Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
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Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kondo S et al. | Accumulation of various N-acylethanolamines including N-arachidonoylethanolamine (anandamide) in cadmium chloride-administered rat testis. | 1998 | Arch. Biochem. Biophys. | pmid:9637740 |
| Maccarrone M et al. | Lipopolysaccharide downregulates fatty acid amide hydrolase expression and increases anandamide levels in human peripheral lymphocytes. | 2001 | Arch. Biochem. Biophys. | pmid:11556820 |
| D'Souza DC and Kosten TR | Cannabinoid antagonists: a treatment in search of an illness. | 2001 | Arch. Gen. Psychiatry | pmid:11296092 |
| Fernandez-Solari J et al. | Participation of the endocannabinoid system in lipopolysaccharide-induced inhibition of salivary secretion. | 2010 | Arch. Oral Biol. | pmid:20542488 |
| Jonsson KO et al. | AM404 and VDM 11 non-specifically inhibit C6 glioma cell proliferation at concentrations used to block the cellular accumulation of the endocannabinoid anandamide. | 2003 | Arch. Toxicol. | pmid:12698235 |
| Andersson M et al. | Neurotoxicity of glutamate in chick telencephalon neurons: reduction of toxicity by preincubation with carbachol, but not by the endogenous fatty acid amides anandamide and palmitoylethanolamide. | 2000 | Arch. Toxicol. | pmid:10877002 |
| Gustafsson SB et al. | Effects of cannabinoids and related fatty acids upon the viability of P19 embryonal carcinoma cells. | 2013 | Arch. Toxicol. | pmid:23552853 |
| Lenglet S et al. | Fatty acid amide hydrolase deficiency enhances intraplaque neutrophil recruitment in atherosclerotic mice. | 2013 | Arterioscler. Thromb. Vasc. Biol. | pmid:23241405 |
| Richardson D et al. | Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis. | 2008 | Arthritis Res. Ther. | pmid:18416822 |
| Lowin T et al. | Cortisol-mediated adhesion of synovial fibroblasts is dependent on the degradation of anandamide and activation of the endocannabinoid system. | 2012 | Arthritis Rheum. | pmid:22933357 |
| Sagar DR et al. | Tonic modulation of spinal hyperexcitability by the endocannabinoid receptor system in a rat model of osteoarthritis pain. | 2010 | Arthritis Rheum. | pmid:20722027 |
| Sakamoto Y et al. | Effectiveness of continuous hemodiafiltration using a polymethylmethacrylate membrane hemofilter after polymyxin B-immobilized fiber column therapy of septic shock. | 2008 Jan-Feb | ASAIO J. | pmid:18204329 |
| Sakamoto Y et al. | Clinical responses and improvement of some laboratory parameters following polymyxin B-immobilized fiber treatment in septic shock. | 2007 Sep-Oct | ASAIO J. | pmid:17885340 |
| Marichal-Cancino BA et al. | Role of pre-junctional CB1, but not CB2 , TRPV1 or GPR55 receptors in anandamide-induced inhibition of the vasodepressor sensory CGRPergic outflow in pithed rats. | 2014 | Basic Clin. Pharmacol. Toxicol. | pmid:24118786 |
| Dékány A et al. | The contractile effect of anandamide in the guinea-pig small intestine is mediated by prostanoids but not TRPV1 receptors or capsaicin-sensitive nerves. | 2013 | Basic Clin. Pharmacol. Toxicol. | pmid:23216932 |
| Yeh JH et al. | Effect of anandamide on cytosolic Ca(2+) levels and proliferation in canine renal tubular cells. | 2006 | Basic Clin. Pharmacol. Toxicol. | pmid:16623868 |
| Gamage TF et al. | In-vivo pharmacological evaluation of the CB1-receptor allosteric modulator Org-27569. | 2014 | Behav Pharmacol | pmid:24603340 |
| Kwilasz AJ et al. | Effects of the fatty acid amide hydrolase inhibitor URB597 on pain-stimulated and pain-depressed behavior in rats. | 2014 | Behav Pharmacol | pmid:24583930 |
| Castellano C et al. | The effects of anandamide on memory consolidation in mice involve both D1 and D2 dopamine receptors. | 1997 | Behav Pharmacol | pmid:9832956 |
| Castellano C et al. | Strain-dependent effects of anandamide on memory consolidation in mice are antagonized by naltrexone. | 1999 | Behav Pharmacol | pmid:10780251 |