| MeSH term | MeSH ID | Detail |
|---|---|---|
| Stomach Ulcer | D013276 | 75 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Neoplasms | D009369 | 13 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Derkinderen P et al. | Regulation of a neuronal form of focal adhesion kinase by anandamide. | 1996 | Science | pmid:8781236 |
| Cadas H et al. | Biosynthesis of an endogenous cannabinoid precursor in neurons and its control by calcium and cAMP. | 1996 | J. Neurosci. | pmid:8656287 |
| Kempe K et al. | Isotope dilution mass spectrometric measurements indicate that arachidonylethanolamide, the proposed endogenous ligand of the cannabinoid receptor, accumulates in rat brain tissue post mortem but is contained at low levels in or is absent from fresh tissue. | 1996 | J. Biol. Chem. | pmid:8663381 |
| Stefano GB et al. | Cannabinoid receptors are coupled to nitric oxide release in invertebrate immunocytes, microglia, and human monocytes. | 1996 | J. Biol. Chem. | pmid:8702604 |
| Di Marzo V et al. | Biosynthesis of anandamide and related acylethanolamides in mouse J774 macrophages and N18 neuroblastoma cells. | 1996 | Biochem. J. | pmid:8670178 |
| Cravatt BF et al. | Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides. | 1996 | Nature | pmid:8900284 |
| Sugiura T et al. | N-arachidonoylethanolamine (anandamide), an endogenous cannabinoid receptor ligand, and related lipid molecules in the nervous tissues. | 1996 | J Lipid Mediat Cell Signal | pmid:8906545 |
| Ueda N et al. | Enzymes for anandamide biosynthesis and metabolism. | 1996 | J Lipid Mediat Cell Signal | pmid:8906546 |
| Yang ZM et al. | Activation of brain-type cannabinoid receptors interferes with preimplantation mouse embryo development. | 1996 | Biol. Reprod. | pmid:8879486 |
| Varga K et al. | Mechanism of the hypotensive action of anandamide in anesthetized rats. | 1996 | Hypertension | pmid:8843898 |
| Poling JS et al. | Anandamide, an endogenous cannabinoid, inhibits Shaker-related voltage-gated K+ channels. | 1996 | Neuropharmacology | pmid:8938728 |
| Di Marzo V et al. | Potential biosynthetic connections between the two cannabimimetic eicosanoids, anandamide and 2-arachidonoyl-glycerol, in mouse neuroblastoma cells. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8858137 |
| Ishac EJ et al. | Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB1 receptors on peripheral sympathetic nerves. | 1996 | Br. J. Pharmacol. | pmid:8864538 |
| Fride E and Mechoulam R | Ontogenetic development of the response to anandamide and delta 9-tetrahydrocannabinol in mice. | 1996 | Brain Res. Dev. Brain Res. | pmid:8873985 |
| Boring DL et al. | Cerebrodiene, arachidonyl-ethanolamide, and hybrid structures: potential for interaction with brain cannabinoid receptors. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8931121 |
| Berdyshev EV et al. | Anandamide--a new look on fatty acid ethanolamides. | 1996 | J Lipid Mediat Cell Signal | pmid:9029374 |
| Randall MD et al. | An endogenous cannabinoid as an endothelium-derived vasorelaxant. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8954092 |
| Paria BC et al. | The uterus is a potential site for anandamide synthesis and hydrolysis: differential profiles of anandamide synthase and hydrolase activities in the mouse uterus during the periimplantation period. | 1996 | Mol. Reprod. Dev. | pmid:8914076 |
| Khanolkar AD et al. | Head group analogs of arachidonylethanolamide, the endogenous cannabinoid ligand. | 1996 | J. Med. Chem. | pmid:8893848 |
| Langstein J et al. | cis-9,10-octadecenoamide, an endogenous sleep-inducing CNS compound, inhibits lymphocyte proliferation. | 1996 Jul-Aug | Res. Immunol. | pmid:8903105 |
| Thomas EA et al. | Fatty acid amide hydrolase, the degradative enzyme for anandamide and oleamide, has selective distribution in neurons within the rat central nervous system. | 1997 | J. Neurosci. Res. | pmid:9452020 |
| Hunter SA and Burstein SH | Receptor mediation in cannabinoid stimulated arachidonic acid mobilization and anandamide synthesis. | 1997 | Life Sci. | pmid:9126878 |
| Bisogno T et al. | The sleep inducing factor oleamide is produced by mouse neuroblastoma cells. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9344854 |
| Mechoulam R et al. | Anandamide may mediate sleep induction. | 1997 | Nature | pmid:9288961 |
| Hansen HS et al. | Characterization of glutamate-induced formation of N-acylphosphatidylethanolamine and N-acylethanolamine in cultured neocortical neurons. | 1997 | J. Neurochem. | pmid:9231736 |
| Castellano C et al. | The effects of anandamide on memory consolidation in mice involve both D1 and D2 dopamine receptors. | 1997 | Behav Pharmacol | pmid:9832956 |
| Wiley JL et al. | Evaluation of cannabimimetic discriminative stimulus effects of anandamide and methylated fluoroanandamide in rhesus monkeys. | 1997 | Pharmacol. Biochem. Behav. | pmid:9408225 |
| Randall MD et al. | Comparative pharmacology of endothelium-derived hyperpolarizing factor and anandamide in rat isolated mesentery. | 1997 | Eur. J. Pharmacol. | pmid:9314035 |
| Di Tomaso E et al. | Endogenous lipids that activate cannabinoid receptors. Formation and inactivation. | 1997 | Adv. Exp. Med. Biol. | pmid:9321973 |
| White R and Hiley CR | A comparison of EDHF-mediated and anandamide-induced relaxations in the rat isolated mesenteric artery. | 1997 | Br. J. Pharmacol. | pmid:9422801 |
| Zygmunt PM et al. | Studies on the effects of anandamide in rat hepatic artery. | 1997 | Br. J. Pharmacol. | pmid:9422814 |
| Jarrahian A and Hillard CJ | Arachidonylethanolamide (anandamide) binds with low affinity to dihydropyridine binding sites in brain membranes. | 1997 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9431821 |
| Sasaki T and Chang MC | N-arachidonylethanolamine (anandamide) formation from N-arachidonylphosphatidylethanolamine in rat brain membranes. | 1997 | Life Sci. | pmid:9365227 |
| Randall MD and Kendall DA | Involvement of a cannabinoid in endothelium-derived hyperpolarizing factor-mediated coronary vasorelaxation. | 1997 | Eur. J. Pharmacol. | pmid:9369375 |
| Burkey TH et al. | Relative efficacies of cannabinoid CB1 receptor agonists in the mouse brain. | 1997 | Eur. J. Pharmacol. | pmid:9384246 |
| Calignano A et al. | Potentiation of anandamide hypotension by the transport inhibitor, AM404. | 1997 | Eur. J. Pharmacol. | pmid:9389389 |
| Bloom AS et al. | Nonclassical and endogenous cannabinoids: effects on the ordering of brain membranes. | 1997 | Neurochem. Res. | pmid:9131634 |
| Deutsch DG and Makriyannis A | Inhibitors of anandamide breakdown. | 1997 | NIDA Res. Monogr. | pmid:9260184 |
| Yu M et al. | Synthesis of prostaglandin E2 ethanolamide from anandamide by cyclooxygenase-2. | 1997 | J. Biol. Chem. | pmid:9261124 |
| Welch SP | Characterization of anandamide-induced tolerance: comparison to delta 9-THC-induced interactions with dynorphinergic systems. | 1997 | Drug Alcohol Depend | pmid:9179505 |
| van der Stelt M et al. | Dioxygenation of N-linoleoyl amides by soybean lipoxygenase-1. | 1997 | FEBS Lett. | pmid:9271222 |
| Stefano GB et al. | Morphine- and anandamide-stimulated nitric oxide production inhibits presynaptic dopamine release. | 1997 | Brain Res. | pmid:9272829 |
| Schmid PC et al. | Anandamide and other N-acylethanolamines in mouse peritoneal macrophages. | 1997 | Chem. Phys. Lipids | pmid:9275307 |
| Seltzman HH et al. | Synthesis and pharmacological comparison of dimethylheptyl and pentyl analogs of anandamide. | 1997 | J. Med. Chem. | pmid:9357529 |
| Cadogan AK et al. | Influence of cannabinoids on electrically evoked dopamine release and cyclic AMP generation in the rat striatum. | 1997 | J. Neurochem. | pmid:9282935 |
| Deutsch DG et al. | Production and physiological actions of anandamide in the vasculature of the rat kidney. | 1997 | J. Clin. Invest. | pmid:9294122 |
| Kurahashi Y et al. | Reversible hydrolysis and synthesis of anandamide demonstrated by recombinant rat fatty-acid amide hydrolase. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9299394 |
| Wenger T et al. | Arachidonyl ethanolamide (anandamide) activates the parvocellular part of hypothalamic paraventricular nucleus. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9299434 |
| Wenger T et al. | The effects of prenatally administered endogenous cannabinoid on rat offspring. | 1997 | Pharmacol. Biochem. Behav. | pmid:9300616 |
| Hillard CJ et al. | Accumulation of N-arachidonoylethanolamine (anandamide) into cerebellar granule cells occurs via facilitated diffusion. | 1997 | J. Neurochem. | pmid:9231721 |
| Lake KD et al. | Cannabinoid-induced hypotension and bradycardia in rats mediated by CB1-like cannabinoid receptors. | 1997 | J. Pharmacol. Exp. Ther. | pmid:9190833 |
| Wenger T et al. | Effects of anandamide on gestation in pregnant rats. | 1997 | Life Sci. | pmid:9199480 |
| Molina-Holgado F et al. | Anandamide suppresses nitric oxide and TNF-alpha responses to Theiler's virus or endotoxin in astrocytes. | 1997 | Neuroreport | pmid:9223079 |
| Willoughby KA et al. | The biodisposition and metabolism of anandamide in mice. | 1997 | J. Pharmacol. Exp. Ther. | pmid:9223560 |
| Beltramo M et al. | Inhibition of anandamide hydrolysis in rat brain tissue by (E)-6-(bromomethylene) tetrahydro-3-(1-naphthalenyl)-2H-pyran-2-one. | 1997 | FEBS Lett. | pmid:9091314 |
| Thumser AE et al. | A fluorescence displacement assay for the measurement of arachidonoyl ethanolamide (anandamide) and oleoyl amide (octadecenoamide) hydrolysis. | 1997 | Biochem. Pharmacol. | pmid:9065749 |
| Ryan WJ et al. | Potent anandamide analogs: the effect of changing the length and branching of the end pentyl chain. | 1997 | J. Med. Chem. | pmid:9357528 |
| Bisogno T et al. | Biosynthesis, release and degradation of the novel endogenous cannabimimetic metabolite 2-arachidonoylglycerol in mouse neuroblastoma cells. | 1997 | Biochem. J. | pmid:9065792 |
| De Petrocellis L et al. | Novel inhibitors of brain, neuronal, and basophilic anandamide amidohydrolase. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9070224 |
| Deutsch DG et al. | Fatty acid sulfonyl fluorides inhibit anandamide metabolism and bind to the cannabinoid receptor. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9070252 |
| Lake KD et al. | Cardiovascular effects of anandamide in anesthetized and conscious normotensive and hypertensive rats. | 1997 | Hypertension | pmid:9149688 |
| Bisogno T et al. | Occurrence and metabolism of anandamide and related acyl-ethanolamides in ovaries of the sea urchin Paracentrotus lividus. | 1997 | Biochim. Biophys. Acta | pmid:9150253 |
| Stefano GB et al. | Identification and characterization of the leech CNS cannabinoid receptor: coupling to nitric oxide release. | 1997 | Brain Res. | pmid:9125406 |
| Mechoulam R | Todd's achievement. | 1997 | Nature | pmid:9126725 |
| Koga D et al. | Liquid chromatographic-atmospheric pressure chemical ionization mass spectrometric determination of anandamide and its analogs in rat brain and peripheral tissues. | 1997 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:9106024 |
| Schmid PC et al. | Changes in anandamide levels in mouse uterus are associated with uterine receptivity for embryo implantation. | 1997 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9108127 |
| Cadas H et al. | Occurrence and biosynthesis of endogenous cannabinoid precursor, N-arachidonoyl phosphatidylethanolamine, in rat brain. | 1997 | J. Neurosci. | pmid:9006968 |
| Sheskin T et al. | Structural requirements for binding of anandamide-type compounds to the brain cannabinoid receptor. | 1997 | J. Med. Chem. | pmid:9057852 |
| Bisogno T et al. | Biosynthesis, uptake, and degradation of anandamide and palmitoylethanolamide in leukocytes. | 1997 | J. Biol. Chem. | pmid:9013571 |
| Fowler CJ et al. | Ibuprofen inhibits the metabolism of the endogenous cannabimimetic agent anandamide. | 1997 | Pharmacol. Toxicol. | pmid:9060042 |
| Salzet M et al. | Leech immunocytes contain proopiomelanocortin: nitric oxide mediates hemolymph proopiomelanocortin processing. | 1997 | J. Immunol. | pmid:9548480 |
| Calignano A et al. | Inhibition of intestinal motility by anandamide, an endogenous cannabinoid. | 1997 | Eur. J. Pharmacol. | pmid:9537804 |
| Pate DW et al. | Effects of topical alpha-substituted anandamides on intraocular pressure in normotensive rabbits. | 1997 | Pharm. Res. | pmid:9453062 |
| Hillard CJ and Campbell WB | Biochemistry and pharmacology of arachidonylethanolamide, a putative endogenous cannabinoid. | 1997 | J. Lipid Res. | pmid:9458263 |
| Berdyshev EV et al. | Influence of fatty acid ethanolamides and delta9-tetrahydrocannabinol on cytokine and arachidonate release by mononuclear cells. | 1997 | Eur. J. Pharmacol. | pmid:9253958 |
| Soderstrom K et al. | Discovery of novel cannabinoid receptor ligands from diverse marine organisms. | 1997 | Adv. Exp. Med. Biol. | pmid:9561107 |
| Plane F et al. | Evidence that anandamide and EDHF act via different mechanisms in rat isolated mesenteric arteries. | 1997 | Br. J. Pharmacol. | pmid:9283682 |
| Fowler CJ et al. | Ibuprofen inhibits rat brain deamidation of anandamide at pharmacologically relevant concentrations. Mode of inhibition and structure-activity relationship. | 1997 | J. Pharmacol. Exp. Ther. | pmid:9353392 |
| Stark S et al. | Binding of aminoalkylindoles to noncannabinoid binding sites in NG108-15 cells. | 1997 | Cell. Mol. Neurobiol. | pmid:9353590 |
| van der Stelt M et al. | The effect of hydroxylation of linoleoyl amides on their cannabinomimetic properties. | 1997 | FEBS Lett. | pmid:9357990 |
| Beltramo M et al. | Functional role of high-affinity anandamide transport, as revealed by selective inhibition. | 1997 | Science | pmid:9262477 |
| Valk P et al. | Anandamide, a natural ligand for the peripheral cannabinoid receptor is a novel synergistic growth factor for hematopoietic cells. | 1997 | Blood | pmid:9269762 |
| Brodkin J and Moerschbaecher JM | SR141716A antagonizes the disruptive effects of cannabinoid ligands on learning in rats. | 1997 | J. Pharmacol. Exp. Ther. | pmid:9316868 |
| Twitchell W et al. | Cannabinoids inhibit N- and P/Q-type calcium channels in cultured rat hippocampal neurons. | 1997 | J. Neurophysiol. | pmid:9242259 |
| Matsuda S et al. | Metabolism of anandamide, an endogenous cannabinoid receptor ligand, in porcine ocular tissues. | 1997 | Exp. Eye Res. | pmid:9245900 |
| Fernández-Ruiz JJ et al. | Time course of the effects of different cannabimimetics on prolactin and gonadotrophin secretion: evidence for the presence of CB1 receptors in hypothalamic structures and their involvement in the effects of cannabimimetics. | 1997 | Biochem. Pharmacol. | pmid:9256167 |
| Wagner JA et al. | Activation of peripheral CB1 cannabinoid receptors in haemorrhagic shock. | 1997 | Nature | pmid:9394002 |
| Burkey RT and Nation JR | (R)-methanandamide, but not anandamide, substitutes for delta 9-THC in a drug-discrimination procedure. | 1997 | Exp Clin Psychopharmacol | pmid:9260067 |
| Compton DR and Martin BR | The effect of the enzyme inhibitor phenylmethylsulfonyl fluoride on the pharmacological effect of anandamide in the mouse model of cannabimimetic activity. | 1997 | J. Pharmacol. Exp. Ther. | pmid:9399986 |
| Stella N et al. | A second endogenous cannabinoid that modulates long-term potentiation. | 1997 | Nature | pmid:9285589 |
| Mikawa Y et al. | Ocular activity of topically administered anandamide in the rabbit. | 1997 Jul-Aug | Jpn. J. Ophthalmol. | pmid:9304433 |
| Levin M and Mercola M | Gap junctions are involved in the early generation of left-right asymmetry. | 1998 | Dev. Biol. | pmid:9806775 |
| Aceto MD et al. | Anandamide, an endogenous cannabinoid, has a very low physical dependence potential. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9808686 |
| Murillo-RodrÃguez E et al. | Anandamide modulates sleep and memory in rats. | 1998 | Brain Res. | pmid:9813364 |
| Stefano GB et al. | Macrophage behavior associated with acute and chronic exposure to HIV GP120, morphine and anandamide: endothelial implications. | 1998 | Int. J. Cardiol. | pmid:9687087 |
| Stefano GB | Autoimmunovascular regulation: morphine and anandamide and ancondamide stimulated nitric oxide release. | 1998 | J. Neuroimmunol. | pmid:9610675 |
| Smith FL et al. | Characterization of delta9-tetrahydrocannabinol and anandamide antinociception in nonarthritic and arthritic rats. | 1998 | Pharmacol. Biochem. Behav. | pmid:9610941 |
| Gurwitz D and Kloog Y | Do endogenous cannabinoids contribute to HIV-mediated immune failure? | 1998 | Mol Med Today | pmid:9612798 |
| Axelrod J and Felder CC | Cannabinoid receptors and their endogenous agonist, anandamide. | 1998 | Neurochem. Res. | pmid:9566594 |
| Randall MD and Kendall DA | Endocannabinoids: a new class of vasoactive substances. | 1998 | Trends Pharmacol. Sci. | pmid:9550942 |