Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Scotchie JG et al. | Endocannabinoid regulation in human endometrium across the menstrual cycle. | 2015 | Reprod Sci | pmid:24819878 |
Luce V et al. | The inhibitory effect of anandamide on oxytocin and vasopressin secretion from neurohypophysis is mediated by nitric oxide. | 2014 | Regul. Pept. | pmid:24342802 |
Nakata M and Yada T | Cannabinoids inhibit insulin secretion and cytosolic Ca2+ oscillation in islet beta-cells via CB1 receptors. | 2008 | Regul. Pept. | pmid:17884194 |
Shaladi AM et al. | [Cannabinoids in the control of pain]. | 2008 | Recenti Prog Med | pmid:19388223 |
Qi M et al. | A robust capillary liquid chromatography/tandem mass spectrometry method for quantitation of neuromodulatory endocannabinoids. | 2015 | Rapid Commun. Mass Spectrom. | pmid:26411510 |
Dudášová A et al. | The effects of cannabidiol on the antigen-induced contraction of airways smooth muscle in the guinea-pig. | 2013 | Pulm Pharmacol Ther | pmid:23428645 |
Schindler CW et al. | Self-administration of the anandamide transport inhibitor AM404 by squirrel monkeys. | 2016 | Psychopharmacology (Berl.) | pmid:26803499 |
Naidu PS et al. | Evaluation of fatty acid amide hydrolase inhibition in murine models of emotionality. | 2007 | Psychopharmacology (Berl.) | pmid:17279376 |
Panlilio LV et al. | Effects of fatty acid amide hydrolase (FAAH) inhibitors on working memory in rats. | 2016 | Psychopharmacology (Berl.) | pmid:26558620 |
Egashira N et al. | Anandamide inhibits the DOI-induced head-twitch response in mice. | 2004 | Psychopharmacology (Berl.) | pmid:14586538 |
Williams CM and Kirkham TC | Anandamide induces overeating: mediation by central cannabinoid (CB1) receptors. | 1999 | Psychopharmacology (Berl.) | pmid:10353436 |
Fernandez-Espejo E and Galan-Rodriguez B | Sensorimotor gating in mice is disrupted after AM404, an anandamide reuptake and degradation inhibitor. | 2004 | Psychopharmacology (Berl.) | pmid:15088080 |
Vlachou S et al. | Effects of endocannabinoid neurotransmission modulators on brain stimulation reward. | 2006 | Psychopharmacology (Berl.) | pmid:16953388 |
Mallet PE and Beninger RJ | The cannabinoid CB1 receptor antagonist SR141716A attenuates the memory impairment produced by delta9-tetrahydrocannabinol or anandamide. | 1998 | Psychopharmacology (Berl.) | pmid:9862397 |
Cassano T et al. | Evaluation of the emotional phenotype and serotonergic neurotransmission of fatty acid amide hydrolase-deficient mice. | 2011 | Psychopharmacology (Berl.) | pmid:21042794 |
Higgs S et al. | Cannabinoid influences on palatability: microstructural analysis of sucrose drinking after delta(9)-tetrahydrocannabinol, anandamide, 2-arachidonoyl glycerol and SR141716. | 2003 | Psychopharmacology (Berl.) | pmid:12447606 |
Cross-Mellor SK et al. | Effects of the FAAH inhibitor, URB597, and anandamide on lithium-induced taste reactivity responses: a measure of nausea in the rat. | 2007 | Psychopharmacology (Berl.) | pmid:17111174 |
Gorzalka BB et al. | Endocannabinoid modulation of male rat sexual behavior. | 2008 | Psychopharmacology (Berl.) | pmid:17694389 |
Rueda-Orozco PE et al. | A potential function of endocannabinoids in the selection of a navigation strategy by rats. | 2008 | Psychopharmacology (Berl.) | pmid:17805517 |
Sustkova-Fiserova M et al. | Ghrelin and endocannabinoids participation in morphine-induced effects in the rat nucleus accumbens. | 2016 | Psychopharmacology (Berl.) | pmid:26507196 |
Morera-Herreras T et al. | Nigrostriatal denervation changes the effect of cannabinoids on subthalamic neuronal activity in rats. | 2011 | Psychopharmacology (Berl.) | pmid:20959968 |
Solinas M et al. | Dopaminergic augmentation of delta-9-tetrahydrocannabinol (THC) discrimination: possible involvement of D(2)-induced formation of anandamide. | 2010 | Psychopharmacology (Berl.) | pmid:20179908 |
Costa B et al. | Precipitated and spontaneous withdrawal in rats tolerant to anandamide. | 2000 | Psychopharmacology (Berl.) | pmid:10805606 |
Llorente-Berzal A et al. | 2-AG promotes the expression of conditioned fear via cannabinoid receptor type 1 on GABAergic neurons. | 2015 | Psychopharmacology (Berl.) | pmid:25814137 |
Haller J et al. | The effects of anandamide signaling enhanced by the FAAH inhibitor URB597 on coping styles in rats. | 2013 | Psychopharmacology (Berl.) | pmid:23743650 |
Fogaça MV et al. | Effects of glutamate NMDA and TRPV1 receptor antagonists on the biphasic responses to anandamide injected into the dorsolateral periaqueductal grey of Wistar rats. | 2013 | Psychopharmacology (Berl.) | pmid:23183551 |
Aliczki M et al. | Involvement of 2-arachidonoylglycerol signaling in social challenge responding of male CD1 mice. | 2015 | Psychopharmacology (Berl.) | pmid:25547462 |
Järbe TU et al. | Discriminative stimulus functions in rats of AM1346, a high-affinity CB1R selective anandamide analog. | 2009 | Psychopharmacology (Berl.) | pmid:18521574 |
Resstel LB et al. | Activation of CB1 cannabinoid receptors in the dorsolateral periaqueductal gray reduces the expression of contextual fear conditioning in rats. | 2008 | Psychopharmacology (Berl.) | pmid:18446325 |
Cippitelli A et al. | Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat. | 2008 | Psychopharmacology (Berl.) | pmid:18446329 |
McMahon LR | Apparent affinity estimates of rimonabant in combination with anandamide and chemical analogs of anandamide in rhesus monkeys discriminating Delta9-tetrahydrocannabinol. | 2009 | Psychopharmacology (Berl.) | pmid:18592221 |
Limebeer CL et al. | Attenuation of anticipatory nausea in a rat model of contextually elicited conditioned gaping by enhancement of the endocannabinoid system. | 2014 | Psychopharmacology (Berl.) | pmid:24043345 |
Mangieri RA et al. | An endocannabinoid signal associated with desire for alcohol is suppressed in recently abstinent alcoholics. | 2009 | Psychopharmacology (Berl.) | pmid:19343330 |
Panlilio LV et al. | Anandamide-induced behavioral disruption through a vanilloid-dependent mechanism in rats. | 2009 | Psychopharmacology (Berl.) | pmid:19015836 |
Schacht JP et al. | Intermediate cannabis dependence phenotypes and the FAAH C385A variant: an exploratory analysis. | 2009 | Psychopharmacology (Berl.) | pmid:19002671 |
Heyman E et al. | Intense exercise increases circulating endocannabinoid and BDNF levels in humans--possible implications for reward and depression. | 2012 | Psychoneuroendocrinology | pmid:22029953 |
Hill MN et al. | Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress. | 2009 | Psychoneuroendocrinology | pmid:19394765 |
Gray JM et al. | Sustained glucocorticoid exposure recruits cortico-limbic CRH signaling to modulate endocannabinoid function. | 2016 | Psychoneuroendocrinology | pmid:26821211 |
Marco EM et al. | Emotional, endocrine and brain anandamide response to social challenge in infant male rats. | 2013 | Psychoneuroendocrinology | pmid:23660109 |
Fride E and Mechoulam R | Developmental aspects of anandamide: ontogeny of response and prenatal exposure. | 1996 | Psychoneuroendocrinology | pmid:8774060 |
Kaufmann I et al. | Anandamide and neutrophil function in patients with fibromyalgia. | 2008 | Psychoneuroendocrinology | pmid:18395993 |
Hill MN et al. | Reductions in circulating endocannabinoid levels in individuals with post-traumatic stress disorder following exposure to the World Trade Center attacks. | 2013 | Psychoneuroendocrinology | pmid:24035186 |
Basavarajappa BS | Critical enzymes involved in endocannabinoid metabolism. | 2007 | Protein Pept. Lett. | pmid:17346227 |
Mimeault M et al. | Anti-proliferative and apoptotic effects of anandamide in human prostatic cancer cell lines: implication of epidermal growth factor receptor down-regulation and ceramide production. | 2003 | Prostate | pmid:12746841 |
Chen P et al. | Metabolism of anandamide in cerebral microvascular endothelial cells. | 2004 | Prostaglandins Other Lipid Mediat. | pmid:15165032 |
Kim HY et al. | A synaptogenic amide N-docosahexaenoylethanolamide promotes hippocampal development. | 2011 | Prostaglandins Other Lipid Mediat. | pmid:21810478 |
Hillard CJ | Biochemistry and pharmacology of the endocannabinoids arachidonylethanolamide and 2-arachidonylglycerol. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10785538 |
Burstein SH et al. | Oxidative metabolism of anandamide. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10785540 |
Di Marzo V et al. | Cannabimimetic fatty acid derivatives in cancer and inflammation. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10785541 |
McCue JM et al. | In vitro synthesis of arachidonoyl amino acids by cytochrome c. | 2009 | Prostaglandins Other Lipid Mediat. | pmid:19683594 |