Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Breast Neoplasms D001943 24 associated lipids
Neoplasms D009369 13 associated lipids
Pain D010146 64 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Fatty Liver D005234 48 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Hypotension D007022 41 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Melanoma D008545 69 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Authors Title Published Journal PubMed Link
Derkinderen P et al. Regulation of a neuronal form of focal adhesion kinase by anandamide. 1996 Science pmid:8781236
Shimasue K et al. Effects of anandamide and arachidonic acid on specific binding of (+) -PN200-110, diltiazem and (-) -desmethoxyverapamil to L-type Ca2+ channel. 1996 Eur. J. Pharmacol. pmid:8904088
Sugiura T et al. Enzymatic synthesis of anandamide, an endogenous cannabinoid receptor ligand, through N-acylphosphatidylethanolamine pathway in testis: involvement of Ca(2+)-dependent transacylase and phosphodiesterase activities. 1996 Biochem. Biophys. Res. Commun. pmid:8573114
Jarho P et al. Hydroxypropyl-beta-cyclodextrin increases aqueous solubility and stability of anandamide. 1996 Life Sci. pmid:8602110
Skaper SD et al. The ALIAmide palmitoylethanolamide and cannabinoids, but not anandamide, are protective in a delayed postglutamate paradigm of excitotoxic death in cerebellar granule neurons. 1996 Proc. Natl. Acad. Sci. U.S.A. pmid:8633002
Wise ML et al. Synthesis and cannabinoid receptor binding activity of conjugated triene anandamide, a novel eicosanoid. 1996 Experientia pmid:8575565
Pan X et al. Rat brain cannabinoid receptor modulates N-type Ca2+ channels in a neuronal expression system. 1996 Mol. Pharmacol. pmid:8609900
Fride E and Mechoulam R Developmental aspects of anandamide: ontogeny of response and prenatal exposure. 1996 Psychoneuroendocrinology pmid:8774060
Shivachar AC et al. Anandamide- and delta9-tetrahydrocannabinol-evoked arachidonic acid mobilization and blockade by SR141716A [N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4 -methyl-1H-pyrazole-3-carboximide hydrochloride]. 1996 Biochem. Pharmacol. pmid:8615904
Fride E and Mechoulam R Ontogenetic development of the response to anandamide and delta 9-tetrahydrocannabinol in mice. 1996 Brain Res. Dev. Brain Res. pmid:8873985
Sugiura T et al. 2-Arachidonoylglycerol, a putative endogenous cannabinoid receptor ligand, induces rapid, transient elevation of intracellular free Ca2+ in neuroblastoma x glioma hybrid NG108-15 cells. 1996 Biochem. Biophys. Res. Commun. pmid:8954083
Stein EA et al. Physiological and behavioural effects of the endogenous cannabinoid, arachidonylethanolamide (anandamide), in the rat. 1996 Br. J. Pharmacol. pmid:8872363
James JS Marijuana and chocolate. 1996 AIDS Treat News pmid:11363932
Thomas BF et al. Structure-activity analysis of anandamide analogs: relationship to a cannabinoid pharmacophore. 1996 J. Med. Chem. pmid:8558515
Randall MD et al. An endogenous cannabinoid as an endothelium-derived vasorelaxant. 1996 Biochem. Biophys. Res. Commun. pmid:8954092
Paria BC et al. The uterus is a potential site for anandamide synthesis and hydrolysis: differential profiles of anandamide synthase and hydrolase activities in the mouse uterus during the periimplantation period. 1996 Mol. Reprod. Dev. pmid:8914076
Khanolkar AD et al. Head group analogs of arachidonylethanolamide, the endogenous cannabinoid ligand. 1996 J. Med. Chem. pmid:8893848
Sugiura T et al. Transacylase-mediated and phosphodiesterase-mediated synthesis of N-arachidonoylethanolamine, an endogenous cannabinoid-receptor ligand, in rat brain microsomes. Comparison with synthesis from free arachidonic acid and ethanolamine. 1996 Eur. J. Biochem. pmid:8797835
Koga D et al. High-performance liquid chromatography and fluorometric detection of arachidonylethanolamide (anandamide) and its analogues, derivatized with 4-(N-chloroformylmethyl-N-methyl)amino-7-N,N-dimethylaminosulp honyl-2,1 ,3- benzoxadiazole (DBD-COCl). 1995 Jan-Feb Biomed. Chromatogr. pmid:7734936
Edgemond WS et al. The binding of novel phenolic derivatives of anandamide to brain cannabinoid receptors. 1995 Feb-Mar Prostaglandins Leukot. Essent. Fatty Acids pmid:7784462