Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
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Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Bornheim LM et al. | Microsomal cytochrome P450-mediated liver and brain anandamide metabolism. | 1995 | Biochem. Pharmacol. | pmid:7669071 |
| Hillard CJ et al. | Characterization of the kinetics and distribution of N-arachidonylethanolamine (anandamide) hydrolysis by rat brain. | 1995 | Biochim. Biophys. Acta | pmid:7647100 |
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| Welch SP et al. | Characterization of anandamide- and fluoroanandamide-induced antinociception and cross-tolerance to delta 9-THC after intrathecal administration to mice: blockade of delta 9-THC-induced antinociception. | 1995 | J. Pharmacol. Exp. Ther. | pmid:7791096 |
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| Adams IB et al. | Pharmacological and behavioral evaluation of alkylated anandamide analogs. | 1995 | Life Sci. | pmid:7776830 |
| Wenger T et al. | Effects of anandamide (endogen cannabinoid) on anterior pituitary hormone secretion in adult ovariectomized rats. | 1995 | Life Sci. | pmid:7776832 |
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| Hampson AJ et al. | Anandamide hydroxylation by brain lipoxygenase:metabolite structures and potencies at the cannabinoid receptor. | 1995 | Biochim. Biophys. Acta | pmid:7488638 |
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| Maurelli S et al. | Two novel classes of neuroactive fatty acid amides are substrates for mouse neuroblastoma 'anandamide amidohydrolase'. | 1995 | FEBS Lett. | pmid:8543025 |
| Pate DW et al. | Ophthalmic arachidonylethanolamide decreases intraocular pressure in normotensive rabbits. | 1995 | Curr. Eye Res. | pmid:8529418 |
| Vela G et al. | Anandamide decreases naloxone-precipitated withdrawal signs in mice chronically treated with morphine. | 1995 | Neuropharmacology | pmid:7566503 |
| Paria BC et al. | The preimplantation mouse embryo is a target for cannabinoid ligand-receptor signaling. | 1995 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7568154 |
| Burstein SH and Hunter SA | Stimulation of anandamide biosynthesis in N-18TG2 neuroblastoma cells by delta 9-tetrahydrocannabinol (THC). | 1995 | Biochem. Pharmacol. | pmid:7702643 |
| Priller J et al. | Mead ethanolamide, a novel eicosanoid, is an agonist for the central (CB1) and peripheral (CB2) cannabinoid receptors. | 1995 | Mol. Pharmacol. | pmid:7651362 |
| Ellis EF et al. | Anandamide and delta 9-THC dilation of cerebral arterioles is blocked by indomethacin. | 1995 | Am. J. Physiol. | pmid:8594893 |
| Pertwee RG et al. | Effect of phenylmethylsulphonyl fluoride on the potency of anandamide as an inhibitor of electrically evoked contractions in two isolated tissue preparations. | 1995 | Eur. J. Pharmacol. | pmid:7713152 |
| Hansen HS et al. | Glutamate stimulates the formation of N-acylphosphatidylethanolamine and N-acylethanolamine in cortical neurons in culture. | 1995 | Biochim. Biophys. Acta | pmid:7548201 |
| Romero J et al. | Time-course of the effects of anandamide, the putative endogenous cannabinoid receptor ligand, on extrapyramidal function. | 1995 | Brain Res. | pmid:8974649 |
| Ueda N et al. | Lipoxygenase-catalyzed oxygenation of arachidonylethanolamide, a cannabinoid receptor agonist. | 1995 | Biochim. Biophys. Acta | pmid:7827116 |
| Edgemond WS et al. | The binding of novel phenolic derivatives of anandamide to brain cannabinoid receptors. | 1995 Feb-Mar | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7784462 |
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| Shimasue K et al. | Effects of anandamide and arachidonic acid on specific binding of (+) -PN200-110, diltiazem and (-) -desmethoxyverapamil to L-type Ca2+ channel. | 1996 | Eur. J. Pharmacol. | pmid:8904088 |
| Sugiura T et al. | Enzymatic synthesis of anandamide, an endogenous cannabinoid receptor ligand, through N-acylphosphatidylethanolamine pathway in testis: involvement of Ca(2+)-dependent transacylase and phosphodiesterase activities. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8573114 |
| Jarho P et al. | Hydroxypropyl-beta-cyclodextrin increases aqueous solubility and stability of anandamide. | 1996 | Life Sci. | pmid:8602110 |
| Skaper SD et al. | The ALIAmide palmitoylethanolamide and cannabinoids, but not anandamide, are protective in a delayed postglutamate paradigm of excitotoxic death in cerebellar granule neurons. | 1996 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8633002 |
| Wise ML et al. | Synthesis and cannabinoid receptor binding activity of conjugated triene anandamide, a novel eicosanoid. | 1996 | Experientia | pmid:8575565 |
| Pan X et al. | Rat brain cannabinoid receptor modulates N-type Ca2+ channels in a neuronal expression system. | 1996 | Mol. Pharmacol. | pmid:8609900 |
| Fride E and Mechoulam R | Developmental aspects of anandamide: ontogeny of response and prenatal exposure. | 1996 | Psychoneuroendocrinology | pmid:8774060 |
| Showalter VM et al. | Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): identification of cannabinoid receptor subtype selective ligands. | 1996 | J. Pharmacol. Exp. Ther. | pmid:8819477 |
| Shivachar AC et al. | Anandamide- and delta9-tetrahydrocannabinol-evoked arachidonic acid mobilization and blockade by SR141716A [N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4 -methyl-1H-pyrazole-3-carboximide hydrochloride]. | 1996 | Biochem. Pharmacol. | pmid:8615904 |
| Sugiura T et al. | 2-Arachidonoylglycerol, a putative endogenous cannabinoid receptor ligand, induces rapid, transient elevation of intracellular free Ca2+ in neuroblastoma x glioma hybrid NG108-15 cells. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8954083 |
| James JS | Marijuana and chocolate. | 1996 | AIDS Treat News | pmid:11363932 |
| Thomas BF et al. | Structure-activity analysis of anandamide analogs: relationship to a cannabinoid pharmacophore. | 1996 | J. Med. Chem. | pmid:8558515 |
| Randall MD et al. | An endogenous cannabinoid as an endothelium-derived vasorelaxant. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8954092 |
| Khanolkar AD et al. | Head group analogs of arachidonylethanolamide, the endogenous cannabinoid ligand. | 1996 | J. Med. Chem. | pmid:8893848 |
| Sugiura T et al. | Transacylase-mediated and phosphodiesterase-mediated synthesis of N-arachidonoylethanolamine, an endogenous cannabinoid-receptor ligand, in rat brain microsomes. Comparison with synthesis from free arachidonic acid and ethanolamine. | 1996 | Eur. J. Biochem. | pmid:8797835 |