Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

Cross Reference

Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Breast Neoplasms D001943 24 associated lipids
Neoplasms D009369 13 associated lipids
Pain D010146 64 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Fatty Liver D005234 48 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Hypotension D007022 41 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Melanoma D008545 69 associated lipids
Per page 10 20 50 100 | Total 105

PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

Download all related citations
Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Greco R et al. Alterations of the endocannabinoid system in an animal model of migraine: evaluation in cerebral areas of rat. 2010 Cephalalgia pmid:19515121
Amorós I et al. Endocannabinoids and cannabinoid analogues block human cardiac Kv4.3 channels in a receptor-independent manner. 2010 J. Mol. Cell. Cardiol. pmid:19616555
Roser P et al. Potential antipsychotic properties of central cannabinoid (CB1) receptor antagonists. 2010 World J. Biol. Psychiatry pmid:20218784
Musella A et al. Transient receptor potential vanilloid 1 channels control acetylcholine/2-arachidonoylglicerol coupling in the striatum. 2010 Neuroscience pmid:20219639
Caraceni P et al. Circulating and hepatic endocannabinoids and endocannabinoid-related molecules in patients with cirrhosis. 2010 Liver Int. pmid:19840245
Buznikov GA et al. A putative 'pre-nervous' endocannabinoid system in early echinoderm development. 2010 Dev. Neurosci. pmid:19907129
Kaczocha M et al. Lipid droplets are novel sites of N-acylethanolamine inactivation by fatty acid amide hydrolase-2. 2010 J. Biol. Chem. pmid:19926788
Aquila S et al. Human sperm anatomy: ultrastructural localization of the cannabinoid1 receptor and a potential role of anandamide in sperm survival and acrosome reaction. 2010 Anat Rec (Hoboken) pmid:19938110
Osman NA et al. Synthesis, binding studies and molecular modeling of novel cannabinoid receptor ligands. 2010 Bioorg. Med. Chem. pmid:21074998
Xie S et al. Inactivation of lipid glyceryl ester metabolism in human THP1 monocytes/macrophages by activated organophosphorus insecticides: role of carboxylesterases 1 and 2. 2010 Chem. Res. Toxicol. pmid:21049984
Amoako AA et al. Quantitative analysis of anandamide and related acylethanolamides in human seminal plasma by ultra performance liquid chromatography tandem mass spectrometry. 2010 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:21056015
Godlewski G et al. Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effects. 2010 Chem. Biol. pmid:21095576
Di Marzo V Anandamide serves two masters in the brain. 2010 Nat. Neurosci. pmid:21102567
Zakrzeska A et al. A cannabinoid receptor, sensitive to O-1918, is involved in the delayed hypotension induced by anandamide in anaesthetized rats. 2010 Br. J. Pharmacol. pmid:20105178
Kozono S et al. Involvement of the endocannabinoid system in periodontal healing. 2010 Biochem. Biophys. Res. Commun. pmid:20233580
Yang YY et al. Mechanisms of TNFalpha-induced cardiac dysfunction in cholestatic bile duct-ligated mice: interaction between TNFalpha and endocannabinoids. 2010 J. Hepatol. pmid:20626112
Lisboa SF et al. Cannabinoid CB1 receptors in the medial prefrontal cortex modulate the expression of contextual fear conditioning. 2010 Int. J. Neuropsychopharmacol. pmid:20587131
Thors L et al. Biochanin A, a naturally occurring inhibitor of fatty acid amide hydrolase. 2010 Br. J. Pharmacol. pmid:20590565
Mukhopadhyay P et al. CB1 cannabinoid receptors promote oxidative/nitrosative stress, inflammation and cell death in a murine nephropathy model. 2010 Br. J. Pharmacol. pmid:20590569
Rajesh M et al. Cannabinoid-1 receptor activation induces reactive oxygen species-dependent and -independent mitogen-activated protein kinase activation and cell death in human coronary artery endothelial cells. 2010 Br. J. Pharmacol. pmid:20590572
Wheal AJ et al. Vasorelaxation to N-oleoylethanolamine in rat isolated arteries: mechanisms of action and modulation via cyclooxygenase activity. 2010 Br. J. Pharmacol. pmid:20590573
Gutierrez-Lopez MD et al. Involvement of 2-arachidonoyl glycerol in the increased consumption of and preference for ethanol of mice treated with neurotoxic doses of methamphetamine. 2010 Br. J. Pharmacol. pmid:20590579
Soneji ND et al. Effects of cannabinoids on capsaicin receptor activity following exposure of primary sensory neurons to inflammatory mediators. 2010 Life Sci. pmid:20598325
Lam PM et al. Simultaneous measurement of three N-acylethanolamides in human bio-matrices using ultra performance liquid chromatography-tandem mass spectrometry. 2010 Anal Bioanal Chem pmid:20835819
Muccioli GG et al. The endocannabinoid system links gut microbiota to adipogenesis. 2010 Mol. Syst. Biol. pmid:20664638
Clapper JR et al. Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism. 2010 Nat. Neurosci. pmid:20852626
Ribeiro A et al. Anandamide prior to sensitization increases cell-mediated immunity in mice. 2010 Int. Immunopharmacol. pmid:20093200
Cencioni MT et al. Anandamide suppresses proliferation and cytokine release from primary human T-lymphocytes mainly via CB2 receptors. 2010 PLoS ONE pmid:20098669
Oz M et al. The endogenous cannabinoid, anandamide, inhibits dopamine transporter function by a receptor-independent mechanism. 2010 J. Neurochem. pmid:20050977
Yang Q et al. Anandamide induces cell death through lipid rafts in hepatic stellate cells. 2010 J. Gastroenterol. Hepatol. pmid:20059638
Sang N et al. Anandamide potentiation of miniature spontaneous excitatory synaptic transmission is mediated via IP3 pathway. 2010 Neurochem. Int. pmid:20064571
Aquila S et al. Rimonabant (SR141716) induces metabolism and acquisition of fertilizing ability in human sperm. 2010 Br. J. Pharmacol. pmid:20067470
El-Talatini MR et al. The relationship between plasma levels of the endocannabinoid, anandamide, sex steroids, and gonadotrophins during the menstrual cycle. 2010 Fertil. Steril. pmid:19200965
Gratzke C et al. Localization and function of cannabinoid receptors in the corpus cavernosum: basis for modulation of nitric oxide synthase nerve activity. 2010 Eur. Urol. pmid:19147270
Prieto D Editorial comment on: localization and function of cannabinoid receptors in the corpus cavernosum: basis for modulation of nitric oxide synthase nerve activity. 2010 Eur. Urol. pmid:19147273
Prestifilippo JP et al. Role of the endocannabinoid system in ethanol-induced inhibition of salivary secretion. 2009 Sep-Oct Alcohol Alcohol. pmid:19589828
Marco EM et al. Long-term consequences of URB597 administration during adolescence on cannabinoid CB1 receptor binding in brain areas. 2009 Brain Res. pmid:19133243
Ho WS and Gardiner SM Acute hypertension reveals depressor and vasodilator effects of cannabinoids in conscious rats. 2009 Br. J. Pharmacol. pmid:19133994
Doroshenko P and Renaud LP Acid-sensitive TASK-like K+ conductances contribute to resting membrane potential and to orexin-induced membrane depolarization in rat thalamic paraventricular nucleus neurons. 2009 Neuroscience pmid:19135504
Koethe D et al. Sleep deprivation increases oleoylethanolamide in human cerebrospinal fluid. 2009 J Neural Transm pmid:19137236
Adermark L et al. Endocannabinoid-dependent plasticity at GABAergic and glutamatergic synapses in the striatum is regulated by synaptic activity. 2009 Eur. J. Neurosci. pmid:19120438
Wang J and Ueda N Biology of endocannabinoid synthesis system. 2009 Prostaglandins Other Lipid Mediat. pmid:19126434
Acone G et al. Low type I cannabinoid receptor levels characterize placental villous in labouring delivery. 2009 Placenta pmid:19097644
Wheal AJ and Randall MD Effects of hypertension on vasorelaxation to endocannabinoids in vitro. 2009 Eur. J. Pharmacol. pmid:19100733
Oddi S et al. Molecular identification of albumin and Hsp70 as cytosolic anandamide-binding proteins. 2009 Chem. Biol. pmid:19481477
Reis GM et al. Opioid receptor and NO/cGMP pathway as a mechanism of peripheral antinociceptive action of the cannabinoid receptor agonist anandamide. 2009 Life Sci. pmid:19576231
Umathe SN et al. Endocannabinoids mediate anxiolytic-like effect of acetaminophen via CB1 receptors. 2009 Prog. Neuropsychopharmacol. Biol. Psychiatry pmid:19580839
Murakami T et al. Antimicrobial cathelicidin polypeptide CAP11 suppresses the production and release of septic mediators in D-galactosamine-sensitized endotoxin shock mice. 2009 Int. Immunol. pmid:19556302
Palandra J et al. Endogenous ethanolamide analysis in human plasma using HPLC tandem MS with electrospray ionization. 2009 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:19535304
Fonseca BM et al. Anandamide-induced cell death: dual effects in primary rat decidual cell cultures. 2009 Placenta pmid:19560819
Guasti L et al. Minocycline treatment inhibits microglial activation and alters spinal levels of endocannabinoids in a rat model of neuropathic pain. 2009 Mol Pain pmid:19570201
Bittner S et al. TASK1 modulates inflammation and neurodegeneration in autoimmune inflammation of the central nervous system. 2009 Brain pmid:19570851
Snider NT et al. A cytochrome P450-derived epoxygenated metabolite of anandamide is a potent cannabinoid receptor 2-selective agonist. 2009 Mol. Pharmacol. pmid:19171674
Grimaldi P et al. The endocannabinoid system and pivotal role of the CB2 receptor in mouse spermatogenesis. 2009 Proc. Natl. Acad. Sci. U.S.A. pmid:19541620
Grider JR et al. Modulation of motor and sensory pathways of the peristaltic reflex by cannabinoids. 2009 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:19589944
Ahn K et al. Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain. 2009 Chem. Biol. pmid:19389627
Yates ML and Barker EL Inactivation and biotransformation of the endogenous cannabinoids anandamide and 2-arachidonoylglycerol. 2009 Mol. Pharmacol. pmid:19389920
Miyato H et al. Pharmacological synergism between cannabinoids and paclitaxel in gastric cancer cell lines. 2009 J. Surg. Res. pmid:19394652
Hill MN et al. Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress. 2009 Psychoneuroendocrinology pmid:19394765
Chen L et al. Endogenous anandamide and cannabinoid receptor-2 contribute to electroacupuncture analgesia in rats. 2009 J Pain pmid:19409856
Yang YY et al. Inhibition of hepatic tumour necrosis factor-alpha attenuates the anandamide-induced vasoconstrictive response in cirrhotic rat livers. 2009 Liver Int. pmid:19413671
Hansen HS and Diep TA N-acylethanolamines, anandamide and food intake. 2009 Biochem. Pharmacol. pmid:19413995
Zoerner AA et al. Targeted stable-isotope dilution GC-MS/MS analysis of the endocannabinoid anandamide and other fatty acid ethanol amides in human plasma. 2009 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:19414283
Di Pasquale E et al. The insertion and transport of anandamide in synthetic lipid membranes are both cholesterol-dependent. 2009 PLoS ONE pmid:19330032
Trezza V and Vanderschuren LJ Divergent effects of anandamide transporter inhibitors with different target selectivity on social play behavior in adolescent rats. 2009 J. Pharmacol. Exp. Ther. pmid:18948500
Carney ST et al. Cannabinoid regulation of nitric oxide synthase I (nNOS) in neuronal cells. 2009 J Neuroimmune Pharmacol pmid:19365734
Gervasi MG et al. The endocannabinoid system in bull sperm and bovine oviductal epithelium: role of anandamide in sperm-oviduct interaction. 2009 Reproduction pmid:19042982
Mendiguren A and Pineda J Effect of the CB(1) receptor antagonists rimonabant and AM251 on the firing rate of dorsal raphe nucleus neurons in rat brain slices. 2009 Br. J. Pharmacol. pmid:19845674
Guindon J and Beaulieu P The role of the endogenous cannabinoid system in peripheral analgesia. 2009 Curr Mol Pharmacol pmid:20021453
Fonseca BM et al. Spatio-temporal expression patterns of anandamide-binding receptors in rat implantation sites: evidence for a role of the endocannabinoid system during the period of placental development. 2009 Reprod. Biol. Endocrinol. pmid:19860893
Abalo R et al. Postnatal maturation of the gastrointestinal tract: a functional and immunohistochemical study in the guinea-pig ileum at weaning. 2009 Neurosci. Lett. pmid:19819299
Bradshaw HB et al. The endocannabinoid anandamide is a precursor for the signaling lipid N-arachidonoyl glycine by two distinct pathways. 2009 BMC Biochem. pmid:19460156
Järbe TU et al. Discriminative stimulus functions in rats of AM1346, a high-affinity CB1R selective anandamide analog. 2009 Psychopharmacology (Berl.) pmid:18521574
Bajo M et al. Differential alteration of hippocampal excitatory synaptic transmission by cannabinoid ligands. 2009 J. Neurosci. Res. pmid:18816788
Long JZ et al. Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects. 2009 Nat. Chem. Biol. pmid:19029917
Navarrete CM et al. Opposite effects of anandamide and N-arachidonoyl dopamine in the regulation of prostaglandin E and 8-iso-PGF formation in primary glial cells. 2009 J. Neurochem. pmid:19200337
Tang B et al. Endothelin-1 inhibits background two-pore domain channel TASK-1 in primary human pulmonary artery smooth muscle cells. 2009 Am. J. Respir. Cell Mol. Biol. pmid:19188660
Ribeiro ML et al. 17beta-oestradiol and progesterone regulate anandamide synthesis in the rat uterus. 2009 Reprod. Biomed. Online pmid:19192341
Vural IM et al. Functional characterization of nonadrenergic noncholinergic neurotransmitter release via endocannabinoids: an in vitro study in rabbit corpus cavernosum. 2009 J Sex Med pmid:19175867
Garcia-Ovejero D et al. The endocannabinoid system is modulated in response to spinal cord injury in rats. 2009 Neurobiol. Dis. pmid:18930143
Musella A et al. TRPV1 channels facilitate glutamate transmission in the striatum. 2009 Mol. Cell. Neurosci. pmid:18930149
Meuth SG et al. The neuroprotective impact of the leak potassium channel TASK1 on stroke development in mice. 2009 Neurobiol. Dis. pmid:18930826
Sun X et al. Genetic loss of Faah compromises male fertility in mice. 2009 Biol. Reprod. pmid:18987328
Long JZ et al. Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo. 2009 Proc. Natl. Acad. Sci. U.S.A. pmid:19918051
Hong S et al. Reciprocal changes in vanilloid (TRPV1) and endocannabinoid (CB1) receptors contribute to visceral hyperalgesia in the water avoidance stressed rat. 2009 Gut pmid:18936104
McMahon LR Apparent affinity estimates of rimonabant in combination with anandamide and chemical analogs of anandamide in rhesus monkeys discriminating Delta9-tetrahydrocannabinol. 2009 Psychopharmacology (Berl.) pmid:18592221
Kaczocha M et al. Identification of intracellular carriers for the endocannabinoid anandamide. 2009 Proc. Natl. Acad. Sci. U.S.A. pmid:19307565
Alenmyr L et al. TRPV1-mediated itch in seasonal allergic rhinitis. 2009 Allergy pmid:19220220
García-García F et al. Sleep-inducing factors. 2009 CNS Neurol Disord Drug Targets pmid:19689305
Pasquariello N et al. Characterization of the endocannabinoid system in human neuronal cells and proteomic analysis of anandamide-induced apoptosis. 2009 J. Biol. Chem. pmid:19690173
Schroeder C et al. Circulating endocannabinoid concentrations during orthostatic stress. 2009 Clin. Auton. Res. pmid:19756829
Hill MN et al. Suppression of amygdalar endocannabinoid signaling by stress contributes to activation of the hypothalamic-pituitary-adrenal axis. 2009 Neuropsychopharmacology pmid:19710634
Yusifzade K et al. The protective role of anandamide in mesenteric ischemia reperfusion injury in guinea pig. 2009 Bratisl Lek Listy pmid:19711821
Thors L and Fowler CJ Effect of nitric oxide donors on membrane tritium accumulation of endocannabinoids and related endogenous lipids. 2009 Eur. J. Pharmacol. pmid:19715690
Kaufmann I et al. Enhanced anandamide plasma levels in patients with complex regional pain syndrome following traumatic injury: a preliminary report. 2009 Eur Surg Res pmid:19729930
Shinohara Y et al. Cannabinoid in the nucleus accumbens enhances the intake of palatable solution. 2009 Neuroreport pmid:19734811
Campos AC and Guimarães FS Evidence for a potential role for TRPV1 receptors in the dorsolateral periaqueductal gray in the attenuation of the anxiolytic effects of cannabinoids. 2009 Prog. Neuropsychopharmacol. Biol. Psychiatry pmid:19735690
Tuboly G et al. The antinociceptive interaction of anandamide and adenosine at the spinal level. 2009 Pharmacol. Biochem. Behav. pmid:18760296
Hydock DS et al. Anandamide preserves cardiac function and geometry in an acute doxorubicin cardiotoxicity rat model. 2009 J. Cardiovasc. Pharmacol. Ther. pmid:19129423
Lin YS et al. Sensitization of capsaicin-sensitive lung vagal afferents by anandamide in rats: role of transient receptor potential vanilloid 1 receptors. 2009 J. Appl. Physiol. pmid:19131477