Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Berge K et al. | Chronic treatment with krill powder reduces plasma triglyceride and anandamide levels in mildly obese men. | 2013 | Lipids Health Dis | pmid:23706001 |
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Li Q et al. | Anandamide reduces intracellular Ca2+ concentration through suppression of Na+/Ca2+ exchanger current in rat cardiac myocytes. | 2013 | PLoS ONE | pmid:23667607 |
Marco EM et al. | Emotional, endocrine and brain anandamide response to social challenge in infant male rats. | 2013 | Psychoneuroendocrinology | pmid:23660109 |
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Laezza C et al. | Anandamide inhibits the Wnt/β-catenin signalling pathway in human breast cancer MDA MB 231 cells. | 2013 | Eur. J. Cancer | pmid:23434151 |
Kapoor S | Modulation of intracellular pathways by anandamide and its evolving role in oncology. | 2013 | Eur. J. Cancer | pmid:23434147 |
Dudášová A et al. | The effects of cannabidiol on the antigen-induced contraction of airways smooth muscle in the guinea-pig. | 2013 | Pulm Pharmacol Ther | pmid:23428645 |
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Avraham Y et al. | Novel acylethanolamide derivatives that modulate body weight through enhancement of hypothalamic pro-opiomelanocortin (POMC) and/or decreased neuropeptide Y (NPY). | 2013 | J. Med. Chem. | pmid:23384387 |
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Compagnucci C et al. | Type-1 (CB1) cannabinoid receptor promotes neuronal differentiation and maturation of neural stem cells. | 2013 | PLoS ONE | pmid:23372698 |
Gebeh AK et al. | Elevated anandamide and related N-acylethanolamine levels occur in the peripheral blood of women with ectopic pregnancy and are mirrored by changes in peripheral fatty acid amide hydrolase activity. | 2013 | J. Clin. Endocrinol. Metab. | pmid:23372171 |
Li H et al. | Inhibition of fatty acid amide hydrolase activates Nrf2 signalling and induces heme oxygenase 1 transcription in breast cancer cells. | 2013 | Br. J. Pharmacol. | pmid:23347118 |
Zhuang J et al. | The interaction of fatty acid amide hydrolase (FAAH) inhibitors with an anandamide carrier protein using (19)F-NMR. | 2013 | AAPS J | pmid:23344792 |
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Lenglet S et al. | Fatty acid amide hydrolase deficiency enhances intraplaque neutrophil recruitment in atherosclerotic mice. | 2013 | Arterioscler. Thromb. Vasc. Biol. | pmid:23241405 |
Berger WT et al. | Targeting fatty acid binding protein (FABP) anandamide transporters - a novel strategy for development of anti-inflammatory and anti-nociceptive drugs. | 2012 | PLoS ONE | pmid:23236415 |
Silva GB et al. | Anandamide inhibits transport-related oxygen consumption in the loop of Henle by activating CB1 receptors. | 2013 | Am. J. Physiol. Renal Physiol. | pmid:23220721 |
Dékány A et al. | The contractile effect of anandamide in the guinea-pig small intestine is mediated by prostanoids but not TRPV1 receptors or capsaicin-sensitive nerves. | 2013 | Basic Clin. Pharmacol. Toxicol. | pmid:23216932 |
Citraro R et al. | Antiepileptic action of N-palmitoylethanolamine through CB1 and PPAR-α receptor activation in a genetic model of absence epilepsy. | 2013 | Neuropharmacology | pmid:23206503 |
Fogaça MV et al. | Effects of glutamate NMDA and TRPV1 receptor antagonists on the biphasic responses to anandamide injected into the dorsolateral periaqueductal grey of Wistar rats. | 2013 | Psychopharmacology (Berl.) | pmid:23183551 |
Buczynski MW et al. | The volitional nature of nicotine exposure alters anandamide and oleoylethanolamide levels in the ventral tegmental area. | 2013 | Neuropsychopharmacology | pmid:23169348 |
Zohrabi-Kalantari V et al. | 4-Aminocyclopentane-1,3-diols as platforms for diversity: synthesis of anandamide analogs. | 2013 | Med Chem | pmid:23157226 |
Guindon J et al. | Alterations in endocannabinoid tone following chemotherapy-induced peripheral neuropathy: effects of endocannabinoid deactivation inhibitors targeting fatty-acid amide hydrolase and monoacylglycerol lipase in comparison to reference analgesics following cisplatin treatment. | 2013 | Pharmacol. Res. | pmid:23127915 |
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Abán C et al. | Differential expression of endocannabinoid system in normal and preeclamptic placentas: effects on nitric oxide synthesis. | 2013 | Placenta | pmid:23122699 |
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Rani Sagar D et al. | Dynamic changes to the endocannabinoid system in models of chronic pain. | 2012 | Philos. Trans. R. Soc. Lond., B, Biol. Sci. | pmid:23108548 |
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Pedroza-Llinás R et al. | CB1 receptor activation in the nucleus accumbens core impairs contextual fear learning. | 2013 | Behav. Brain Res. | pmid:23018128 |
Butti E et al. | Subventricular zone neural progenitors protect striatal neurons from glutamatergic excitotoxicity. | 2012 | Brain | pmid:23008234 |
Li Q et al. | Anandamide enhances expression of heat shock protein 72 to protect against ischemia-reperfusion injury in rat heart. | 2013 | J Physiol Sci | pmid:23007622 |
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Lee TT et al. | Temporal changes in N-acylethanolamine content and metabolism throughout the peri-adolescent period. | 2013 | Synapse | pmid:22987804 |
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Schreiber AK et al. | Peripheral antinociceptive effect of anandamide and drugs that affect the endocannabinoid system on the formalin test in normal and streptozotocin-diabetic rats. | 2012 | Neuropharmacology | pmid:22959964 |
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Chon SH et al. | Over-expression of monoacylglycerol lipase (MGL) in small intestine alters endocannabinoid levels and whole body energy balance, resulting in obesity. | 2012 | PLoS ONE | pmid:22937137 |
Rogers TJ | The molecular basis for neuroimmune receptor signaling. | 2012 | J Neuroimmune Pharmacol | pmid:22935971 |
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Tanveer R et al. | The endocannabinoid, anandamide, augments Notch-1 signaling in cultured cortical neurons exposed to amyloid-β and in the cortex of aged rats. | 2012 | J. Biol. Chem. | pmid:22891244 |
Chicca A et al. | Evidence for bidirectional endocannabinoid transport across cell membranes. | 2012 | J. Biol. Chem. | pmid:22879589 |
De Petrocellis L et al. | A re-evaluation of 9-HODE activity at TRPV1 channels in comparison with anandamide: enantioselectivity and effects at other TRP channels and in sensory neurons. | 2012 | Br. J. Pharmacol. | pmid:22861649 |
Kaczocha M et al. | Anandamide externally added to lipid vesicles containing trapped fatty acid amide hydrolase (FAAH) is readily hydrolyzed in a sterol-modulated fashion. | 2012 | ACS Chem Neurosci | pmid:22860204 |
Lara-Celador I et al. | Endocannabinoids reduce cerebral damage after hypoxic-ischemic injury in perinatal rats. | 2012 | Brain Res. | pmid:22841538 |
Leweke FM et al. | Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia. | 2012 | Transl Psychiatry | pmid:22832859 |
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Moreno-Sanz G et al. | Pharmacological characterization of the peripheral FAAH inhibitor URB937 in female rodents: interaction with the Abcg2 transporter in the blood-placenta barrier. | 2012 | Br. J. Pharmacol. | pmid:22774772 |