Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Anandamide
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Ferreira SG et al. | N-acyldopamines control striatal input terminals via novel ligand-gated cation channels. | 2009 | Neuropharmacology | pmid:19101577 |
Acone G et al. | Low type I cannabinoid receptor levels characterize placental villous in labouring delivery. | 2009 | Placenta | pmid:19097644 |
Wheal AJ and Randall MD | Effects of hypertension on vasorelaxation to endocannabinoids in vitro. | 2009 | Eur. J. Pharmacol. | pmid:19100733 |
EscartÃn-Pérez RE et al. | Role of cannabinoid CB1 receptors on macronutrient selection and satiety in rats. | 2009 | Physiol. Behav. | pmid:19150453 |
Ozalp A and Barroso B | Simultaneous quantitative analysis of N-acylethanolamides in clinical samples. | 2009 | Anal. Biochem. | pmid:19665986 |
Eckardt K et al. | Cannabinoid type 1 receptors in human skeletal muscle cells participate in the negative crosstalk between fat and muscle. | 2009 | Diabetologia | pmid:19089403 |
Karbarz MJ et al. | Biochemical and biological properties of 4-(3-phenyl-[1,2,4] thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide, a mechanism-based inhibitor of fatty acid amide hydrolase. | 2009 | Anesth. Analg. | pmid:19095868 |
Vignali M et al. | The endocannabinoid anandamide inhibits potassium conductance in rat cortical astrocytes. | 2009 | Glia | pmid:19031444 |
Fernandez-Solari J et al. | Anandamide injected into the lateral ventricle of the brain inhibits submandibular salivary secretion by attenuating parasympathetic neurotransmission. | 2009 | Braz. J. Med. Biol. Res. | pmid:19448903 |
Ribeiro A et al. | Dose-response effects of systemic anandamide administration in mice sequentially submitted to the open field and elevated plus-maze tests. | 2009 | Braz. J. Med. Biol. Res. | pmid:19448906 |
Li D et al. | Role of anandamide transporter in regulating calcitonin gene-related peptide production and blood pressure in hypertension. | 2009 | J. Hypertens. | pmid:19462497 |
Mahmud A et al. | Cannabinoid 1 receptor activation inhibits transient receptor potential vanilloid type 1 receptor-mediated cationic influx into rat cultured primary sensory neurons. | 2009 | Neuroscience | pmid:19463903 |
Vann RE et al. | Discriminative stimulus properties of delta9-tetrahydrocannabinol (THC) in C57Bl/6J mice. | 2009 | Eur. J. Pharmacol. | pmid:19470387 |
Vercelli CA et al. | Anandamide regulates lipopolysaccharide-induced nitric oxide synthesis and tissue damage in the murine uterus. | 2009 | Reprod. Biomed. Online | pmid:19490788 |
Aquila S et al. | A new role of anandamide in human sperm: focus on metabolism. | 2009 | J. Cell. Physiol. | pmid:19492411 |
Kingsley PJ and Marnett LJ | Analysis of endocannabinoids, their congeners and COX-2 metabolites. | 2009 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:19505857 |
Dowie MJ et al. | Altered CB1 receptor and endocannabinoid levels precede motor symptom onset in a transgenic mouse model of Huntington's disease. | 2009 | Neuroscience | pmid:19524019 |
Wise LE et al. | Fatty acid amide hydrolase (FAAH) knockout mice exhibit enhanced acquisition of an aversive, but not of an appetitive, Barnes maze task. | 2009 | Neurobiol Learn Mem | pmid:19524055 |
Maeda N et al. | Increased serum anandamide level at ruptured plaque site in patients with acute myocardial infarction. | 2009 | Fundam Clin Pharmacol | pmid:19527302 |
Straiker A and Mackie K | Cannabinoid signaling in inhibitory autaptic hippocampal neurons. | 2009 | Neuroscience | pmid:19501632 |
Kinsey SG et al. | Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain. | 2009 | J. Pharmacol. Exp. Ther. | pmid:19502530 |
Grimaldi P et al. | The endocannabinoid system and pivotal role of the CB2 receptor in mouse spermatogenesis. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19541620 |
Grider JR et al. | Modulation of motor and sensory pathways of the peristaltic reflex by cannabinoids. | 2009 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:19589944 |
Batetta B et al. | Endocannabinoids may mediate the ability of (n-3) fatty acids to reduce ectopic fat and inflammatory mediators in obese Zucker rats. | 2009 | J. Nutr. | pmid:19549757 |
Catanzaro G et al. | Anandamide increases swelling and reduces calcium sensitivity of mitochondria. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19679102 |
Fraga D et al. | Endogenous cannabinoids induce fever through the activation of CB1 receptors. | 2009 | Br. J. Pharmacol. | pmid:19681872 |
Lozovaya N et al. | Dual modulation of CNS voltage-gated calcium channels by cannabinoids: Focus on CB1 receptor-independent effects. | 2009 | Cell Calcium | pmid:19682741 |
Okamoto Y et al. | Enzymatic formation of anandamide. | 2009 | Vitam. Horm. | pmid:19647106 |
Yates ML and Barker EL | Organized trafficking of anandamide and related lipids. | 2009 | Vitam. Horm. | pmid:19647107 |
Goodfellow CE and Glass M | Anandamide receptor signal transduction. | 2009 | Vitam. Horm. | pmid:19647109 |
Brown AJ and Robin Hiley C | Is GPR55 an anandamide receptor? | 2009 | Vitam. Horm. | pmid:19647110 |
Correa FG et al. | The endocannabinoid anandamide from immunomodulation to neuroprotection. Implications for multiple sclerosis. | 2009 | Vitam. Horm. | pmid:19647114 |
Tóth A et al. | Anandamide and the vanilloid receptor (TRPV1). | 2009 | Vitam. Horm. | pmid:19647120 |
Pasquariello N et al. | Regulation of gene transcription and keratinocyte differentiation by anandamide. | 2009 | Vitam. Horm. | pmid:19647122 |
Alpini G and Demorrow S | Changes in the endocannabinoid system may give insight into new and effective treatments for cancer. | 2009 | Vitam. Horm. | pmid:19647123 |
Astarita G et al. | Targeted lipidomics as a tool to investigate endocannabinoid function. | 2009 | Int. Rev. Neurobiol. | pmid:19607960 |
Francavilla F et al. | Characterization of the endocannabinoid system in human spermatozoa and involvement of transient receptor potential vanilloid 1 receptor in their fertilizing ability. | 2009 | Endocrinology | pmid:19608651 |
Centonze D et al. | Altered anandamide degradation in attention-deficit/hyperactivity disorder. | 2009 | Neurology | pmid:19398708 |
Liu H et al. | Endocannabinoids anandamide and its cannabinoid receptors in liver fibrosis after murine schistosomiasis. | 2009 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:19399401 |
Di Pasquale E et al. | The insertion and transport of anandamide in synthetic lipid membranes are both cholesterol-dependent. | 2009 | PLoS ONE | pmid:19330032 |
Balas L et al. | Total synthesis of photoactivatable or fluorescent anandamide probes: novel bioactive compounds with angiogenic activity. | 2009 | J. Med. Chem. | pmid:19161308 |
Pelorosso FG et al. | The endocannabinoid anandamide inhibits kinin B1 receptor sensitization through cannabinoid CB1 receptor stimulation in human umbilical vein. | 2009 | Eur. J. Pharmacol. | pmid:19022239 |
Guindon J and Hohmann AG | The endocannabinoid system and pain. | 2009 | CNS Neurol Disord Drug Targets | pmid:19839937 |
Vercelli CA et al. | Endocannabinoid system and nitric oxide are involved in the deleterious effects of lipopolysaccharide on murine decidua. | 2009 | Placenta | pmid:19428101 |
Li Q et al. | Electrophysiological effects of anandamide on rat myocardium. | 2009 | Br. J. Pharmacol. | pmid:20050190 |
Järbe TU et al. | Discriminative stimulus functions in rats of AM1346, a high-affinity CB1R selective anandamide analog. | 2009 | Psychopharmacology (Berl.) | pmid:18521574 |
Hiley CR | Endocannabinoids and the heart. | 2009 | J. Cardiovasc. Pharmacol. | pmid:19276990 |
Gratzke C et al. | Distribution and function of cannabinoid receptors 1 and 2 in the rat, monkey and human bladder. | 2009 | J. Urol. | pmid:19237169 |
El-Talatini MR et al. | Localisation and function of the endocannabinoid system in the human ovary. | 2009 | PLoS ONE | pmid:19238202 |
Sun X et al. | Genetic loss of Faah compromises male fertility in mice. | 2009 | Biol. Reprod. | pmid:18987328 |
Marczylo TH et al. | A solid-phase method for the extraction and measurement of anandamide from multiple human biomatrices. | 2009 | Anal. Biochem. | pmid:18823934 |
Long JZ et al. | Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19918051 |
Hong S et al. | Reciprocal changes in vanilloid (TRPV1) and endocannabinoid (CB1) receptors contribute to visceral hyperalgesia in the water avoidance stressed rat. | 2009 | Gut | pmid:18936104 |
Correa F et al. | A role for CB2 receptors in anandamide signalling pathways involved in the regulation of IL-12 and IL-23 in microglial cells. | 2009 | Biochem. Pharmacol. | pmid:18848818 |
McCue JM et al. | In vitro synthesis of arachidonoyl amino acids by cytochrome c. | 2009 | Prostaglandins Other Lipid Mediat. | pmid:19683594 |
Cottone E et al. | Goldfish CB1 mRNA expression is affected by fasting and anandamide administration. | 2009 | Neuroreport | pmid:19293731 |
Villanueva A et al. | Central cannabinoid 1 receptor antagonist administration prevents endotoxic hypotension affecting norepinephrine release in the preoptic anterior hypothalamic area. | 2009 | Shock | pmid:19295473 |
Izzo AA et al. | Peripheral endocannabinoid dysregulation in obesity: relation to intestinal motility and energy processing induced by food deprivation and re-feeding. | 2009 | Br. J. Pharmacol. | pmid:19371345 |
Appendino G et al. | Conformationally constrained fatty acid ethanolamides as cannabinoid and vanilloid receptor probes. | 2009 | J. Med. Chem. | pmid:19361197 |
El-Talatini MR et al. | Fluctuation in anandamide levels from ovulation to early pregnancy in in-vitro fertilization-embryo transfer women, and its hormonal regulation. | 2009 | Hum. Reprod. | pmid:19363040 |
Clapper JR et al. | The endocannabinoid system as a target for the treatment of cannabis dependence. | 2009 | Neuropharmacology | pmid:18691603 |
Brizzi A et al. | New resorcinol-anandamide "hybrids" as potent cannabinoid receptor ligands endowed with antinociceptive activity in vivo. | 2009 | J. Med. Chem. | pmid:19331413 |
Koethe D et al. | Anandamide elevation in cerebrospinal fluid in initial prodromal states of psychosis. | 2009 | Br J Psychiatry | pmid:19336792 |
Mangieri RA et al. | An endocannabinoid signal associated with desire for alcohol is suppressed in recently abstinent alcoholics. | 2009 | Psychopharmacology (Berl.) | pmid:19343330 |
Potenzieri C et al. | Excitation of cutaneous C nociceptors by intraplantar administration of anandamide. | 2009 | Brain Res. | pmid:19285051 |
De Petrocellis L and Di Marzo V | An introduction to the endocannabinoid system: from the early to the latest concepts. | 2009 | Best Pract. Res. Clin. Endocrinol. Metab. | pmid:19285257 |
Catani MV et al. | Expression of the endocannabinoid system in the bi-potential HEL cell line: commitment to the megakaryoblastic lineage by 2-arachidonoylglycerol. | 2009 | J. Mol. Med. | pmid:18820887 |
Shinohara Y et al. | Cannabinoid in the nucleus accumbens enhances the intake of palatable solution. | 2009 | Neuroreport | pmid:19734811 |
Campos AC and Guimarães FS | Evidence for a potential role for TRPV1 receptors in the dorsolateral periaqueductal gray in the attenuation of the anxiolytic effects of cannabinoids. | 2009 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:19735690 |
Wyffels L et al. | Synthesis, in vitro and in vivo evaluation, and radiolabeling of aryl anandamide analogues as candidate radioligands for in vivo imaging of fatty acid amide hydrolase in the brain. | 2009 | J. Med. Chem. | pmid:19719235 |
Di Marzo V et al. | Role of insulin as a negative regulator of plasma endocannabinoid levels in obese and nonobese subjects. | 2009 | Eur. J. Endocrinol. | pmid:19745037 |
Cano C et al. | Synthesis and pharmacological evaluation of sulfamide-based analogues of anandamide. | 2009 | Eur J Med Chem | pmid:19762126 |
Centonze D et al. | Lack of effect of cannabis-based treatment on clinical and laboratory measures in multiple sclerosis. | 2009 | Neurol. Sci. | pmid:19768368 |
Jean-Gilles L et al. | Plasma endocannabinoid levels in multiple sclerosis. | 2009 | J. Neurol. Sci. | pmid:19695579 |
Wyffels L et al. | Radiosynthesis, in vitro and in vivo evaluation of 123I-labeled anandamide analogues for mapping brain FAAH. | 2009 | Bioorg. Med. Chem. | pmid:19054678 |
Rossi F et al. | The endovanilloid/endocannabinoid system in human osteoclasts: possible involvement in bone formation and resorption. | 2009 | Bone | pmid:19059369 |
Jiang LS et al. | Role of activated endocannabinoid system in regulation of cellular cholesterol metabolism in macrophages. | 2009 | Cardiovasc. Res. | pmid:19074161 |
Aneetha H et al. | Alcohol dehydrogenase-catalyzed in vitro oxidation of anandamide to N-arachidonoyl glycine, a lipid mediator: synthesis of N-acyl glycinals. | 2009 | Bioorg. Med. Chem. Lett. | pmid:19013794 |
Panlilio LV et al. | Anandamide-induced behavioral disruption through a vanilloid-dependent mechanism in rats. | 2009 | Psychopharmacology (Berl.) | pmid:19015836 |
De Petrocellis L et al. | Chemical synthesis, pharmacological characterization, and possible formation in unicellular fungi of 3-hydroxy-anandamide. | 2009 | J. Lipid Res. | pmid:19017617 |
Tuboly G et al. | Antinociceptive interactions between anandamide and endomorphin-1 at the spinal level. | 2009 | Clin. Exp. Pharmacol. Physiol. | pmid:19018802 |
Schacht JP et al. | Intermediate cannabis dependence phenotypes and the FAAH C385A variant: an exploratory analysis. | 2009 | Psychopharmacology (Berl.) | pmid:19002671 |
Mato S et al. | CB1 cannabinoid receptor-dependent and -independent inhibition of depolarization-induced calcium influx in oligodendrocytes. | 2009 | Glia | pmid:18814177 |
Araújo JR et al. | Effect of cannabinoids upon the uptake of folic acid by BeWo cells. | 2009 | Pharmacology | pmid:19145103 |
Kurjak M et al. | Differential stimulatory effects of cannabinoids on VIP release and NO synthase activity in synaptosomal fractions from rat ileum. | 2008 Oct-Dec | Neuropeptides | pmid:18829105 |
Lissoni P et al. | The endocannabinoid anandamide neither impairs in vitro T-cell function nor induces regulatory T-cell generation. | 2008 Nov-Dec | Anticancer Res. | pmid:19189659 |
Sakamoto Y et al. | Effectiveness of continuous hemodiafiltration using a polymethylmethacrylate membrane hemofilter after polymyxin B-immobilized fiber column therapy of septic shock. | 2008 Jan-Feb | ASAIO J. | pmid:18204329 |
Lam PM et al. | Ultra performance liquid chromatography tandem mass spectrometry method for the measurement of anandamide in human plasma. | 2008 | Anal. Biochem. | pmid:18555789 |
Horvath G et al. | The role of TRPV1 receptors in the antinociceptive effect of anandamide at spinal level. | 2008 | Pain | pmid:17533116 |
Zolese G et al. | Effect of acylethanolamides on lipid peroxidation and paraoxonase activity. | 2008 | Biofactors | pmid:19478424 |
Liu J et al. | Multiple pathways involved in the biosynthesis of anandamide. | 2008 | Neuropharmacology | pmid:17631919 |
Starowicz KM et al. | Endocannabinoid dysregulation in the pancreas and adipose tissue of mice fed with a high-fat diet. | 2008 | Obesity (Silver Spring) | pmid:18239598 |
McFarland MJ et al. | RNA interference-mediated knockdown of dynamin 2 reduces endocannabinoid uptake into neuronal dCAD cells. | 2008 | Mol. Pharmacol. | pmid:18436710 |
Nomura DK et al. | Activation of the endocannabinoid system by organophosphorus nerve agents. | 2008 | Nat. Chem. Biol. | pmid:18438404 |
Palmer JA et al. | Fatty acid amide hydrolase inhibition enhances the anti-allodynic actions of endocannabinoids in a model of acute pain adapted for the mouse. | 2008 | Neuroscience | pmid:18541380 |
Habayeb OM et al. | Expression of the endocannabinoid system in human first trimester placenta and its role in trophoblast proliferation. | 2008 | Endocrinology | pmid:18599552 |
Waldeck-Weiermair M et al. | Integrin clustering enables anandamide-induced Ca2+ signaling in endothelial cells via GPR55 by protection against CB1-receptor-triggered repression. | 2008 | J. Cell. Sci. | pmid:18445684 |
Resstel LB et al. | Activation of CB1 cannabinoid receptors in the dorsolateral periaqueductal gray reduces the expression of contextual fear conditioning in rats. | 2008 | Psychopharmacology (Berl.) | pmid:18446325 |
Cella M et al. | Dual effect of anandamide on rat placenta nitric oxide synthesis. | 2008 | Placenta | pmid:18561998 |
Placzek EA et al. | Membrane microdomains and metabolic pathways that define anandamide and 2-arachidonyl glycerol biosynthesis and breakdown. | 2008 | Neuropharmacology | pmid:18760289 |