Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Breast Neoplasms D001943 24 associated lipids
Neoplasms D009369 13 associated lipids
Pain D010146 64 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Fatty Liver D005234 48 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Hypotension D007022 41 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Melanoma D008545 69 associated lipids
Weight Gain D015430 101 associated lipids
Hyperemia D006940 25 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Glioma D005910 112 associated lipids
Obesity D009765 29 associated lipids
Bradycardia D001919 13 associated lipids
Urinary Bladder Diseases D001745 4 associated lipids
Alzheimer Disease D000544 76 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Neuroblastoma D009447 66 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Multiple Sclerosis D009103 13 associated lipids
Nervous System Diseases D009422 37 associated lipids
Ataxia D001259 20 associated lipids
Brain Edema D001929 20 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Brain Ischemia D002545 89 associated lipids
Epilepsy D004827 35 associated lipids
Seizures D012640 87 associated lipids
Nerve Degeneration D009410 53 associated lipids
Peptic Ulcer D010437 19 associated lipids
Hypertension D006973 115 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Substance-Related Disorders D019966 2 associated lipids
Hepatitis D006505 11 associated lipids
Hyperalgesia D006930 42 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Brain Damage, Chronic D001925 6 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Grainger J and Boachie-Ansah G Anandamide-induced relaxation of sheep coronary arteries: the role of the vascular endothelium, arachidonic acid metabolites and potassium channels. 2001 Br. J. Pharmacol. pmid:11682448
Farquhar-Smith WP and Rice AS Administration of endocannabinoids prevents a referred hyperalgesia associated with inflammation of the urinary bladder. 2001 Anesthesiology pmid:11374613
White R et al. Mechanisms of anandamide-induced vasorelaxation in rat isolated coronary arteries. 2001 Br. J. Pharmacol. pmid:11606334
Maingret F et al. The endocannabinoid anandamide is a direct and selective blocker of the background K(+) channel TASK-1. 2001 EMBO J. pmid:11226154
Boger DL et al. alpha-Keto heterocycle inhibitors of fatty acid amide hydrolase: carbonyl group modification and alpha-substitution. 2001 Bioorg. Med. Chem. Lett. pmid:11412972
Tognetto M et al. Anandamide excites central terminals of dorsal root ganglion neurons via vanilloid receptor-1 activation. 2001 J. Neurosci. pmid:11160380
MacCarrone M et al. Human platelets bind and degrade 2-arachidonoylglycerol, which activates these cells through a cannabinoid receptor. 2001 Eur. J. Biochem. pmid:11168423
Hansen HH et al. Accumulation of the anandamide precursor and other N-acylethanolamine phospholipids in infant rat models of in vivo necrotic and apoptotic neuronal death. 2001 J. Neurochem. pmid:11145976
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Nogueron MI et al. Cannabinoid receptor agonists inhibit depolarization-induced calcium influx in cerebellar granule neurons. 2001 J. Neurochem. pmid:11677265
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Jamshidi N and Taylor DA Anandamide administration into the ventromedial hypothalamus stimulates appetite in rats. 2001 Br. J. Pharmacol. pmid:11704633
Gurwitz D and Weizman A Fatty acid amide hydrolase inhibitors and the marijuana debate. 2001 Lancet pmid:11705595
Rice AS Cannabinoids and pain. 2001 Curr Opin Investig Drugs pmid:11575713
Karava V et al. Anandamide amidohydrolase activity, released in the medium by Tetrahymena pyriformis. Identification and partial characterization. 2001 FEBS Lett. pmid:11728445
Stamer WD et al. Cannabinoid CB(1) receptor expression, activation and detection of endogenous ligand in trabecular meshwork and ciliary process tissues. 2001 Eur. J. Pharmacol. pmid:11730719
Hayase T et al. Protective effects of cannabinoid receptor agonists against cocaine and other convulsant-induced toxic behavioural symptoms. 2001 J. Pharm. Pharmacol. pmid:11732755
Hansen HH et al. Anandamide, but not 2-arachidonoylglycerol, accumulates during in vivo neurodegeneration. 2001 J. Neurochem. pmid:11579150
Smith PJ and McQueen DS Anandamide induces cardiovascular and respiratory reflexes via vasosensory nerves in the anaesthetized rat. 2001 Br. J. Pharmacol. pmid:11588121
Maccarrone M et al. Lipopolysaccharide downregulates fatty acid amide hydrolase expression and increases anandamide levels in human peripheral lymphocytes. 2001 Arch. Biochem. Biophys. pmid:11556820
Crozier Willi G et al. Lipids in neural function: modulation of behavior by oral administration of endocannabinoids found in foods. 2001 Nestle Nutr Workshop Ser Clin Perform Programme pmid:11510437
Craib SJ et al. A possible role of lipoxygenase in the activation of vanilloid receptors by anandamide in the guinea-pig bronchus. 2001 Br. J. Pharmacol. pmid:11522594
Deutsch DG et al. The cellular uptake of anandamide is coupled to its breakdown by fatty-acid amide hydrolase. 2001 J. Biol. Chem. pmid:11118429
Al-Hayani A et al. The endogenous cannabinoid anandamide activates vanilloid receptors in the rat hippocampal slice. 2001 Neuropharmacology pmid:11747904
Izzo AA et al. The gastrointestinal pharmacology of cannabinoids. 2001 Curr Opin Pharmacol pmid:11757815
Wagner JA et al. Endogenous cannabinoids mediate hypotension after experimental myocardial infarction. 2001 J. Am. Coll. Cardiol. pmid:11738314
López-Rodríguez ML et al. Design, synthesis and biological evaluation of novel arachidonic acid derivatives as highly potent and selective endocannabinoid transporter inhibitors. 2001 J. Med. Chem. pmid:11741470
Chemin J et al. Direct inhibition of T-type calcium channels by the endogenous cannabinoid anandamide. 2001 EMBO J. pmid:11742980
Quistad GB et al. Fatty acid amide hydrolase inhibition by neurotoxic organophosphorus pesticides. 2001 Toxicol. Appl. Pharmacol. pmid:11350214
Day TA et al. Role of fatty acid amide hydrolase in the transport of the endogenous cannabinoid anandamide. 2001 Mol. Pharmacol. pmid:11353795
Kobayashi Y et al. Activation by 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, of p42/44 mitogen-activated protein kinase in HL-60 cells. 2001 J. Biochem. pmid:11328586
Chang YH et al. Effects of cannabinoids on LPS-stimulated inflammatory mediator release from macrophages: involvement of eicosanoids. 2001 J. Cell. Biochem. pmid:11329626
Olah Z et al. Anandamide activates vanilloid receptor 1 (VR1) at acidic pH in dorsal root ganglia neurons and cells ectopically expressing VR1. 2001 J. Biol. Chem. pmid:11333266
Calignano A et al. Antinociceptive activity of the endogenous fatty acid amide, palmitylethanolamide. 2001 Eur. J. Pharmacol. pmid:11426841
Di Marzo V et al. Highly selective CB(1) cannabinoid receptor ligands and novel CB(1)/VR(1) vanilloid receptor "hybrid" ligands. 2001 Biochem. Biophys. Res. Commun. pmid:11181068
Fride E et al. Critical role of the endogenous cannabinoid system in mouse pup suckling and growth. 2001 Eur. J. Pharmacol. pmid:11426843
Ugdyzhekova DS et al. Endogenous cannabinoid anandamide increases heart resistance to arrhythmogenic effects of epinephrine: role of CB(1) and CB(2) receptors. 2001 Bull. Exp. Biol. Med. pmid:11427912
Di Marzo V et al. Hypolocomotor effects in rats of capsaicin and two long chain capsaicin homologues. 2001 Eur. J. Pharmacol. pmid:11408034
Breivogel CS et al. Evidence for a new G protein-coupled cannabinoid receptor in mouse brain. 2001 Mol. Pharmacol. pmid:11408610
Wang Y et al. Simultaneous measurement of anandamide and 2-arachidonoylglycerol by polymyxin B-selective adsorption and subsequent high-performance liquid chromatography analysis: increase in endogenous cannabinoids in the sera of patients with endotoxic shock. 2001 Anal. Biochem. pmid:11412008
De Petrocellis L et al. The vanilloid receptor (VR1)-mediated effects of anandamide are potently enhanced by the cAMP-dependent protein kinase. 2001 J. Neurochem. pmid:11413249
Morisset V and Urban L Cannabinoid-induced presynaptic inhibition of glutamatergic EPSCs in substantia gelatinosa neurons of the rat spinal cord. 2001 J. Neurophysiol. pmid:11431486
Bátkai S et al. Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis. 2001 Nat. Med. pmid:11433348
Maccarrone M et al. Progesterone up-regulates anandamide hydrolase in human lymphocytes: role of cytokines and implications for fertility. 2001 J. Immunol. pmid:11390466
Wenger T et al. The central cannabinoid receptor inactivation suppresses endocrine reproductive functions. 2001 Biochem. Biophys. Res. Commun. pmid:11394887
Maccarrone M et al. Gas chromatography-mass spectrometry analysis of endogenous cannabinoids in healthy and tumoral human brain and human cells in culture. 2001 J. Neurochem. pmid:11208922
Di Marzo V et al. Anandamide: some like it hot. 2001 Trends Pharmacol. Sci. pmid:11431028
Ueda N et al. Alkaline and acid amidases hydrolyzing anandamide and other N-acylethanolamines. 2001 World Rev Nutr Diet pmid:11935959