP et al. | Rapid high-energy microwave fixation is required to determine the anandamide (N-arachidonoylethanolamine) concentration of rat brain. | 2005 | Neurochem. Res. | pmid:16176062 |
| Bloom AS et al. | Nonclassical and endogenous cannabinoids: effects on the ordering of brain membranes. | 1997 | Neurochem. Res. | pmid:9131634 |
| Axelrod J and Felder CC | Cannabinoid receptors and their endogenous agonist, anandamide. | 1998 | Neurochem. Res. | pmid:9566594 |
| Weidenfeld J et al. | Effect of the brain constituent anandamide, a cannabinoid receptor agonist, on the hypothalamo-pituitary-adrenal axis in the rat. | 1994 | Neuroendocrinology | pmid:8127398 |
| Osei-Hyiaman D et al. | Cocaine- and amphetamine-related transcript is involved in the orexigenic effect of endogenous anandamide. | 2005 | Neuroendocrinology | pmid:16131814 |
| Wenger T et al. | The endogenous cannabinoid, anandamide, activates the hypothalamo-pituitary-adrenal axis in CB1 cannabinoid receptor knockout mice. | 2003 | Neuroendocrinology | pmid:14688442 |
| Yuece B et al. | Cannabinoid type 1 receptor modulates intestinal propulsion by an attenuation of intestinal motor responses within the myenteric part of the peristaltic reflex. | 2007 | Neurogastroenterol. Motil. | pmid:17727394 |
| Terry G et al. | Positron emission tomography imaging using an inverse agonist radioligand to assess cannabinoid CB1 receptors in rodents. | 2008 | Neuroimage | pmid:18456516 |
| Rettori E et al. | Anti-inflammatory effect of the endocannabinoid anandamide in experimental periodontitis and stress in the rat. | 2012 | Neuroimmunomodulation | pmid:22777139 |
| Rettori V et al. | Endocannabinoids in TNF-alpha and ethanol actions. | 2007 | Neuroimmunomodulation | pmid:18073513 |
| Centonze D et al. | Lack of effect of cannabis-based treatment on clinical and laboratory measures in multiple sclerosis. | 2009 | Neurol. Sci. | pmid:19768368 |
| Centonze D et al. | Altered anandamide degradation in attention-deficit/hyperactivity disorder. | 2009 | Neurology | pmid:19398708 |
| Tanimura A et al. | The endocannabinoid 2-arachidonoylglycerol produced by diacylglycerol lipase alpha mediates retrograde suppression of synaptic transmission. | 2010 | Neuron | pmid:20159446 |
| Eljaschewitsch E et al. | The endocannabinoid anandamide protects neurons during CNS inflammation by induction of MKP-1 in microglial cells. | 2006 | Neuron | pmid:16387640 |
| Weller K et al. | TRPV1, TRPA1, and CB1 in the isolated vagus nerve--axonal chemosensitivity and control of neuropeptide release. | 2011 | Neuropeptides | pmid:21868092 |
| Engel MA et al. | Inhibitory CB1 and activating/desensitizing TRPV1-mediated cannabinoid actions on CGRP release in rodent skin. | 2011 | Neuropeptides | pmid:21514666 |
| Kurjak M et al. | Differential stimulatory effects of cannabinoids on VIP release and NO synthase activity in synaptosomal fractions from rat ileum. | 2008 Oct-Dec | Neuropeptides | pmid:18829105 |
| Breivogel CS et al. | Cannabinoid signaling in rat cerebellar granule cells: G-protein activation, inhibition of glutamate release and endogenous cannabinoids. | 2004 | Neuropharmacology | pmid:15165836 |
| Hillard CJ and Jarrahian A | Accumulation of anandamide: evidence for cellular diversity. | 2005 | Neuropharmacology | pmid:15910883 |
| Starowicz K et al. | Spinal anandamide produces analgesia in neuropathic rats: possible CB(1)- and TRPV1-mediated mechanisms. | 2012 | Neuropharmacology | pmid:22178705 |
| Citraro R et al. | Antiepileptic action of N-palmitoylethanolamine through CB1 and PPAR-α receptor activation in a genetic model of absence epilepsy. | 2013 | Neuropharmacology | pmid:23206503 |
| Roberts LA et al. | Methanandamide activation of a novel current in mouse trigeminal ganglion sensory neurons in vitro. | 2008 | Neuropharmacology | pmid:17631916 |
| Vela G et al. | Anandamide decreases naloxone-precipitated withdrawal signs in mice chronically treated with morphine. | 1995 | Neuropharmacology | pmid:7566503 |
| Rueda-Orozco PE et al. | Impairment of endocannabinoids activity in the dorsolateral striatum delays extinction of behavior in a procedural memory task in rats. | 2008 | Neuropharmacology | pmid:18501388 |
| Placzek EA et al. | Membrane microdomains and metabolic pathways that define anandamide and 2-arachidonyl glycerol biosynthesis and breakdown. | 2008 | Neuropharmacology | pmid:18760289 |