| MeSH term | MeSH ID | Detail |
|---|---|---|
| Stomach Ulcer | D013276 | 75 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Neoplasms | D009369 | 13 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Sagan S et al. | Anandamide and WIN 55212-2 inhibit cyclic AMP formation through G-protein-coupled receptors distinct from CB1 cannabinoid receptors in cultured astrocytes. | 1999 | Eur. J. Neurosci. | pmid:10051770 |
| Lang W et al. | Substrate specificity and stereoselectivity of rat brain microsomal anandamide amidohydrolase. | 1999 | J. Med. Chem. | pmid:10072686 |
| Kobayashi H et al. | Recent progress in the neurotoxicology of natural drugs associated with dependence or addiction, their endogenous agonists and receptors. | 1999 | J Toxicol Sci | pmid:10073332 |
| Bisogno T et al. | Brain regional distribution of endocannabinoids: implications for their biosynthesis and biological function. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10079192 |
| Hohmann AG et al. | Pre- and postsynaptic distribution of cannabinoid and mu opioid receptors in rat spinal cord. | 1999 | Brain Res. | pmid:10082879 |
| Wang J et al. | Stage-specific excitation of cannabinoid receptor exhibits differential effects on mouse embryonic development. | 1999 | Biol. Reprod. | pmid:10084956 |
| Ishioka N and Bukoski RD | A role for N-arachidonylethanolamine (anandamide) as the mediator of sensory nerve-dependent Ca2+-induced relaxation. | 1999 | J. Pharmacol. Exp. Ther. | pmid:10087011 |
| Fleming I et al. | Inhibition of the production of endothelium-derived hyperpolarizing factor by cannabinoid receptor agonists. | 1999 | Br. J. Pharmacol. | pmid:10193775 |
| Self DW | Anandamide: a candidate neurotransmitter heads for the big leagues. | 1999 | Nat. Neurosci. | pmid:10204533 |
| Giuffrida A et al. | Dopamine activation of endogenous cannabinoid signaling in dorsal striatum. | 1999 | Nat. Neurosci. | pmid:10204543 |
| Paria BC et al. | Fatty-acid amide hydrolase is expressed in the mouse uterus and embryo during the periimplantation period. | 1999 | Biol. Reprod. | pmid:10208977 |
| Kiss Z | Anandamide stimulates phospholipase D activity in PC12 cells but not in NIH 3T3 fibroblasts. | 1999 | FEBS Lett. | pmid:10214947 |
| Maccarrone M et al. | Anandamide activates human platelets through a pathway independent of the arachidonate cascade. | 1999 | FEBS Lett. | pmid:10214961 |
| Yang HY et al. | GC/MS analysis of anandamide and quantification of N-arachidonoylphosphatidylethanolamides in various brain regions, spinal cord, testis, and spleen of the rat. | 1999 | J. Neurochem. | pmid:10217273 |
| Raffa RB et al. | Differential cholera-toxin sensitivity of supraspinal antinociception induced by the cannabinoid agonists delta9-THC, WIN 55,212-2 and anandamide in mice. | 1999 | Neurosci. Lett. | pmid:10218903 |
| Piomelli D et al. | Structural determinants for recognition and translocation by the anandamide transporter. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10318965 |
| Mombouli JV et al. | Anandamide-induced mobilization of cytosolic Ca2+ in endothelial cells. | 1999 | Br. J. Pharmacol. | pmid:10323591 |
| Watanabe K et al. | Pharmacological effects in mice of anandamide and its related fatty acid ethanolamides, and enhancement of cataleptogenic effect of anandamide by phenylmethylsulfonyl fluoride. | 1999 | Biol. Pharm. Bull. | pmid:10328555 |
| Mechoulam R and Ben-Shabat S | From gan-zi-gun-nu to anandamide and 2-arachidonoylglycerol: the ongoing story of cannabis. | 1999 | Nat Prod Rep | pmid:10331283 |
| Burstein SH | The cannabinoid acids: nonpsychoactive derivatives with therapeutic potential. | 1999 | Pharmacol. Ther. | pmid:10341359 |
| Williams CM and Kirkham TC | Anandamide induces overeating: mediation by central cannabinoid (CB1) receptors. | 1999 | Psychopharmacology (Berl.) | pmid:10353436 |
| Fimiani C et al. | Morphine and anandamide stimulate intracellular calcium transients in human arterial endothelial cells: coupling to nitric oxide release. | 1999 | Cell. Signal. | pmid:10353693 |
| Ng EW et al. | Unique analogues of anandamide: arachidonyl ethers and carbamates and norarachidonyl carbamates and ureas. | 1999 | J. Med. Chem. | pmid:10354405 |
| Gebremedhin D et al. | Cannabinoid CB1 receptor of cat cerebral arterial muscle functions to inhibit L-type Ca2+ channel current. | 1999 | Am. J. Physiol. | pmid:10362691 |
| Ameri A et al. | Effects of the endogeneous cannabinoid, anandamide, on neuronal activity in rat hippocampal slices. | 1999 | Br. J. Pharmacol. | pmid:10372827 |
| De Petrocellis L et al. | Finding of the endocannabinoid signalling system in Hydra, a very primitive organism: possible role in the feeding response. | 1999 | Neuroscience | pmid:10392859 |
| Zenor BN et al. | Endocrine and other responses to acute administration of cannabinoid compounds to non-stressed male calves. | 1999 | Life Sci. | pmid:10416818 |
| Di Marzo V et al. | Metabolism of anandamide and 2-arachidonoylglycerol: an historical overview and some recent developments. | 1999 | Lipids | pmid:10419192 |
| Hansen HS et al. | Formation of N-acyl-phosphatidylethanolamine and N-acylethanolamine (including anandamide) during glutamate-induced neurotoxicity. | 1999 | Lipids | pmid:10419193 |
| Ueda N et al. | An acid amidase hydrolyzing anandamide as an endogenous ligand for cannabinoid receptors. | 1999 | FEBS Lett. | pmid:10431820 |
| Zygmunt PM et al. | Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. | 1999 | Nature | pmid:10440374 |
| González S et al. | Extrapyramidal and neuroendocrine effects of AM404, an inhibitor of the carrier-mediated transport of anandamide. | 1999 | Life Sci. | pmid:10447218 |
| Melck D et al. | Unsaturated long-chain N-acyl-vanillyl-amides (N-AVAMs): vanilloid receptor ligands that inhibit anandamide-facilitated transport and bind to CB1 cannabinoid receptors. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10448105 |
| Martin BR et al. | Discovery and characterization of endogenous cannabinoids. | 1999 | Life Sci. | pmid:10462059 |
| Khanolkar AD and Makriyannis A | Structure-activity relationships of anandamide, an endogenous cannabinoid ligand. | 1999 | Life Sci. | pmid:10462061 |
| Howlett AC et al. | Signal transduction of eicosanoid CB1 receptor ligands. | 1999 | Life Sci. | pmid:10462062 |
| Di Marzo V | Biosynthesis and inactivation of endocannabinoids: relevance to their proposed role as neuromodulators. | 1999 | Life Sci. | pmid:10462065 |
| Di Marzo V et al. | Cannabimimetic fatty acid derivatives: the anandamide family and other endocannabinoids. | 1999 | Curr. Med. Chem. | pmid:10469888 |
| Molderings GJ et al. | Presynaptic cannabinoid and imidazoline receptors in the human heart and their potential relationship. | 1999 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:10494885 |
| Leweke FM et al. | Elevated endogenous cannabinoids in schizophrenia. | 1999 | Neuroreport | pmid:10501554 |
| Kuwae T et al. | Biosynthesis and turnover of anandamide and other N-acylethanolamines in peritoneal macrophages. | 1999 | FEBS Lett. | pmid:10508930 |
| Wiley JL | Cannabis: discrimination of "internal bliss"? | 1999 | Pharmacol. Biochem. Behav. | pmid:10515300 |
| Walker JM et al. | Pain modulation by release of the endogenous cannabinoid anandamide. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10518599 |
| Katayama K et al. | Equilibrium in the hydrolysis and synthesis of cannabimimetic anandamide demonstrated by a purified enzyme. | 1999 | Biochim. Biophys. Acta | pmid:10521704 |
| Chaytor AT et al. | The endothelial component of cannabinoid-induced relaxation in rabbit mesenteric artery depends on gap junctional communication. | 1999 | J. Physiol. (Lond.) | pmid:10523421 |
| McAllister SD et al. | Cannabinoid receptors can activate and inhibit G protein-coupled inwardly rectifying potassium channels in a xenopus oocyte expression system. | 1999 | J. Pharmacol. Exp. Ther. | pmid:10525080 |
| Yousif MH and Oriowo MA | Inhibitory effects of cannabinoid receptor ligands on electrically-evoked responses in rat isolated tracheal ring segments. | 1999 | Pharmacol. Res. | pmid:10527656 |
| Akinshola BE et al. | Anandamide inhibition of recombinant AMPA receptor subunits in Xenopus oocytes is increased by forskolin and 8-bromo-cyclic AMP. | 1999 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:10543424 |
| Gifford AN et al. | Potentiation of the action of anandamide on hippocampal slices by the fatty acid amide hydrolase inhibitor, palmitylsulphonyl fluoride (AM 374). | 1999 | Eur. J. Pharmacol. | pmid:10556675 |
| Járai Z et al. | Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10570211 |
| Bisogno T et al. | Biosynthesis and inactivation of N-arachidonoylethanolamine (anandamide) and N-docosahexaenoylethanolamine in bovine retina. | 1999 | Arch. Biochem. Biophys. | pmid:10577359 |
| Melck D et al. | Involvement of the cAMP/protein kinase A pathway and of mitogen-activated protein kinase in the anti-proliferative effects of anandamide in human breast cancer cells. | 1999 | FEBS Lett. | pmid:10606728 |
| Melck D et al. | Suppression of nerve growth factor Trk receptors and prolactin receptors by endocannabinoids leads to inhibition of human breast and prostate cancer cell proliferation. | 2000 | Endocrinology | pmid:10614630 |
| Sugiura T et al. | Evidence that 2-arachidonoylglycerol but not N-palmitoylethanolamine or anandamide is the physiological ligand for the cannabinoid CB2 receptor. Comparison of the agonistic activities of various cannabinoid receptor ligands in HL-60 cells. | 2000 | J. Biol. Chem. | pmid:10617657 |
| Sinor AD et al. | Endocannabinoids protect cerebral cortical neurons from in vitro ischemia in rats. | 2000 | Neurosci. Lett. | pmid:10653017 |
| Zygmunt PM et al. | Anandamide - the other side of the coin. | 2000 | Trends Pharmacol. Sci. | pmid:10664604 |
| Schmid PC et al. | A sensitive endocannabinoid assay. The simultaneous analysis of N-acylethanolamines and 2-monoacylglycerols. | 2000 | Chem. Phys. Lipids | pmid:10669310 |
| Tiger G et al. | Pharmacological properties of rat brain fatty acid amidohydrolase in different subcellular fractions using palmitoylethanolamide as substrate. | 2000 | Biochem. Pharmacol. | pmid:10677581 |
| Griffin G et al. | Cloning and pharmacological characterization of the rat CB(2) cannabinoid receptor. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10688601 |
| Rakhshan F et al. | Carrier-mediated uptake of the endogenous cannabinoid anandamide in RBL-2H3 cells. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10688610 |
| Lagalwar S et al. | Anandamides inhibit binding to the muscarinic acetylcholine receptor. | 1999 Aug-Oct | J. Mol. Neurosci. | pmid:10691292 |
| Maccarrone M et al. | Human mast cells take up and hydrolyze anandamide under the control of 5-lipoxygenase and do not express cannabinoid receptors. | 2000 | FEBS Lett. | pmid:10692582 |
| Smart D et al. | The endogenous lipid anandamide is a full agonist at the human vanilloid receptor (hVR1). | 2000 | Br. J. Pharmacol. | pmid:10694225 |
| Arai Y et al. | Sensitive determination of anandamide in rat brain utilizing a coupled-column HPLC with fluorimetric detection. | 2000 | Biomed. Chromatogr. | pmid:10694706 |
| Houser SJ et al. | Dynorphin B and spinal analgesia: induction of antinociception by the cannabinoids CP55,940, Delta(9)-THC and anandamide. | 2000 | Brain Res. | pmid:10700588 |
| Oliveira L et al. | Effects of some isoprostanes on the human umbilical artery in vitro. | 2000 | Br. J. Pharmacol. | pmid:10711349 |
| Lay L et al. | Pharmacological characterisation of cannabinoid CB(1) receptors in the rat and mouse. | 2000 | Eur. J. Pharmacol. | pmid:10720647 |
| González S et al. | Sex steroid influence on cannabinoid CB(1) receptor mRNA and endocannabinoid levels in the anterior pituitary gland. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10733937 |
| Muthian S et al. | Synthesis and characterization of a fluorescent substrate for the N-arachidonoylethanolamine (anandamide) transmembrane carrier. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10734181 |
| Wang Y et al. | Polymyxin B binds to anandamide and inhibits its cytotoxic effect. | 2000 | FEBS Lett. | pmid:10734225 |
| Di Marzo V et al. | Enhancement of anandamide formation in the limbic forebrain and reduction of endocannabinoid contents in the striatum of delta9-tetrahydrocannabinol-tolerant rats. | 2000 | J. Neurochem. | pmid:10737621 |
| Smart D and Jerman JC | Anandamide: an endogenous activator of the vanilloid receptor. | 2000 | Trends Pharmacol. Sci. | pmid:10740287 |
| Markey SP et al. | Base- and acid-catalyzed interconversions of O-acyl- and N-acyl-ethanolamines: a cautionary note for lipid analyses. | 2000 | J. Lipid Res. | pmid:10744787 |
| Rajan S et al. | TASK-3, a novel tandem pore domain acid-sensitive K+ channel. An extracellular histiding as pH sensor. | 2000 | J. Biol. Chem. | pmid:10747866 |
| Gómez del Pulgar T et al. | The CB1 cannabinoid receptor is coupled to the activation of protein kinase B/Akt. | 2000 | Biochem. J. | pmid:10749665 |
| Brăiloiu C et al. | [Endothelium-derived hyperpolarizing factor]. | 1998 Jul-Dec | Rev Med Chir Soc Med Nat Iasi | pmid:10756843 |
| Braud S et al. | Activation of rabbit blood platelets by anandamide through its cleavage into arachidonic acid. | 2000 | FEBS Lett. | pmid:10760504 |
| Hao S et al. | Low dose anandamide affects food intake, cognitive function, neurotransmitter and corticosterone levels in diet-restricted mice. | 2000 | Eur. J. Pharmacol. | pmid:10762668 |
| Lockwood CJ | Prediction of pregnancy loss. | 2000 | Lancet | pmid:10776739 |
| Maccarrone M et al. | Relation between decreased anandamide hydrolase concentrations in human lymphocytes and miscarriage. | 2000 | Lancet | pmid:10776746 |
| Beltramo M et al. | Reversal of dopamine D(2) receptor responses by an anandamide transport inhibitor. | 2000 | J. Neurosci. | pmid:10777802 |
| Gonsiorek W et al. | Endocannabinoid 2-arachidonyl glycerol is a full agonist through human type 2 cannabinoid receptor: antagonism by anandamide. | 2000 | Mol. Pharmacol. | pmid:10779390 |
| Castellano C et al. | Strain-dependent effects of anandamide on memory consolidation in mice are antagonized by naltrexone. | 1999 | Behav Pharmacol | pmid:10780251 |
| Costa B and Colleoni M | Changes in rat brain energetic metabolism after exposure to anandamide or Delta(9)-tetrahydrocannabinol. | 2000 | Eur. J. Pharmacol. | pmid:10781666 |
| Sarker KP et al. | Anandamide induces apoptosis of PC-12 cells: involvement of superoxide and caspase-3. | 2000 | FEBS Lett. | pmid:10781801 |
| Hillard CJ | Biochemistry and pharmacology of the endocannabinoids arachidonylethanolamide and 2-arachidonylglycerol. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10785538 |
| Burstein SH et al. | Oxidative metabolism of anandamide. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10785540 |
| Di Marzo V et al. | Cannabimimetic fatty acid derivatives in cancer and inflammation. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10785541 |
| Kunos G et al. | Cardiovascular effects of endocannabinoids--the plot thickens. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:10785543 |
| Hungund BL and Basavarajappa BS | Are anandamide and cannabinoid receptors involved in ethanol tolerance? A review of the evidence. | 2000 Mar-Apr | Alcohol Alcohol. | pmid:10787386 |
| Maccarrone M et al. | Anandamide uptake by human endothelial cells and its regulation by nitric oxide. | 2000 | J. Biol. Chem. | pmid:10788462 |
| Yagen B and Burstein S | Novel and sensitive method for the detection of anandamide by the use of its dansyl derivative. | 2000 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:10798298 |
| Costa B et al. | Precipitated and spontaneous withdrawal in rats tolerant to anandamide. | 2000 | Psychopharmacology (Berl.) | pmid:10805606 |
| Boger DL et al. | Exceptionally potent inhibitors of fatty acid amide hydrolase: the enzyme responsible for degradation of endogenous oleamide and anandamide. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10805767 |
| Beltramo M and Piomelli D | Carrier-mediated transport and enzymatic hydrolysis of the endogenous cannabinoid 2-arachidonylglycerol. | 2000 | Neuroreport | pmid:10817598 |
| Jarrahian A et al. | Structure-activity relationships among N-arachidonylethanolamine (Anandamide) head group analogues for the anandamide transporter. | 2000 | J. Neurochem. | pmid:10820223 |
| Davis JB et al. | Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia. | 2000 | Nature | pmid:10821274 |
| Zygmunt PM et al. | The anandamide transport inhibitor AM404 activates vanilloid receptors. | 2000 | Eur. J. Pharmacol. | pmid:10822052 |
| Zygmunt PM et al. | Differential actions of anandamide, potassium ions and endothelium-derived hyperpolarizing factor in guinea-pig basilar artery. | 2000 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:10832608 |