| MeSH term | MeSH ID | Detail |
|---|---|---|
| Stomach Ulcer | D013276 | 75 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Neoplasms | D009369 | 13 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
Anandamide
Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.
Cross Reference
Introduction
To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Anandamide?
Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Anandamide
PubChem Associated disorders and diseases
What pathways are associated with Anandamide
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Anandamide?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Anandamide?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Anandamide?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Anandamide?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Anandamide?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Anandamide
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zhuang J et al. | The interaction of fatty acid amide hydrolase (FAAH) inhibitors with an anandamide carrier protein using (19)F-NMR. | 2013 | AAPS J | pmid:23344792 |
| Morgan CJ et al. | Cerebrospinal fluid anandamide levels, cannabis use and psychotic-like symptoms. | 2013 | Br J Psychiatry | pmid:23580381 |
| Feuerecker M et al. | Effect of an acute consumption of a moderate amount of ethanol on plasma endocannabinoid levels in humans. | 2012 May-Jun | Alcohol Alcohol. | pmid:22278319 |
| Okine BN et al. | Lack of effect of chronic pre-treatment with the FAAH inhibitor URB597 on inflammatory pain behaviour: evidence for plastic changes in the endocannabinoid system. | 2012 | Br. J. Pharmacol. | pmid:22595021 |
| Miyashita K et al. | Anandamide induces matrix metalloproteinase-2 production through cannabinoid-1 receptor and transient receptor potential vanilloid-1 in human dental pulp cells in culture. | 2012 | J Endod | pmid:22595113 |
| Vinod KY et al. | Dysfunction in fatty acid amide hydrolase is associated with depressive-like behavior in Wistar Kyoto rats. | 2012 | PLoS ONE | pmid:22606285 |
| Hutchins-Wiese HL et al. | Hind limb suspension and long-chain omega-3 PUFA increase mRNA endocannabinoid system levels in skeletal muscle. | 2012 | J. Nutr. Biochem. | pmid:22051448 |
| Haas MJ et al. | Inhibition of apolipoprotein A-I gene expression by obesity-associated endocannabinoids. | 2012 | Obesity (Silver Spring) | pmid:22016100 |
| Heyman E et al. | Intense exercise increases circulating endocannabinoid and BDNF levels in humans--possible implications for reward and depression. | 2012 | Psychoneuroendocrinology | pmid:22029953 |
| Forsell PK et al. | Metabolism of anandamide into eoxamides by 15-lipoxygenase-1 and glutathione transferases. | 2012 | Lipids | pmid:22684912 |
| Newberry EP et al. | Decreased body weight and hepatic steatosis with altered fatty acid ethanolamide metabolism in aged L-Fabp -/- mice. | 2012 | J. Lipid Res. | pmid:22327204 |
| Zhang X et al. | Agonist-dependent potentiation of vanilloid receptor transient receptor potential vanilloid type 1 function by stilbene derivatives. | 2012 | Mol. Pharmacol. | pmid:22328719 |
| Rogers TJ | The molecular basis for neuroimmune receptor signaling. | 2012 | J Neuroimmune Pharmacol | pmid:22935971 |
| Sharir H et al. | The endocannabinoids anandamide and virodhamine modulate the activity of the candidate cannabinoid receptor GPR55. | 2012 | J Neuroimmune Pharmacol | pmid:22454039 |
| Rajesh M et al. | Cannabinoid 1 receptor promotes cardiac dysfunction, oxidative stress, inflammation, and fibrosis in diabetic cardiomyopathy. | 2012 | Diabetes | pmid:22315315 |
| Shi RZ et al. | Decreased anandamide transporter activity and calcitonin gene-related peptide production in spontaneously hypertensive rats: role of angiotensin II. | 2012 | Eur. J. Pharmacol. | pmid:22318155 |
| Battista N et al. | The role of endocannabinoids in gonadal function and fertility along the evolutionary axis. | 2012 | Mol. Cell. Endocrinol. | pmid:22305972 |
| Liu J et al. | Hepatic cannabinoid receptor-1 mediates diet-induced insulin resistance via inhibition of insulin signaling and clearance in mice. | 2012 | Gastroenterology | pmid:22307032 |
| Fowler CJ | Anandamide uptake explained? | 2012 | Trends Pharmacol. Sci. | pmid:22297258 |
| Izzo AA et al. | Inhibitory effect of cannabichromene, a major non-psychotropic cannabinoid extracted from Cannabis sativa, on inflammation-induced hypermotility in mice. | 2012 | Br. J. Pharmacol. | pmid:22300105 |
| Chon SH et al. | Over-expression of monoacylglycerol lipase (MGL) in small intestine alters endocannabinoid levels and whole body energy balance, resulting in obesity. | 2012 | PLoS ONE | pmid:22937137 |
| Brown WH et al. | Fatty acid amide hydrolase ablation promotes ectopic lipid storage and insulin resistance due to centrally mediated hypothyroidism. | 2012 | Proc. Natl. Acad. Sci. U.S.A. | pmid:22912404 |
| Schreiber AK et al. | Peripheral antinociceptive effect of anandamide and drugs that affect the endocannabinoid system on the formalin test in normal and streptozotocin-diabetic rats. | 2012 | Neuropharmacology | pmid:22959964 |
| Lowin T et al. | Cortisol-mediated adhesion of synovial fibroblasts is dependent on the degradation of anandamide and activation of the endocannabinoid system. | 2012 | Arthritis Rheum. | pmid:22933357 |
| Alhouayek M and Muccioli GG | The endocannabinoid system in inflammatory bowel diseases: from pathophysiology to therapeutic opportunity. | 2012 | Trends Mol Med | pmid:22917662 |
| Sanchez AM et al. | The molecular connections between the cannabinoid system and endometriosis. | 2012 | Mol. Hum. Reprod. | pmid:22923487 |
| Thomas KC et al. | Contributions of TRPV1, endovanilloids, and endoplasmic reticulum stress in lung cell death in vitro and lung injury. | 2012 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:21949157 |
| Woodhams SG et al. | Spinal administration of the monoacylglycerol lipase inhibitor JZL184 produces robust inhibitory effects on nociceptive processing and the development of central sensitization in the rat. | 2012 | Br. J. Pharmacol. | pmid:22924700 |
| Wheal AJ et al. | Hydrogen peroxide as a mediator of vasorelaxation evoked by N-oleoylethanolamine and anandamide in rat small mesenteric arteries. | 2012 | Eur. J. Pharmacol. | pmid:22154756 |
| Li Q et al. | Effects of anandamide on potassium channels in rat ventricular myocytes: a suppression of I(to) and augmentation of K(ATP) channels. | 2012 | Am. J. Physiol., Cell Physiol. | pmid:22173869 |
| Stock K et al. | Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1. | 2012 | Nat. Med. | pmid:22820645 |
| Jang Y et al. | Axonal neuropathy-associated TRPV4 regulates neurotrophic factor-derived axonal growth. | 2012 | J. Biol. Chem. | pmid:22187434 |
| Marsicano G and Chaouloff F | Moving bliss: a new anandamide transporter. | 2012 | Nat. Neurosci. | pmid:22193249 |
| Leweke FM | Anandamide dysfunction in prodromal and established psychosis. | 2012 | Curr. Pharm. Des. | pmid:22716147 |
| Wang ZJ et al. | Cannabinoid receptor-mediated regulation of neuronal activity and signaling in glomeruli of the main olfactory bulb. | 2012 | J. Neurosci. | pmid:22723687 |
| Neelamegan D et al. | Identification and recombinant expression of anandamide hydrolyzing enzyme from Dictyostelium discoideum. | 2012 | BMC Microbiol. | pmid:22730904 |
| Moreno-Sanz G et al. | Pharmacological characterization of the peripheral FAAH inhibitor URB937 in female rodents: interaction with the Abcg2 transporter in the blood-placenta barrier. | 2012 | Br. J. Pharmacol. | pmid:22774772 |
| Rettori E et al. | Anti-inflammatory effect of the endocannabinoid anandamide in experimental periodontitis and stress in the rat. | 2012 | Neuroimmunomodulation | pmid:22777139 |
| Luchicchi A and Pistis M | Anandamide and 2-arachidonoylglycerol: pharmacological properties, functional features, and emerging specificities of the two major endocannabinoids. | 2012 | Mol. Neurobiol. | pmid:22801993 |
| Krishnan G and Chatterjee N | Endocannabinoids alleviate proinflammatory conditions by modulating innate immune response in muller glia during inflammation. | 2012 | Glia | pmid:22807196 |
| Romano MR and Lograno MD | Involvement of the peroxisome proliferator-activated receptor (PPAR) alpha in vascular response of endocannabinoids in the bovine ophthalmic artery. | 2012 | Eur. J. Pharmacol. | pmid:22429572 |
| Xiong W et al. | A common molecular basis for exogenous and endogenous cannabinoid potentiation of glycine receptors. | 2012 | J. Neurosci. | pmid:22496565 |
| Kenessey I et al. | Revisiting CB1 receptor as drug target in human melanoma. | 2012 | Pathol. Oncol. Res. | pmid:22447182 |
| Petrovszki Z et al. | The effects of peptide and lipid endocannabinoids on arthritic pain at the spinal level. | 2012 | Anesth. Analg. | pmid:22451592 |
| Tamaki C et al. | Anandamide induces endothelium-dependent vasoconstriction and CGRPergic nerve-mediated vasodilatation in the rat mesenteric vascular bed. | 2012 | J. Pharmacol. Sci. | pmid:22510966 |
| Czifra G et al. | Endocannabinoids regulate growth and survival of human eccrine sweat gland-derived epithelial cells. | 2012 | J. Invest. Dermatol. | pmid:22513781 |
| Miller LL et al. | Effects of alterations in cannabinoid signaling, alone and in combination with morphine, on pain-elicited and pain-suppressed behavior in mice. | 2012 | J. Pharmacol. Exp. Ther. | pmid:22514333 |
| Caprioli A et al. | The novel reversible fatty acid amide hydrolase inhibitor ST4070 increases endocannabinoid brain levels and counteracts neuropathic pain in different animal models. | 2012 | J. Pharmacol. Exp. Ther. | pmid:22514334 |
| Simpson CD et al. | A genome wide shRNA screen identifies α/β hydrolase domain containing 4 (ABHD4) as a novel regulator of anoikis resistance. | 2012 | Apoptosis | pmid:22488300 |
| Dubreucq S et al. | Genetic dissection of the role of cannabinoid type-1 receptors in the emotional consequences of repeated social stress in mice. | 2012 | Neuropsychopharmacology | pmid:22434220 |
| Pucci M et al. | Endocannabinoids stimulate human melanogenesis via type-1 cannabinoid receptor. | 2012 | J. Biol. Chem. | pmid:22431736 |
| McLaughlin RJ et al. | Prefrontal cortical anandamide signaling coordinates coping responses to stress through a serotonergic pathway. | 2012 | Eur Neuropsychopharmacol | pmid:22325231 |
| Monteleone P et al. | Hedonic eating is associated with increased peripheral levels of ghrelin and the endocannabinoid 2-arachidonoyl-glycerol in healthy humans: a pilot study. | 2012 | J. Clin. Endocrinol. Metab. | pmid:22442280 |
| Ritter JK et al. | Production and actions of the anandamide metabolite prostamide E2 in the renal medulla. | 2012 | J. Pharmacol. Exp. Ther. | pmid:22685343 |
| Gebeh AK et al. | Ectopic pregnancy is associated with high anandamide levels and aberrant expression of FAAH and CB1 in fallopian tubes. | 2012 | J. Clin. Endocrinol. Metab. | pmid:22701012 |
| Chianese R et al. | Anandamide regulates the expression of GnRH1, GnRH2, and GnRH-Rs in frog testis. | 2012 | Am. J. Physiol. Endocrinol. Metab. | pmid:22669247 |
| Kaczocha M et al. | Anandamide externally added to lipid vesicles containing trapped fatty acid amide hydrolase (FAAH) is readily hydrolyzed in a sterol-modulated fashion. | 2012 | ACS Chem Neurosci | pmid:22860204 |
| Tanveer R et al. | The endocannabinoid, anandamide, augments Notch-1 signaling in cultured cortical neurons exposed to amyloid-β and in the cortex of aged rats. | 2012 | J. Biol. Chem. | pmid:22891244 |
| Chicca A et al. | Evidence for bidirectional endocannabinoid transport across cell membranes. | 2012 | J. Biol. Chem. | pmid:22879589 |
| Leweke FM et al. | Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia. | 2012 | Transl Psychiatry | pmid:22832859 |
| De Petrocellis L et al. | A re-evaluation of 9-HODE activity at TRPV1 channels in comparison with anandamide: enantioselectivity and effects at other TRP channels and in sensory neurons. | 2012 | Br. J. Pharmacol. | pmid:22861649 |
| Pamplona FA and Takahashi RN | Psychopharmacology of the endocannabinoids: far beyond anandamide. | 2012 | J. Psychopharmacol. (Oxford) | pmid:21652605 |
| Gatta L et al. | Discovery of prostamide F2α and its role in inflammatory pain and dorsal horn nociceptive neuron hyperexcitability. | 2012 | PLoS ONE | pmid:22363560 |
| Kuc C et al. | Arachidonoyl ethanolamide (AEA)-induced apoptosis is mediated by J-series prostaglandins and is enhanced by fatty acid amide hydrolase (FAAH) blockade. | 2012 | Mol. Carcinog. | pmid:21432910 |
| Proto MC et al. | Interaction of endocannabinoid system and steroid hormones in the control of colon cancer cell growth. | 2012 | J. Cell. Physiol. | pmid:21412772 |
| Skaper SD and Di Marzo V | Endocannabinoids in nervous system health and disease: the big picture in a nutshell. | 2012 | Philos. Trans. R. Soc. Lond., B, Biol. Sci. | pmid:23108539 |
| Booker L et al. | The fatty acid amide hydrolase (FAAH) inhibitor PF-3845 acts in the nervous system to reverse LPS-induced tactile allodynia in mice. | 2012 | Br. J. Pharmacol. | pmid:21506952 |
| Di Marzo V and De Petrocellis L | Why do cannabinoid receptors have more than one endogenous ligand? | 2012 | Philos. Trans. R. Soc. Lond., B, Biol. Sci. | pmid:23108541 |
| Puighermanal E et al. | Cellular and intracellular mechanisms involved in the cognitive impairment of cannabinoids. | 2012 | Philos. Trans. R. Soc. Lond., B, Biol. Sci. | pmid:23108544 |
| Starowicz K and Przewlocka B | Modulation of neuropathic-pain-related behaviour by the spinal endocannabinoid/endovanilloid system. | 2012 | Philos. Trans. R. Soc. Lond., B, Biol. Sci. | pmid:23108547 |
| Rani Sagar D et al. | Dynamic changes to the endocannabinoid system in models of chronic pain. | 2012 | Philos. Trans. R. Soc. Lond., B, Biol. Sci. | pmid:23108548 |
| Campos AC et al. | Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders. | 2012 | Philos. Trans. R. Soc. Lond., B, Biol. Sci. | pmid:23108553 |
| Alvheim AR et al. | Dietary linoleic acid elevates endogenous 2-AG and anandamide and induces obesity. | 2012 | Obesity (Silver Spring) | pmid:22334255 |
| Jones BR et al. | Surrogate matrix and surrogate analyte approaches for definitive quantitation of endogenous biomolecules. | 2012 | Bioanalysis | pmid:23088461 |
| McHugh D et al. | Δ(9) -Tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells. | 2012 | Br. J. Pharmacol. | pmid:21595653 |
| Engeli S et al. | Circulating anandamide and blood pressure in patients with obstructive sleep apnea. | 2012 | J. Hypertens. | pmid:23032139 |
| Hauer D et al. | Glucocorticoid-endocannabinoid interaction in cardiac surgical patients: relationship to early cognitive dysfunction and late depression. | 2012 | Rev Neurosci | pmid:23006898 |
| Butti E et al. | Subventricular zone neural progenitors protect striatal neurons from glutamatergic excitotoxicity. | 2012 | Brain | pmid:23008234 |
| Roa-Coria JE et al. | N-(4-Methoxy-2-nitrophenyl)hexadecanamide, a palmitoylethanolamide analogue, reduces formalin-induced nociception. | 2012 | Life Sci. | pmid:23069585 |
| Jung KM et al. | An amyloid β42-dependent deficit in anandamide mobilization is associated with cognitive dysfunction in Alzheimer's disease. | 2012 | Neurobiol. Aging | pmid:21546126 |
| Scherma M et al. | The anandamide transport inhibitor AM404 reduces the rewarding effects of nicotine and nicotine-induced dopamine elevations in the nucleus accumbens shell in rats. | 2012 | Br. J. Pharmacol. | pmid:21557729 |
| Osycka-Salut C et al. | Anandamide induces sperm release from oviductal epithelia through nitric oxide pathway in bovines. | 2012 | PLoS ONE | pmid:22363468 |
| Vinod KY et al. | Innate difference in the endocannabinoid signaling and its modulation by alcohol consumption in alcohol-preferring sP rats. | 2012 | Addict Biol | pmid:21309960 |
| Lipina C et al. | New vistas for treatment of obesity and diabetes? Endocannabinoid signalling and metabolism in the modulation of energy balance. | 2012 | Bioessays | pmid:22674489 |
| Fu J et al. | A catalytically silent FAAH-1 variant drives anandamide transport in neurons. | 2012 | Nat. Neurosci. | pmid:22101642 |
| Psychoyos D et al. | Cannabinoid receptor 1 signaling in embryo neurodevelopment. | 2012 | Birth Defects Res. B Dev. Reprod. Toxicol. | pmid:22311661 |
| Zoerner AA et al. | Simultaneous UPLC-MS/MS quantification of the endocannabinoids 2-arachidonoyl glycerol (2AG), 1-arachidonoyl glycerol (1AG), and anandamide in human plasma: minimization of matrix-effects, 2AG/1AG isomerization and degradation by toluene solvent extraction. | 2012 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:21752730 |
| Sordelli MS et al. | Cyclooxygenase-2 prostaglandins mediate anandamide-inhibitory action on nitric oxide synthase activity in the receptive rat uterus. | 2012 | Eur. J. Pharmacol. | pmid:22554772 |
| Roy A et al. | Anandamide modulates carotid sinus nerve afferent activity via TRPV1 receptors increasing responses to heat. | 2012 | J. Appl. Physiol. | pmid:21903882 |
| Butler RK et al. | Fear-induced suppression of nociceptive behaviour and activation of Akt signalling in the rat periaqueductal grey: role of fatty acid amide hydrolase. | 2012 | J. Psychopharmacol. (Oxford) | pmid:21926424 |
| Czikora à et al. | Vascular metabolism of anandamide to arachidonic acid affects myogenic constriction in response to intraluminal pressure elevation. | 2012 | Life Sci. | pmid:22285599 |
| Alger BE | Endocannabinoids at the synapse a decade after the dies mirabilis (29 March 2001): what we still do not know. | 2012 | J. Physiol. (Lond.) | pmid:22289914 |
| Khasabova IA et al. | Cannabinoid type-1 receptor reduces pain and neurotoxicity produced by chemotherapy. | 2012 | J. Neurosci. | pmid:22593077 |
| Sun Y et al. | Cannabinoid receptor activation disrupts the internal structure of hippocampal sharp wave-ripple complexes. | 2012 | J. Pharmacol. Sci. | pmid:22293299 |
| Edwards JG et al. | A novel non-CB1/TRPV1 endocannabinoid-mediated mechanism depresses excitatory synapses on hippocampal CA1 interneurons. | 2012 | Hippocampus | pmid:21069781 |
| Haruta C | [Effects of anandamide on IL-11 production through the TRPV1 of human periodontal ligament cells]. | 2012 | Kokubyo Gakkai Zasshi | pmid:22568077 |
| Katona I and Freund TF | Multiple functions of endocannabinoid signaling in the brain. | 2012 | Annu. Rev. Neurosci. | pmid:22524785 |
| Tong S et al. | Diagnostic accuracy of maternal serum macrophage inhibitory cytokine-1 and pregnancy-associated plasma protein-A at 6-10 weeks of gestation to predict miscarriage. | 2012 | Obstet Gynecol | pmid:22525911 |
| Baranowska-Kuczko M et al. | Endothelium-dependent mechanisms of the vasodilatory effect of the endocannabinoid, anandamide, in the rat pulmonary artery. | 2012 | Pharmacol. Res. | pmid:22627170 |
| Gould GG et al. | Acetaminophen differentially enhances social behavior and cortical cannabinoid levels in inbred mice. | 2012 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:22542870 |