Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Smart D et al. | The endogenous lipid anandamide is a full agonist at the human vanilloid receptor (hVR1). | 2000 | Br. J. Pharmacol. | pmid:10694225 |
Burstein SH et al. | Oxidative metabolism of anandamide. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10785540 |
Di Marzo V et al. | Cannabimimetic fatty acid derivatives in cancer and inflammation. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10785541 |
Kunos G et al. | Cardiovascular effects of endocannabinoids--the plot thickens. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10785543 |
Maccarrone M et al. | Anandamide uptake by human endothelial cells and its regulation by nitric oxide. | 2000 | J. Biol. Chem. | pmid:10788462 |
Yagen B and Burstein S | Novel and sensitive method for the detection of anandamide by the use of its dansyl derivative. | 2000 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:10798298 |
Rajan S et al. | TASK-3, a novel tandem pore domain acid-sensitive K+ channel. An extracellular histiding as pH sensor. | 2000 | J. Biol. Chem. | pmid:10747866 |
Stefano GB et al. | 2-arachidonyl-glycerol stimulates nitric oxide release from human immune and vascular tissues and invertebrate immunocytes by cannabinoid receptor 1. | 2000 | Pharmacol. Res. | pmid:10987990 |
Okamoto H et al. | Sphingosine 1-phosphate stimulates G(i)- and Rho-mediated vascular endothelial cell spreading and migration. | 2000 | Thromb. Res. | pmid:10942792 |
Stefano GB | Endocannabinoid immune and vascular signaling. | 2000 | Acta Pharmacol. Sin. | pmid:11603279 |
Martin BR et al. | Cannabinoid properties of methylfluorophosphonate analogs. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10945879 |
Harris J et al. | Spinal anandamide inhibits nociceptive transmission via cannabinoid receptor activation in vivo. | 2000 | Neuroreport | pmid:10976969 |
Oz M et al. | Endogenous cannabinoid anandamide directly inhibits voltage-dependent Ca(2+) fluxes in rabbit T-tubule membranes. | 2000 | Eur. J. Pharmacol. | pmid:10980258 |
Klein TW et al. | The cannabinoid system and cytokine network. | 2000 | Proc. Soc. Exp. Biol. Med. | pmid:10998193 |
Oliveira L et al. | Effects of some isoprostanes on the human umbilical artery in vitro. | 2000 | Br. J. Pharmacol. | pmid:10711349 |
Hansen HH et al. | Determination of the phospholipid precursor of anandamide and other N-acylethanolamine phospholipids before and after sodium azide-induced toxicity in cultured neocortical neurons. | 2000 | J. Neurochem. | pmid:10899965 |
Maccarrone M et al. | Human mast cells take up and hydrolyze anandamide under the control of 5-lipoxygenase and do not express cannabinoid receptors. | 2000 | FEBS Lett. | pmid:10692582 |
Premkumar LS and Ahern GP | Induction of vanilloid receptor channel activity by protein kinase C. | 2000 Dec 21-28 | Nature | pmid:11140687 |
Hungund BL and Basavarajappa BS | Are anandamide and cannabinoid receptors involved in ethanol tolerance? A review of the evidence. | 2000 Mar-Apr | Alcohol Alcohol. | pmid:10787386 |
Grainger J and Boachie-Ansah G | Anandamide-induced relaxation of sheep coronary arteries: the role of the vascular endothelium, arachidonic acid metabolites and potassium channels. | 2001 | Br. J. Pharmacol. | pmid:11682448 |
Farquhar-Smith WP and Rice AS | Administration of endocannabinoids prevents a referred hyperalgesia associated with inflammation of the urinary bladder. | 2001 | Anesthesiology | pmid:11374613 |
Ralevic V et al. | Cannabinoid activation of recombinant and endogenous vanilloid receptors. | 2001 | Eur. J. Pharmacol. | pmid:11672565 |
Christopoulos A and Wilson K | Interaction of anandamide with the M(1) and M(4) muscarinic acetylcholine receptors. | 2001 | Brain Res. | pmid:11578621 |
White R et al. | Mechanisms of anandamide-induced vasorelaxation in rat isolated coronary arteries. | 2001 | Br. J. Pharmacol. | pmid:11606334 |
Fowler CJ et al. | Fatty acid amide hydrolase: biochemistry, pharmacology, and therapeutic possibilities for an enzyme hydrolyzing anandamide, 2-arachidonoylglycerol, palmitoylethanolamide, and oleamide. | 2001 | Biochem. Pharmacol. | pmid:11585048 |
Mendizábal VE et al. | Long-term inhibition of nitric oxide synthase potentiates effects of anandamide in the rat mesenteric bed. | 2001 | Eur. J. Pharmacol. | pmid:11567656 |
Izzo AA et al. | Effect of vanilloid drugs on gastrointestinal transit in mice. | 2001 | Br. J. Pharmacol. | pmid:11264233 |
Baker D et al. | Endocannabinoids control spasticity in a multiple sclerosis model. | 2001 | FASEB J. | pmid:11156943 |
Gauldie SD et al. | Anandamide activates peripheral nociceptors in normal and arthritic rat knee joints. | 2001 | Br. J. Pharmacol. | pmid:11159713 |
Tognetto M et al. | Anandamide excites central terminals of dorsal root ganglion neurons via vanilloid receptor-1 activation. | 2001 | J. Neurosci. | pmid:11160380 |
MacCarrone M et al. | Human platelets bind and degrade 2-arachidonoylglycerol, which activates these cells through a cannabinoid receptor. | 2001 | Eur. J. Biochem. | pmid:11168423 |
Senior K | Endogenously produced cannabinoids and liver cirrhosis. | 2001 | Lancet | pmid:11454385 |
Stanford SJ et al. | Identification of two distinct vasodilator pathways activated by ATP in the mesenteric bed of the rat. | 2001 | Br. J. Pharmacol. | pmid:11454655 |
Mang CF et al. | Differential effects of anandamide on acetylcholine release in the guinea-pig ileum mediated via vanilloid and non-CB1 cannabinoid receptors. | 2001 | Br. J. Pharmacol. | pmid:11522608 |
Bradbury J | Small part of cannabis puzzle solved by animal studies. | 2001 | Lancet | pmid:11498223 |
Jonsson KO et al. | Effects of homologues and analogues of palmitoylethanolamide upon the inactivation of the endocannabinoid anandamide. | 2001 | Br. J. Pharmacol. | pmid:11498512 |
Hayase T et al. | Protective effects of cannabinoid receptor ligands analogous to anandamide against cocaine toxicity. | 2001 | Nihon Arukoru Yakubutsu Igakkai Zasshi | pmid:11828716 |
Deutsch DG et al. | The cellular uptake of anandamide is coupled to its breakdown by fatty-acid amide hydrolase. | 2001 | J. Biol. Chem. | pmid:11118429 |
Mechoulam R and Fride E | Physiology. A hunger for cannabinoids. | 2001 | Nature | pmid:11298428 |
Smart D et al. | Characterisation using FLIPR of human vanilloid VR1 receptor pharmacology. | 2001 | Eur. J. Pharmacol. | pmid:11301059 |
Bueb JL et al. | Receptor-independent effects of natural cannabinoids in rat peritoneal mast cells in vitro. | 2001 | Biochim. Biophys. Acta | pmid:11336796 |
Kim D and Thayer SA | Cannabinoids inhibit the formation of new synapses between hippocampal neurons in culture. | 2001 | J. Neurosci. | pmid:11319244 |
Kagota S et al. | 2-Arachidonoylglycerol, a candidate of endothelium-derived hyperpolarizing factor. | 2001 | Eur. J. Pharmacol. | pmid:11275004 |
Bisogno T et al. | The uptake by cells of 2-arachidonoylglycerol, an endogenous agonist of cannabinoid receptors. | 2001 | Eur. J. Biochem. | pmid:11277920 |
De Petrocellis L et al. | The activity of anandamide at vanilloid VR1 receptors requires facilitated transport across the cell membrane and is limited by intracellular metabolism. | 2001 | J. Biol. Chem. | pmid:11278420 |
Jacobsson SO and Fowler CJ | Characterization of palmitoylethanolamide transport in mouse Neuro-2a neuroblastoma and rat RBL-2H3 basophilic leukaemia cells: comparison with anandamide. | 2001 | Br. J. Pharmacol. | pmid:11309246 |
Quistad GB et al. | Fatty acid amide hydrolase inhibition by neurotoxic organophosphorus pesticides. | 2001 | Toxicol. Appl. Pharmacol. | pmid:11350214 |
Möhle R et al. | Transendothelial migration of hematopoietic progenitor cells. Role of chemotactic factors. | 2001 | Ann. N. Y. Acad. Sci. | pmid:11458515 |
Wenger T et al. | The central cannabinoid receptor inactivation suppresses endocrine reproductive functions. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11394887 |
Maccarrone M et al. | Gas chromatography-mass spectrometry analysis of endogenous cannabinoids in healthy and tumoral human brain and human cells in culture. | 2001 | J. Neurochem. | pmid:11208922 |