Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Breast Neoplasms D001943 24 associated lipids
Neoplasms D009369 13 associated lipids
Pain D010146 64 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Fatty Liver D005234 48 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Hypotension D007022 41 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Melanoma D008545 69 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Piomelli D et al. Structural determinants for recognition and translocation by the anandamide transporter. 1999 Proc. Natl. Acad. Sci. U.S.A. pmid:10318965
Brown WH et al. Fatty acid amide hydrolase ablation promotes ectopic lipid storage and insulin resistance due to centrally mediated hypothyroidism. 2012 Proc. Natl. Acad. Sci. U.S.A. pmid:22912404
Scorticati C et al. The inhibitory effect of anandamide on luteinizing hormone-releasing hormone secretion is reversed by estrogen. 2004 Proc. Natl. Acad. Sci. U.S.A. pmid:15280536
Boger DL et al. Exceptionally potent inhibitors of fatty acid amide hydrolase: the enzyme responsible for degradation of endogenous oleamide and anandamide. 2000 Proc. Natl. Acad. Sci. U.S.A. pmid:10805767
De Petrocellis L et al. The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation. 1998 Proc. Natl. Acad. Sci. U.S.A. pmid:9653194
Fegley D et al. Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM1172. 2004 Proc. Natl. Acad. Sci. U.S.A. pmid:15138300
Facci L et al. Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide. 1995 Proc. Natl. Acad. Sci. U.S.A. pmid:7724569
Skaper SD et al. The ALIAmide palmitoylethanolamide and cannabinoids, but not anandamide, are protective in a delayed postglutamate paradigm of excitotoxic death in cerebellar granule neurons. 1996 Proc. Natl. Acad. Sci. U.S.A. pmid:8633002
Mukhopadhyay B et al. Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver. 2011 Proc. Natl. Acad. Sci. U.S.A. pmid:21383171
Izzo AA and Deutsch DG Unique pathway for anandamide synthesis and liver regeneration. 2011 Proc. Natl. Acad. Sci. U.S.A. pmid:21490298
Zhang N et al. A proinflammatory chemokine, CCL3, sensitizes the heat- and capsaicin-gated ion channel TRPV1. 2005 Proc. Natl. Acad. Sci. U.S.A. pmid:15764707
Paria BC et al. The preimplantation mouse embryo is a target for cannabinoid ligand-receptor signaling. 1995 Proc. Natl. Acad. Sci. U.S.A. pmid:7568154
Berger A et al. Anandamide and diet: inclusion of dietary arachidonate and docosahexaenoate leads to increased brain levels of the corresponding N-acylethanolamines in piglets. 2001 Proc. Natl. Acad. Sci. U.S.A. pmid:11353819
Liu J et al. Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase. 2013 Proc. Natl. Acad. Sci. U.S.A. pmid:24191036
Wenzel D et al. Endocannabinoid anandamide mediates hypoxic pulmonary vasoconstriction. 2013 Proc. Natl. Acad. Sci. U.S.A. pmid:24167249
Gobbi G et al. Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis. 2005 Proc. Natl. Acad. Sci. U.S.A. pmid:16352709
Schmid PC et al. Changes in anandamide levels in mouse uterus are associated with uterine receptivity for embryo implantation. 1997 Proc. Natl. Acad. Sci. U.S.A. pmid:9108127
Klein TW et al. The cannabinoid system and cytokine network. 2000 Proc. Soc. Exp. Biol. Med. pmid:10998193
Calignano A et al. A role for the endogenous cannabinoid system in the peripheral control of pain initiation. 2000 Prog. Brain Res. pmid:11098711
Brown I et al. Cannabinoids and omega-3/6 endocannabinoids as cell death and anticancer modulators. 2013 Prog. Lipid Res. pmid:23103355