Anandamide

Anandamide is a lipid of Fatty Acyls (FA) class. Anandamide is associated with abnormalities such as Dehydration. The involved functions are known as Process, Phenomenon, Phosphorylation, Catabolic Process and Gene Expression. Anandamide often locates in Nuchal region, Microglial and Hepatic. The associated genes with Anandamide are SGPL1 gene, SPTLC1 gene, RPSA gene, KDSR gene and SMPD1 gene. The related lipids are Sphingolipids, Lipopolysaccharides, Lysophospholipids, LYSO-PC and lysophosphatidylethanolamine.

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Introduction

To understand associated biological information of Anandamide, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Anandamide?

Anandamide is suspected in Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Anandamide

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Breast Neoplasms D001943 24 associated lipids
Neoplasms D009369 13 associated lipids
Pain D010146 64 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Anandamide

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Anandamide?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Anandamide?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Anandamide?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Anandamide?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Anandamide?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Anandamide

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Per page 10 20 50 100 | Total 2222
Authors Title Published Journal PubMed Link
Bornheim LM et al. Microsomal cytochrome P450-mediated liver and brain anandamide metabolism. 1995 Biochem. Pharmacol. pmid:7669071
Desarnaud F et al. Anandamide amidohydrolase activity in rat brain microsomes. Identification and partial characterization. 1995 J. Biol. Chem. pmid:7890734
Hillard CJ et al. Characterization of the kinetics and distribution of N-arachidonylethanolamine (anandamide) hydrolysis by rat brain. 1995 Biochim. Biophys. Acta pmid:7647100
Fride E et al. Low doses of anandamides inhibit pharmacological effects of delta 9-tetrahydrocannabinol. 1995 J. Pharmacol. Exp. Ther. pmid:7853184
Adams IB et al. Evaluation of cannabinoid receptor binding and in vivo activities for anandamide analogs. 1995 J. Pharmacol. Exp. Ther. pmid:7791088
Welch SP et al. Characterization of anandamide- and fluoroanandamide-induced antinociception and cross-tolerance to delta 9-THC after intrathecal administration to mice: blockade of delta 9-THC-induced antinociception. 1995 J. Pharmacol. Exp. Ther. pmid:7791096
Musty RE et al. A review of recent advances in cannabinoid research and the 1994 International Symposium on Cannabis and the Cannabinoids. 1995 Life Sci. pmid:7776816
Omeir RL et al. Arachidonoyl ethanolamide-[1,2-14C] as a substrate for anandamide amidase. 1995 Life Sci. pmid:7776824
Romero J et al. The endogenous cannabinoid receptor ligand, anandamide, inhibits the motor behavior: role of nigrostriatal dopaminergic neurons. 1995 Life Sci. pmid:7776829
Adams IB et al. Pharmacological and behavioral evaluation of alkylated anandamide analogs. 1995 Life Sci. pmid:7776830
Wenger T et al. Effects of anandamide (endogen cannabinoid) on anterior pituitary hormone secretion in adult ovariectomized rats. 1995 Life Sci. pmid:7776832
Cabral GA et al. Anandamide inhibits macrophage-mediated killing of tumor necrosis factor-sensitive cells. 1995 Life Sci. pmid:7776833
Wiley J et al. Discriminative stimulus effects of anandamide in rats. 1995 Eur. J. Pharmacol. pmid:7781695
Di Marzo V and Fontana A Anandamide, an endogenous cannabinomimetic eicosanoid: 'killing two birds with one stone'. 1995 Prostaglandins Leukot. Essent. Fatty Acids pmid:7675818
Romero J et al. Changes in rat brain cannabinoid binding sites after acute or chronic exposure to their endogenous agonist, anandamide, or to delta 9-tetrahydrocannabinol. 1995 Pharmacol. Biochem. Behav. pmid:7675852
Das SK et al. Cannabinoid ligand-receptor signaling in the mouse uterus. 1995 Proc. Natl. Acad. Sci. U.S.A. pmid:7753807
Fan P Cannabinoid agonists inhibit the activation of 5-HT3 receptors in rat nodose ganglion neurons. 1995 J. Neurophysiol. pmid:7760148
Ueda N et al. Oxygenation of arachidonylethanolamide (anandamide) by lipoxygenases. 1995 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:7732825
Facci L et al. Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide. 1995 Proc. Natl. Acad. Sci. U.S.A. pmid:7724569
Fride E Anandamides: tolerance and cross-tolerance to delta 9-tetrahydrocannabinol. 1995 Brain Res. pmid:8593598
Fontana A et al. Analysis of anandamide, an endogenous cannabinoid substance, and of other natural N-acylethanolamines. 1995 Prostaglandins Leukot. Essent. Fatty Acids pmid:8577784
Barg J et al. Cannabinomimetic behavioral effects of and adenylate cyclase inhibition by two new endogenous anandamides. 1995 Eur. J. Pharmacol. pmid:8749028
Terranova JP et al. Inhibition of long-term potentiation in rat hippocampal slices by anandamide and WIN55212-2: reversal by SR141716 A, a selective antagonist of CB1 cannabinoid receptors. 1995 Naunyn Schmiedebergs Arch. Pharmacol. pmid:8751088
Lee M et al. Effects of putative cannabinoid receptor ligands, anandamide and 2-arachidonyl-glycerol, on immune function in B6C3F1 mouse splenocytes. 1995 J. Pharmacol. Exp. Ther. pmid:7473135
Schmid PC et al. Occurrence and postmortem generation of anandamide and other long-chain N-acylethanolamines in mammalian brain. 1995 FEBS Lett. pmid:7498458
Sugiura T et al. 2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain. 1995 Biochem. Biophys. Res. Commun. pmid:7575630
Guzmán M et al. Effects of anandamide on hepatic fatty acid metabolism. 1995 Biochem. Pharmacol. pmid:7575652
Ueda N et al. Partial purification and characterization of the porcine brain enzyme hydrolyzing and synthesizing anandamide. 1995 J. Biol. Chem. pmid:7559559
Venance L et al. Inhibition by anandamide of gap junctions and intercellular calcium signalling in striatal astrocytes. 1995 Nature pmid:7637807
Ueda N [Anandamide: an endogenous cannabinoid receptor agonist]. 1995 Seikagaku pmid:7594870
Varga K et al. Novel antagonist implicates the CB1 cannabinoid receptor in the hypotensive action of anandamide. 1995 Eur. J. Pharmacol. pmid:7589169
Mechoulam R et al. Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors. 1995 Biochem. Pharmacol. pmid:7605349
Felder CC et al. Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors. 1995 Mol. Pharmacol. pmid:7565624
Vela G et al. Anandamide decreases naloxone-precipitated withdrawal signs in mice chronically treated with morphine. 1995 Neuropharmacology pmid:7566503
Paria BC et al. The preimplantation mouse embryo is a target for cannabinoid ligand-receptor signaling. 1995 Proc. Natl. Acad. Sci. U.S.A. pmid:7568154
Burstein SH and Hunter SA Stimulation of anandamide biosynthesis in N-18TG2 neuroblastoma cells by delta 9-tetrahydrocannabinol (THC). 1995 Biochem. Pharmacol. pmid:7702643
Priller J et al. Mead ethanolamide, a novel eicosanoid, is an agonist for the central (CB1) and peripheral (CB2) cannabinoid receptors. 1995 Mol. Pharmacol. pmid:7651362
Collin C et al. Long-term synaptic transformation of hippocampal CA1 gamma-aminobutyric acid synapses and the effect of anandamide. 1995 Proc. Natl. Acad. Sci. U.S.A. pmid:7479747
Pertwee RG et al. Effect of phenylmethylsulphonyl fluoride on the potency of anandamide as an inhibitor of electrically evoked contractions in two isolated tissue preparations. 1995 Eur. J. Pharmacol. pmid:7713152
Hansen HS et al. Glutamate stimulates the formation of N-acylphosphatidylethanolamine and N-acylethanolamine in cortical neurons in culture. 1995 Biochim. Biophys. Acta pmid:7548201
Weidenfeld J et al. Effect of the brain constituent anandamide, a cannabinoid receptor agonist, on the hypothalamo-pituitary-adrenal axis in the rat. 1994 Neuroendocrinology pmid:8127398
Childers SR et al. Effects of anandamide on cannabinoid receptors in rat brain membranes. 1994 Biochem. Pharmacol. pmid:8129747
Devane WA New dawn of cannabinoid pharmacology. 1994 Trends Pharmacol. Sci. pmid:8165721
Iversen L Pharmacology. Endogenous cannabinoids. 1994 Nature pmid:7990950
Van der Kloot W Anandamide, a naturally-occurring agonist of the cannabinoid receptor, blocks adenylate cyclase at the frog neuromuscular junction. 1994 Brain Res. pmid:7953630
Di Marzo V et al. Formation and inactivation of endogenous cannabinoid anandamide in central neurons. 1994 Nature pmid:7990962
Smith PB et al. The pharmacological activity of anandamide, a putative endogenous cannabinoid, in mice. 1994 J. Pharmacol. Exp. Ther. pmid:8035318
Mechoulam R et al. Search for endogenous ligands of the cannabinoid receptor. 1994 Biochem. Pharmacol. pmid:7980618
Koutek B et al. Inhibitors of arachidonoyl ethanolamide hydrolysis. 1994 J. Biol. Chem. pmid:8083191
Kruszka KK and Gross RW The ATP- and CoA-independent synthesis of arachidonoylethanolamide. A novel mechanism underlying the synthesis of the endogenous ligand of the cannabinoid receptor. 1994 J. Biol. Chem. pmid:8182035